scholarly article | Q13442814 |
P356 | DOI | 10.1074/JBC.M114.617092 |
P8608 | Fatcat ID | release_mfzzfru4jfef3fdfdz43w4wcym |
P932 | PMC publication ID | 4424341 |
P698 | PubMed publication ID | 25767117 |
P50 | author | Francis Chee Kuan Tan | Q47339778 |
Gavin S. Dawe | Q56065856 | ||
P2093 | author name string | Chao Liu | |
Zhi-Cheng Xiao | |||
P2860 | cites work | Synapse Formation and Function Is Modulated by the Amyloid Precursor Protein | Q22241520 |
Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease | Q24298553 | ||
AnkyrinG. A new ankyrin gene with neural-specific isoforms localized at the axonal initial segment and node of Ranvier | Q24311821 | ||
Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model | Q24603560 | ||
Heterozygosity for a protein truncation mutation of sodium channel SCN8A in a patient with cerebellar atrophy, ataxia, and mental retardation | Q43168798 | ||
Phosphorylation of thr(668) in the cytoplasmic domain of the Alzheimer's disease amyloid precursor protein by stress-activated protein kinase 1b (Jun N-terminal kinase-3). | Q43516562 | ||
Phosphorylation-induced structural changes in the amyloid precursor protein cytoplasmic tail detected by NMR. | Q43556227 | ||
Involvement of c-Jun N-terminal kinase in amyloid precursor protein-mediated neuronal cell death. | Q44299710 | ||
Endocytosis of Receptor Tyrosine Kinases Is Driven by Monoubiquitylation, Not Polyubiquitylation | Q44420471 | ||
Amyloid beta-induced neuronal hyperexcitability triggers progressive epilepsy. | Q46084355 | ||
Sodium channel activity modulates multiple functions in microglia | Q46179678 | ||
Role of axonal NaV1.6 sodium channels in action potential initiation of CA1 pyramidal neurons | Q46466583 | ||
Physiological regulation of the beta-amyloid precursor protein signaling domain by c-Jun N-terminal kinase JNK3 during neuronal differentiation. | Q46535530 | ||
Impaired firing and cell-specific compensation in neurons lacking nav1.6 sodium channels. | Q47850400 | ||
c-Jun phosphorylation in Alzheimer disease | Q48190468 | ||
Formation and maturation of synapses in primary cultures of rat cerebral cortical cells: an electron microscopic study | Q48340777 | ||
Dissociated cortical networks show spontaneously correlated activity patterns during in vitro development | Q48531694 | ||
Altered Subthreshold Sodium Currents and Disrupted Firing Patterns in Purkinje Neurons of Scn8a Mutant Mice | Q48601594 | ||
Persistent Sodium Currents through Brain Sodium Channels Induced by G Protein βγ Subunits | Q48643992 | ||
Resurgent sodium current and action potential formation in dissociated cerebellar Purkinje neurons. | Q48683657 | ||
Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer's disease | Q48920532 | ||
Validation of long-term primary neuronal cultures and network activity through the integration of reversibly bonded microbioreactors and MEA substrates. | Q48939471 | ||
In Vitro Phosphorylation of the Cytoplasmic Domain of the Amyloid Precursor Protein by Glycogen Synthase Kinase-3β | Q56591577 | ||
Polarized distribution of ion channels within microdomains of the axon initial segment | Q79366632 | ||
Sodium channel Na(v)1.6 is localized at nodes of ranvier, dendrites, and synapses | Q24653551 | ||
Direct control of exocytosis by receptor-mediated activation of the heterotrimeric GTPases Gi and G(o) or by the expression of their active G alpha subunits | Q27865299 | ||
De Novo Pathogenic SCN8A Mutation Identified by Whole-Genome Sequencing of a Family Quartet Affected by Infantile Epileptic Encephalopathy and SUDEP | Q28111582 | ||
Nomenclature of voltage-gated sodium channels | Q28141860 | ||
Signal transduction by the JNK group of MAP kinases | Q28142592 | ||
The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase | Q28145635 | ||
Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory | Q28202553 | ||
International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels | Q28289125 | ||
The intrinsic electrophysiological properties of mammalian neurons: insights into central nervous system function | Q28289375 | ||
Modulation of rat cardiac sodium channel by the stimulatory G protein alpha subunit | Q28579766 | ||
Interaction of voltage-gated sodium channel Nav1.6 (SCN8A) with microtubule-associated protein Map1b | Q28587249 | ||
beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity | Q28593175 | ||
