Role of mitochondrial membrane permeabilization in apoptosis and cancer

scientific article published on April 2004

Role of mitochondrial membrane permeabilization in apoptosis and cancer is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1041233854
P356DOI10.1038/SJ.ONC.1207534
P2888exact matchhttps://scigraph.springernature.com/pub.10.1038/sj.onc.1207534
P698PubMed publication ID15077148
P5875ResearchGate publication ID232756226

P50authorJean-Claude MartinouQ57397069
Caroline DiveQ30119872
P2093author name stringDominic James
Judith Henry-Mowatt
P2860cites workBcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDACQ22009974
Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blockedQ24318845
Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosisQ24337576
Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosolQ24675708
A human dynamin-related protein controls the distribution of mitochondriaQ24682958
A novel, high conductance channel of mitochondria linked to apoptosis in mammalian cells and Bax expression in yeastQ24685400
Mutational analysis of Mdm1p function in nuclear and mitochondrial inheritanceQ27934935
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibitionQ28115131
Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell deathQ36365164
Bcl-2 inhibits the mitochondrial release of an apoptogenic proteaseQ36367392
Bcl-xL antisense oligonucleotides radiosensitise colon cancer cellsQ36671167
A new selective AKT pharmacological inhibitor reduces resistance to chemotherapeutic drugs, TRAIL, all-trans-retinoic acid, and ionizing radiation of human leukemia cellsQ40562808
Heat shock protein 70 binding inhibits the nuclear import of apoptosis-inducing factor.Q40626779
Mitochondrial aggregation precedes cytochrome c release from mitochondria during apoptosisQ40639566
Cytokine-induced apoptosis and necrosis are preceded by disruption of the mitochondrial membrane potential (Deltapsi(m)) in pancreatic RINm5F cells: prevention by Bcl-2.Q40733537
Increased hexokinase activity, of either ectopic or endogenous origin, protects renal epithelial cells against acute oxidant-induced cell deathQ40761816
Regulation of apoptotic protease activating factor-1 oligomerization and apoptosis by the WD-40 repeat regionQ40941506
The release of cytochrome c from mitochondria during apoptosis of NGF-deprived sympathetic neurons is a reversible eventQ41837258
Membrane perturbations induced by the apoptotic Bax proteinQ43002332
Bax oligomerization in mitochondrial membranes requires tBid (caspase-8-cleaved Bid) and a mitochondrial protein.Q43002476
Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cellsQ43514949
Ectopic overexpression of second mitochondria-derived activator of caspases (Smac/DIABLO) or cotreatment with N-terminus of Smac/DIABLO peptide potentiates epothilone B derivative-(BMS 247550) and Apo-2L/TRAIL-induced apoptosisQ43966232
The apoptotic protein tBid promotes leakage by altering membrane curvatureQ44039942
Synthetic Smac/DIABLO peptides enhance the effects of chemotherapeutic agents by binding XIAP and cIAP1 in situQ44129457
Cytochrome c release precedes mitochondrial membrane potential loss in cerebellar granule neuron apoptosis: lack of mitochondrial swellingQ44163190
Conformational change and mitochondrial translocation of Bax accompany proteasome inhibitor-induced apoptosis of chronic lymphocytic leukemic cells.Q44429639
The chemopreventive agent N-(4-hydroxyphenyl)retinamide induces apoptosis through a mitochondrial pathway regulated by proteins from the Bcl-2 familyQ44588827
Adenoviral Bid overexpression induces caspase-dependent cleavage of truncated Bid and p53-independent apoptosis in human non-small cell lung cancersQ46938548
Proteasome inhibitor-induced apoptosis of glioma cells involves the processing of multiple caspases and cytochrome c release.Q52541546
Cytochrome c nitration by peroxynitrite.Q54054863
Bax-mediated Ca2+ mobilization promotes cytochrome c release during apoptosisQ64378995
Human ovarian cancer and cisplatin resistance: possible role of inhibitor of apoptosis proteinsQ64380181
Radical initiated alpha-tocopherol depletion and lipid peroxidation in mitochondrial membranesQ69337444
Inhibition of proliferation and induction of apoptosis by abrogation of heat-shock protein (HSP) 70 expression in tumor cellsQ72611142
Oxidative stress and apoptosisQ74341665
Direct evidence for membrane pore formation by the apoptotic protein BaxQ78482340
Mammalian caspases: structure, activation, substrates, and functions during apoptosisQ28139429
A structural view of mitochondria-mediated apoptosisQ28185843
Endonuclease G is an apoptotic DNase when released from mitochondriaQ28206238
hFis1, a novel component of the mammalian mitochondrial fission machineryQ28208369
Death and anti-death: tumour resistance to apoptosisQ28217065
WD-40 repeat region regulates Apaf-1 self-association and procaspase-9 activationQ28290389
Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and deathQ28363890
Recombinant expression of the voltage-dependent anion channel enhances the transfer of Ca2+ microdomains to mitochondriaQ28565012
Cytochrome c release from mitochondria proceeds by a two-step processQ28571562
Endonuclease G is required for early embryogenesis and normal apoptosis in miceQ28585337
Mitochondria and apoptosisQ29547905
NF-kappaB in cancer: from innocent bystander to major culpritQ29614603
Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membraneQ29616354
The Bcl-2 protein family: arbiters of cell survivalQ29618158
Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeuticsQ29620467
Mitochondrial binding of hexokinase II inhibits Bax-induced cytochrome c release and apoptosis.Q30167710
Does nitric oxide modulate mitochondrial energy generation and apoptosis?Q34127186
The 'harmless' release of cytochrome c.Q34139341
Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocationQ34245495
C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2.Q34322094
Spatio-temporal organization of the mitochondrial phase of apoptosisQ34499125
And all of a sudden it's over: mitochondrial outer-membrane permeabilization in apoptosisQ34648801
The permeability transition pore complex: another view.Q34648839
The Apaf-1 apoptosome: a large caspase-activating complexQ34648882
Chemotherapy: targeting the mitochondrial cell death pathwayQ35026496
Mitochondrial permeability transition: a common pathway to necrosis and apoptosisQ35120719
The mitochondrial membrane potential (deltapsi(m)) in apoptosis; an updateQ35135739
The histone deacetylase inhibitor suberic bishydroxamate: a potential sensitizer of melanoma to TNF-related apoptosis-inducing ligand (TRAIL) induced apoptosis.Q35557641
Alterations in the apoptotic machinery and their potential role in anticancer drug resistanceQ35567264
The role of p53 in chemosensitivity and radiosensitivity.Q35567279
Bcl-2 decreases the free Ca2+ concentration within the endoplasmic reticulumQ35745275
Preservation of mitochondrial structure and function after Bid- or Bax-mediated cytochrome c releaseQ36328615
Caspase inhibition extends the commitment to neuronal death beyond cytochrome c release to the point of mitochondrial depolarizationQ36342515
Bax and Bak coalesce into novel mitochondria-associated clusters during apoptosisQ36364894
P433issue16
P407language of work or nameEnglishQ1860
P921main subjectapoptotic processQ14599311
P304page(s)2850-2860
P577publication date2004-04-01
P1433published inOncogeneQ1568657
P1476titleRole of mitochondrial membrane permeabilization in apoptosis and cancer
P478volume23

Reverse relations

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