scholarly article | Q13442814 |
review article | Q7318358 |
P50 | author | Peter C. Bull | Q47502958 |
Abdirahman Abdi | Q43162269 | ||
P2093 | author name string | ABDIRAHMAN I. ABDI | |
PETER C. BULL | |||
P2860 | cites work | Immunity to malaria: more questions than answers | Q37194482 |
Identification of residues in the Cmu4 domain of polymeric IgM essential for interaction with Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1). | Q37226958 | ||
Failure to respond to the surface of Plasmodium falciparum infected erythrocytes predicts susceptibility to clinical malaria amongst African children | Q37229848 | ||
Parasite antigens on the infected red cell surface are targets for naturally acquired immunity to malaria. | Q37331646 | ||
Immune selection and within-host competition can structure the repertoire of variant surface antigens in Plasmodium falciparum--a mathematical model | Q21562686 | ||
Genome sequence of the human malaria parasite Plasmodium falciparum | Q22122524 | ||
Wagner-Jauregg and fever therapy | Q24797148 | ||
Sub-grouping of Plasmodium falciparum 3D7 var genes based on sequence analysis of coding and non-coding regions | Q24804747 | ||
Plasmodium falciparum variant surface antigen expression patterns during malaria | Q24811060 | ||
The role of PfEMP1 adhesion domain classification in Plasmodium falciparum pathogenesis research | Q26862567 | ||
The Cysteine-Rich Interdomain Region from the Highly Variable Plasmodium falciparum Erythrocyte Membrane Protein-1 Exhibits a Conserved Structure | Q27651999 | ||
Structural Basis for the ABO Blood-Group Dependence of Plasmodium falciparum Rosetting | Q27670781 | ||
RIFINs are adhesins implicated in severe Plasmodium falciparum malaria | Q27972159 | ||
Rifins: a second family of clonally variant proteins expressed on the surface of red cells infected with Plasmodium falciparum | Q27972160 | ||
P. falciparum rosetting mediated by a parasite-variant erythrocyte membrane protein and complement-receptor 1 | Q27972544 | ||
STEVOR is a Plasmodium falciparum erythrocyte binding protein that mediates merozoite invasion and rosetting | Q27972547 | ||
A Plasmodium falciparum histone deacetylase regulates antigenic variation and gametocyte conversion | Q27974382 | ||
Heterochromatin protein 1 secures survival and transmission of malaria parasites | Q27974686 | ||
Selective upregulation of a single distinctly structured var gene in chondroitin sulphate A-adhering Plasmodium falciparum involved in pregnancy-associated malaria | Q27976511 | ||
Immunity to non-cerebral severe malaria is acquired after one or two infections | Q28139257 | ||
Expression of the domain cassette 8 Plasmodium falciparum erythrocyte membrane protein 1 is associated with cerebral malaria in Benin | Q28534938 | ||
The large diverse gene family var encodes proteins involved in cytoadherence and antigenic variation of plasmodium falciparum-infected erythrocytes | Q29393314 | ||
Cloning the P. falciparum gene encoding PfEMP1, a malarial variant antigen and adherence receptor on the surface of parasitized human erythrocytes | Q29618254 | ||
Switches in expression of Plasmodium falciparum var genes correlate with changes in antigenic and cytoadherent phenotypes of infected erythrocytes | Q29618991 | ||
A transcriptional switch underlies commitment to sexual development in malaria parasites | Q30041370 | ||
Genome sequencing of chimpanzee malaria parasites reveals possible pathways of adaptation to human hosts. | Q30430428 | ||
Evasion of immunity to Plasmodium falciparum malaria by IgM masking of protective IgG epitopes in infected erythrocyte surface-exposed PfEMP1 | Q30502964 | ||
Antigen reversal identifies targets of opsonizing IgGs against pregnancy-associated malaria | Q30603697 | ||
Geographical and temporal conservation of antibody recognition of Plasmodium falciparum variant surface antigens | Q31064176 | ||
Plasmodium falciparum var gene expression homogeneity as a marker of the host-parasite relationship under different levels of naturally acquired immunity to malaria | Q31125954 | ||
Epitope mapping and topographic analysis of VAR2CSA DBL3X involved in P. falciparum placental sequestration | Q33263953 | ||
Patterns of gene recombination shape var gene repertoires in Plasmodium falciparum: comparisons of geographically diverse isolates | Q33272663 | ||
Population genomics of the immune evasion (var) genes of Plasmodium falciparum | Q33279159 | ||
Plasmodium falciparum erythrocyte membrane protein 1 diversity in seven genomes--divide and conquer | Q33700519 | ||
