| scholarly article | Q13442814 |
| P50 | author | Masamichi Aikawa | Q80368797 |
| P2093 | author name string | H Nagasawa | |
| J H Leech | |||
| J H McKerrow | |||
| P J Rosenthal | |||
| P2860 | cites work | Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4 | Q25938983 |
| Human malaria parasites in continuous culture | Q28131626 | ||
| Glutathione | Q28261279 | ||
| Synchronization of Plasmodium falciparum Erythrocytic Stages in Culture | Q29547549 | ||
| Biochemistry of Plasmodium (malarial parasites) | Q33624148 | ||
| Antimalarials increase vesicle pH in Plasmodium falciparum | Q36213878 | ||
| Identification of three stage-specific proteinases of Plasmodium falciparum | Q36353862 | ||
| Characterization of globin domains: heme binding to the central exon product | Q36359644 | ||
| High-resolution autoradiography of malarial parasites treated with 3 H-chloroquine | Q36540888 | ||
| The use of electron microscope autoradiography for examining the uptake and degradation of haemoglobin byPlasmodium berghei | Q36559562 | ||
| Acid-vesicle function, intracellular pathogens, and the action of chloroquine against Plasmodium falciparum | Q39663518 | ||
| Intracellular proteases | Q39664942 | ||
| Parasitological review. Plasmodium: the fine structure of malarial parasites | Q39906807 | ||
| Concentration from Continuous Culture of Erythrocytes Infected with Trophozoites and Schizonts of Plasmodium Falciparum * | Q40974465 | ||
| Identification of the acidic compartment of Plasmodium falciparum-infected human erythrocytes as the target of the antimalarial drug chloroquine | Q41584415 | ||
| Plasmodium lophurae: Composition and properties of hemozoin, the malarial pigment | Q41680586 | ||
| Digestion of the host erythrocyte by malaria parasites is the primary target for quinoline-containing antimalarials | Q41915204 | ||
| Characterization of a hemoglobin-degrading, low molecular weight protease from Plasmodium falciparum | Q41915792 | ||
| Effects of chloroquine on the feeding mechanism of the intraerythrocytic human malarial parasite Plasmodium falciparum | Q41918836 | ||
| The sulphur requirements of the erythrocytic from of Plasmodium knowlesi | Q42977260 | ||
| Purification of Plasmodium lophurae cathepsin D and its effects on erythrocyte membrane proteins | Q44031969 | ||
| Malaria Infection ( Plasmodium lophurae ): Changes in Free Amino Acids | Q47969319 | ||
| Intron–exon splice junctions map at protein surfaces | Q59075278 | ||
| Plasmodium falciparum: protease inhibitors and inhibition of erythrocyte invasion | Q68916531 | ||
| E-64 [L-trans-epoxysuccinyl-leucyl-amido(4-guanidino)butane] and related epoxides as inhibitors of cysteine proteinases | Q70236431 | ||
| Peptidases from Plasmodium falciparum cultured in vitro | Q70248890 | ||
| Metabolism of Babesia parasites in vitro. amino acid production by Babesia rodhaini compared to Plasmodium berghei | Q70260592 | ||
| Accumulation of autophagosomes after inhibition of hepatocytic protein degradation by vinblastine, leupeptin or a lysosomotropic amine | Q70272402 | ||
| 59 Inhibitors of lysosomal function | Q70309713 | ||
| Electrophoretic analysis of plasminogen activators in polyacrylamide gels containing sodium dodecyl sulfate and copolymerized substrates | Q70645807 | ||
| Metabolism of leupeptin and its effect on autophagy in the perfused rat liver | Q71109633 | ||
| Free Amino-Acid Production In Vitro by Plasmodium Berghei | Q72230164 | ||
| The effect of leupeptin on intracellular digestion of asialofetuin in rat hepatocytes | Q72638786 | ||
| Dynamic aspects of the nitrogen metabolism of Plasmodium gallinaceum in vivo and in vitro | Q75722496 | ||
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | malaria | Q12156 |
| Plasmodium falciparum | Q311383 | ||
| P304 | page(s) | 1560-1566 | |
| P577 | publication date | 1988-11-01 | |
| P1433 | published in | Journal of Clinical Investigation | Q3186904 |
| P1476 | title | A malarial cysteine proteinase is necessary for hemoglobin degradation by Plasmodium falciparum | |
