Robert W Sauerwein

researcher ORCID ID = 0000-0002-3163-7202

Robert W Sauerwein is …
instance of (P31):
humanQ5

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P496ORCID iD0000-0002-3163-7202

P735given nameRobertQ4927937
RobertQ4927937
P106occupationresearcherQ1650915
P21sex or gendermaleQ6581097

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author (P50)
Q50092201A Macrophage Colony-Stimulating Factor-Producing γδ T Cell Subset Prevents Malarial Parasitemic Recurrence
Q44164288A consultation on the optimization of controlled human malaria infection by mosquito bite for evaluation of candidate malaria vaccines
Q95336413A double-blind, placebo-controlled phase 1/2a trial of the genetically attenuated malaria vaccine PfSPZ-GA1
Q34753532A genetically attenuated malaria vaccine candidate based on P. falciparum b9/slarp gene-deficient sporozoites
Q30044020A novel multiple-stage antimalarial agent that inhibits protein synthesis
Q35887438A novel plant-produced Pfs25 fusion subunit vaccine induces long-lasting transmission blocking antibody responses
Q35138735A plant-produced Pfs230 vaccine candidate blocks transmission of Plasmodium falciparum
Q35048518A plant-produced Pfs25 VLP malaria vaccine candidate induces persistent transmission blocking antibodies against Plasmodium falciparum in immunized mice
Q50318730A randomized feasibility trial comparing four antimalarial drug regimens to induce Plasmodium falciparum gametocytemia in the controlled human malaria infection model
Q39257146A randomized, placebo-controlled, double-blind trial on sulfadoxine-pyrimethamine alone or combined with artesunate or amodiaquine in uncomplicated malaria
Q27973519A role for apical membrane antigen 1 during invasion of hepatocytes by Plasmodium falciparum sporozoites
Q39492523A scalable assessment of Plasmodium falciparum transmission in the standard membrane-feeding assay, using transgenic parasites expressing green fluorescent protein-luciferase
Q35873837A semi-automated luminescence based standard membrane feeding assay identifies novel small molecules that inhibit transmission of malaria parasites by mosquitoes
Q58707703A sporozoite-based vaccination platform against human malaria
Q36057631A switch in infected erythrocyte deformability at the maturation and blood circulation of Plasmodium falciparum transmission stages
Q33308737A virosomal malaria peptide vaccine elicits a long-lasting sporozoite-inhibitory antibody response in a phase 1a clinical trial
Q43932772Age-dependent distribution of Plasmodium falciparum gametocytes quantified by Pfs25 real-time QT-NASBA in a cross-sectional study in Burkina Faso
Q37243605An inter-laboratory comparison of standard membrane-feeding assays for evaluation of malaria transmission-blocking vaccines
Q95336401An open-label phase 1/2a trial of a genetically modified rodent malaria parasite for immunization against Plasmodium falciparum malaria
Q35683366Analysis of a Multi-component Multi-stage Malaria Vaccine Candidate--Tackling the Cocktail Challenge
Q47915916Analysis of the Plasmodium falciparum proteome by high-accuracy mass spectrometry
Q41500270Anti-CD81 but not anti-SR-BI blocks Plasmodium falciparum liver infection in a humanized mouse model
Q34103586Antibodies against PfEMP1, RIFIN, MSP3 and GLURP are acquired during controlled Plasmodium falciparum malaria infections in naïve volunteers
Q44156482Antibodies to plant-produced Plasmodium falciparum sexual stage protein Pfs25 exhibit transmission blocking activity
Q94670449Antigen-stimulated PBMC transcriptional protective signatures for malaria immunization
Q39337756Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase.