The role of variant surface antigens on malaria-infected red blood cells. | Q33746986 | ||
Age-related buildup of humoral immunity against epitopes for rosette formation and agglutination in African areas of malaria endemicity | Q33765361 | ||
A var gene upstream element controls protein synthesis at the level of translation initiation in Plasmodium falciparum | Q33769247 | ||
MHC polymorphism and parasites. | Q54191001 | ||
Acquired immunity and postnatal clinical protection in childhood cerebral malaria | Q56830923 | ||
Plasmodium falciparum parasitaemia described by a new mathematical model. | Q47882129 | ||
Antigens induced on erythrocytes by P. falciparum: expression of diverse and conserved determinants | Q47886673 | ||
Plasmodium falciparum variant surface antigen expression varies between isolates causing severe and nonsevere malaria and is modified by acquired immunity | Q47901577 | ||
The Plasmodium falciparum var gene transcription strategy at the onset of blood stage infection in a human volunteer | Q47909162 | ||
Widespread functional specialization of Plasmodium falciparum erythrocyte membrane protein 1 family members to bind CD36 analysed across a parasite genome | Q47923917 | ||
Evidence for the importance of genetic structuring to the structural and functional specialization of the Plasmodium falciparum var gene family | Q47971150 | ||
Analysis of adhesive domains from the A4VAR Plasmodium falciparum erythrocyte membrane protein-1 identifies a CD36 binding domain | Q47996636 | ||
Protection against clinical malaria by heterologous immunoglobulin G antibodies against malaria-infected erythrocyte variant surface antigens requires interaction with asymptomatic infections | Q47997112 | ||
Identification of Id1-DBL2X of VAR2CSA as a key domain inducing highly inhibitory and cross-reactive antibodies | Q47999224 | ||
Plasmodium falciparum antigenic variation: relationships between in vivo selection, acquired antibody response, and disease severity | Q48014091 | ||
Serological diversity of antigens expressed on the surface of erythrocytes infected with Plasmodium falciparum | Q48018798 | ||
Gradual acquisition of immunity to severe malaria with increasing exposure. | Q50983969 | ||
Immunogen design for HIV-1 and influenza. | Q51846035 | ||
Plasmodium falciparum var gene expression is modified by host immunity | Q37471820 | ||
Antigenic variation in Plasmodium falciparum | Q37607771 | ||
Rosetting Plasmodium falciparum-infected erythrocytes bind to human brain microvascular endothelial cells in vitro, demonstrating a dual adhesion phenotype mediated by distinct P. falciparum erythrocyte membrane protein 1 domains. | Q37643887 | ||
Llama immunization with full-length VAR2CSA generates cross-reactive and inhibitory single-domain antibodies against the DBL1X domain | Q37734391 | ||
The age patterns of severe malaria syndromes in sub-Saharan Africa across a range of transmission intensities and seasonality settings | Q37799657 | ||
Sequence variation and structural conservation allows development of novel function and immune evasion in parasite surface protein families | Q38180023 | ||
Conserved immunogens in prime-boost strategies for the next-generation HIV-1 vaccines | Q38184579 | ||
Immunization with PfEMP1-DBL1alpha generates antibodies that disrupt rosettes and protect against the sequestration of Plasmodium falciparum-infected erythrocytes | Q38339089 | ||
Analysis of Plasmodium falciparum var genes expressed in children from Papua New Guinea | Q38998322 | ||
Receptor-specific adhesion and clinical disease in Plasmodium falciparum | Q39115353 | ||
Differential var gene expression in children with malaria and antidromic effects on host gene expression | Q39116665 | ||
Plasmodium falciparum infections are associated with agglutinating antibodies to parasite-infected erythrocyte surface antigens among healthy Kenyan children | Q39123150 | ||
Recombinant Duffy binding-like-alpha domains of Plasmodium falciparum erythrocyte membrane protein 1 elicit antibodies in rats that recognise conserved epitopes | Q39318009 | ||
Investigating the function of Fc-specific binding of IgM to Plasmodium falciparum erythrocyte membrane protein 1 mediating erythrocyte rosetting | Q39490520 | ||
Low antibody responses to variant surface antigens of Plasmodium falciparum are associated with severe malaria and increased susceptibility to malaria attacks in Gabonese children. | Q39515251 | ||
Fresh isolates from children with severe Plasmodium falciparum malaria bind to multiple receptors. | Q39522091 | ||
