IgG antibodies to endothelial protein C receptor-binding cysteine-rich interdomain region domains of Plasmodium falciparum erythrocyte membrane protein 1 are acquired early in life in individuals exposed to malaria

scientific article published on 26 May 2015

IgG antibodies to endothelial protein C receptor-binding cysteine-rich interdomain region domains of Plasmodium falciparum erythrocyte membrane protein 1 are acquired early in life in individuals exposed to malaria is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/IAI.00271-15
P932PMC publication ID4496620
P698PubMed publication ID26015475

P50authorLouise TurnerQ43240630
Thor G. TheanderQ54802168
Deus S IshengomaQ55175752
Christian W. WangQ55182133
Thomas LavstsenQ80377133
Bruno P MmbandoQ85689358
John LusinguQ90228924
Lasse S VestergaardQ114320005
Pamela MagistradoQ114320963
P2093author name stringDaniel T R Minja
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Surface co-expression of two different PfEMP1 antigens on single plasmodium falciparum-infected erythrocytes facilitates binding to ICAM1 and PECAM1Q27313623
PfSETvs methylation of histone H3K36 represses virulence genes in Plasmodium falciparumQ27976480
Immunity to non-cerebral severe malaria is acquired after one or two infectionsQ28139257
A semi-automated multiplex high-throughput assay for measuring IgG antibodies against Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) domains in small volumes of plasmaQ28384693
Expression of the domain cassette 8 Plasmodium falciparum erythrocyte membrane protein 1 is associated with cerebral malaria in BeninQ28534938
The large diverse gene family var encodes proteins involved in cytoadherence and antigenic variation of plasmodium falciparum-infected erythrocytesQ29393314
Cloning the P. falciparum gene encoding PfEMP1, a malarial variant antigen and adherence receptor on the surface of parasitized human erythrocytesQ29618254
Switches in expression of Plasmodium falciparum var genes correlate with changes in antigenic and cytoadherent phenotypes of infected erythrocytesQ29618991
Plasmodium falciparum erythrocyte membrane protein 1 diversity in seven genomes--divide and conquerQ33700519
Parasite burden and severity of malaria in Tanzanian childrenQ33882158
Antibodies to variant antigens on the surfaces of infected erythrocytes are associated with protection from malaria in Ghanaian children.Q34007707
A progressive declining in the burden of malaria in north-eastern TanzaniaQ34060866
Antibodies against PfEMP1, RIFIN, MSP3 and GLURP are acquired during controlled Plasmodium falciparum malaria infections in naïve volunteersQ34103586
The humoral response to Plasmodium falciparum VarO rosetting variant and its association with protection against malaria in Beninese childrenQ34221833
Induction of strain-transcending antibodies against Group A PfEMP1 surface antigens from virulent malaria parasitesQ34244920
Identification of a strain-specific malarial antigen exposed on the surface of Plasmodium falciparum-infected erythrocytesQ34257729
Plasmodium falciparum erythrocyte membrane protein 1 domain cassettes 8 and 13 are associated with severe malaria in childrenQ34276755
A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cellsQ34276770
Hierarchical, domain type-specific acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 in Tanzanian childrenQ34290645
A novel domain cassette identifies Plasmodium falciparum PfEMP1 proteins binding ICAM-1 and is a target of cross-reactive, adhesion-inhibitory antibodiesQ34315378
Severe malaria is associated with parasite binding to endothelial protein C receptorQ34348881
DC8 and DC13 var genes associated with severe malaria bind avidly to diverse endothelial cellsQ34355453
Evidence for the involvement of VAR2CSA in pregnancy-associated malariaQ34364093
Structural conservation despite huge sequence diversity allows EPCR binding by the PfEMP1 family implicated in severe childhood malariaQ34452432
Levels of plasma immunoglobulin G with specificity against the cysteine-rich interdomain regions of a semiconserved Plasmodium falciparum erythrocyte membrane protein 1, VAR4, predict protection against malarial anemia and febrile episodesQ34601747
Plasmodium falciparum expressing domain cassette 5 type PfEMP1 (DC5-PfEMP1) bind PECAM1.Q34853037
