Genome-wide profiling of the C. elegans dsRNAome

scientific article published on 24 March 2015

Genome-wide profiling of the C. elegans dsRNAome is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1261/RNA.048801.114
P932PMC publication ID4408787
P698PubMed publication ID25805852
P5875ResearchGate publication ID274089560

P2093author name stringBrenda L Bass
W Evan Johnson
Changjin Hong
David A Nix
P Joseph Aruscavage
Joseph M Whipple
Osama A Youssef
P2860cites workViennaRNA Package 2.0Q24053233
Mammalian Staufen1 recruits Upf1 to specific mRNA 3'UTRs so as to elicit mRNA decayQ24293099
RDE-4 preferentially binds long dsRNA and its dimerization is necessary for cleavage of dsRNA to siRNA.Q24543937
A conserved double-stranded RNA-binding domainQ24563195
ADAR1 RNA deaminase limits short interfering RNA efficacy in mammalian cellsQ24598067
DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88Q24621930
Cell stress and translational inhibitors transiently increase the abundance of mammalian SINE transcriptsQ24629021
Specificity of ADAR-mediated RNA editing in newly identified targetsQ24652694
RNA editing by adenosine deaminases that act on RNAQ24679593
Widespread A-to-I RNA editing of Alu-containing mRNAs in the human transcriptomeQ24806860
Trans-splicing and operons in C. elegansQ27014759
Genome sequence of the nematode C. elegans: a platform for investigating biologyQ27860527
Pathogen recognition and innate immunityQ27861084
The fate of dsRNA in the nucleus: a p54(nrb)-containing complex mediates the nuclear retention of promiscuously A-to-I edited RNAsQ28214585
Editing independent effects of ADARs on the miRNA/siRNA pathwaysQ28256753
The GNUMAP algorithm: unbiased probabilistic mapping of oligonucleotides from next-generation sequencingQ28262682
Functions and regulation of RNA editing by ADAR deaminasesQ28274610
Integrative analysis of the Caenorhabditis elegans genome by the modENCODE projectQ28301622
Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasisQ28510028
TLR-independent and P2X7-dependent signaling mediate Alu RNA-induced NLRP3 inflammasome activation in geographic atrophyQ28590969
ANNOVAR: functional annotation of genetic variants from high-throughput sequencing dataQ29547161
BEDTools: a flexible suite of utilities for comparing genomic featuresQ29547332
Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclassesQ29547647
lncRNAs transactivate STAU1-mediated mRNA decay by duplexing with 3' UTRs via Alu elementsQ29617832
Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genesQ29618442
Systematic identification of abundant A-to-I editing sites in the human transcriptomeQ29619584
Probabilistic alignment leads to improved accuracy and read coverage for bisulfite sequencing dataQ30699150
Widespread RNA editing of embedded alu elements in the human transcriptomeQ31108738
A survey of RNA editing in human brainQ31127917
PKR is activated by cellular dsRNAs during mitosis and acts as a mitotic regulatorQ33789589
Dicer's helicase domain is required for accumulation of some, but not all, C. elegans endogenous siRNAs.Q33799115
RNA hairpins in noncoding regions of human brain and Caenorhabditis elegans mRNA are edited by adenosine deaminases that act on RNA.Q34030336
The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-box helicase to direct RNAi in C. elegansQ34137901
Selection for short introns in highly expressed genesQ34140547
Conserved function of lincRNAs in vertebrate embryonic development despite rapid sequence evolutionQ34242790
Identifying RNA editing sites using RNA sequencing data aloneQ34537341
Broad chromosomal domains of histone modification patterns in C. elegansQ34548272
Intron size correlates positively with recombination rate in Caenorhabditis elegansQ34644075
Pausing of reverse transcriptase on retroviral RNA templates is influenced by secondary structures both 5' and 3' of the catalytic siteQ34671582
DICER1 deficit induces Alu RNA toxicity in age-related macular degenerationQ34796058
UNAFold: software for nucleic acid folding and hybridizationQ34810481
Evaluation of alignment algorithms for discovery and identification of pathogens using RNA-SeqQ35034904
Predicting sites of ADAR editing in double-stranded RNA.Q35039886
Profiling the RNA editomes of wild-type C. elegans and ADAR mutantsQ35049409
RNA editing level in the mouse is determined by the genomic repeat repertoireQ35057501
Competition between ADAR and RNAi pathways for an extensive class of RNA targetsQ35301426
