Antibodies against PfEMP1, RIFIN, MSP3 and GLURP are acquired during controlled Plasmodium falciparum malaria infections in naïve volunteers

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Antibodies against PfEMP1, RIFIN, MSP3 and GLURP are acquired during controlled Plasmodium falciparum malaria infections in naïve volunteers is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2011PLoSO...629025T
P356DOI10.1371/JOURNAL.PONE.0029025
P932PMC publication ID3236238
P698PubMed publication ID22174947
P5875ResearchGate publication ID51884905

P50authorThor G. TheanderQ54802168
Christian W. WangQ55182133
Robert W SauerweinQ60043950
Thomas LavstsenQ80377133
Cornelus C HermsenQ114367861
Louise TurnerQ43240630
P2093author name stringSteven B Mwakalinga
P2860cites workExpression of Plasmodium falciparum erythrocyte membrane protein 1 in experimentally infected humansQ24804115
Sub-grouping of Plasmodium falciparum 3D7 var genes based on sequence analysis of coding and non-coding regionsQ24804747
Plasmodium falciparum variant surface antigen expression patterns during malariaQ24811060
Mutually exclusive expression of virulence genes by malaria parasites is regulated independently of antigen productionQ25257163
Surface co-expression of two different PfEMP1 antigens on single plasmodium falciparum-infected erythrocytes facilitates binding to ICAM1 and PECAM1Q27313623
Primary structure and localization of a conserved immunogenicPlasmodium falciparum glutamate rich protein (GLURP) expressed in both the preerythrocytic and erythrocytic stages of the vertebrate life cycleQ27974520
Immunity to non-cerebral severe malaria is acquired after one or two infectionsQ28139257
Transient cross-reactive immune responses can orchestrate antigenic variation in malariaQ28264776
A semi-automated multiplex high-throughput assay for measuring IgG antibodies against Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) domains in small volumes of plasmaQ28384693
The large diverse gene family var encodes proteins involved in cytoadherence and antigenic variation of plasmodium falciparum-infected erythrocytesQ29393314
Cloning the P. falciparum gene encoding PfEMP1, a malarial variant antigen and adherence receptor on the surface of parasitized human erythrocytesQ29618254
Switches in expression of Plasmodium falciparum var genes correlate with changes in antigenic and cytoadherent phenotypes of infected erythrocytesQ29618991
Antigens induced on erythrocytes by P. falciparum: expression of diverse and conserved determinantsQ47886673
Preferential transcription of conserved rif genes in two phenotypically distinct Plasmodium falciparum parasite linesQ47893123
Plasmodium falciparum variant surface antigen expression varies between isolates causing severe and nonsevere malaria and is modified by acquired immunityQ47901577
The Plasmodium falciparum var gene transcription strategy at the onset of blood stage infection in a human volunteerQ47909162
Evidence for the importance of genetic structuring to the structural and functional specialization of the Plasmodium falciparum var gene familyQ47971150
A var gene promoter controls allelic exclusion of virulence genes in Plasmodium falciparum malariaQ48021609
A Plasmodium falciparum GLURP-MSP3 chimeric protein; expression in Lactococcus lactis, immunogenicity and induction of biologically active antibodiesQ33198902
Clinical outcome of experimental human malaria induced by Plasmodium falciparum-infected mosquitoes.Q33365414
Absence of erythrocyte sequestration and lack of multicopy gene family expression in Plasmodium falciparum from a splenectomized malaria patientQ33510341
Several domains from VAR2CSA can induce Plasmodium falciparum adhesion-blocking antibodiesQ33634689
Plasmodium falciparum erythrocyte membrane protein 1 diversity in seven genomes--divide and conquerQ33700519
Identification of an erythrocyte binding peptide from the erythrocyte binding antigen, EBA-175, which blocks parasite multiplication and induces peptide-blocking antibodiesQ33761565
Antibody recognition of Plasmodium falciparum erythrocyte surface antigens in Kenya: evidence for rare and prevalent variants.Q34000292
Selection of glutamate-rich protein long synthetic peptides for vaccine development: antigenicity and relationship with clinical protection and immunogenicityQ34008755
Hierarchical, domain type-specific acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 in Tanzanian childrenQ34290645
A multiplex assay for the simultaneous detection of antibodies against 15 Plasmodium falciparum and Anopheles gambiae saliva antigensQ34351117
Evidence for the involvement of VAR2CSA in pregnancy-associated malariaQ34364093
Levels of plasma immunoglobulin G with specificity against the cysteine-rich interdomain regions of a semiconserved Plasmodium falciparum erythrocyte membrane protein 1, VAR4, predict protection against malarial anemia and febrile episodesQ34601747
Differential expression of var gene groups is associated with morbidity caused by Plasmodium falciparum infection in Tanzanian childrenQ34721291
Limited cross-reactivity among domains of the Plasmodium falciparum clone 3D7 erythrocyte membrane protein 1 familyQ35220304
Antigenicity and immunogenicity of recombinant glutamate-rich protein of Plasmodium falciparum expressed in Escherichia coliQ35223977
Immunoglobulin G antibody reactivity to a group A Plasmodium falciparum erythrocyte membrane protein 1 and protection from P. falciparum malariaQ35783951
Antibodies elicited in adults by a primary Plasmodium falciparum blood-stage infection recognize different epitopes compared with immune individualsQ35901099
Plasmodium falciparum associated with severe childhood malaria preferentially expresses PfEMP1 encoded by group A var genesQ36399515
Induction of adhesion-inhibitory antibodies against placental Plasmodium falciparum parasites by using single domains of VAR2CSA.Q37204480
Parasite antigens on the infected red cell surface are targets for naturally acquired immunity to malaria.Q37331646
Naturally acquired immunity to Plasmodium falciparumQ37778937
Recognition of variant Rifin antigens by human antibodies induced during natural Plasmodium falciparum infectionsQ38854883
Analysis of Plasmodium falciparum var genes expressed in children from Papua New GuineaQ38998322
Antigenic cross-reactivity between different alleles of the Plasmodium falciparum merozoite surface protein 2.Q39001696
The primary antibody response of malaria patients to Plasmodium falciparum sexual stage antigens which are potential transmission blocking vaccine candidatesQ39324954
Long-term protection against malaria after experimental sporozoite inoculation: an open-label follow-up studyQ41932967
Protection against a malaria challenge by sporozoite inoculationQ41937865
Baculovirus expression of erythrovirus V9 capsids and screening by ELISA: serologic cross-reactivity with erythrovirus B19.Q42052491
stevor and rif are Plasmodium falciparum multicopy gene families which potentially encode variant antigensQ42689345
Safety and immunogenicity of the Plasmodium falciparum merozoite surface protein-3 long synthetic peptide (MSP3-LSP) malaria vaccine in healthy, semi-immune adult males in Burkina Faso, West AfricaQ43932881
Detection of Plasmodium falciparum malaria parasites in vivo by real-time quantitative PCR.Q44146886
Testing vaccines in human experimental malaria: statistical analysis of parasitemia measured by a quantitative real-time polymerase chain reactionQ44161485
Plasmodium falciparum infection causes proinflammatory priming of human TLR responsesQ44400436
Sequential, ordered acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 domainsQ44605152
Antibodies to variable Plasmodium falciparum-infected erythrocyte surface antigens are associated with protection from novel malaria infectionsQ46184700
Plasmodium falciparum-infected erythrocytes: agglutination by diverse Kenyan plasma is associated with severe disease and young host age.Q46809348
Antibody recognition of heterologous variant surface antigens after a single Plasmodium falciparum infection in previously naive adults.Q47832295
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectmalariaQ12156
antibodyQ79460
Plasmodium falciparumQ311383
Plasmodium falciparum malariaQ18554672
P304page(s)e29025
P577publication date2011-12-12
P1433published inPLOS OneQ564954
P1476titleAntibodies against PfEMP1, RIFIN, MSP3 and GLURP are acquired during controlled Plasmodium falciparum malaria infections in naïve volunteers
P478volume6

