Identification of epigenetic modifications that contribute to pathogenesis in therapy-related AML: Effective integration of genome-wide histone modification with transcriptional profiles.

scientific article published on 29 May 2015

Identification of epigenetic modifications that contribute to pathogenesis in therapy-related AML: Effective integration of genome-wide histone modification with transcriptional profiles. is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1038820087
P356DOI10.1186/1755-8794-8-S2-S6
P932PMC publication ID4460748
P698PubMed publication ID26043758
P5875ResearchGate publication ID277779696

P50authorXinan YangQ83366108
P2093author name stringJohn M Cunningham
Bin Wang
P2860cites workIdentification of differentially expressed genes according to chemosensitivity in advanced ovarian serous adenocarcinomas: expression of GRIA2 predicts better survival.Q36075250
Text-mining assisted regulatory annotationQ36642396
Therapy-related myeloid leukemia.Q37009760
Dysregulated gene expression networks in human acute myelogenous leukemia stem cellsQ37097180
Epigenetic plasticity of chromatin in embryonic and hematopoietic stem/progenitor cells: therapeutic potential of cell reprogramming.Q37189326
Finding distal regulatory elements in the human genomeQ37621072
Identifying and mitigating bias in next-generation sequencing methods for chromatin biologyQ38249872
Transcriptional profiles of unirradiated or UV-irradiated human cells expressing either the cancer-prone XPB/CS allele or the noncancer-prone XPB/TTD allele.Q38332883
Semaphorin 3A upregulates FOXO 3a-dependent MelCAM expression leading to attenuation of breast tumor growth and angiogenesis.Q39004667
High mobility group box 1 promotes tumor cell migration through epigenetic silencing of semaphorin 3A.Q39064881
Enhancer of zeste homolog 2 is overexpressed and contributes to epigenetic inactivation of p21 and phosphatase and tensin homolog in B-cell acute lymphoblastic leukemiaQ39283792
The transcriptional repressor NIPP1 is an essential player in EZH2-mediated gene silencing.Q40088699
Cancer cell lines as genetic models of their parent histology: analyses based on array comparative genomic hybridizationQ40144602
Gene expression profiles associated with response to chemotherapy in epithelial ovarian cancersQ40391221
Multiple mechanisms deregulate EZH2 and histone H3 lysine 27 epigenetic changes in myeloid malignancies.Q46045890
A description of the Molecular Signatures Database (MSigDB) Web siteQ46317320
Regression of abdominal aortic aneurysm by inhibition of c-Jun N-terminal kinaseQ46823363
Ectopic expression of the histone methyltransferase Ezh2 in haematopoietic stem cells causes myeloproliferative diseaseQ50594569
The functional and mechanistic relatedness of EZH2 and menin in hepatocellular carcinomaQ51515581
Stem cell gene expression programs influence clinical outcome in human leukemia.Q51856192
OrderedList--a bioconductor package for detecting similarity in ordered gene listsQ51937584
Statistical Methods for Identifying Differentially Expressed Genes in DNA MicroarraysQ58618312
Overexpression of the EZH2, RING1 and BMI1 genes is common in myelodysplastic syndromes: relation to adverse epigenetic alteration and poor prognostic scoringQ82704793
Defining functional DNA elements in the human genomeQ22066251
Genomic views of distant-acting enhancersQ22122210
Genome-wide maps of chromatin state in pluripotent and lineage-committed cellsQ24632506
The epithelial-mesenchymal transition generates cells with properties of stem cellsQ24650786
Loss of expression of the Hoxa-9 homeobox gene impairs the proliferation and repopulating ability of hematopoietic stem cellsQ24670084
EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cellsQ24672969
Statistical significance for genomewide studiesQ24681264
Role of histone H3 lysine 27 methylation in Polycomb-group silencingQ28131795
Cis-regulatory elements: molecular mechanisms and evolutionary processes underlying divergenceQ29032100
The ENCODE (ENCyclopedia Of DNA Elements) ProjectQ29547219
Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disordersQ29614510
The polycomb group protein EZH2 is involved in progression of prostate cancerQ29614514
Distribution and intensity of constraint in mammalian genomic sequenceQ29614574
Adjusting batch effects in microarray expression data using empirical Bayes methodsQ29614937
Tackling the widespread and critical impact of batch effects in high-throughput dataQ30004214
A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencingQ33268624
Meta-analysis of several gene lists for distinct types of cancer: a simple way to reveal common prognostic markersQ33268788
Global rank-invariant set normalization (GRSN) to reduce systematic distortions in microarray dataQ33389620
Molecular signature of cell cycle exit induced in human T lymphoblasts by IL-2 withdrawalQ33463820
Mechanism-anchored profiling derived from epigenetic networks predicts outcome in acute lymphoblastic leukemiaQ33504384
Identification of protein-coding and non-coding RNA expression profiles in CD34+ and in stromal cells in refractory anemia with ringed sideroblastsQ33633465
Genome wide screen identifies microsatellite markers associated with acute adverse effects following radiotherapy in cancer patientsQ33654687
Association of a leukemic stem cell gene expression signature with clinical outcomes in acute myeloid leukemia.Q33873844
Strategies for aggregating gene expression data: the collapseRows R functionQ33981973
Genome-wide quantitative enhancer activity maps identified by STARR-seqQ34035127
Topology of mammalian developmental enhancers and their regulatory landscapesQ34379841
Expression profiling of CD34+ hematopoietic stem/ progenitor cells reveals distinct subtypes of therapy-related acute myeloid leukemia.Q34380411
An approach for the identification of targets specific to bone metastasis using cancer genes interactome and gene ontology analysisQ34482311
Loss of heterozygosity in 7q myeloid disorders: clinical associations and genomic pathogenesisQ34637945
Overexpressed DNA Polymerase Iota Regulated by JNK/c-Jun Contributes to Hypermutagenesis in Bladder CancerQ34902441
Altered Hematopoietic Cell Gene Expression Precedes Development of Therapy-Related Myelodysplasia/Acute Myeloid Leukemia and Identifies Patients at RiskQ35563771
Semaphorin 3A overcomes cancer hypoxia and metastatic dissemination induced by antiangiogenic treatment in miceQ35913662
P4510describes a project that useslimmaQ112236343
P304page(s)S6
P577publication date2015-05-29
P1433published inBMC Medical GenomicsQ15754662
P1476titleIdentification of epigenetic modifications that contribute to pathogenesis in therapy-related AML: Effective integration of genome-wide histone modification with transcriptional profiles
P478volume8 Suppl 2

Reverse relations

cites work (P2860)
Q42557515Connecting the dots in translational bioinformatics: TBC 2014 collection
Q30952534Seq2pathway: an R/Bioconductor package for pathway analysis of next-generation sequencing data

Search more.