Q90167721Antimalarial pantothenamide metabolites target acetyl-coenzyme A biosynthesis in Plasmodium falciparum
Q44018391Assessing the adequacy of attenuation of genetically modified malaria parasite vaccine candidates
Q38935681Assessing the impact of next-generation rapid diagnostic tests on Plasmodium falciparum malaria elimination strategies
Q40404046Assessment of urinary concentrations of hepcidin provides novel insight into disturbances in iron homeostasis during malarial infection
Q34233691Atovaquone and quinine anti-malarials inhibit ATP binding cassette transporter activity
Q33640267BAFF and BAFF receptor levels correlate with B cell subset activation and redistribution in controlled human malaria infection
Q35914430Bacterium-like particles as multi-epitope delivery platform for Plasmodium berghei circumsporozoite protein induce complete protection against malaria in mice
Q35211003Blood-stage immunity to Plasmodium chabaudi malaria following chemoprophylaxis and sporozoite immunization
Q36004060Breadth of humoral response and antigenic targets of sporozoite-inhibitory antibodies associated with sterile protection induced by controlled human malaria infection
Q112718334CRISPR/Cas9-engineered inducible gametocyte producer lines as a valuable tool for Plasmodium falciparum malaria transmission research
Q44169768Changes in total and differential leukocyte counts during the clinically silent liver phase in a controlled human malaria infection in malaria-naïve Dutch volunteers
Q28554466Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy Modeling
Q40281431Cholesterol contributes to the organization of tetraspanin-enriched microdomains and to CD81-dependent infection by malaria sporozoites
Q43942938Common genotypic polymorphisms in glutathione S-transferases in mild and severe falciparum malaria in Tanzanian children
Q42682357Comparative assessment of An. gambiae and An. stephensi mosquitoes to determine transmission-reducing activity of antibodies against P. falciparum sexual stage antigens
Q28728616Comparison of clinical and parasitological data from controlled human malaria infection trials
Q47831976Complement activation in experimental human malaria infection
Q40105545Concentration of Plasmodium falciparum gametocytes in whole blood samples by magnetic cell sorting enhances parasite infection rates in mosquito feeding assays
Q24814551Concurrence of Plasmodium falciparum dhfr and crt mutations in northern Ghana
Q33750638Construct design, production, and characterization of Plasmodium falciparum 48/45 R0.6C subunit protein produced in Lactococcus lactis as candidate vaccine
Q56362793Controlled Human Malaria Infection with Graded Numbers of NF135.C10- or NF166.C8-Infected Mosquitoes
Q34138437Controlled human malaria infection of Tanzanians by intradermal injection of aseptic, purified, cryopreserved Plasmodium falciparum sporozoites
Q40752958Controlled human malaria infection trials: How tandems of trust and control construct scientific knowledge
Q36523062Controlled human malaria infections by intradermal injection of cryopreserved Plasmodium falciparum sporozoites
Q46787789Controlled human malaria infections using aseptic, purified cryopreserved Plasmodium falciparum sporozoites administered by needle and syringe
Q36670217Correctly folded Pfs48/45 protein of Plasmodium falciparum elicits malaria transmission-blocking immunity in mice
Q51711730Corrigendum: A novel multiple-stage antimalarial agent that inhibits protein synthesis.
Q36483682Cross-species immunity in malaria vaccine development: two, three, or even four for the price of one?
Q38953222Cross-stage immunity for malaria vaccine development
Q34399831Cytotoxic markers associate with protection against malaria in human volunteers immunized with Plasmodium falciparum sporozoites
Q37154138Diagnosis and treatment based on quantitative PCR after controlled human malaria infection
Q35784129Distribution of Plasmodium vivax pvdhfr and pvdhps alleles and their association with sulfadoxine-pyrimethamine treatment outcomes in Indonesia
Q37239022Dynamic histone H3 epigenome marking during the intraerythrocytic cycle of Plasmodium falciparum
Q46151189Early interferon-gamma response against Plasmodium falciparum correlates with interethnic differences in susceptibility to parasitemia between sympatric Fulani and Dogon in Mali
Q44149683Editorial: Malaria investments and activities: it is now! or never?
Q39331198Efficacy and safety of the mosquitocidal drug ivermectin to prevent malaria transmission after treatment: a double-blind, randomized, clinical trial
Q33455349Efficacy of artemisinin-based combination therapy for treatment of persons with uncomplicated Plasmodium falciparum malaria in West Sumba District, East Nusa Tenggara Province, Indonesia, and genotypic profiles of the parasite
Q44164122Efficacy of preerythrocytic and blood-stage malaria vaccines can be assessed in small sporozoite challenge trials in human volunteers
Q37740562Empowering malaria vaccination by drug administration
Q37979164Enhancement of naturally acquired immunity against malaria by drug use.
Q42378882Erratum to: Diagnosis and treatment based on quantitative PCR after controlled human malaria infection
Q33933486Expansion of IgG+ B-cells during mitogen stimulation for memory B-cell ELISpot analysis is influenced by size and composition of the B-cell pool
Q44156054Experimental human challenge infections can accelerate clinical malaria vaccine development
Q40259296Expression of human CD81 differently affects host cell susceptibility to malaria sporozoites depending on the Plasmodium species
Q40159945Expression, Purification and Characterization of GMZ2'.10C, a Complex Disulphide-Bonded Fusion Protein Vaccine Candidate against the Asexual and Sexual Life-Stages of the Malaria-Causing Plasmodium falciparum Parasite
Q56829633Extended malaria parasite clearance time in African children following artemisinin-combination therapy enhances transmission to Anopheles mosquitoes
Q28538917External quality assurance of malaria nucleic acid testing for clinical trials and eradication surveillance
Q90665758Fast and fierce versus slow and smooth: Heterogeneity in immune responses to Plasmodium in the controlled human malaria infection model
Q38927122Gametocytemia and Attractiveness of Plasmodium falciparum-Infected Kenyan Children to Anopheles gambiae Mosquitoes
Q33380159Gene disruption of Plasmodium falciparum p52 results in attenuation of malaria liver stage development in cultured primary human hepatocytes
Q47837113Genetically attenuated P36p-deficient Plasmodium berghei sporozoites confer long-lasting and partial cross-species protection.
