Pol I transcription and pre-rRNA processing are coordinated in a transcription-dependent manner in mammalian cells

scientific article published on 15 November 2006

Pol I transcription and pre-rRNA processing are coordinated in a transcription-dependent manner in mammalian cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1091/MBC.E06-03-0249
P932PMC publication ID1783775
P698PubMed publication ID17108330

P2093author name stringD Chen
S Huang
D J Leary
R Gilmore
C Wang
D A Dean
J Z Gasiorowski
E K L Chan
J T Norton
K Kopp
P2860cites workA common core RNP structure shared between the small nucleoar box C/D RNPs and the spliceosomal U4 snRNPQ24290525
The sigma(70)-like motif: a eukaryotic RNA binding domain unique to a superfamily of proteins required for ribosome biogenesisQ24292366
The human Imp3 and Imp4 proteins form a ternary complex with hMpp10, which only interacts with the U3 snoRNA in 60-80S ribonucleoprotein complexesQ24298425
90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factorsQ24302526
Nucleolar KKE/D repeat proteins Nop56p and Nop58p interact with Nop1p and are required for ribosome biogenesisQ24308842
Rcl1p, the yeast protein similar to the RNA 3'-phosphate cyclase, associates with U3 snoRNP and is required for 18S rRNA biogenesisQ24599738
Human autoantibody to RNA polymerase I transcription factor hUBF. Molecular identity of nucleolus organizer region autoantigen NOR-90 and ribosomal RNA transcription upstream binding factorQ24675671
Structure determination of fibrillarin from the hyperthermophilic archaeon Pyrococcus furiosusQ27643160
Imp3p and Imp4p, two specific components of the U3 small nucleolar ribonucleoprotein that are essential for pre-18S rRNA processingQ27930834
Synthesis and assembly of the box C+D small nucleolar RNPsQ27933850
Nop58p is a common component of the box C+D snoRNPs that is required for snoRNA stabilityQ27937123
A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesisQ27937306
A U3 snoRNP protein with homology to splicing factor PRP4 and G beta domains is required for ribosomal RNA processingQ27937558
RNA polymerase I transcription and pre-rRNA processing are linked by specific SSU processome componentsQ27938887
The economics of ribosome biosynthesis in yeastQ28131645
Functional Cooperativity Between Transcription Factors UBF1 and SL1 Mediates Human Ribosomal RNA SynthesisQ28297909
Preferential cleavage in pre-ribosomal RNA byprotein B23 endoribonucleaseQ28568636
Ribosome assembly in eukaryotesQ29615231
Pre-ribosomes on the road from the nucleolus to the cytoplasmQ29616319
Pre-18S ribosomal RNA is structurally compacted into the SSU processome prior to being cleaved from nascent transcripts in Saccharomyces cerevisiaeQ30435434
Visualization of Nucleolar GenesQ34054255
Site-specific cross-linking analyses reveal an asymmetric protein distribution for a box C/D snoRNP.Q34089829
Life on a planet of its own: regulation of RNA polymerase I transcription in the nucleolusQ34214625
Rules of engagement: co-transcriptional recruitment of pre-mRNA processing factorsQ34419716
TBP-TAF complex SL1 directs RNA polymerase I pre-initiation complex formation and stabilizes upstream binding factor at the rDNA promoter.Q34428135
Small nucleolar RNAs: versatile trans-acting molecules of ancient evolutionary origin.Q34546169
Building an efficient factory: where is pre-rRNA synthesized in the nucleolus?Q34659620
Isolation of U3 snoRNP from CHO cells: a novel 55 kDa protein binds to the central part of U3 snoRNAQ35018776
Epigenetic silencing of RNA polymerase I transcriptionQ35201463
The nucleolus and transcription of ribosomal genesQ35935633
Synthesis of functional eukaryotic ribosomal RNAs in trans: development of a novel in vivo rDNA system for dissecting ribosome biogenesisQ36071800
Crosstalk in gene expression: coupling and co-regulation of rDNA transcription, pre-ribosome assembly and pre-rRNA processingQ36131510
A structural perspective of CTD functionQ36167411
Association of yeast RNA polymerase I with a nucleolar substructure active in rRNA synthesis and processingQ36327643
The dynamics of postmitotic reassembly of the nucleolusQ36328472
Nucleolar components involved in ribosome biogenesis cycle between the nucleolus and nucleoplasm in interphase cellsQ36342404
A plant snoRNP complex containing snoRNAs, fibrillarin, and nucleolin-like proteins is competent for both rRNA gene binding and pre-rRNA processing in vitroQ36700946
Upstream binding factor association induces large-scale chromatin decondensationQ37589616
Identification of thein vivoandin vitroorigin of transcription in human rDNAQ40464982
UBF-binding site arrays form pseudo-NORs and sequester the RNA polymerase I transcription machinery.Q40480663
Tumor suppressor ARF degrades B23, a nucleolar protein involved in ribosome biogenesis and cell proliferation.Q40613625
Nuclear RanGTP is not required for targeting small nucleolar RNAs to the nucleolusQ40686854
Import of plasmid DNA into the nucleus is sequence specificQ41131215
Postmitotic nuclear retention of episomal plasmids is altered by DNA labeling and detection methodsQ41762666
Clones of human ribosomal DNA containing the complete 18 S-rRNA and 28 S-rRNA genes. Characterization, a detailed map of the human ribosomal transcription unit and diversity among clones.Q41811274
Mutational analysis of fibrillarin and its mobility in living human cellsQ42934783
Herpes simplex virus type 1-induced modifications in the distribution of nucleolar B-36 proteinQ45847549
The CTD code.Q53963724
Ribosomal RNA transcription in vitro is species specificQ59094618
Rapid initial cleavage of nascent pre-rRNA transcripts in yeastQ68130748
Immunocytochemical characterization of human NOR-90 (upstream binding factor) and associated antigens reactive with autoimmune sera. Two MR forms of NOR-90/hUBF autoantigensQ72155117
Isolation of S. cerevisiae snRNPs: comparison of U1 and U4/U6.U5 to their human counterpartsQ72336928
Two ribosomal DNA-binding factors interact with a cluster of motifs on the 5' external transcribed spacer, upstream from the primary pre-rRNA processing site in a higher plantQ73678158
What better measure than ribosome synthesis?Q80872567
P433issue2
P304page(s)394-403
P577publication date2006-11-15
P1433published inMolecular Biology of the CellQ2338259
P1476titlePol I transcription and pre-rRNA processing are coordinated in a transcription-dependent manner in mammalian cells
P478volume18