Reverse relations

cites work (P2860)
Q49830014Antibodies in children with malaria to PfEMP1, RIFIN and SURFIN expressed at the Plasmodium falciparum parasitized red blood cell surface
Q61447733Antibody Responses to Antigenic Targets of Recent Exposure Are Associated With Low-Density Parasitemia in Controlled Human Infections
Q38625368Antigenic Variation in Plasmodium falciparum
Q34257253Assessment of humoral immune responses to blood-stage malaria antigens following ChAd63-MVA immunization, controlled human malaria infection and natural exposure
Q35568907Asymptomatic Plasmodium falciparum infection in children is associated with increased auto-antibody production, high IL-10 plasma levels and antibodies to merozoite surface protein 3.
Q59330088Characterization of anti-EBA175RIII-V in asymptomatic adults and children living in communities in the Greater Accra Region of Ghana with varying malaria transmission intensities
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Q36531224Expression of a type B RIFIN in Plasmodium falciparum merozoites and gametes
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Q48023074Genetic Diversity of the Plasmodium falciparum Glutamate-Rich Protein R2 Region Before and Twelve Years after Introduction of Artemisinin Combination Therapies among Febrile Children in Nigeria
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Q34636542Genetic polymorphism and amino acid sequence variation in Plasmodium falciparum GLURP R2 repeat region in Assam, India, at an interval of five years
Q37675077Genetic polymorphisms in the glutamate-rich protein of Plasmodium falciparum field isolates from a malaria-endemic area of Brazil
Q44169469Host immune evasion strategies of malaria blood stage parasite
Q35833840IgG antibodies to endothelial protein C receptor-binding cysteine-rich interdomain region domains of Plasmodium falciparum erythrocyte membrane protein 1 are acquired early in life in individuals exposed to malaria
Q38728601Immune activation and induction of memory: lessons learned from controlled human malaria infection with Plasmodium falciparum
Q34276755Plasmodium falciparum erythrocyte membrane protein 1 domain cassettes 8 and 13 are associated with severe malaria in children
Q28550263Quantifying Transmission Investment in Malaria Parasites
Q35998522Sero-epidemiological evaluation of changes in Plasmodium falciparum and Plasmodium vivax transmission patterns over the rainy season in Cambodia
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Q34161839Surface antigens of Plasmodium falciparum-infected erythrocytes as immune targets and malaria vaccine candidates
Q60954894To B or Not to B: Understanding B Cell Responses in the Development of Malaria Infection
Q35926729Trade-offs in antibody repertoires to complex antigens

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