Monoclonal antibodies to double-stranded RNA as probes of RNA structure in crude nucleic acid extractsQ35766226
Staufen1 regulates diverse classes of mammalian transcriptsQ35837048
Genes misregulated in C. elegans deficient in Dicer, RDE-4, or RDE-1 are enriched for innate immunity genesQ35847224
The RNA-editing enzyme ADAR1 controls innate immune responses to RNA.Q35973393
Adenosine deaminases that act on RNA induce reproducible changes in abundance and sequence of embryonic miRNAsQ36130858
Effects of ADARs on small RNA processing pathways in C. elegansQ36130861
Inverted Alu dsRNA structures do not affect localization but can alter translation efficiency of human mRNAs independent of RNA editingQ36280659
piRNAs can trigger a multigenerational epigenetic memory in the germline of C. elegansQ36298021
A nuclear Argonaute promotes multigenerational epigenetic inheritance and germline immortalityQ36433534
Long noncoding RNAs in C. elegansQ36446242
Transcriptome-wide identification of A > I RNA editing sites by inosine specific cleavageQ36526566
RNA targets and specificity of Staufen, a double-stranded RNA-binding protein in Caenorhabditis elegansQ36562027
The evolution of sex: empirical insights into the roles of epistasis and driftQ36710753
A starvation-induced noncoding RNA modulates expression of Dicer-regulated genesQ36844155
C. elegans and H. sapiens mRNAs with edited 3' UTRs are present on polysomesQ36909674
Long RNA hairpins that contain inosine are present in Caenorhabditis elegans poly(A)+ RNAQ37195281
Analysis of the constancy of DNA sequences during development and evolution of the nematode Caenorhabditis elegansQ37321090
Amplification of siRNA in Caenorhabditis elegans generates a transgenerational sequence-targeted histone H3 lysine 9 methylation footprintQ37359550
Requirement for the ERI/DICER complex in endogenous RNA interference and sperm development in Caenorhabditis elegansQ37454582
lincRNAs: genomics, evolution, and mechanismsQ37584905
A-to-I RNA editing occurs at over a hundred million genomic sites, located in a majority of human genesQ37614931
mRNA-mRNA duplexes that autoelicit Staufen1-mediated mRNA decayQ37626651
Preferential selection of adenosines for modification by double-stranded RNA adenosine deaminase.Q37639248
The dsRBP and inactive editor ADR-1 utilizes dsRNA binding to regulate A-to-I RNA editing across the C. elegans transcriptomeQ37649414
RNA editing regulates transposon-mediated heterochromatic gene silencingQ37712036
Biology and Mechanisms of Short RNAs in Caenorhabditis elegansQ38124459
Determination of preferential binding sites for anti-dsRNA antibodies on double-stranded RNA by scanning force microscopyQ42053304
A-to-I editing of microRNAs in the mammalian brain increases during development.Q42256991
A spatial and temporal map of C. elegans gene expressionQ42588671
Comparative analysis of algorithms for next-generation sequencing read alignmentQ42613622
ADARs have effects beyond RNA editingQ43233413
Detection of virus infection in plants and differentiation between coexisting viruses by monoclonal antibodies to double-stranded RNA.Q45780510
Direct evidence of a role for heterochromatin in meiotic chromosome segregationQ46381949
Detection of inosine in messenger RNA by inosine-specific cleavage.Q48657666
Global analysis of RNA secondary structure in two metazoans.Q52740984
Transposon silencing in the Caenorhabditis elegans germ line by natural RNAiQ59093938
Centric heterochromatin and the efficiency of achiasmate disjunction in Drosophila female meiosisQ71134588
Double-stranded RNA adenosine deaminases ADAR1 and ADAR2 have overlapping specificitiesQ73102498
P4510describes a project that usesImageQuantQ112270642
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectCaenorhabditis elegansQ91703
RNA sequencingQ2542347
P304page(s)786-800
P577publication date2015-03-24
P1433published inRNAQ7277164
P1476titleGenome-wide profiling of the C. elegans dsRNAome
P478volume21

Reverse relations

cites work (P2860)
Q60956829A-to-I RNA Editing Affects lncRNAs Expression after Heat Shock
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Q42284536Massive A-to-I RNA editing is common across the Metazoa and correlates with dsRNA abundance
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Q50661397Trade-off between Transcriptome Plasticity and Genome Evolution in Cephalopods.
Q36812716Trans and cis factors affecting A-to-I RNA editing efficiency of a noncoding editing target in C. elegans

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