| Q37266967 | A conditional transposon-based insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma. |
| Q36117429 | A kinase-deficient TrkC receptor isoform activates Arf6-Rac1 signaling through the scaffold protein tamalin. |
| Q39606057 | A new gain-of-function mouse line to study the role of Wnt3a in development and disease. |
| Q24655169 | A transposon-based genetic screen in mice identifies genes altered in colorectal cancer |
| Q30536540 | ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43. |
| Q57813809 | ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS |
| Q93181005 | ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS |
| Q28509375 | Ablation of TrkA function in the immune system causes B cell abnormalities |
| Q33332589 | An inducible and reversible mouse genetic rescue system |
| Q91584069 | Assaying Homodimers of NF-κB in Live Single Cells |
| Q36078249 | BDNF modulates heart contraction force and long-term homeostasis through truncated TrkB.T1 receptor activation |
| Q34743568 | BHLHB2 controls Bdnf promoter 4 activity and neuronal excitability. |
| Q28588378 | BRCA2 deficiency in mice leads to meiotic impairment and infertility |
| Q37336126 | BRCA2 minor transcript lacking exons 4-7 supports viability in mice and may account for survival of humans with a pathogenic biallelic mutation |
| Q28511014 | Bcl11a is essential for normal lymphoid development |
| Q43999190 | Brain-derived neurotrophic factor is essential for opiate-induced plasticity of noradrenergic neurons. |
| Q47833514 | CDK10 Mutations in Humans and Mice Cause Severe Growth Retardation, Spine Malformations, and Developmental Delays |
| Q28587532 | Cdc25b phosphatase is required for resumption of meiosis during oocyte maturation |
| Q39637413 | Cdk2 catalytic activity is essential for meiotic cell division in vivo |
| Q28210245 | Cdk2 knockout mice are viable |
| Q35103107 | Cerebellar ataxia, seizures, premature death, and cardiac abnormalities in mice with targeted disruption of the Cacna2d2 gene. |
| Q36929317 | Characterization of transgenic mice expressing cancer-associated variants of human NOTCH1 |
| Q36306041 | Chronic centrosome amplification without tumorigenesis |
| Q45166828 | Control of hyperphagia prevents obesity in BDNF heterozygous mice |
| Q36822669 | Coordinated transcriptional regulation of bone homeostasis by Ebf1 and Zfp521 in both mesenchymal and hematopoietic lineages |
| Q35844796 | Cyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration. |
| Q104569998 | Delayed onset of inherited ALS by deletion of the BDNF receptor TrkB.T1 is non-cell autonomous |
| Q34326654 | Deletion of the BDNF truncated receptor TrkB.T1 delays disease onset in a mouse model of amyotrophic lateral sclerosis |
| Q88180305 | Deletion of the endogenous TrkB.T1 receptor isoform restores the number of hippocampal CA1 parvalbumin-positive neurons and rescues long-term potentiation in pre-symptomatic mSOD1(G93A) ALS mice |
| Q33815183 | Detection of differential fetal and adult expression of chloride intracellular channel 4 (CLIC4) protein by analysis of a green fluorescent protein knock-in mouse line. |
| Q40184284 | Deubiquitinating enzyme VCIP135 dictates the duration of botulinum neurotoxin type A intoxication |
| Q92286005 | Differential Expression of the Transcription Factor GATA3 Specifies Lineage and Functions of Innate Lymphoid Cells |
| Q27314585 | Dystrophin is required for the normal function of the cardio-protective K(ATP) channel in cardiomyocytes |
| Q34850583 | Embryonic stem cell-derived motoneurons provide a highly sensitive cell culture model for botulinum neurotoxin studies, with implications for high-throughput drug discovery |
| Q47693355 | Emi2 Is Essential for Mouse Spermatogenesis. |
| Q37285341 | Endogenous truncated TrkB.T1 receptor regulates neuronal complexity and TrkB kinase receptor function in vivo |
| Q38708078 | Eradication of Tumors through Simultaneous Ablation of CD276/B7-H3-Positive Tumor Cells and Tumor Vasculature |
| Q24293168 | Essential regulation of lung surfactant homeostasis by the orphan G protein-coupled receptor GPR116 |
| Q28473926 | Essential role of chromatin remodeling protein Bptf in early mouse embryos and embryonic stem cells |
