A new gain-of-function mouse line to study the role of Wnt3a in development and disease.

scientific article published on 13 July 2016

A new gain-of-function mouse line to study the role of Wnt3a in development and disease. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/DVG.22959
P932PMC publication ID6667172
P698PubMed publication ID27411055

P50authorLino TessarolloQ67472644
P2093author name stringRieko Ajima
Terry P Yamaguchi
Mark W Kennedy
Robert J Garriock
Ravindra B Chalamalasetty
P2860cites workAxin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-cateninQ24313571
Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin geneQ24529898
Wnt/β-catenin signaling and diseaseQ26823272
The Wnt signaling pathway in development and diseaseQ27861019
Wnt-3a regulates somite and tailbud formation in the mouse embryoQ28504870
Wnt3a-/--like phenotype and limb deficiency in Lef1(-/-)Tcf1(-/-) miceQ28509058
Inactivation of FGF8 in early mesoderm reveals an essential role in kidney developmentQ28585034
Wnt proteins are self-renewal factors for mammary stem cells and promote their long-term expansion in cultureQ28585146
Wnt3a links left-right determination with segmentation and anteroposterior axis elongationQ28589380
The segment polarity gene porcupine encodes a putative multitransmembrane protein involved in Wingless processingQ28616128
Regulation of the germinal center response by microRNA-155Q29547777
Wnt proteins are lipid-modified and can act as stem cell growth factorsQ29615009
Appropriate crypt formation in the uterus for embryo homing and implantation requires Wnt5a-ROR signalingQ33995495
Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cellsQ34149498
Expression of all Wnt genes and their secreted antagonists during mouse blastocyst and postimplantation developmentQ34416988
Mesogenin 1 is a master regulator of paraxial presomitic mesoderm differentiationQ34446339
T (Brachyury) is a direct target of Wnt3a during paraxial mesoderm specification.Q35210431
Lineage tracing of neuromesodermal progenitors reveals novel Wnt-dependent roles in trunk progenitor cell maintenance and differentiationQ35568242
Wnt-mediated self-renewal of neural stem/progenitor cells.Q36954317
Transcriptional profiling of Wnt3a mutants identifies Sp transcription factors as essential effectors of the Wnt/β-catenin pathway in neuromesodermal stem cellsQ37514374
Stem cell signaling. An integral program for tissue renewal and regeneration: Wnt signaling and stem cell controlQ38256327
Alternative Wnt Signaling Activates YAP/TAZ.Q38843582
Axin, a negative regulator of the wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of beta-cateninQ41036974
Wnt3a/beta-catenin signaling controls posterior body development by coordinating mesoderm formation and segmentation.Q51971087
Mouse Ripply2 is downstream of Wnt3a and is dynamically expressed during somitogenesis.Q51975063
Visualization of a short-range Wnt gradient in the intestinal stem-cell niche.Q52885366
A β-catenin gradient links the clock and wavefront systems in mouse embryo segmentationQ60492559
Multiple spatially specific enhancers are required to reconstruct the pattern of Hox-2.6 gene expressionQ68321893
Two-color in situ hybridization of whole-mount mouse embryosQ86914441
P433issue9
P304page(s)497-502
P577publication date2016-07-26
P1433published inGenesisQ5532784
P1476titleA new gain-of-function mouse line to study the role of Wnt3a in development and disease
P478volume54

Reverse relations

Q90201726A dorsal-ventral gradient of Wnt3a/β-catenin signals control hindgut extension and colon formationcites workP2860

Search more.