| P478 | volume | 82 |
| Q40866974 | 4-Aminoquinolines--past, present, and future: a chemical perspective |
| Q37321713 | A 54 kDa cysteine protease purified from the crude extract of Neodiplostomum seoulense adult worms |
| Q38527989 | A distinct member of the aspartic proteinase gene family from the human malaria parasite Plasmodium falciparum |
| Q22061872 | A molecular marker of artemisinin-resistant Plasmodium falciparum malaria |
| Q43923777 | Activity and inhibition of plasmepsin IV, a new aspartic proteinase from the malaria parasite, Plasmodium falciparum |
| Q35091523 | Addressing the malaria drug resistance challenge using flow cytometry to discover new antimalarials |
| Q34005506 | Altered plasmodial surface anion channel activity and in vitro resistance to permeating antimalarial compounds |
| Q36372697 | Amino acid starvation induced by protease inhibition produces differential alterations in redox status and the thiol proteome in organogenesis-stage rat embryos and visceral yolk sacs. |
| Q41925015 | An endoperoxide-based hybrid approach to deliver falcipain inhibitors inside malaria parasites |
| Q33586646 | An overview of chemotherapeutic targets for antimalarial drug discovery |
| Q39478859 | Analysis of antimalarial synergy between bestatin and endoprotease inhibitors using statistical response-surface modelling |
| Q44459212 | Ankyrin peptide blocks falcipain-2-mediated malaria parasite release from red blood cells |
| Q34231399 | Antimalarial activities of novel synthetic cysteine protease inhibitors |
| Q41938383 | Antimalarial activity of thiosemicarbazones and purine derived nitriles. |
| Q34207289 | Antimalarial effects of peptide inhibitors of a Plasmodium falciparum cysteine proteinase |
| Q35125482 | Antimalarial effects of vinyl sulfone cysteine proteinase inhibitors |
| Q41937177 | Antimalarial evaluation of copper(II) nanohybrid solids: inhibition of plasmepsin II, a hemoglobin-degrading malarial aspartic protease from Plasmodium falciparum |
| Q33696222 | Antimalarial synergy of cysteine and aspartic protease inhibitors |
| Q36646501 | Artemisinin activity-based probes identify multiple molecular targets within the asexual stage of the malaria parasites Plasmodium falciparum 3D7. |
| Q22061805 | Artemisinin and a Series of Novel Endoperoxide Antimalarials Exert Early Effects on Digestive Vacuole Morphology |
| Q27671783 | Bestatin-based chemical biology strategy reveals distinct roles for malaria M1- and M17-family aminopeptidases |
| Q33690305 | Biochemical characterization of Plasmodium falciparum dipeptidyl aminopeptidase 1 |
| Q33638392 | Bisquinoline antimalarials: their role in malaria chemotherapy |
| Q28536452 | Blocking Plasmodium falciparum development via dual inhibition of hemoglobin degradation and the ubiquitin proteasome system by MG132 |
| Q37635978 | Cathepsin proteases in Toxoplasma gondii |
| Q39559476 | Central role of hemoglobin degradation in mechanisms of action of 4-aminoquinolines, quinoline methanols, and phenanthrene methanols |
| Q36744868 | Changes in the plasmodial surface anion channel reduce leupeptin uptake and can confer drug resistance in Plasmodium falciparum-infected erythrocytes. |
| Q44510202 | Characterization and classification of five cysteine proteinases expressed by Paragonimus westermani adult worm |
| Q58646654 | Characterization of a cysteine proteinase from Taenia crassiceps cysts |
| Q41745894 | Characterization of native and recombinant falcipain-2, a principal trophozoite cysteine protease and essential hemoglobinase of Plasmodium falciparum |
| Q73059919 | Characterization of native falcipain, an enzyme involved in Plasmodium falciparum hemoglobin degradation |
| Q27973707 | Characterization of the autophagy marker protein Atg8 reveals atypical features of autophagy in Plasmodium falciparum |
| Q34811649 | Chloroquine resistance in the malarial parasite, Plasmodium falciparum |
