Silence of MACC1 expression by RNA interference inhibits proliferation, invasion and metastasis, and promotes apoptosis in U251 human malignant glioma cells

scientific article published on 3 June 2015

Silence of MACC1 expression by RNA interference inhibits proliferation, invasion and metastasis, and promotes apoptosis in U251 human malignant glioma cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3892/MMR.2015.3886
P932PMC publication ID4526050
P698PubMed publication ID26043756
P5875ResearchGate publication ID277779612

P2093author name stringGang Li
Hongwen Zhao
Wei Tan
Xiaofei Li
Bing Dai
Aiping Wang
Longfeng Sun
P2860cites workThe Bcl-2 apoptotic switch in cancer development and therapyQ24620437
Different roles for cyclins D1 and E in regulation of the G1-to-S transitionQ24651978
The role of Bcl-2 family proteins in therapy responses of malignant astrocytic gliomas: Bcl2L12 and beyondQ26851645
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastomaQ27860910
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Cyclin B1/Cdk1 coordinates mitochondrial respiration for cell-cycle G2/M progressionQ28910225
Unexpected domain composition of MACC1 links MET signaling and apoptosis.Q30157235
MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasisQ30157439
Regulation of glioblastoma progression by cord blood stem cells is mediated by downregulation of cyclin D1.Q33859439
MACC1 down-regulation inhibits proliferation and tumourigenicity of nasopharyngeal carcinoma cells through Akt/β-catenin signaling pathwayQ34662122
Mechanisms of tumour invasion and metastasis: emerging targets for therapyQ34837655
Effects of metastasis-associated in colon cancer 1 inhibition by small hairpin RNA on ovarian carcinoma OVCAR-3 cellsQ35237704
Ways of dying: multiple pathways to apoptosis.Q35560936
Molecular mechanisms of glioma cell migration and invasionQ36021576
MACC1: A potential molecule associated with pancreatic cancer metastasis and chemoresistanceQ36424134
Drug insight: cancer therapy strategies based on restoration of endogenous cell death mechanismsQ36529789
Impact of MACC1 on human malignant glioma progression and patients' unfavorable prognosisQ37312752
Colon cancer metastasis: MACC1 and Met as metastatic pacemakersQ37576722
Regulation of Bax mitochondrial localization by Bcl-2 and Bcl-x(L): keep your friends close but your enemies closerQ38051964
Glioblastoma and other malignant gliomas: a clinical review.Q38160159
Maturation promoting factor, cyclin and the control of M-phaseQ38376052
MACC1 induces metastasis in ovarian carcinoma by upregulating hepatocyte growth factor receptor c-METQ38976760
Mediation of multiple pathways regulating cell proliferation, migration, and apoptosis in the human malignant glioma cell line U87MG via unphosphorylated STAT1: laboratory investigationQ39163732
Knockdown of MACC1 expression suppressed hepatocellular carcinoma cell migration and invasion and inhibited expression of MMP2 and MMP9.Q39227712
Antisense oligonucleotide against clusterin regulates human hepatocellular carcinoma invasion through transcriptional regulation of matrix metalloproteinase-2 and E-cadherinQ39285212
Deregulated cyclin E induces chromosome instabilityQ41692394
Overexpression of MACC1 leads to downstream activation of HGF/MET and potentiates metastasis and recurrence of colorectal cancerQ42276990
Effects of MACC1 siRNA on biological behaviors of HeLaQ43684978
Epidemiology of glial and non-glial brain tumours in EuropeQ44279365
MACC1 controls Met: what a difference an Sp1 site makesQ45216484
Overexpression of MACC1 protein and its clinical implications in patients with glioma.Q45991279
MACC 1 as a marker for peritoneal-disseminated gastric carcinomaQ46422794
Overexpression of MACC1 mRNA in lung adenocarcinoma is associated with postoperative recurrenceQ51742634
MACC 1 as a marker for vascular invasive hepatocellular carcinoma.Q54377590
MACC1 as a marker for advanced colorectal carcinoma.Q54416970
Regulatory phosphorylation of Bim: sorting out the ERK from the JNKQ81833475
Molecular diagnosis of MACC1 status in lung adenocarcinoma by immunohistochemical analysisQ83916068
P433issue3
P921main subjectRNA interferenceQ201993
P304page(s)3423-3431
P577publication date2015-06-03
P1433published inMolecular Medicine ReportsQ26842180
P1476titleSilence of MACC1 expression by RNA interference inhibits proliferation, invasion and metastasis, and promotes apoptosis in U251 human malignant glioma cells
P478volume12

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cites work (P2860)
Q92756391Circulating MACC1 Transcripts in Glioblastoma Patients Predict Prognosis and Treatment Response
Q37400156Kukoamine A inhibits human glioblastoma cell growth and migration through apoptosis induction and epithelial-mesenchymal transition attenuation
Q36621729Prognostic Impact of Modulators of G proteins in Circulating Tumor Cells from Patients with Metastatic Colorectal Cancer
Q28066094The potential therapeutic applications and prognostic significance of metastasis-associated in colon cancer-1 (MACC1) in cancers
Q49996685microRNA-598 inhibits cell proliferation and invasion of glioblastoma by directly targeting metastasis associated in colon cancer-1.

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