Immunoglobulin G isotype responses to erythrocyte surface-expressed variant antigens of Plasmodium falciparum predict protection from malaria in African children | Q39616918 | ||
Plasmodium falciparum rosetting is associated with malaria severity in Kenya | Q39822248 | ||
How selection forces dictate the variant surface antigens used by malaria parasites | Q39932709 | ||
Julius Wagner-Jauregg (1857-1940): Introducing fever therapy in the treatment of neurosyphilis | Q40229604 | ||
Determinant spreading and the dynamics of the autoimmune T-cell repertoire. | Q40487702 | ||
Human cerebral malaria: association with erythrocyte rosetting and lack of anti-rosetting antibodies | Q41175606 | ||
Diversity of antigens expressed on the surface of erythrocytes infected with mature Plasmodium falciparum parasites in Papua New Guinea | Q41298484 | ||
Prognostic indicators of life-threatening malaria are associated with distinct parasite variant antigen profiles | Q41400361 | ||
Diversity of agglutinating phenotype, cytoadherence, and rosette-forming characteristics of Plasmodium falciparum isolates from Papua New Guinean children. | Q41456213 | ||
var gene transcription and PfEMP1 expression in the rosetting and cytoadhesive Plasmodium falciparum clone FCR3S1.2. | Q41897345 | ||
Rapid switching to multiple antigenic and adhesive phenotypes in malaria | Q41904261 | ||
Sex: how malaria parasites get turned on. | Q42216431 | ||
stevor and rif are Plasmodium falciparum multicopy gene families which potentially encode variant antigens | Q42689345 | ||
3D7-Derived Plasmodium falciparum erythrocyte membrane protein 1 is a frequent target of naturally acquired antibodies recognizing protein domains in a particular pattern independent of malaria transmission intensity | Q43946217 | ||
Agglutination of Plasmodium falciparum-infected erythrocytes from east and west African isolates by human sera from distant geographic regions | Q43955580 | ||
The sound of sexual commitment breaks the silencing of malaria parasites | Q44145958 | ||
Antibodies to blood stage antigens of Plasmodium falciparum in rural Gambians and their relation to protection against infection | Q44147641 | ||
Differential adhesion-inhibitory patterns of antibodies raised against two major variants of the NTS-DBL2X region of VAR2CSA. | Q44227448 | ||
Sequential, ordered acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 domains | Q44605152 | ||
Differentiating the pathologies of cerebral malaria by postmortem parasite counts | Q44772302 | ||
Antibodies to variable Plasmodium falciparum-infected erythrocyte surface antigens are associated with protection from novel malaria infections | Q46184700 | ||
Immunization of Aotus monkeys with recombinant cysteine-rich interdomain region 1 alpha protects against severe disease during Plasmodium falciparum reinfection | Q46226456 | ||
The NTS-DBL2X region of VAR2CSA induces cross-reactive antibodies that inhibit adhesion of several Plasmodium falciparum isolates to chondroitin sulfate A. | Q46326711 | ||
Plasmodium falciparum-infected erythrocytes: agglutination by diverse Kenyan plasma is associated with severe disease and young host age. | Q46809348 | ||
Allelic diversity of the Plasmodium falciparum erythrocyte membrane protein 1 entails variant-specific red cell surface epitopes | Q33813188 | ||
Specific receptor usage in Plasmodium falciparum cytoadherence is associated with disease outcome | Q33842019 | ||
Virulence of malaria is associated with differential expression of Plasmodium falciparum var gene subgroups in a case-control study | Q33879876 | ||
Parasite burden and severity of malaria in Tanzanian children | Q33882158 | ||
Adhesion of Plasmodium falciparum-infected erythrocytes to human cells: molecular mechanisms and therapeutic implications. | Q33884983 | ||
Identification of a Plasmodium falciparum intercellular adhesion molecule-1 binding domain: a parasite adhesion trait implicated in cerebral malaria | Q33890328 | ||
Investigating the host binding signature on the Plasmodium falciparum PfEMP1 protein family | Q33900642 | ||
Evidence of promiscuous endothelial binding by Plasmodium falciparum-infected erythrocytes | Q33967171 | ||
Antibody recognition of Plasmodium falciparum erythrocyte surface antigens in Kenya: evidence for rare and prevalent variants. | Q34000292 | ||
Antibodies to variant antigens on the surfaces of infected erythrocytes are associated with protection from malaria in Ghanaian children. | Q34007707 | ||
