scholarly article | Q13442814 |
P2093 | author name string | Edward E Schmidt | |
Mario R Capecchi | |||
Elias S J Arnér | |||
Sofi Eriksson | |||
Justin R Prigge | |||
Sonya V Iverson | |||
Tesia A Meade | |||
P2860 | cites work | Essential role for mitochondrial thioredoxin reductase in hematopoiesis, heart development, and heart function | Q24563493 |
The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress | Q24648021 | ||
Cytoprotective Nrf2 pathway is induced in chronically txnrd 1-deficient hepatocytes | Q27346748 | ||
Thioredoxin deficiency in yeast prolongs S phase and shortens the G1 interval of the cell cycle | Q27934271 | ||
Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase | Q28508079 | ||
Cytoplasmic thioredoxin reductase is essential for embryogenesis but dispensable for cardiac development | Q28510029 | ||
Fundamental cellular processes do not require vertebrate-specific sequences within the TATA-binding protein | Q28511553 | ||
Characterization of alternative cytosolic forms and cellular targets of mouse mitochondrial thioredoxin reductase | Q28570489 | ||
Effects of thioredoxin reductase-1 deletion on embryogenesis and transcriptome | Q28588321 | ||
ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEOTIDES. IV. ISOLATION AND CHARACTERIZATION OF THIOREDOXIN, THE HYDROGEN DONOR FROM ESCHERICHIA COLI B | Q77147031 | ||
Preparation and assay of mammalian thioredoxin and thioredoxin reductase | Q77907868 | ||
Thioredoxin h5 is required for victorin sensitivity mediated by a CC-NBS-LRR gene in Arabidopsis | Q79830702 | ||
Redox atlas of the mouse. Immunohistochemical detection of glutaredoxin-, peroxiredoxin-, and thioredoxin-family proteins in various tissues of the laboratory mouse | Q84649121 | ||
Molecular mechanisms of thioredoxin and glutaredoxin as hydrogen donors for Mammalian s phase ribonucleotide reductase | Q28594627 | ||
Physiological functions of thioredoxin and thioredoxin reductase | Q29615600 | ||
Regulatory mechanisms controlling gene expression mediated by the antioxidant response element | Q29616504 | ||
Targeting thioredoxin reductase 1 reduction in cancer cells inhibits self-sufficient growth and DNA replication | Q33304452 | ||
Inactivation of thioredoxin reductases reveals a complex interplay between thioredoxin and glutathione pathways in Arabidopsis development | Q33344187 | ||
Cre activity in fetal albCre mouse hepatocytes: Utility for developmental studies | Q33688941 | ||
Hepatocytes lacking thioredoxin reductase 1 have normal replicative potential during development and regeneration | Q33951227 | ||
Antioxidant function of thioredoxin and glutaredoxin systems | Q34159139 | ||
The absence of mitochondrial thioredoxin 2 causes massive apoptosis, exencephaly, and early embryonic lethality in homozygous mice | Q34463545 | ||
Selenoprotein TRXR-1 and GSR-1 are essential for removal of old cuticle during molting in Caenorhabditis elegans | Q34509011 | ||
Redox properties and evolution of human glutaredoxins | Q34634076 | ||
Hydrogen donor system for Escherichia coli ribonucleoside-diphosphate reductase dependent upon glutathione | Q35008888 | ||
Contributions of new hepatocyte lineages to liver growth, maintenance, and regeneration in mice | Q35132094 | ||
Unique function of the Nrf2-Keap1 pathway in the inducible expression of antioxidant and detoxifying enzymes | Q35708009 | ||
Intracellular cysteine delivery system that protects against toxicity by promoting glutathione synthesis | Q36316242 | ||
Cell size regulation, a mechanism that controls cellular RNA accumulation: consequences on regulation of the ubiquitous transcription factors Oct1 and NF-Y and the liver-enriched transcription factor DBP. | Q36382408 | ||
The thioredoxin system in cancer | Q36648323 | ||
Role of Nrf2-dependent ARE-driven antioxidant pathway in neuroprotection | Q37098154 | ||
Glutathione-dependent hydrogen donor system for calf thymus ribonucleoside-diphosphate reductase | Q37329773 | ||
Focus on mammalian thioredoxin reductases--important selenoproteins with versatile functions | Q37443200 | ||
Origin and turnover of mitochondrial glutathione | Q37523709 | ||
The use of thiols by ribonucleotide reductase | Q37790158 | ||
Glutathione-dependent synthesis of deoxyribonucleotides. Characterization of the enzymatic mechanism of Escherichia coli glutaredoxin | Q39243555 | ||
Loss of thioredoxin reductase 1 renders tumors highly susceptible to pharmacologic glutathione deprivation | Q39636538 | ||
High levels of thioredoxin reductase 1 modulate drug-specific cytotoxic efficacy | Q39797346 | ||
Reduction of Ribonucleotides | Q39805408 | ||
p53R2-dependent ribonucleotide reduction provides deoxyribonucleotides in quiescent human fibroblasts in the absence of induced DNA damage. | Q40148183 | ||
Thioredoxin reductase 1 deficiency reverses tumor phenotype and tumorigenicity of lung carcinoma cells | Q40299705 | ||
The Function of Thioredoxin and Glutathione in Deoxyribonucleic Acid Synthesis | Q40809877 | ||
On the coupling between DNA replication and mitosis | Q44308303 | ||
Absolute gene expression patterns of thioredoxin and glutaredoxin redox systems in mouse | Q44572770 | ||