Q33922779Genetically attenuated, P36p-deficient malarial sporozoites induce protective immunity and apoptosis of infected liver cells
Q48034345Glutamate-rich protein (GLURP) induces antibodies that inhibit in vitro growth of Plasmodium falciparum in a phase 1 malaria vaccine trial
Q40448134HGF/MET signalling protects Plasmodium-infected host cells from apoptosis.
Q35560599Heterologous Protection against Malaria after Immunization with Plasmodium falciparum Sporozoites
Q34149880Hitting hotspots: spatial targeting of malaria for control and elimination
Q38096725How malaria modulates memory: activation and dysregulation of B cells in Plasmodium infection
Q52715900Human antibodies activate complement against Plasmodium falciparum sporozoites, and are associated with protection against malaria in children.
Q47099112Humoral protection against mosquito bite-transmitted Plasmodium falciparum infection in humanized mice
Q33934212Identification of a major rif transcript common to gametocytes and sporozoites of Plasmodium falciparum
Q37539836Idiopathic acute myocarditis during treatment for controlled human malaria infection: a case report
Q38728601Immune activation and induction of memory: lessons learned from controlled human malaria infection with Plasmodium falciparum
Q35509020Immunization with genetically attenuated P52-deficient Plasmodium berghei sporozoites induces a long-lasting effector memory CD8+ T cell response in the liver
Q35439859Impact of malaria preexposure on antiparasite cellular and humoral immune responses after controlled human malaria infection
Q33826283In Tanzania, hemolysis after a single dose of primaquine coadministered with an artemisinin is not restricted to glucose-6-phosphate dehydrogenase-deficient (G6PD A-) individuals
Q38714971Infectivity of Plasmodium falciparum sporozoites determines emerging parasitemia in infected volunteers.
Q47874621Influenza virosomes: a flu jab for malaria?
Q28742222Inhibitory effect of TNF-α on malaria pre-erythrocytic stage development: influence of host hepatocyte/parasite combinations
Q37623775Integrated transcriptomic and proteomic analyses of P. falciparum gametocytes: molecular insight into sex-specific processes and translational repression
Q37770828Interferon-γ--central mediator of protective immune responses against the pre-erythrocytic and blood stage of malaria
Q34057433KAF156 is an antimalarial clinical candidate with potential for use in prophylaxis, treatment, and prevention of disease transmission
Q58714876Liver Injury in Uncomplicated Malaria is an Overlooked Phenomenon: An Observational Study
Q38100875Liver or blood-stage arrest during malaria sporozoite immunization: the later the better?
Q34260189Long term protection after immunization with P. berghei sporozoites correlates with sustained IFNγ responses of hepatic CD8+ memory T cells
Q41932967Long-term protection against malaria after experimental sporozoite inoculation: an open-label follow-up study
Q40783005MRP1 mediates folate transport and antifolate sensitivity in Plasmodium falciparum
Q33243034Malaria in Wanokaka and Loli sub-districts, West Sumba District, East Nusa Tenggara Province, Indonesia.
Q34730756Malaria infected mosquitoes express enhanced attraction to human odor
Q44168825Malaria transmission after artemether-lumefantrine and dihydroartemisinin-piperaquine: a randomized trial
Q44169388Malaria transmission-blocking antigen, Pfs230, mediates human red blood cell binding to exflagellating male parasites and oocyst production
Q36785468Malaria transmission-blocking vaccines: the bonus of effective malaria control
Q34563555Memory B-cell and antibody responses induced by Plasmodium falciparum sporozoite immunization
Q47965455Memory-like IFN-γ response by NK cells following malaria infection reveals the crucial role of T cells in NK cell activation by P. falciparum
Q46062501Mild increases in serum hepcidin and interleukin-6 concentrations impair iron incorporation in haemoglobin during an experimental human malaria infection
Q54217209Modeling the impact of Plasmodium falciparum sexual stage immunity on the composition and dynamics of the human infectious reservoir for malaria in natural settings.
