Impaired selenoprotein expression in brain triggers striatal neuronal loss leading to co-ordination defects in mice

scientific article

Impaired selenoprotein expression in brain triggers striatal neuronal loss leading to co-ordination defects in mice is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1042/BJ20140423
P932PMC publication ID4111790
P698PubMed publication ID24844465

P50authorBradley A CarlsonQ121401879
Dolph L HatfieldQ121401910
Eva K WirthQ40281864
Ulrich SchweizerQ40281900
P2093author name stringDonna M Driscoll
Angela C Miniard
Sandra Seeher
Yassin Mahdi
P2860cites workBiosynthesis of selenocysteine on its tRNA in eukaryotesQ21145895
Deletion of apolipoprotein E receptor-2 in mice lowers brain selenium and causes severe neurological dysfunction and death when a low-selenium diet is fed.Q48144238
Anterograde transport of brain-derived neurotrophic factor and its role in the brainQ48539947
Parvalbumin expression in visual cortical interneurons depends on neuronal activity and TrkB ligands during an Early period of postnatal development.Q52094146
Cholinergic regulation of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) but not neurotrophin-3 (NT-3) mRNA levels in the developing rat hippocampusQ61643509
Glutathione peroxidase deficiency and childhood seizuresQ68302817
Selenium deficiency triggering intractable seizuresQ72415592
Essential role for mitochondrial thioredoxin reductase in hematopoiesis, heart development, and heart functionQ24563493
RNA-dependent conversion of phosphoserine forms selenocysteine in eukaryotes and archaeaQ24678069
Characterization of mammalian selenoproteomes.Q27863319
Neurological dysfunction occurs in mice with targeted deletion of the selenoprotein P geneQ28508731
Cytoplasmic thioredoxin reductase is essential for embryogenesis but dispensable for cardiac developmentQ28510029
Deletion of selenoprotein P alters distribution of selenium in the mouseQ28512024
Efficient selenium transfer from mother to offspring in selenoprotein-P-deficient mice enables dose-dependent rescue of phenotypes associated with selenium deficiencyQ28512221
Secisbp2 is essential for embryonic development and enhances selenoprotein expressionQ28585049
Neuronal selenoprotein expression is required for interneuron development and prevents seizures and neurodegenerationQ28591775
Deletion of selenoprotein P results in impaired function of parvalbumin interneurons and alterations in fear learning and sensorimotor gatingQ30455381
LIM homeodomain transcription factor-dependent specification of bipotential MGE progenitors into cholinergic and GABAergic striatal interneuronsQ30491175
The syndrome of inherited partial SBP2 deficiency in humansQ33830119
12/15-lipoxygenase-derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatasesQ34115614
Mutations Disrupting Selenocysteine Formation Cause Progressive Cerebello-Cerebral AtrophyQ34169430
Interneuron dysfunction in psychiatric disordersQ34247716
Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humansQ34360195
Mutations in SECISBP2 result in abnormal thyroid hormone metabolismQ34460050
Ketamine-induced loss of phenotype of fast-spiking interneurons is mediated by NADPH-oxidaseQ34722527
Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIF-mediated cell deathQ34818662
Progressive cerebellocerebral atrophy: a new syndrome with microcephaly, mental retardation, and spastic quadriplegia.Q35443213
Early embryonic lethality caused by targeted disruption of the mouse selenocysteine tRNA gene (Trsp).Q36149734
The integrity of cholinergic basal forebrain neurons depends on expression of Nkx2-1Q36364744
Selenocysteine incorporation machinery and the role of selenoproteins in development and healthQ36557525
Cerebellar hypoplasia in mice lacking selenoprotein biosynthesis in neuronsQ37699124
Post-transcriptional control of selenoprotein biosynthesisQ38019545
Hepatically derived selenoprotein P is a key factor for kidney but not for brain selenium supplyQ41870693
Gene disruption discloses role of selenoprotein P in selenium delivery to target tissuesQ42127289
Ongoing expression of Nkx2.1 in the postnatal mouse forebrain: potential for understanding NKX2.1 haploinsufficiency in humans?Q42460091
Selenoprotein-related disease in a young girl caused by nonsense mutations in the SBP2 geneQ43054577
Redox dysregulation affects the ventral but not dorsal hippocampus: impairment of parvalbumin neurons, gamma oscillations, and related behaviors.Q43158698
Comparative analysis of selenocysteine machinery and selenoproteome gene expression in mouse brain identifies neurons as key functional sites of selenium in mammalsQ46886702
Hepatic selenoprotein P (SePP) expression restores selenium transport and prevents infertility and motor-incoordination in Sepp-knockout miceQ46931534
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectbrainQ1073
striatumQ1319792
P304page(s)67-75
P577publication date2014-08-01
P1433published inBiochemical JournalQ864221
P1476titleImpaired selenoprotein expression in brain triggers striatal neuronal loss leading to co-ordination defects in mice
P478volume462

Reverse relations

cites work (P2860)
Q47161769A selenium species in cerebrospinal fluid predicts conversion to Alzheimer's dementia in persons with mild cognitive impairment
Q53565078Effect of Dietary Selenomethionine Supplementation on Growth Performance, Tissue Se Concentration, and Blood Glutathione Peroxidase Activity in Kid Boer Goats.
Q35652974Expression of Selenoproteins Is Maintained in Mice Carrying Mutations in SECp43, the tRNA Selenocysteine 1 Associated Protein (Trnau1ap).
Q37464154Human selenoprotein P and S variant mRNAs with different numbers of SECIS elements and inferences from mutant mice of the roles of multiple SECIS elements
Q56990436Mouse Models that Target Individual Selenoproteins
Q28392715Paradoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health Implications
Q51033128Rapid polygenic response to secondary contact in a hybrid species.
Q92214353Ribosome profiling of selenoproteins in vivo reveals consequences of pathogenic Secisbp2 missense mutations
Q38495280Selenium, selenoproteins and neurodegenerative diseases.
Q28085052Selenocysteine incorporation: A trump card in the game of mRNA decay
Q50060209Selenocysteine tRNA[Ser]Sec, the Central Component of Selenoprotein Biosynthesis: Isolation, Identification, Modification, and Sequencing
Q28854286Selenoprotein T Exerts an Essential Oxidoreductase Activity That Protects Dopaminergic Neurons in Mouse Models of Parkinson's Disease
Q56990448Selenoproteins in Nervous System Development, Function and Degeneration
Q89620693Thyroid Hormone Hyposensitivity: From Genotype to Phenotype and Back
Q47656935Thyroid Hormone Metabolism Defects in a Mouse Model of SBP2 Deficiency

Search more.