Immunization of Aotus monkeys with a functional domain of the Plasmodium falciparum variant antigen induces protection against a lethal parasite line | Q34020876 | ||
Surface antigens of Plasmodium falciparum-infected erythrocytes as immune targets and malaria vaccine candidates | Q34161839 | ||
Evolution of the multi-domain structures of virulence genes in the human malaria parasite, Plasmodium falciparum | Q34236544 | ||
Induction of strain-transcending antibodies against Group A PfEMP1 surface antigens from virulent malaria parasites | Q34244920 | ||
Plasmodium falciparum erythrocyte membrane protein 1 domain cassettes 8 and 13 are associated with severe malaria in children | Q34276755 | ||
A restricted subset of var genes mediates adherence of Plasmodium falciparum-infected erythrocytes to brain endothelial cells | Q34276761 | ||
A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cells | Q34276770 | ||
Hierarchical, domain type-specific acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 in Tanzanian children | Q34290645 | ||
A novel domain cassette identifies Plasmodium falciparum PfEMP1 proteins binding ICAM-1 and is a target of cross-reactive, adhesion-inhibitory antibodies | Q34315378 | ||
Severe malaria is associated with parasite binding to endothelial protein C receptor | Q34348881 | ||
Identification of a region of PfEMP1 that mediates adherence of Plasmodium falciparum infected erythrocytes to CD36: conserved function with variant sequence | Q34443957 | ||
Structural conservation despite huge sequence diversity allows EPCR binding by the PfEMP1 family implicated in severe childhood malaria | Q34452432 | ||
The surface variant antigens of Plasmodium falciparum contain cross-reactive epitopes | Q34482933 | ||
Plasmodium falciparum rosetting epitopes converge in the SD3-loop of PfEMP1-DBL1α. | Q34507076 | ||
A sequence in subdomain 2 of DBL1α of Plasmodium falciparum erythrocyte membrane protein 1 induces strain transcending antibodies | Q34555650 | ||
Differential var gene transcription in Plasmodium falciparum isolates from patients with cerebral malaria compared to hyperparasitaemia | Q34568283 | ||
B-cell epitopes in NTS-DBL1α of PfEMP1 recognized by human antibodies in Rosetting Plasmodium falciparum | Q34599635 | ||
Differential PfEMP1 expression is associated with cerebral malaria pathology | Q34633859 | ||
Differences in gene transcriptomic pattern of Plasmodium falciparum in children with cerebral malaria and asymptomatic carriers | Q34640524 | ||
Evaluating controlled human malaria infection in Kenyan adults with varying degrees of prior exposure to Plasmodium falciparum using sporozoites administered by intramuscular injection | Q34687174 | ||
Differential expression of var gene groups is associated with morbidity caused by Plasmodium falciparum infection in Tanzanian children | Q34721291 | ||
Hypervariable antigen genes in malaria have ancient roots | Q34751031 | ||
Plasmodium falciparum expressing domain cassette 5 type PfEMP1 (DC5-PfEMP1) bind PECAM1. | Q34853037 | ||
VAR2CSA signatures of high Plasmodium falciparum parasitemia in the placenta | Q34921119 | ||
Diversity and virulence thresholds in AIDS. | Q34983038 | ||
Using the PfEMP1 head structure binding motif to deal a blow at severe malaria | Q35091763 | ||
Virulence and transmission success of the malarial parasite Plasmodium falciparum | Q35132510 | ||
Virulence in malaria: an evolutionary viewpoint | Q35213982 | ||
Limited cross-reactivity among domains of the Plasmodium falciparum clone 3D7 erythrocyte membrane protein 1 family | Q35220304 | ||
Impact of malaria preexposure on antiparasite cellular and humoral immune responses after controlled human malaria infection | Q35439859 | ||
Generation of antigenic diversity in Plasmodium falciparum by structured rearrangement of Var genes during mitosis | Q35529234 | ||
A review of hyperendemic malaria | Q35654736 | ||
Generation of cross-protective antibodies against Plasmodium falciparum sequestration by immunization with an erythrocyte membrane protein 1-duffy binding-like 1 alpha domain | Q35688950 | ||
Immunoglobulin G antibody reactivity to a group A Plasmodium falciparum erythrocyte membrane protein 1 and protection from P. falciparum malaria | Q35783951 | ||
Why do some African children develop severe malaria? | Q35907971 | ||
PfEMP1-DBL1alpha amino acid motifs in severe disease states of Plasmodium falciparum malaria | Q36013437 | ||
