Fat absorption in cystic fibrosis mice is impeded by defective lipolysis and post-lipolytic events

scientific article published on 4 November 2004

Fat absorption in cystic fibrosis mice is impeded by defective lipolysis and post-lipolytic events is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/AJPGI.00295.2004
P698PubMed publication ID15528257

P2093author name stringRick Havinga
Hugo R de Jonge
Henkjan J Verkade
Inez Bronsveld
Maarten Sinaasappel
Marcel J C Bijvelds
P2860cites workcAMP-mediated inhibition of the epithelial brush border Na+/H+ exchanger, NHE3, requires an associated regulatory proteinQ24569613
A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATIONQ25939000
Pancreatic triglyceride lipase deficiency minimally affects dietary fat absorption but dramatically decreases dietary cholesterol absorption in miceQ28504948
A membrane lipid imbalance plays a role in the phenotypic expression of cystic fibrosis in cftr(-/-) miceQ28505262
Down-regulated in adenoma mediates apical Cl-/HCO3- exchange in rabbit, rat, and human duodenumQ28566267
Small-intestinal abnormalities in cystic fibrosis patientsQ34003555
A molecular mechanism for aberrant CFTR-dependent HCO(3)(-) transport in cystic fibrosisQ34206913
Effect of cimetidine on enzyme inactivation, bile acid precipitation, and lipid solubilisation in pancreatic steatorrhoea due to cystic fibrosisQ34527348
Characteristic multiorgan pathology of cystic fibrosis in a long-living cystic fibrosis transmembrane regulator knockout murine modelQ35097413
A fluorimetric and enzymatic method for the estimation of serum total bile acidsQ36622206
Aberrant CFTR-dependent HCO3- transport in mutations associated with cystic fibrosisQ40821697
Modulation of disease severity in cystic fibrosis transmembrane conductance regulator deficient mice by a secondary genetic factorQ41226239
Metabolism of the apolipoprotein B-containing lipoproteinsQ41364938
Identification of transport abnormalities in duodenal mucosa and duodenal enterocytes from patients with cystic fibrosisQ41738688
A functional CFTR protein is required for mouse intestinal cAMP-, cGMP- and Ca(2+)-dependent HCO3- secretion.Q42449164
Fat absorption in germ-free and conventional rats artificially deprived of bile secretionQ43255665
Effects of omeprazole and pirenzepine on enterochromaffin-like cells and parietal cells in rat stomachQ43655000
Omeprazole enhances the efficacy of pancreatin (pancrease) in cystic fibrosisQ43742899
Pancreatic acinar cell dysfunction in CFTR(-/-) mice is associated with impairments in luminal pH and endocytosisQ43770471
cAMP inhibition of murine intestinal Na/H exchange requires CFTR-mediated cell shrinkage of villus epitheliumQ44601450
The DeltaF508 mutation results in loss of CFTR function and mature protein in native human colonQ44709432
Additional disruption of the ClC-2 Cl(-) channel does not exacerbate the cystic fibrosis phenotype of cystic fibrosis transmembrane conductance regulator mouse modelsQ44790624
Acidic duodenal pH alters gene expression in the cystic fibrosis mouse pancreasQ44830083
No indications for altered essential fatty acid metabolism in two murine models for cystic fibrosisQ45091549
Production of a severe cystic fibrosis mutation in mice by gene targetingQ45868497
Bile acid kinetics and biliary lipid composition in cystic fibrosis.Q51580700
Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)-Mediated Residual Chloride Secretion Does Not Protect against Early Chronic Pseudomonas aeruginosa Infection in F508del Homozygous Cystic Fibrosis PatientsQ51644964
Postprandial chylomicron formation and fat absorption in multidrug resistance gene 2 P-glycoprotein-deficient mice.Q52537428
P433issue4
P921main subjectcystic fibrosisQ178194
P304page(s)G646-53
P577publication date2004-11-04
P1433published inAmerican Journal of Physiology - Gastrointestinal and Liver PhysiologyQ15765756
P1476titleFat absorption in cystic fibrosis mice is impeded by defective lipolysis and post-lipolytic events
P478volume288

Reverse relations

cites work (P2860)
Q46613366Activation of CFTR by ASBT-mediated bile salt absorption
Q37175561Altered de novo lipogenesis contributes to low adipose stores in cystic fibrosis mice
Q37596433Bioelectric characterization of epithelia from neonatal CFTR knockout ferrets
Q33576842CFTR depletion results in changes in fatty acid composition and promotes lipogenesis in intestinal Caco 2/15 cells
Q35561131Cholic acid induces a Cftr dependent biliary secretion and liver growth response in mice
Q35216745Cystic fibrosis growth retardation is not correlated with loss of Cftr in the intestinal epithelium
Q43008641Defects in gallbladder emptying and bile Acid homeostasis in mice with cystic fibrosis transmembrane conductance regulator deficiencies.
Q34090196Disease phenotype of a ferret CFTR-knockout model of cystic fibrosis.
Q37206368Effect of antibiotic treatment on fat absorption in mice with cystic fibrosis.
Q37130749Enteric circular muscle dysfunction in the cystic fibrosis mouse small intestine
Q30502773Ezrin-mediated apical integrity is required for intestinal homeostasis
Q35693982Genetic Inhibition Of The Ubiquitin Ligase Rnf5 Attenuates Phenotypes Associated To F508del Cystic Fibrosis Mutation.
Q47406142IGF Binding Protein-3 Treatment Alters Intestinal Cell Proliferation But Not Body Weight of Adult Cystic Fibrosis Transmembrane Conductance Regulator Deficient Mice
Q93013565Impaired Intestinal Farnesoid X Receptor Signaling in Cystic Fibrosis Mice
Q35281958Impaired mucosal barrier function in the small intestine of the cystic fibrosis mouse
Q94563709Improved residual fat malabsorption and growth in children with cystic fibrosis treated with a novel oral structured lipid supplement: A randomized controlled trial
Q47280680Intestinal phenotype of variable-weight cystic fibrosis knockout mice
Q37302555Knockout mouse models for intestinal electrolyte transporters and regulatory PDZ adaptors: new insights into cystic fibrosis, secretory diarrhoea and fructose-induced hypertension.
Q35185218Loss of intestinal GATA4 prevents diet-induced obesity and promotes insulin sensitivity in mice.
Q37887172Mouse models of cystic fibrosis: phenotypic analysis and research applications
Q33994808Pathophysiological preconditions promoting mixed "black" pigment plus cholesterol gallstones in a DeltaF508 mouse model of cystic fibrosis
Q34335468Purinergic regulation of duodenal surface pH and ATP concentration: implications for mucosal defence, lipid uptake and cystic fibrosis
Q92378159Slc26 Family of Anion Transporters in the Gastrointestinal Tract: Expression, Function, Regulation, and Role in Disease
Q83225906Systematic genetic analysis of the MHC region reveals mechanistic underpinnings of HLA type associations with disease
Q37122355The cystic fibrosis intestine
Q43169002The cystic fibrosis transmembrane conductance regulator (Cftr) modulates the timing of puberty in mice
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Q48190174Ursodeoxycholate modulates bile flow and bile salt pool independently from the cystic fibrosis transmembrane regulator (Cftr) in mice

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