Expression of Selenoproteins Is Maintained in Mice Carrying Mutations in SECp43, the tRNA Selenocysteine 1 Associated Protein (Trnau1ap).

scientific article published on 4 June 2015

Expression of Selenoproteins Is Maintained in Mice Carrying Mutations in SECp43, the tRNA Selenocysteine 1 Associated Protein (Trnau1ap). is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2015PLoSO..1027349M
P356DOI10.1371/JOURNAL.PONE.0127349
P932PMC publication ID4456167
P698PubMed publication ID26043259
P5875ResearchGate publication ID279160710

P50authorUlrich SchweizerQ40281900
Lino TessarolloQ67472644
P2093author name stringBradley A Carlson
Dolph L Hatfield
Eileen Southon
Xue-Ming Xu
Doreen Braun
Noelia Fradejas
Paul Günter
Yassin Mahdi
P2860cites workBiosynthesis of selenocysteine on its tRNA in eukaryotesQ21145895
Functional characterization of the eukaryotic SECIS elements which direct selenocysteine insertion at UGA codonsQ24564454
RNA-dependent conversion of phosphoserine forms selenocysteine in eukaryotes and archaeaQ24678069
A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brainQ24811376
Cytoprotective Nrf2 pathway is induced in chronically txnrd 1-deficient hepatocytesQ27346748
Relaxation of Selective Constraints Causes Independent Selenoprotein Extinction in Insect GenomesQ27486602
Dual functions of codons in the genetic codeQ28281447
Efficient selenium transfer from mother to offspring in selenoprotein-P-deficient mice enables dose-dependent rescue of phenotypes associated with selenium deficiencyQ28512221
Identification of a protein component of a mammalian tRNA(Sec) complex implicated in the decoding of UGA as selenocysteineQ28569529
Eukaryotic initiation factor 4a3 is a selenium-regulated RNA-binding protein that selectively inhibits selenocysteine incorporationQ28575130
Secisbp2 is essential for embryonic development and enhances selenoprotein expressionQ28585049
Impaired selenoprotein expression in brain triggers striatal neuronal loss leading to co-ordination defects in miceQ28586937
Neuronal selenoprotein expression is required for interneuron development and prevents seizures and neurodegenerationQ28591775
Supramolecular complexes mediate selenocysteine incorporation in vivoQ28592179
Evidence for direct roles of two additional factors, SECp43 and soluble liver antigen, in the selenoprotein synthesis machineryQ28594216
Adjustments, extinction, and remains of selenocysteine incorporation machinery in the nematode lineage.Q33967919
Selective inhibition of selenocysteine tRNA maturation and selenoprotein synthesis in transgenic mice expressing isopentenyladenosine-deficient selenocysteine tRNA.Q33968398
Pyrrolysine encoded by UAG in Archaea: charging of a UAG-decoding specialized tRNA.Q34130079
Mutations Disrupting Selenocysteine Formation Cause Progressive Cerebello-Cerebral AtrophyQ34169430
Selenoprotein synthesis: an expansion of the genetic code.Q34766714
Selective removal of the selenocysteine tRNA [Ser]Sec gene (Trsp) in mouse mammary epitheliumQ34820264
Hepatocyte DNA replication in growing liver requires either glutathione or a single allele of txnrd1.Q35705409
The selenoproteome exhibits widely varying, tissue-specific dependence on selenoprotein P for selenium supplyQ35891602
Absence of selenoprotein P but not selenocysteine lyase results in severe neurological dysfunctionQ36074553
Early embryonic lethality caused by targeted disruption of the mouse selenocysteine tRNA gene (Trsp).Q36149734
Selenocysteine incorporation machinery and the role of selenoproteins in development and healthQ36557525
A functional link between housekeeping selenoproteins and phase II enzymesQ36712965
Autoantibodies against a serine tRNA-protein complex implicated in cotranslational selenocysteine insertionQ37251952
Novel structural determinants in human SECIS elements modulate the translational recoding of UGA as selenocysteineQ37385900
Hierarchical regulation of selenoprotein expression and sex-specific effects of seleniumQ37425614
Selenoproteins in Archaea and Gram-positive bacteriaQ37432484
Cerebellar hypoplasia in mice lacking selenoprotein biosynthesis in neuronsQ37699124
SBP2 binding affinity is a major determinant in differential selenoprotein mRNA translation and sensitivity to nonsense-mediated decayQ40082605
Reconstitution of selenocysteine incorporation reveals intrinsic regulation by SECIS elementsQ41268924
Hepatically derived selenoprotein P is a key factor for kidney but not for brain selenium supplyQ41870693
Gene disruption discloses role of selenoprotein P in selenium delivery to target tissuesQ42127289
Mammalian Trit1 is a tRNA([Ser]Sec)-isopentenyl transferase required for full selenoprotein expressionQ42827171
Mutation of megalin leads to urinary loss of selenoprotein P and selenium deficiency in serum, liver, kidneys and brainQ42960934
Hepatic deiodinase activity is dispensable for the maintenance of normal circulating thyroid hormone levels in miceQ46734482
Deletion of the selenocysteine tRNA gene in macrophages and liver results in compensatory gene induction of cytoprotective enzymes by Nrf2.Q46881389
Hepatic selenoprotein P (SePP) expression restores selenium transport and prevents infertility and motor-incoordination in Sepp-knockout miceQ46931534
Columns for rapid chromatographic separation of small amounts of tracer-labeled transfer ribonucleic acidsQ69956437
P275copyright licenseCreative Commons CC0 LicenseQ6938433
P6216copyright statuscopyrighted, dedicated to the public domain by copyright holderQ88088423
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectL-selenocysteineQ408663
P304page(s)e0127349
P577publication date2015-06-04
P1433published inPLOS OneQ564954
P1476titleExpression of Selenoproteins Is Maintained in Mice Carrying Mutations in SECp43, the tRNA Selenocysteine 1 Associated Protein (Trnau1ap).
P478volume10

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cites work (P2860)
Q89589129Bioinformatics of selenoproteins
Q56990436Mouse Models that Target Individual Selenoproteins
Q37391429Selenophosphate synthetase 1 is an essential protein with roles in regulation of redox homoeostasis in mammals
Q90327705Tolerance to Selenoprotein Loss Differs between Human and Mouse

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