Q47096821Modelling mosquito infection at natural parasite densities identifies drugs targeting EF2, PI4K or ATP4 as key candidates for interrupting malaria transmission
Q44167789Moderate effect of artemisinin-based combination therapy on transmission of Plasmodium falciparum
Q40042826Modest heterologous protection after Plasmodium falciparum sporozoite immunization: a double-blind randomized controlled clinical trial
Q56379066Mosquito Infectivity and Parasitemia after Controlled Human Malaria Infection
Q37173948Multidrug ATP-binding cassette transporters are essential for hepatic development of Plasmodium sporozoites
Q36547334NF135.C10: a new Plasmodium falciparum clone for controlled human malaria infections
Q43270221Neuroschistosomiasis; an unexpected finding in a Dutch woman
Q42121275New approach for high-throughput screening of drug activity on Plasmodium liver stages
Q41945030No hearing loss associated with the use of artemether-lumefantrine to treat experimental human malaria
Q40484106Novel pantothenate derivatives for anti-malarial chemotherapy
Q38964786Odours of Plasmodium falciparum-infected participants influence mosquito-host interactions
Q48001081On the way to eradicating malaria
Q46808212Persistence of full-length caspase-12 and its relation to malaria in West and Central African populations
Q35149404PfMDR2 and PfMDR5 are dispensable for Plasmodium falciparum asexual parasite multiplication but change in vitro susceptibility to anti-malarial drugs
Q30043157Pfs47, paralog of the male fertility factor Pfs48/45, is a female specific surface protein in Plasmodium falciparum
Q33434412Phase 1/2a study of the malaria vaccine candidate apical membrane antigen-1 (AMA-1) administered in adjuvant system AS01B or AS02A.
Q35095652Phenotyping clinical resistance to chloroquine in Plasmodium vivax in northeastern Papua, Indonesia
Q55362585Plant-produced transmission blocking Plasmodium falciparum Pfs25 subunit and VLP based vaccine candidates.
Q34507085Plasmodium berghei Δp52&p36 parasites develop independent of a parasitophorous vacuole membrane in Huh-7 liver cells
Q35947450Plasmodium falciparum Infection of Human Volunteers Activates Monocytes and CD16+ Dendritic Cells and Induces Upregulation of CD16 and CD1c Expression
Q39257141Plasmodium falciparum dhfr but not dhps mutations associated with sulphadoxine-pyrimethamine treatment failure and gametocyte carriage in northern Ghana
Q24798247Plasmodium falciparum gametocyte carriage in asymptomatic children in western Kenya
Q44400436Plasmodium falciparum infection causes proinflammatory priming of human TLR responses
Q44166267Plasmodium liver load following parenteral sporozoite administration in rodents
Q52880874Plasmodium-associated changes in human odor attract mosquitoes.
Q59807801Pre-clinical evaluation of a -based whole-sporozoite malaria vaccine candidate
Q55283778Predicting the likelihood and intensity of mosquito infection from sex specific Plasmodium falciparum gametocyte density.
Q37361903Progress with Plasmodium falciparum sporozoite (PfSPZ)-based malaria vaccines
Q42643524Proguanil and cycloguanil are organic cation transporter and multidrug and toxin extrusion substrates
Q36835495Protection against malaria after immunization by chloroquine prophylaxis and sporozoites is mediated by preerythrocytic immunity
Q35094826Protection of Malian children from clinical malaria is associated with recognition of multiple antigens
Q39687139Protective Efficacy Induced by Genetically Attenuated Mid-to-Late Liver-Stage Arresting Plasmodium berghei Δmrp2 Parasites
Q40067174Protective immunity differs between routes of administration of attenuated malaria parasites independent of parasite liver load.
