| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1037408582 |
| P356 | DOI | 10.1186/S13045-015-0137-1 |
| P932 | PMC publication ID | 4419472 |
| P698 | PubMed publication ID | 25902914 |
| P5875 | ResearchGate publication ID | 275360198 |
| P2093 | author name string | Zhiyu Li | |
| Ting Ni | |||
| Kai Zhao | |||
| Xiaotang Wang | |||
| Na Lu | |||
| Qinglong Guo | |||
| Yuxin Zhou | |||
| Libin Wei | |||
| Chen Qiao | |||
| P2860 | cites work | The lipid phosphatase activity of PTEN is critical for its tumor supressor function | Q22007981 |
| SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress | Q24599420 | ||
| SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress | Q24670578 | ||
| p53, the cellular gatekeeper for growth and division | Q27860990 | ||
| Surfing the p53 network | Q28032484 | ||
| TIGAR, a p53-inducible regulator of glycolysis and apoptosis | Q28118306 | ||
| PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms | Q28181035 | ||
| p53 regulates mitochondrial respiration | Q28242400 | ||
| SIRT3 and cancer: tumor promoter or suppressor? | Q28390097 | ||
| Glycolytic enzymes can modulate cellular life span | Q28508036 | ||
| Targeted inactivation of Mdm2 RING finger E3 ubiquitin ligase activity in the mouse reveals mechanistic insights into p53 regulation | Q28508240 | ||
| The tumor suppressor p53 down-regulates glucose transporters GLUT1 and GLUT4 gene expression | Q28609179 | ||
| Blinded by the Light: The Growing Complexity of p53 | Q29547590 | ||
| Characterization of the murine SIRT3 mitochondrial localization sequence and comparison of mitochondrial enrichment and deacetylase activity of long and short SIRT3 isoforms | Q33807034 | ||
| Oroxylin A improves the sensitivity of HT-29 human colon cancer cells to 5-FU through modulation of the COX-2 signaling pathway. | Q53270194 | ||
| Clinical study of recombinant adenovirus-p53 combined with fractionated stereotactic radiotherapy for hepatocellular carcinoma | Q64375108 | ||
| A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus | Q33944754 | ||
| Regulation and function of the p53 tumor suppressor protein | Q34245385 | ||
| Lipid phosphate phosphatase inhibitors locally amplify lysophosphatidic acid LPA1 receptor signalling in rat brain cryosections without affecting global LPA degradation | Q34300049 | ||
| SIRT1 and p53, effect on cancer, senescence and beyond | Q34341091 | ||
| p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2. | Q34585107 | ||
| A functional p53-responsive intronic promoter is contained within the humanmdm2gene | Q34761984 | ||
| PTEN acetylation modulates its interaction with PDZ domain | Q34817146 | ||
| Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation | Q35089377 | ||
| Inhibition of glycolytic enzymes mediated by pharmacologically activated p53: targeting Warburg effect to fight cancer | Q35842210 | ||
| SIRT3 functions in the nucleus in the control of stress-related gene expression | Q36435193 | ||
| Oroxylin A induces dissociation of hexokinase II from the mitochondria and inhibits glycolysis by SIRT3-mediated deacetylation of cyclophilin D in breast carcinoma | Q36809567 | ||
| Sirtuins: critical regulators at the crossroads between cancer and aging | Q36908428 | ||
| TP53 status and response to chemotherapy in breast cancer | Q37188288 | ||
| PTEN in cancer, metabolism, and aging. | Q37331397 | ||
| Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator. | Q37343700 | ||
| Targeting p53 for enhanced radio- and chemo-sensitivity. | Q37406067 | ||
| The Role of p53 in Metabolic Regulation | Q37903700 | ||
| The fundamental role of the p53 pathway in tumor metabolism and its implication in tumor therapy | Q37981552 | ||
| Two p53-related metabolic regulators, TIGAR and SCO2, contribute to oroxylin A-mediated glucose metabolism in human hepatoma HepG2 cells | Q39161789 | ||