| Q35814976 | Clonal viability measurements on Plasmodium falciparum to assess in vitro schizonticidal activity of leupeptin, chloroquine, and 5-fluoroorotate |
| Q33981743 | Comparison of efficacies of cysteine protease inhibitors against five strains of Plasmodium falciparum |
| Q47894327 | Computer modeling of small heat-shock metalloprotease of the human malaria parasite Plasmodium vivax |
| Q31102747 | Critical role of amino acid 23 in mediating activity and specificity of vinckepain-2, a papain-family cysteine protease of rodent malaria parasites |
| Q34065634 | Cystatin C--properties and use as diagnostic marker. |
| Q36788489 | Cysteamine, the natural metabolite of pantetheinase, shows specific activity against Plasmodium |
| Q46616785 | Cysteine protease falcipain 1 in Plasmodium falciparum is biochemically distinct from its isozymes |
| Q33649956 | Cysteine protease inhibitors as chemotherapy for parasitic infections |
| Q33886180 | Cysteine proteinases and the pathogenesis of amebiasis |
| Q37092278 | Cysteine proteinases of microorganisms and viruses. |
| Q36254819 | Differential stimulation of the Na+/H+ exchanger determines chloroquine uptake in Plasmodium falciparum |
| Q41936743 | Dual labeling with a far red probe permits analysis of growth and oxidative stress in P. falciparum-infected erythrocytes |
| Q45062318 | Evaluation of cysteine proteases of Plasmodium vivax as antimalarial drug targets: sequence analysis and sensitivity to cysteine protease inhibitors |
| Q27973740 | Expression and characterization of the Plasmodium falciparum haemoglobinase falcipain-3 |
| Q28484312 | Expression, characterization, and cellular localization of knowpains, papain-like cysteine proteases of the Plasmodium knowlesi malaria parasite |
| Q42951472 | Falcipain Inhibitors: Optimization Studies of the 2-Pyrimidinecarbonitrile Lead Series |
| Q41826054 | Falcipain-1, a Plasmodium falciparum cysteine protease with vaccine potential |
| Q36616566 | Ferrous iron-dependent delivery of therapeutic agents to the malaria parasite |
| Q43876950 | Folding of the Plasmodium falciparum cysteine protease falcipain-2 is mediated by a chaperone-like peptide and not the prodomain |
| Q30042887 | Four plasmepsins are active in the Plasmodium falciparum food vacuole, including a protease with an active-site histidine |
| Q35415207 | Functional expression of falcipain, a Plasmodium falciparum cysteine proteinase, supports its role as a malarial hemoglobinase. |
| Q37357541 | Gene disruption confirms a critical role for the cysteine protease falcipain-2 in hemoglobin hydrolysis by Plasmodium falciparum |
| Q48037131 | Generation of hemoglobin peptides in the acidic digestive vacuole of Plasmodium falciparum implicates peptide transport in amino acid production |
| Q34415972 | Hemoglobin catabolism and iron utilization by malaria parasites |
| Q33428555 | Hemoglobin cleavage site-specificity of the Plasmodium falciparum cysteine proteases falcipain-2 and falcipain-3. |
| Q30045945 | Hemoglobin degradation in the human malaria pathogen Plasmodium falciparum: a catabolic pathway initiated by a specific aspartic protease |
| Q28972254 | Hemoglobin degradation in the malaria parasite Plasmodium falciparum: an ordered process in a unique organelle |
| Q24304203 | Human α/β hydrolase domain containing 10 (ABHD10) is responsible enzyme for deglucuronidation of mycophenolic acid acyl-glucuronide in liver |
| Q42156927 | Identification and biochemical characterization of vivapains, cysteine proteases of the malaria parasite Plasmodium vivax |
| Q41728795 | Identification and characterization of a cathepsin-L-like peptidase in Eimeria tenella |
| Q30042132 | Identification and characterization of falcilysin, a metallopeptidase involved in hemoglobin catabolism within the malaria parasite Plasmodium falciparum |
| Q35106020 | Identification and deconvolution of cross-resistance signals from antimalarial compounds using multidrug-resistant Plasmodium falciparum strains |
