Cholic acid induces a Cftr dependent biliary secretion and liver growth response in mice

scientific article published on 13 February 2015

Cholic acid induces a Cftr dependent biliary secretion and liver growth response in mice is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2015PLoSO..1017599B
P356DOI10.1371/JOURNAL.PONE.0117599
P8608Fatcat IDrelease_ptfxowaaxne5ffa4gqab4obbze
P932PMC publication ID4334531
P698PubMed publication ID25680200
P5875ResearchGate publication ID273953345

P50authorHenkjan J VerkadeQ99400886
Frank A J A BodewesQ114525914
P2093author name stringHugo R de Jonge
Annette S H Gouw
Willemien de Vries
Marcel J Bijvelds
Juul F W Baller
P2860cites workThe phosphatidylethanolamine N-methyltransferase pathway is quantitatively not essential for biliary phosphatidylcholine secretionQ80535952
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Effects of Ursodeoxycholate and cholate feeding on liver disease in FVB mice with a disrupted mdr2 P-glycoprotein gene.Q42555482
Defects in gallbladder emptying and bile Acid homeostasis in mice with cystic fibrosis transmembrane conductance regulator deficiencies.Q43008641
Regulation of cholangiocyte secretionQ44165090
Fat absorption in cystic fibrosis mice is impeded by defective lipolysis and post-lipolytic eventsQ45140576
Localization of the cystic fibrosis transmembrane conductance regulator in human bile duct epithelial cellsQ45866124
Production of a severe cystic fibrosis mutation in mice by gene targetingQ45868497
Identification of fibroblast growth factor 15 as a novel mediator of liver regeneration and its application in the prevention of post-resection liver failure in miceQ45884139
Human hepatic mitochondria generate reactive oxygen species and undergo the permeability transition in response to hydrophobic bile acidsQ46628330
Eradication of small intestinal bacterial overgrowth in the cystic fibrosis mouse reduces mucus accumulationQ46872811
Ursodeoxycholate modulates bile flow and bile salt pool independently from the cystic fibrosis transmembrane regulator (Cftr) in miceQ48190174
The role of bile salt composition in liver pathology of mdr2 (-/-) mice: differences between males and females.Q50956249
Regulation of bile acid synthesis. III. Correlation between biliary bile salt hydrophobicity index and the activities of enzymes regulating cholesterol and bile acid synthesis in the ratQ69701876
Natural history of liver disease in cystic fibrosisQ73114499
Cytotoxicity of bile salts against biliary epithelium: a study in isolated bile ductule fragments and isolated perfused rat liverQ73491970
Cystic fibrosis-associated liver disease: a population-based studyQ80517955
Promotion of liver regeneration/repair by farnesoid X receptor in both liver and intestine in miceQ24626582
A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATIONQ25939000
A simple and sensitive assay of total serum bile acidsQ28333896
Enterohepatic circulation of bile salts in farnesoid X receptor-deficient mice: efficient intestinal bile salt absorption in the absence of ileal bile acid-binding proteinQ28593082
FGF19 regulates cell proliferation, glucose and bile acid metabolism via FGFR4-dependent and independent pathwaysQ28741802
Identification of the cystic fibrosis gene: genetic analysisQ29614402
A single centre experience of liver disease in adults with cystic fibrosis 1995-2006.Q33377573
Pathophysiological preconditions promoting mixed "black" pigment plus cholesterol gallstones in a DeltaF508 mouse model of cystic fibrosisQ33994808
Cholangiocyte biology and cystic fibrosis liver diseaseQ34464126
Characteristic multiorgan pathology of cystic fibrosis in a long-living cystic fibrosis transmembrane regulator knockout murine modelQ35097413
Dose-response of five bile acids on serum and liver bile Acid concentrations and hepatotoxicty in miceQ35231059
Loss of CFTR affects biliary epithelium innate immunity and causes TLR4-NF-κB-mediated inflammatory response in miceQ35269164
Impaired mucosal barrier function in the small intestine of the cystic fibrosis mouseQ35281958
Cystic fibrosis: molecular biology and therapeutic implicationsQ35319385
Prevalence of liver disease in cystic fibrosisQ35626850
Regulation of membrane chloride currents in rat bile duct epithelial cellsQ35824120
Mice with homozygous disruption of the mdr2 P-glycoprotein gene. A novel animal model for studies of nonsuppurative inflammatory cholangitis and hepatocarcinogenesisQ35834086
Animal models of cystic fibrosisQ35908456
Effect of antibiotic treatment on fat absorption in mice with cystic fibrosis.Q37206368
FXR: a metabolic regulator and cell protectorQ37282312
Hepatobiliary disease in patients with cystic fibrosisQ37452650
The biliary HCO(3)(-) umbrella: a unifying hypothesis on pathogenetic and therapeutic aspects of fibrosing cholangiopathiesQ37781024
Mouse models of cystic fibrosis: phenotypic analysis and research applicationsQ37887172
Best practice guidance for the diagnosis and management of cystic fibrosis-associated liver diseaseQ37887181
p38 MAPK: a dual role in hepatocyte proliferation through reactive oxygen speciesQ38125809
Hepatobiliary pathology in patients with cystic fibrosisQ38790995
A mouse model for the cystic fibrosis delta F508 mutation.Q40789334
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)e0117599
P577publication date2015-02-13
P1433published inPLOS OneQ564954
P1476titleCholic acid induces a Cftr dependent biliary secretion and liver growth response in mice
P478volume10

Reverse relations

cites work (P2860)
Q97905953Early pathogenesis of cystic fibrosis gallbladder disease in a porcine model
Q39044713Hepatostat: Liver regeneration and normal liver tissue maintenance
Q92985260Hydrophilic bile acids prevent liver damage caused by lack of biliary phospholipid in Mdr2-/- mice
Q93013565Impaired Intestinal Farnesoid X Receptor Signaling in Cystic Fibrosis Mice
Q57118966Paternal cholestasis exacerbates obesity-associated hypertension in male offspring but is prevented by paternal ursodeoxycholic acid treatment
Q91919553Pathophysiology of Cystic Fibrosis Liver Disease: A Channelopathy Leading to Alterations in Innate Immunity and in Microbiota

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