| Oroxylin A reverses multi-drug resistance of human hepatoma BEL7402/5-FU cells via downregulation of P-glycoprotein expression by inhibiting NF-κB signaling pathway. | Q39545301 | ||
| Oroxylin A inhibits angiogenesis through blocking vascular endothelial growth factor-induced KDR/Flk-1 phosphorylation | Q39779218 | ||
| Apoptosis induction of oroxylin A in human cervical cancer HeLa cell line in vitro and in vivo | Q39897020 | ||
| Oroxylin A suppresses invasion through down-regulating the expression of matrix metalloproteinase-2/9 in MDA-MB-435 human breast cancer cells | Q39902850 | ||
| Oroxylin A induces G2/M phase cell-cycle arrest via inhibiting Cdk7-mediated expression of Cdc2/p34 in human gastric carcinoma BGC-823 cells | Q39924269 | ||
| The human SIRT3 protein deacetylase is exclusively mitochondrial | Q40021465 | ||
| Small molecule inhibition of HDM2 leads to p53-mediated cell death in retinoblastoma cells | Q40289368 | ||
| Gambogic acid induces apoptosis and regulates expressions of Bax and Bcl-2 protein in human gastric carcinoma MGC-803 cells | Q40534739 | ||
| Inhibition of p53 degradation by Mdm2 acetylation | Q40580015 | ||
| PTEN reverses MDM2-mediated chemotherapy resistance by interacting with p53 in acute lymphoblastic leukemia cells | Q40626075 | ||
| Wild type p53 can mediate sequence-specific transactivation of an internal promoter within the mdm2 gene. | Q41511192 | ||
| PTEN regulates Mdm2 expression through the P1 promoter | Q44848220 | ||
| Involvement of p53 in oroxylin A-induced apoptosis in cancer cells. | Q45922422 | ||
| Isolation and purification of baicalein, wogonin and oroxylin A from the medicinal plant Scutellaria baicalensis by high-speed counter-current chromatography | Q46532320 | ||
| Sirt3 inhibits hepatocellular carcinoma cell growth through reducing Mdm2-mediated p53 degradation. | Q46668139 | ||
| UCP2-related mitochondrial pathway participates in oroxylin A-induced apoptosis in human colon cancer cells | Q46834583 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P304 | page(s) | 41 | |
| P577 | publication date | 2015-04-23 | |
| P1433 | published in | Journal of Hematology & Oncology | Q15724593 |
| P1476 | title | Oroxylin A promotes PTEN-mediated negative regulation of MDM2 transcription via SIRT3-mediated deacetylation to stabilize p53 and inhibit glycolysis in wt-p53 cancer cells | |
| P478 | volume | 8 |
| Q36022033 | Antiviral Activity of Oroxylin A against Coxsackievirus B3 Alleviates Virus-Induced Acute Pancreatic Damage in Mice |
| Q92304086 | Correction to: Oroxylin A promotes PTEN-mediated negative regulation of MDM2 transcription via SIRT3-mediated deacetylation to stabilize p53 and inhibit glycolysis in wt-p53 cancer cells |
| Q38689132 | Estradiol via estrogen receptor beta influences ROS levels through the transcriptional regulation of SIRT3 in human seminoma TCam-2 cells. |
| Q37615064 | Is p53 Involved in Tissue-Specific Insulin Resistance Formation? |
| Q37117127 | MicroRNA-20a-5p contributes to hepatic glycogen synthesis through targeting p63 to regulate p53 and PTEN expression |
| Q98159126 | Mitochondrial Sirtuin 3: New emerging biological function and therapeutic target |
| Q37086189 | Oroxylin A modulates mitochondrial function and apoptosis in human colon cancer cells by inducing mitochondrial translocation of wild-type p53. |
| Q41084220 | Oroxylin A suppresses the development and growth of colorectal cancer through reprogram of HIF1α-modulated fatty acid metabolism |
| Q38931197 | Overview of Oroxylin A: A Promising Flavonoid Compound |
| Q48365119 | SIRT3 deacetylates and promotes degradation of P53 in PTEN-defective non-small cell lung cancer. |
| Q38993512 | SirT3 and p53 Deacetylation in Aging and Cancer |
| Q37440458 | TIGAR cooperated with glycolysis to inhibit the apoptosis of leukemia cells and associated with poor prognosis in patients with cytogenetically normal acute myeloid leukemia |
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