| Q48039746 | Identification of a Plasmodium vivax heat-shock protein which contains a metalloprotease sequence motif |
| Q48036921 | Identification of hemoglobin degradation products in Plasmodium falciparum |
| Q44660942 | Independent intramolecular mediators of folding, activity, and inhibition for the Plasmodium falciparum cysteine protease falcipain-2. |
| Q41935455 | Inhibition by anti-malarial drugs of haemoglobin denaturation and iron release in acidified red blood cell lysates--a possible mechanism of their anti-malarial effect? |
| Q28540204 | Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites |
| Q35647780 | Inhibition of Plasmodium falciparum oocyst production by membrane-permeant cysteine protease inhibitor E64d |
| Q33893538 | Inhibition of a Plasmodium vinckei cysteine proteinase cures murine malaria |
| Q68925338 | Inhibition of intraerythrocytic development of Plasmodium falciparum by proteinase inhibitors |
| Q36181679 | Intracellular structures of normal and aberrant Plasmodium falciparum malaria parasites imaged by soft x-ray microscopy |
| Q43868723 | Intraerythrocytic Plasmodium falciparum utilizes only a fraction of the amino acids derived from the digestion of host cell cytosol for the biosynthesis of its proteins |
| Q30494843 | Irreversible effect of cysteine protease inhibitors on the release of malaria parasites from infected erythrocytes |
| Q31048202 | Isolation and characterization of a cDNA encoding a mammalian cathepsin L-like cysteine proteinase from Acanthamoeba healyi. |
| Q44377251 | Killing of intraerythrocytic Plasmodium falciparum by lysosomotropic amino acid esters |
| Q57252776 | Malarial proteinase? |
| Q44588019 | Metalloporphyrin probes for antimalarial drug action |
| Q41921871 | Metalloporphyrins inhibit beta-hematin (hemozoin) formation |
| Q39514455 | Metalloprotease activity in a small heat shock protein of the human malaria parasite Plasmodium vivax |
| Q28478016 | Mining a cathepsin inhibitor library for new antiparasitic drug leads |
| Q36868301 | Molecular and biochemical characterization of hemoglobinase, a cysteine proteinase, in Paragonimus westermani |
| Q34350086 | Molecular characterization and inhibition of a Plasmodium falciparum aspartic hemoglobinase. |
| Q36106723 | Mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, enlarge the parasite's food vacuole and alter drug sensitivities |
| Q38527649 | Naturally-occurring and recombinant forms of the aspartic proteinases plasmepsins I and II from the human malaria parasite Plasmodium falciparum |
| Q36579600 | Non-canonical maturation of two papain-family proteases in Toxoplasma gondii |
| Q34139669 | Order and specificity of the Plasmodium falciparum hemoglobin degradation pathway |
| Q35806583 | Plant Hormone Salicylic Acid Produced by a Malaria Parasite Controls Host Immunity and Cerebral Malaria Outcome |
| Q33193846 | Plasmepsin 4, the food vacuole aspartic proteinase found in all Plasmodium spp. infecting man. |
| Q52585854 | Plasmodium falciparum Falcipain-2a Polymorphisms in Southeast Asia and Their Association with Artemisinin Resistance. |
| Q34514862 | Plasmodium falciparum cysteine protease falcipain-1 is not essential in erythrocytic stage malaria parasites |
| Q39647939 | Plasmodium food vacuole plasmepsins are activated by falcipains |
| Q24538763 | Potencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malaria |
| Q30661998 | Potent second generation vinyl sulfonamide inhibitors of the trypanosomal cysteine protease cruzain |
| Q37064248 | Proteases of malaria parasites: new targets for chemotherapy |
| Q44432998 | Protective immune responses against protease-like antigens of the murine malaria parasite Plasmodium vinckei |
| Q31157525 | Proteolysis at a specific extracellular residue implicates integral membrane CLAG3 in malaria parasite nutrient channels |
| Q73613112 | Proteolysis of Plasmodium falciparum surface antigen, Pfs230, during gametogenesis |
| Q36755885 | Quinoline-containing antimalarials—mode of action, drug resistance and its reversal an update with unresolved puzzles |