| Q34482189 | Exon 1 disruption alters tissue-specific expression of mouse p53 and results in selective development of B cell lymphomas |
| Q35652974 | Expression of Selenoproteins Is Maintained in Mice Carrying Mutations in SECp43, the tRNA Selenocysteine 1 Associated Protein (Trnau1ap). |
| Q36700876 | Expression of telomerase RNA template, but not telomerase reverse transcriptase, is limiting for telomere length maintenance in vivo |
| Q36753742 | Far Upstream Element Binding Protein Plays a Crucial Role in Embryonic Development, Hematopoiesis, and Stabilizing Myc Expression Levels. |
| Q38811850 | Fgf3-Fgf4-cis: A new mouse line for studying Fgf functions during mouse development. |
| Q35279496 | Folliculin-interacting proteins Fnip1 and Fnip2 play critical roles in kidney tumor suppression in cooperation with Flcn |
| Q36190966 | Functional evaluation of BRCA2 variants mapping to the PALB2-binding and C-terminal DNA-binding domains using a mouse ES cell-based assay. |
| Q28509184 | GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood-brain barrier |
| Q36880235 | Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs |
| Q44329217 | Gene targeting in mouse embryonic stem cells |
| Q28590926 | Generation and characterization of telomere length maintenance in tankyrase 2-deficient mice |
| Q100303984 | Generation of Functional Mouse Hippocampal Neurons |
| Q35895736 | Genetic deletion of trkB.T1 increases neuromuscular function |
| Q37157922 | Genetic substitution of Cdk1 by Cdk2 leads to embryonic lethality and loss of meiotic function of Cdk2 |
| Q28589826 | Genomic instability in mice lacking histone H2AX |
| Q28593369 | Hematopoietic, angiogenic and eye defects in Meis1 mutant animals |
| Q79074189 | Hepatic vascular tumors, angiectasis in multiple organs, and impaired spermatogenesis in mice with conditional inactivation of the VHL gene |
| Q36059447 | Histone H3 Lysine 27 demethylases Jmjd3 and Utx are required for T-cell differentiation |
| Q37291680 | Host-derived tumor endothelial marker 8 promotes the growth of melanoma |
| Q34105647 | IFN-gamma AU-rich element removal promotes chronic IFN-gamma expression and autoimmunity in mice |
| Q90783049 | Id1 Ablation Protects Hematopoietic Stem Cells from Stress-Induced Exhaustion and Aging |
| Q27319494 | Impaired Recall of Positional Memory following Chemogenetic Disruption of Place Field Stability. |
| Q53625915 | Insertion of c-Myc into Igh induces B-cell and plasma-cell neoplasms in mice. |
| Q27308072 | Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2 |
| Q28513499 | Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys |
| Q91268599 | Knockout of the non-essential gene SUGCT creates diet-linked, age-related microbiome disbalance with a diabetes-like metabolic syndrome phenotype |
| Q37499781 | LIM domain only-2 (LMO2) induces T-cell leukemia by two distinct pathways |
| Q36858688 | Lack of adrenomedullin in the mouse brain results in behavioral changes, anxiety, and lower survival under stress conditions. |
| Q33916747 | Loss of Cdk2 and cyclin A2 impairs cell proliferation and tumorigenesis |
| Q83437284 | Manipulating mouse embryonic stem cells |
| Q28507240 | Mastl is required for timely activation of APC/C in meiosis I and Cdk1 reactivation in meiosis II |
| Q36474580 | Meis1 preserves hematopoietic stem cells in mice by limiting oxidative stress |
| Q24536116 | Mitf and Tfe3, two members of the Mitf-Tfe family of bHLH-Zip transcription factors, have important but functionally redundant roles in osteoclast development |
| Q28512884 | Mitochondrial degeneration and not apoptosis is the primary cause of embryonic lethality in ceramide transfer protein mutant mice |
| Q36116636 | Mouse embryonic stem cells that express a NUP98-HOXD13 fusion protein are impaired in their ability to differentiate and can be complemented by BCR-ABL. |
| Q36625277 | Musashi1-CreER(T2) : a new cre line for conditional mutagenesis in neural stem cells |
| Q28595024 | Mutations in Cdh23 cause nonsyndromic hearing loss in waltzer mice |
| Q47958761 | Myc Regulates Chromatin Decompaction and Nuclear Architecture during B Cell Activation |