Analyses of glutathione reductase hypomorphic mice indicate a genetic knockout | Q45041246 | ||
Human Protein Atlas of redox systems - what can be learnt? | Q46627604 | ||
Nonheme iron as a cofactor in ribonucleotide reductase from E. coli | Q47814829 | ||
Early embryonic lethality caused by targeted disruption of the mouse thioredoxin gene. | Q52521278 | ||
Thioredoxin is required for deoxyribonucleotide pool maintenance during S phase. | Q53629818 | ||
Iron and free radical in ribonucleotide reductase. Exchange of iron and Mössbauer spectroscopy of the protein B2 subunit of the Escherichia coli enzyme. | Q53705195 | ||
Different cellular distribution of thioredoxin and subunit M1 of ribonucleotide reductase in rat tissues | Q68865011 | ||
Mechanism of B12-dependent ribonucleotide reductase | Q70252747 | ||
Ploidy and nuclearity of rat hepatocytes after compensatory regeneration or mitogen-induced liver growth | Q70488957 | ||
P433 | issue | 4 | |
P921 | main subject | glutathione | Q116907 |
P304 | page(s) | 803-810 | |
P577 | publication date | 2011-12-08 | |
P1433 | published in | Free Radical Biology and Medicine | Q5500023 |
P1476 | title | Hepatocyte DNA replication in growing liver requires either glutathione or a single allele of txnrd1. | |
P478 | volume | 52 |
Q42259921 | A Txnrd1-dependent metabolic switch alters hepatic lipogenesis, glycogen storage, and detoxification |
Q37577458 | APR-246/PRIMA-1MET inhibits thioredoxin reductase 1 and converts the enzyme to a dedicated NADPH oxidase |
Q35206449 | Dietary methionine can sustain cytosolic redox homeostasis in the mouse liver. |
Q52855141 | Dietary-Induced Chronic Hypothyroidism Negatively Affects Rat Follicular Development and Ovulation Rate and Is Associated with Oxidative Stress. |
Q38823023 | Dual targeting of the thioredoxin and glutathione systems in cancer and HIV. |
Q35652974 | Expression of Selenoproteins Is Maintained in Mice Carrying Mutations in SECp43, the tRNA Selenocysteine 1 Associated Protein (Trnau1ap). |
Q39278850 | Glutathione and glutaredoxin act as a backup of human thioredoxin reductase 1 to reduce thioredoxin 1 preventing cell death by aurothioglucose |
Q47118576 | Hepatocyte Hyperproliferation upon Liver-Specific Co-disruption of Thioredoxin-1, Thioredoxin Reductase-1, and Glutathione Reductase. |
Q42114301 | Human CD4+ T cells require exogenous cystine for glutathione and DNA synthesis |
Q26778366 | Interplay between cytosolic disulfide reductase systems and the Nrf2/Keap1 pathway |
Q52731954 | Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy. |
Q51730944 | NADPH-dependent and -independent Disulfide Reductase Systems. |
Q38914638 | Non-enzymatic action of RRM1 protein upregulates PTEN leading to inhibition of colorectal cancer metastasis. |
Q38645501 | Oxidative Stress Gene Expression Profile Correlates with Cancer Patient Poor Prognosis: Identification of Crucial Pathways Might Select Novel Therapeutic Approaches. |
Q28392715 | Paradoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health Implications |
Q30580089 | Sec-containing TrxR1 is essential for self-sufficiency of cells by control of glucose-derived H2O2. |
Q37106059 | Should autism be considered a canary bird telling that Homo sapiens may be on its way to extinction? |
Q47253881 | The A to Z of modulated cell patterning by mammalian thioredoxin reductases. |
Q28397704 | The effects of chromium(VI) on the thioredoxin system: implications for redox regulation |
Q39095779 | The metabolic function of hepatocytes differentiated from human mesenchymal stem cells is inversely related to cellular glutathione levels |
Q33632775 | The thioredoxin reductase-1 inhibitor aurothioglucose attenuates lung injury and improves survival in a murine model of acute respiratory distress syndrome |
Q34370090 | The thioredoxin system in neonatal lung disease |
Q91894840 | The thioredoxin-1 and glutathione/glutaredoxin-1 systems redundantly fuel murine B-cell development and responses |
Q55383421 | The thioredoxin-1 system is essential for fueling DNA synthesis during T-cell metabolic reprogramming and proliferation. |
Q41982836 | The yin and yang of nrf2-regulated selenoproteins in carcinogenesis |
Q39316517 | Thiophosphate and selenite conversely modulate cell death induced by glutathione depletion or cisplatin: effects related to activity and Sec contents of thioredoxin reductase. |
Q38777415 | Thioredoxin Reductase Inhibition Attenuates Neonatal Hyperoxic Lung Injury and Enhances Nuclear Factor E2-Related Factor 2 Activation. |
Q36447023 | Thioredoxin reductase 1 protects against chemically induced hepatocarcinogenesis via control of cellular redox homeostasis |
Q37147096 | Thioredoxin-1 mediates hypoxia-induced pulmonary artery smooth muscle cell proliferation |
Q28389739 | Thioredoxins, glutaredoxins, and peroxiredoxins--molecular mechanisms and health significance: from cofactors to antioxidants to redox signaling |
Q28080723 | TrxR1 as a potent regulator of the Nrf2-Keap1 response system |
Q40372633 | Type I IFNs Act upon Hematopoietic Progenitors To Protect and Maintain Hematopoiesis during Pneumocystis Lung Infection in Mice |
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