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cites work (P2860)
Q337693091A6/DRIM, a novel t-UTP, activates RNA polymerase I transcription and promotes cell proliferation
Q36228583Analysis of rRNA processing and translation in mammalian cells using a synthetic 18S rRNA expression system
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Q34041740Conditional inactivation of Upstream Binding Factor reveals its epigenetic functions and the existence of a somatic nucleolar precursor body
Q92167389Differential expression of duplicated ribosomal protein genes modifies ribosome composition in response to stress
Q28474442Function and assembly of a chromatin-associated RNase P that is required for efficient transcription by RNA polymerase I
Q88527539HMGB proteins involved in TOR signaling as general regulators of cell growth by controlling ribosome biogenesis
Q37295592Impaired rRNA synthesis triggers homeostatic responses in hippocampal neurons
Q34115905Intranuclear trafficking of episomal DNA is transcription-dependent
Q28255964LAS1L interacts with the mammalian Rix1 complex to regulate ribosome biogenesis
Q39677695Las1L is a nucleolar protein required for cell proliferation and ribosome biogenesis
Q28507301Mutations in TFIIH causing trichothiodystrophy are responsible for defects in ribosomal RNA production and processing
Q36620686Old drug, new target: ellipticines selectively inhibit RNA polymerase I transcription
Q28910336Recruitment of factors linking transcription and processing of pre-rRNA to NOR chromatin is UBF-dependent and occurs independent of transcription in human cells
Q26785508Targeted cancer therapy with ribosome biogenesis inhibitors: a real possibility?
Q38124258The emerging role of RNA polymerase I transcription machinery in human malignancy: a clinical perspective.
Q33772981The nucleolar size is associated to the methylation status of ribosomal DNA in breast carcinomas
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Q39025278UBF complexes with phosphatidylinositol 4,5-bisphosphate in nucleolar organizer regions regardless of ongoing RNA polymerase I activity
Q34025090hALP, a novel transcriptional U three protein (t-UTP), activates RNA polymerase I transcription by binding and acetylating the upstream binding factor (UBF)