| Q28593248 | NT-3 replacement with brain-derived neurotrophic factor redirects vestibular nerve fibers to the cochlea |
| Q37239976 | Nedd4-2 haploinsufficiency causes hyperactivity and increased sensitivity to inflammatory stimuli |
| Q28591775 | Neuronal selenoprotein expression is required for interneuron development and prevents seizures and neurodegeneration |
| Q51274384 | Normal viability of Kai1/Cd82 deficient mice. |
| Q93195854 | Novel metabolic role for BDNF in pancreatic β-cell insulin secretion |
| Q64228212 | Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis |
| Q89091509 | POGZ Is Required for Silencing Mouse Embryonic β-like Hemoglobin and Human Fetal Hemoglobin Expression |
| Q28548051 | Phosphatase Inhibitors Function as Novel, Broad Spectrum Botulinum Neurotoxin Antagonists in Mouse and Human Embryonic Stem Cell-Derived Motor Neuron-Based Assays |
| Q103835799 | Prdm16 is a critical regulator of adult long-term hematopoietic stem cell quiescence |
| Q28589265 | RAD51C deficiency in mice results in early prophase I arrest in males and sister chromatid separation at metaphase II in females |
| Q37686241 | RanBPM (RanBP9) regulates mouse c-Kit receptor level and is essential for normal development of bone marrow progenitor cells. |
| Q35001695 | RanBPM is essential for mouse spermatogenesis and oogenesis |
| Q34282328 | RapGEF2 is essential for embryonic hematopoiesis but dispensable for adult hematopoiesis. |
| Q83230293 | Rbfox1 up-regulation impairs BDNF-dependent hippocampal LTP by dysregulating TrkB isoform expression levels |
| Q90633669 | Regulation of Kit Expression in Early Mouse Embryos and ES Cells |
| Q35684016 | SRC family kinase inhibitors antagonize the toxicity of multiple serotypes of botulinum neurotoxin in human embryonic stem cell-derived motor neurons |
| Q112760668 | SSSPTA is essential for serine palmitoyltransferase function during development and hematopoiesis |
| Q34820264 | Selective removal of the selenocysteine tRNA [Ser]Sec gene (Trsp) in mouse mammary epithelium |
| Q37391429 | Selenophosphate synthetase 1 is an essential protein with roles in regulation of redox homoeostasis in mammals |
| Q37304060 | Sexually dimorphic BDNF signaling directs sensory innervation of the mammary gland |
| Q115362079 | Spatial Shaping of Cochlear Innervation by Temporally Regulated Neurotrophin Expression |
| Q37599002 | Speedy A-Cdk2 binding mediates initial telomere-nuclear envelope attachment during meiotic prophase I independent of Cdk2 activation |
| Q36071817 | Spontaneous skin erosions and reduced skin and corneal wound healing characterize CLIC4(NULL) mice |
| Q91374042 | Sptlc1 is essential for myeloid differentiation and hematopoietic homeostasis |
| Q28205782 | Synaptic defects in ataxia mice result from a mutation in Usp14, encoding a ubiquitin-specific protease |
| Q37191597 | Tamalin is a critical mediator of electroconvulsive shock-induced adult neuroplasticity |
| Q33350164 | Tankyrase 1 and tankyrase 2 are essential but redundant for mouse embryonic development |
| Q35663645 | Telomere-associated protein TIN2 is essential for early embryonic development through a telomerase-independent pathway |
| Q91027439 | The Emergence and Functional Fitness of Memory CD4+ T Cells Require the Transcription Factor Thpok |
| Q28587887 | The folliculin-FNIP1 pathway deleted in human Birt-Hogg-Dubé syndrome is required for murine B-cell development |
| Q27307753 | The responsiveness of TrkB to BDNF and antidepressant drugs is differentially regulated during mouse development |
| Q35070890 | The scaffold protein Cybr is required for cytokine-modulated trafficking of leukocytes in vivo |
| Q36085339 | The zinc finger transcription factor Zbtb7b represses CD8-lineage gene expression in peripheral CD4+ T cells |
| Q35835921 | Transgenic mouse model expressing the caspase 6 fragment of mutant huntingtin |
| Q37633640 | TrkA in vivo function is negatively regulated by ubiquitination |
| Q114164701 | TrkA-cholinergic signaling modulates fear encoding and extinction learning in PTSD-like behavior |
| Q28275988 | c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells |