Immunoglobulin G antibody reactivity to a group A Plasmodium falciparum erythrocyte membrane protein 1 and protection from P. falciparum malaria

scientific article published on 5 February 2007

Immunoglobulin G antibody reactivity to a group A Plasmodium falciparum erythrocyte membrane protein 1 and protection from P. falciparum malaria is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/IAI.00951-06
P932PMC publication ID1865733
P698PubMed publication ID17283085

P50authorLouise TurnerQ43240630
Thor G. TheanderQ54802168
Lars HviidQ55174838
Thomas LavstsenQ80377133
Martha M LemngeQ87131272
John LusinguQ90228924
Lasse S VestergaardQ114320005
Pamela MagistradoQ114320963
P2093author name stringAnja T R Jensen
P2860cites workGenome sequence of the human malaria parasite Plasmodium falciparumQ22122524
The var genes of Plasmodium falciparum are located in the subtelomeric region of most chromosomesQ24562131
Malaria morbidity and immunity among residents of villages with different Plasmodium falciparum transmission intensity in North-Eastern TanzaniaQ24800714
Expression of Plasmodium falciparum erythrocyte membrane protein 1 in experimentally infected humansQ24804115
Sub-grouping of Plasmodium falciparum 3D7 var genes based on sequence analysis of coding and non-coding regionsQ24804747
Plasmodium falciparum variant surface antigen expression patterns during malariaQ24811060
Selective upregulation of a single distinctly structured var gene in chondroitin sulphate A-adhering Plasmodium falciparum involved in pregnancy-associated malariaQ27976511
Immunity to non-cerebral severe malaria is acquired after one or two infectionsQ28139257
The large diverse gene family var encodes proteins involved in cytoadherence and antigenic variation of plasmodium falciparum-infected erythrocytesQ29393314
Cloning the P. falciparum gene encoding PfEMP1, a malarial variant antigen and adherence receptor on the surface of parasitized human erythrocytesQ29618254
Transcription of multiple var genes by individual, trophozoite-stage Plasmodium falciparum cells expressing a chondroitin sulphate A binding phenotypeQ30828703
Geographical and temporal conservation of antibody recognition of Plasmodium falciparum variant surface antigensQ31064176
Parasite virulence factors during falciparum malaria: rosetting, cytoadherence, and modulation of cytoadherence by cytokinesQ33617104
Identification of a Plasmodium falciparum intercellular adhesion molecule-1 binding domain: a parasite adhesion trait implicated in cerebral malariaQ33890328
Antibody recognition of Plasmodium falciparum erythrocyte surface antigens in Kenya: evidence for rare and prevalent variants.Q34000292
Antibodies to variant antigens on the surfaces of infected erythrocytes are associated with protection from malaria in Ghanaian children.Q34007707
Immunization of Aotus monkeys with a functional domain of the Plasmodium falciparum variant antigen induces protection against a lethal parasite lineQ34020876
Antigenic variation at the infected red cell surface in malaria.Q34360835
Levels of plasma immunoglobulin G with specificity against the cysteine-rich interdomain regions of a semiconserved Plasmodium falciparum erythrocyte membrane protein 1, VAR4, predict protection against malarial anemia and febrile episodesQ34601747
Lack of gender-specific antibody recognition of products from domains of a var gene implicated in pregnancy-associated Plasmodium falciparum malariaQ35106301
Limited cross-reactivity among domains of the Plasmodium falciparum clone 3D7 erythrocyte membrane protein 1 familyQ35220304
Malaria immunity in infants: a special case of a general phenomenon?Q35640581
Association of severe noncerebral Plasmodium falciparum malaria in Brazil with expressed PfEMP1 DBL1 alpha sequences lacking cysteine residuesQ36087903
Plasmodium falciparum associated with severe childhood malaria preferentially expresses PfEMP1 encoded by group A var genesQ36399515
Parasite antigens on the infected red cell surface are targets for naturally acquired immunity to malaria.Q37331646
Plasmodium falciparum erythrocyte membrane protein 1 is a parasitized erythrocyte receptor for adherence to CD36, thrombospondin, and intercellular adhesion molecule 1.Q37659330
Multiple var gene transcripts are expressed in Plasmodium falciparum infected erythrocytes selected for adhesion.Q38300351
Relation between severe malaria morbidity in children and level of Plasmodium falciparum transmission in AfricaQ39115032
Plasmodium falciparum infections are associated with agglutinating antibodies to parasite-infected erythrocyte surface antigens among healthy Kenyan childrenQ39123150
Low antibody responses to variant surface antigens of Plasmodium falciparum are associated with severe malaria and increased susceptibility to malaria attacks in Gabonese children.Q39515251
Malaria-induced acquisition of antibodies to plasmodium falciparum variant surface antigensQ39655161
Plasmodium falciparum rosetting is associated with malaria severity in KenyaQ39822248
Expression of var genes located within polymorphic subtelomeric domains of Plasmodium falciparum chromosomes.Q40022566
Criteria for diagnosing clinical malaria among a semi-immune population exposed to intense and perennial transmissionQ40821519
Human cerebral malaria: association with erythrocyte rosetting and lack of anti-rosetting antibodiesQ41175606
Antibodies to blood stage antigens of Plasmodium falciparum in rural Gambians and their relation to protection against infectionQ44147641
Testing vaccines in human experimental malaria: statistical analysis of parasitemia measured by a quantitative real-time polymerase chain reactionQ44161485
In vitro selection of Plasmodium falciparum 3D7 for expression of variant surface antigens associated with severe malaria in African childrenQ44691470
CD36 peptides that block cytoadherence define the CD36 binding region for Plasmodium falciparum-infected erythrocytes.Q44951127
Antibodies to variable Plasmodium falciparum-infected erythrocyte surface antigens are associated with protection from novel malaria infectionsQ46184700
Identification of a conserved Plasmodium falciparum var gene implicated in malaria in pregnancyQ46586152
Plasmodium falciparum-infected erythrocytes: agglutination by diverse Kenyan plasma is associated with severe disease and young host age.Q46809348
Developmental selection of var gene expression in Plasmodium falciparumQ47741507
A study of var gene transcription in vitro using universal var gene primersQ47857241
Plasmodium falciparum variant surface antigen expression varies between isolates causing severe and nonsevere malaria and is modified by acquired immunityQ47901577
Expression of Plasmodium falciparum-infected erythrocyte membrane protein from cerebral malaria patients.Q47921891
Evidence for the importance of genetic structuring to the structural and functional specialization of the Plasmodium falciparum var gene familyQ47971150
Protection against clinical malaria by heterologous immunoglobulin G antibodies against malaria-infected erythrocyte variant surface antigens requires interaction with asymptomatic infectionsQ47997112
A var gene promoter controls allelic exclusion of virulence genes in Plasmodium falciparum malariaQ48021609
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectmalariaQ12156
Plasmodium falciparumQ311383
membrane proteinQ423042
P304page(s)2415-2420
P577publication date2007-02-05
P1433published inInfection and ImmunityQ6029193
P1476titleImmunoglobulin G antibody reactivity to a group A Plasmodium falciparum erythrocyte membrane protein 1 and protection from P. falciparum malaria
P478volume75

Reverse relations

cites work (P2860)
Q33340826A method for visualizing surface-exposed and internal PfEMP1 adhesion antigens in Plasmodium falciparum infected erythrocytes
Q34147732A plasma survey using 38 PfEMP1 domains reveals frequent recognition of the Plasmodium falciparum antigen VAR2CSA among young Tanzanian children
Q36810422ARAM: an automated image analysis software to determine rosetting parameters and parasitaemia in Plasmodium samples
Q24651173Acquired immunity to malaria
Q41813370Acquisition of naturally occurring antibody responses to recombinant protein domains of Plasmodium falciparum erythrocyte membrane protein 1.
Q33813188Allelic diversity of the Plasmodium falciparum erythrocyte membrane protein 1 entails variant-specific red cell surface epitopes
Q36689554Analysis of antibody induction upon immunization with distinct NTS-DBL1α-domains of PfEMP1 from rosetting Plasmodium falciparum parasites
Q34103586Antibodies against PfEMP1, RIFIN, MSP3 and GLURP are acquired during controlled Plasmodium falciparum malaria infections in naïve volunteers
Q38625368Antigenic Variation in Plasmodium falciparum
Q24672872Antigenic variation in Plasmodium falciparum: gene organization and regulation of the var multigene family
Q35865612Changes in var gene mRNA levels during erythrocytic development in two phenotypically distinct Plasmodium falciparum parasites
Q64115691Comprehensive analysis of Fc-mediated IgM binding to the Plasmodium falciparum erythrocyte membrane protein 1 family in three parasite clones
Q91820560Comprehensive analysis of antibody responses to Plasmodium falciparum erythrocyte membrane protein 1 domains
Q36009883Differences in PfEMP1s recognized by antibodies from patients with uncomplicated or severe malaria
Q36124623Evidence for in vitro and in vivo expression of the conserved VAR3 (type 3) plasmodium falciparum erythrocyte membrane protein 1.
Q34290645Hierarchical, domain type-specific acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 in Tanzanian children
Q33432676High throughput functional assays of the variant antigen PfEMP1 reveal a single domain in the 3D7 Plasmodium falciparum genome that binds ICAM1 with high affinity and is targeted by naturally acquired neutralizing antibodies
Q36071842Mapping the Binding Site of a Cross-Reactive Plasmodium falciparum PfEMP1 Monoclonal Antibody Inhibitory of ICAM-1 Binding.
Q44383434PfEMP1 as a target of human immunity and a vaccine candidate against malaria
Q33700519Plasmodium falciparum erythrocyte membrane protein 1 diversity in seven genomes--divide and conquer
Q34853037Plasmodium falciparum expressing domain cassette 5 type PfEMP1 (DC5-PfEMP1) bind PECAM1.
Q36888526Serological Conservation of Parasite-Infected Erythrocytes Predicts Plasmodium falciparum Erythrocyte Membrane Protein 1 Gene Expression but Not Severity of Childhood Malaria
Q34161839Surface antigens of Plasmodium falciparum-infected erythrocytes as immune targets and malaria vaccine candidates
Q27313623Surface co-expression of two different PfEMP1 antigens on single plasmodium falciparum-infected erythrocytes facilitates binding to ICAM1 and PECAM1
Q34221833The humoral response to Plasmodium falciparum VarO rosetting variant and its association with protection against malaria in Beninese children
Q33846617The kinetics of antibody binding to Plasmodium falciparum VAR2CSA PfEMP1 antigen and modelling of PfEMP1 antigen packing on the membrane knobs
Q28070246The role of PfEMP1 as targets of naturally acquired immunity to childhood malaria: prospects for a vaccine

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