| Q37063869 | Recognition of Red Cells by Malaria Parasites: The Role of Erythrocyte-Binding Proteins |
| Q43681696 | Recombinant falcipain-2 cleaves erythrocyte membrane ankyrin and protein 4.1. |
| Q44036735 | Reducing requirements for hemoglobin hydrolysis by Plasmodium falciparum cysteine proteases |
| Q31081478 | Resistance of Entamoeba histolytica to the cysteine proteinase inhibitor E64 is associated with secretion of pro-enzymes and reduced pathogenicity |
| Q39947285 | Role of Plasmodium falciparum digestive vacuole plasmepsins in the specificity and antimalarial mode of action of cysteine and aspartic protease inhibitors |
| Q92459661 | Role of Toxoplasma gondii Chloroquine Resistance Transporter in Bradyzoite Viability and Digestive Vacuole Maintenance |
| Q41913918 | Selection of cysteine protease inhibitor-resistant malaria parasites is accompanied by amplification of falcipain genes and alteration in inhibitor transport |
| Q38344740 | Soluble expression of a functionally active Plasmodium falciparum falcipain-2 fused to maltose-binding protein in Escherichia coli |
| Q44056198 | Stage-specific antimalarial activity of cysteine protease inhibitors |
| Q48031305 | Structural and functional characterization of Falcipain-2, a hemoglobinase from the malarial parasite Plasmodium falciparum |
| Q44858731 | Structural characterization of vivapain-2 and vivapain-3, cysteine proteases from Plasmodium vivax: comparative protein modeling and docking studies |
| Q42846000 | Structural determinants of specificity in the cysteine protease cruzain |
| Q34722632 | Structure-activity relationships for inhibition of cysteine protease activity and development of Plasmodium falciparum by peptidyl vinyl sulfones |
| Q47842705 | Structure-based design, synthesis and evaluation of conformationally constrained cysteine protease inhibitors |
| Q36252297 | Structure-based inhibitor design by using protein models for the development of antiparasitic agents |
| Q27653357 | Structures of Falcipain-2 and Falcipain-3 Bound to Small Molecule Inhibitors: Implications for Substrate Specificity ‡ |
| Q47973961 | Study of protein complexes via homology modeling, applied to cysteine proteases and their protein inhibitors |
| Q44935373 | Synthesis and antiplasmodial activity of a cysteine protease-inhibiting biotinylated aziridine-2,3-dicarboxylate |
| Q42719359 | Synthesis and evaluation of peptidyl α,β-unsaturated carbonyl derivatives as anti-malarial calpain inhibitors |
| Q46273729 | Synthesis of novel benzimidazole acrylonitriles for inhibition of Plasmodium falciparum growth by dual target inhibition |
| Q61066428 | The Importance of the Active Site Histidine for the Activity of Epoxide- or Aziridine-Based Inhibitors of Cysteine Proteases |
| Q36696202 | The antimalarial natural product symplostatin 4 is a nanomolar inhibitor of the food vacuole falcipains |
| Q34999498 | The integration of genomic and structural information in the development of high affinity plasmepsin inhibitors |
| Q67879086 | The native form of the Plasmodium falciparum Pf68 neutral proteinase is a 105,000-Da polypeptide |
| Q37392803 | The proteasome inhibitor epoxomicin has potent Plasmodium falciparum gametocytocidal activity |
| Q43733737 | The role of aminopeptidases in haemoglobin degradation in Plasmodium falciparum-infected erythrocytes |
| Q34159296 | Theories on malarial pigment formation and quinoline action |
| Q38109627 | Trafficked Proteins-Druggable in Plasmodium falciparum? |
| Q37181425 | Understanding the structural basis of substrate recognition by Plasmodium falciparum plasmepsin V to aid in the design of potent inhibitors. |
| Q47891342 | Use of variability in the stage-specific transcription levels of Plasmodium falciparum in the selection of target genes |
| Q27646557 | Vinyl Sulfones as Antiparasitic Agents and a Structural Basis for Drug Design |
| Q30921085 | cDNA cloning of a novel cysteine protease of Plasmodium falciparum |
Search more.