Q33381649Proteomic profiling of Plasmodium sporozoite maturation identifies new proteins essential for parasite development and infectivity
Q33235842Rapid onset of transmission-reducing antibodies in javanese migrants exposed to malaria in papua, indonesia
Q43946800Reduction and enhancement of Plasmodium falciparum transmission by endemic human sera
Q28476396Removal of heterologous sequences from Plasmodium falciparum mutants using FLPe-recombinase
Q42127740Residual Plasmodium falciparum parasitemia in Kenyan children after artemisinin-combination therapy is associated with increased transmission to mosquitoes and parasite recurrence
Q39051423Responses to malarial antigens are altered in helminth-infected children
Q36644534Safety, Immunogenicity, and Protective Efficacy of Intradermal Immunization with Aseptic, Purified, Cryopreserved Plasmodium falciparum Sporozoites in Volunteers Under Chloroquine Prophylaxis: A Randomized Controlled Trial
Q38866063Salinomycin and other ionophores as a new class of antimalarial drugs with transmission-blocking activity
Q34657110Scavenger receptor BI boosts hepatocyte permissiveness to Plasmodium infection
Q33507449Seasonal distribution of anti-malarial drug resistance alleles on the island of Sumba, Indonesia
Q43932462Seasonal patterns of Plasmodium falciparum gametocyte prevalence and density in a rural population of Burkina Faso
Q41912660Serious psychiatric symptoms after chloroquine treatment following experimental malaria infection
Q36132026Spatial Patterns of Plasmodium falciparum Clinical Incidence, Asymptomatic Parasite Carriage and Anopheles Density in Two Villages in Mali
Q33960093Sporozoite immunization of human volunteers under chemoprophylaxis induces functional antibodies against pre-erythrocytic stages of Plasmodium falciparum
Q28544964Sporozoite immunization of human volunteers under mefloquine prophylaxis is safe, immunogenic and protective: a double-blind randomized controlled clinical trial
Q57154118Structural basis for recognition of the malaria vaccine candidate Pfs48/45 by a transmission blocking antibody
Q58115505Structural delineation of potent transmission-blocking epitope I on malaria antigen Pfs48/45
Q39320276Structure-activity-based design of a synthetic malaria peptide eliciting sporozoite inhibitory antibodies in a virosomal formulation
Q35314263Studying the effect of chloroquine on sporozoite-induced protection and immune responses in Plasmodium berghei malaria
Q43736591Submicroscopic Plasmodium falciparum gametocyte carriage is common in an area of low and seasonal transmission in Tanzania
Q28474692Submicroscopic gametocytes and the transmission of antifolate-resistant Plasmodium falciparum in Western Kenya
Q27974482Targeting Plasmodium PI(4)K to eliminate malaria
Q44161485Testing vaccines in human experimental malaria: statistical analysis of parasitemia measured by a quantitative real-time polymerase chain reaction
Q28551321The Impact of Hotspot-Targeted Interventions on Malaria Transmission in Rachuonyo South District in the Western Kenyan Highlands: A Cluster-Randomized Controlled Trial
Q57296267The Plasmodium falciparum male gametocyte protein P230p, a paralog of P230, is vital for ookinete formation and mosquito transmission
Q47909162The Plasmodium falciparum var gene transcription strategy at the onset of blood stage infection in a human volunteer
Q36247418The Power of Malaria Vaccine Trials Using Controlled Human Malaria Infection
Q92413853The XN-30 hematology analyzer for rapid sensitive detection of malaria: a diagnostic accuracy study
Q55353878The complement system contributes to functional antibody-mediated responses induced by immunization with Plasmodium falciparum malaria sporozoites.
Q47832907The dog that did not bark: malaria vaccines without antibodies
Q36538665The epidemiology of Plasmodium falciparum gametocytes: weapons of mass dispersion
Q47942237The first malaria vaccine: a significant milestone
Q27973784The human malaria parasite Pfs47 gene mediates evasion of the mosquito immune system
Q26315349The relevance and applicability of oocyst prevalence as a read-out for mosquito feeding assays
Q33553363Three members of the 6-cys protein family of Plasmodium play a role in gamete fertility
Q33375855Thrombocytopenia and release of activated von Willebrand Factor during early Plasmodium falciparum malaria
Q33392346Thrombocytopenia in early malaria is associated with GP1b shedding in absence of systemic platelet activation and consumptive coagulopathy
Q37163165Transcriptomic evidence for modulation of host inflammatory responses during febrile Plasmodium falciparum malaria
Q39690044Transmission of Plasmodium falciparum in urban Yaoundé, Cameroon, is seasonal and age-dependent
Q30042977Two Plasmodium 6-Cys family-related proteins have distinct and critical roles in liver-stage development
Q27973456Type II fatty acid biosynthesis is essential for Plasmodium falciparum sporozoite development in the midgut of Anopheles mosquitoes
Q36564961Variation in susceptibility of African Plasmodium falciparum malaria parasites to TEP1 mediated killing in Anopheles gambiae mosquitoes
Q27335248Visualisation and quantitative analysis of the rodent malaria liver stage by real time imaging
Q39399082Vital and dispensable roles of Plasmodium multidrug resistance transporters during blood- and mosquito-stage development
Q92642716Whole-blood transcriptomic signatures induced during immunization by chloroquine prophylaxis and Plasmodium falciparum sporozoites

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