Direct observation of individual endogenous protein complexes in situ by proximity ligation | Q29616032 | ||
High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation | Q29616564 | ||
Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation | Q29622825 | ||
The ataxia3 mutation in the N-terminal cytoplasmic domain of sodium channel Na(v)1.6 disrupts intracellular trafficking | Q30487520 | ||
Transsynaptic progression of amyloid-β-induced neuronal dysfunction within the entorhinal-hippocampal network | Q30498362 | ||
Exaggerated emotional behavior in mice heterozygous null for the sodium channel Scn8a (Nav1.6). | Q33888893 | ||
Neuron-specific phosphorylation of Alzheimer's beta-amyloid precursor protein by cyclin-dependent kinase 5. | Q33913155 | ||
Prostaglandin E2 promotes Na1.8 trafficking via its intracellular RRR motif through the protein kinase A pathway | Q34089500 | ||
Sodium channel SCN8A (Nav1.6): properties and de novo mutations in epileptic encephalopathy and intellectual disability | Q34382820 | ||
In vitro phosphorylation of the cytoplasmic domain of the amyloid precursor protein by glycogen synthase kinase-3beta | Q34393147 | ||
Amyloid precursor protein revisited: neuron-specific expression and highly stable nature of soluble derivatives. | Q35709838 | ||
Subunit dependence of Na channel slow inactivation and open channel block in cerebellar neurons | Q35774461 | ||
Allelic mutations of the sodium channel SCN8A reveal multiple cellular and physiological functions | Q35993999 | ||
Amyloid precursor protein at node of Ranvier modulates nodal formation | Q36124650 | ||
JNK signalling: a possible target to prevent neurodegeneration. | Q36855703 | ||
Role of the terminal domains in sodium channel localization. | Q37448824 | ||
Cytosolic Na+ controls and epithelial Na+ channel via the Go guanine nucleotide-binding regulatory protein | Q37464157 | ||
Age-dependent, non-cell-autonomous deposition of amyloid from synthesis of β-amyloid by cells other than excitatory neurons | Q37617388 | ||
Sodium channels and microglial function | Q37943907 | ||
Alzheimer amyloid protein precursor complexes with brain GTP-binding protein G(o) | Q38321052 | ||
Amyloid precursor protein 695 associates with assembled NR2A- and NR2B-containing NMDA receptors to result in the enhancement of their cell surface delivery | Q39790331 | ||
Molecular cloning, distribution and functional analysis of the NA(V)1.6. Voltage-gated sodium channel from human brain | Q40719915 | ||
The amyloid precursor protein interacts with Go heterotrimeric protein within a cell compartment specialized in signal transduction | Q42468094 | ||
APP processing is regulated by cytoplasmic phosphorylation | Q42917696 | ||
The effects of amyloid precursor protein on postsynaptic composition and activity. | Q43009196 | ||
P433 | issue | 19 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 12048-12057 | |
P577 | publication date | 2015-03-12 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Amyloid precursor protein enhances Nav1.6 sodium channel cell surface expression | |
P478 | volume | 290 |
Q47296024 | APP upregulation contributes to retinal ganglion cell degeneration via JNK3. |
Q37529350 | Amyloid precursor protein modulates Nav1.6 sodium channel currents through a Go-coupled JNK pathway |
Q90183474 | Amyloid β-Induced Upregulation of Nav1.6 Underlies Neuronal Hyperactivity in Tg2576 Alzheimer's Disease Mouse Model |
Q89971236 | An alternative mechanism of early nodal clustering and myelination onset in GABAergic neurons of the central nervous system |
Q36665599 | Elevated Neuronal Excitability Due to Modulation of the Voltage-Gated Sodium Channel Nav1.6 by Aβ1-42. |
Q83225902 | Mechanisms of hyperexcitability in Alzheimer's disease hiPSC-derived neurons and cerebral organoids vs isogenic controls |
Q37460683 | Remarkable alterations of Nav1.6 in reactive astrogliosis during epileptogenesis |
Q38403275 | Sodium channel subtypes are differentially localized to pre- and post-synaptic sites in rat hippocampus. |
Q39292465 | The Segregated Expression of Voltage-Gated Potassium and Sodium Channels in Neuronal Membranes: Functional Implications and Regulatory Mechanisms |
Q30835774 | The kinetochore-dependent and -independent formation of the CDC20-MAD2 complex and its functions in HeLa cells |
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