Structural and functional insight into how the Plasmodium falciparum VAR2CSA protein mediates binding to chondroitin sulfate A in placental malaria.Q36078717
Parasite antigens on the infected red cell surface are targets for naturally acquired immunity to malaria.Q37331646
Malaria's deadly grip: cytoadhesion of Plasmodium falciparum-infected erythrocytesQ37333056
Functional and immunological characterization of a Duffy binding-like alpha domain from Plasmodium falciparum erythrocyte membrane protein 1 that mediates rosettingQ37333406
Rosetting Plasmodium falciparum-infected erythrocytes bind to human brain microvascular endothelial cells in vitro, demonstrating a dual adhesion phenotype mediated by distinct P. falciparum erythrocyte membrane protein 1 domains.Q37643887
The epidemiology of febrile malaria episodes in an area of unstable and seasonal transmissionQ39023301
Parasitologic and clinical human response to immunoglobulin administration in falciparum malaria.Q39417737
Human cerebral malaria: association with erythrocyte rosetting and lack of anti-rosetting antibodiesQ41175606
Maternal malaria and parasite adhesionQ41735835
Altitude-dependent and -independent variations in Plasmodium falciparum prevalence in northeastern TanzaniaQ43948019
Antibodies to blood stage antigens of Plasmodium falciparum in rural Gambians and their relation to protection against infectionQ44147641
The Dielmo project: a longitudinal study of natural malaria infection and the mechanisms of protective immunity in a community living in a holoendemic area of SenegalQ44171038
Sequential, ordered acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 domainsQ44605152
Antibodies to variable Plasmodium falciparum-infected erythrocyte surface antigens are associated with protection from novel malaria infectionsQ46184700
A LONGITUDINAL LONGITUDINAL SURVEY OF NATURAL MALARIA INFECTION IN A GROUP OF WEST AFRICAN ADULTS. IQ46758991
Antigens induced on erythrocytes by P. falciparum: expression of diverse and conserved determinantsQ47886673
Plasmodium falciparum variant surface antigen expression varies between isolates causing severe and nonsevere malaria and is modified by acquired immunityQ47901577
The Plasmodium falciparum var gene transcription strategy at the onset of blood stage infection in a human volunteerQ47909162
Widespread functional specialization of Plasmodium falciparum erythrocyte membrane protein 1 family members to bind CD36 analysed across a parasite genomeQ47923917
Gamma-globulin and acquired immunity to human malariaQ47957467
Parasite burden and severity of malaria in Tanzanian children.Q55189478
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectmalariaQ12156
membrane proteinQ423042
endotheliumQ111140
Plasmodium falciparumQ311383
P304page(s)3096-3103
P577publication date2015-05-26
P1433published inInfection and ImmunityQ6029193
P1476titleIgG antibodies to endothelial protein C receptor-binding cysteine-rich interdomain region domains of Plasmodium falciparum erythrocyte membrane protein 1 are acquired early in life in individuals exposed to malaria
P478volume83

Reverse relations

cites work (P2860)
Q91900053Acquisition of IGG to ICAM-1-Binding DBLΒ Domains in the plasmodium falciparum erythrocyte membrane protein 1 antigen family varies between groups A, B, and C
Q64055939Age-dependent increase in antibodies that inhibit Plasmodium falciparum adhesion to a subset of endothelial receptors
Q56358597Antibodies to Intercellular Adhesion Molecule 1-Binding Plasmodium falciparum Erythrocyte Membrane Protein 1-DBLβ Are Biomarkers of Protective Immunity to Malaria in a Cohort of Young Children from Papua New Guinea
Q58545517Antibody Targets on the Surface of Plasmodium falciparum-Infected Erythrocytes That Are Associated With Immunity to Severe Malaria in Young Children
Q90176965Association of EPCR Polymorphism rs867186-GG With Severity of Human Malaria
Q64360526Associations between IgG reactivity to Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) antigens and Burkitt lymphoma in Ghana and Uganda case-control studies
Q64104479Binding brain better-matching genes and endothelial receptors
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Q38666558The immunological balance between host and parasite in malaria

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