Structural and functional insight into how the Plasmodium falciparum VAR2CSA protein mediates binding to chondroitin sulfate A in placental malaria. | Q36078717 | ||
Association of severe noncerebral Plasmodium falciparum malaria in Brazil with expressed PfEMP1 DBL1 alpha sequences lacking cysteine residues | Q36087903 | ||
Malaria--a neglected disease? | Q36127074 | ||
Epigenetic dysregulation of virulence gene expression in severe Plasmodium falciparum malaria | Q36153793 | ||
Targets of antibodies against Plasmodium falciparum-infected erythrocytes in malaria immunity | Q36190707 | ||
Antigenicity of the infected-erythrocyte and merozoite surfaces in Falciparum malaria | Q36343017 | ||
Splenic requirement for antigenic variation and expression of the variant antigen on the erythrocyte membrane in cloned Plasmodium knowlesi malaria | Q36348229 | ||
Small, clonally variant antigens expressed on the surface of the Plasmodium falciparum-infected erythrocyte are encoded by the rif gene family and are the target of human immune responses | Q36375576 | ||
Plasmodium falciparum associated with severe childhood malaria preferentially expresses PfEMP1 encoded by group A var genes | Q36399515 | ||
Barriers to antigenic escape by pathogens: trade-off between reproductive rate and antigenic mutability. | Q36412729 | ||
Induction of crossreactive antibodies against the Plasmodium falciparum variant protein | Q36690071 | ||
Plasmodium falciparum antigenic variation. Mapping mosaic var gene sequences onto a network of shared, highly polymorphic sequence blocks | Q36737443 | ||
Plasmodium falciparum isolates from infected pregnant women and children are associated with distinct adhesive and antigenic properties | Q37036123 | ||
Loss of endothelial protein C receptors links coagulation and inflammation to parasite sequestration in cerebral malaria in African children | Q37065724 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Plasmodium falciparum | Q311383 |
malaria vaccine | Q6741353 | ||
Plasmodium falciparum malaria | Q18554672 | ||
protozoan proteins | Q76505803 | ||
malaria | Q12156 | ||
eukaryote | Q19088 | ||
P5008 | on focus list of Wikimedia project | ScienceSource | Q55439927 |
P304 | page(s) | 171-186 | |
P577 | publication date | 2016-02-01 | |
P1433 | published in | Parasitology | Q15753259 |
P1476 | title | The role of PfEMP1 as targets of naturally acquired immunity to childhood malaria: prospects for a vaccine | |
P478 | volume | 143 |
Q64055939 | Age-dependent increase in antibodies that inhibit Plasmodium falciparum adhesion to a subset of endothelial receptors |
Q33899922 | An exported protein-interacting complex involved in the trafficking of virulence determinants in Plasmodium-infected erythrocytes |
Q56358597 | Antibodies to Intercellular Adhesion Molecule 1-Binding Plasmodium falciparum Erythrocyte Membrane Protein 1-DBLβ Are Biomarkers of Protective Immunity to Malaria in a Cohort of Young Children from Papua New Guinea |
Q64360526 | Associations between IgG reactivity to Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) antigens and Burkitt lymphoma in Ghana and Uganda case-control studies |
Q91820560 | Comprehensive analysis of antibody responses to Plasmodium falciparum erythrocyte membrane protein 1 domains |
Q64124835 | Distinct amino acid and lipid perturbations characterize acute versus chronic malaria |
Q46237821 | Do we know enough to find an adjunctive therapy for cerebral malaria in African children? |
Q36294168 | Effects of sevuparin on rosette formation and cytoadherence of Plasmodium falciparum infected erythrocytes |
Q93103317 | From genomic to LC-MS/MS evidence: Analysis of PfEMP1 in Benin malaria cases |
Q44169469 | Host immune evasion strategies of malaria blood stage parasite |
Q56340290 | Immunization with Recombinant Plasmodium falciparum Erythrocyte Membrane Protein 1 CIDRα1 Domains Induces Domain Subtype Inhibitory Antibodies. |
Q50095537 | Natural and vaccine-induced acquisition of cross-reactive IgG inhibiting ICAM-1-specific binding of a PfEMP1 subtype associated specifically with cerebral malaria |
Q40082198 | Plasmodium falciparum malaria parasite var gene expression is modified by host antibodies: longitudinal evidence from controlled infections of Kenyan adults with varying natural exposure |
Q91971710 | Sticking for a Cause: The Falciparum Malaria Parasites Cytoadherence Paradigm |
Q91883983 | The knob protein KAHRP assembles into a ring-shaped structure that underpins virulence complex assembly |
Q39365658 | Variant surface antigens of Plasmodium falciparum and their roles in severe malaria |