The effects of thymic selection on the range of T cell cross-reactivity

scientific article published on December 2005

The effects of thymic selection on the range of T cell cross-reactivity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/EJI.200535098
P932PMC publication ID1857316
P698PubMed publication ID16285012
P5875ResearchGate publication ID7483410

P50authorDennis L ChaoQ55441873
Alan S. PerelsonQ55719625
Miles DavenportQ58417655
P2093author name stringStephanie Forrest
P2860cites workPositive selection of HIV-1 cytotoxic T lymphocyte escape variants during primary infectionQ24564779
T-cell antigen receptor genes and T-cell recognitionQ29619721
Molecular basis for recognition of an arthritic peptide and a foreign epitope on distinct MHC molecules by a single TCR.Q30872493
TCRs with high affinity for foreign pMHC show self-reactivityQ30873107
Explaining high alloreactivity as a quantitative consequence of affinity-driven thymocyte selectionQ33333657
Selecting and maintaining a diverse T-cell repertoireQ33783983
A direct estimate of the human alphabeta T cell receptor diversityQ33878476
Self-tolerance: context dependent tuning of T cell antigen recognitionQ33980399
Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic proteinQ34293468
The MHC reactivity of the T cell repertoire prior to positive and negative selection.Q34418401
The specificity of TCR/pMHC interactionQ34493013
Quantitative constraints on the scope of negative selectionQ35077155
Role of self-peptides in positively selecting the T-cell repertoireQ59080090
T-cell apoptosis detected in situ during positive and negative selection in the thymusQ59087078
Peptide contributes to the specificity of positive selection of CD8+ T cells in the thymusQ63363368
Positive and negative thymocyte selection induced by different concentrations of a single peptideQ72293139
Quantitative constraints on the scope of negative selection: robustness and weaknessesQ73275221
Selection of a Broad Repertoire of CD4+ T Cells in H-2Ma0/0 MiceQ73669902
A very high level of crossreactivity is an essential feature of the T-cell receptorQ77324273
Crossreactivity of the T-cell receptorQ77324297
Predicting the size of the T-cell receptor and antibody combining region from consideration of efficient self-nonself discriminationQ36124837
Negative selection imparts peptide specificity to the mature T cell repertoireQ36161289
Dynamic tuning of T cell reactivity by self-peptide-major histocompatibility complex ligandsQ36369018
Quantitative impact of thymic clonal deletion on the T cell repertoireQ36376530
How Many Thymocytes Audition for Selection?Q36380676
HIV-specific cytotoxic T cells from long-term survivors select a unique T cell receptorQ36399832
Adaptive cellular interactions in the immune system: the tunable activation threshold and the significance of subthreshold responsesQ37277286
In vitro selection of lymphocytic choriomeningitis virus escape mutants by cytotoxic T lymphocytesQ37640068
The generation and fate of thymocytesQ37836693
A biological role for the major histocompatibility antigensQ39333074
Alpha beta TCRs differ in the degree of their specificity for the positively selecting MHC/peptide ligandQ40729106
Positive selection of lymphocytesQ40807424
The role of the T cell receptor in positive and negative selection of developing T cellsQ41174331
T-cell-receptor affinity and thymocyte positive selectionQ41192128
In Thymic Selection, Peptide Diversity Gives and Takes AwayQ41585792
Use of global amino acid replacements to define the requirements for MHC binding and T cell recognition of moth cytochrome c (93-103).Q42068640
Thymic selection by a single MHC/peptide ligand produces a semidiverse repertoire of CD4+ T cells.Q43484431
Evidence for a differential avidity model of T cell selection in the thymusQ45155438
Preferential escape of subdominant CD8+ T cells during negative selection results in an altered antiviral T cell hierarchyQ45857950
Viral escape by selection of cytotoxic T cell-resistant virus variants in vivoQ45860175
Activation-threshold tuning in an affinity model for the T-cell repertoireQ51997239
Thymic selection does not limit the individual MHC diversityQ52007589
A quantitative theory of affinity-driven T cell repertoire selectionQ52141407
The repertoire of T cells shaped by a single MHC/peptide ligand.Q52887226
Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system.Q55061347
How the T Cell Repertoire Becomes Peptide and MHC SpecificQ56922033
T cell tolerance by clonal elimination in the thymusQ56922465
Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytesQ57075675
A stochastic model of cytotoxic T cell responsesQ57213454
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)3452-3459
P577publication date2005-12-01
P1433published inEuropean Journal of ImmunologyQ5412727
P1476titleThe effects of thymic selection on the range of T cell cross-reactivity
P478volume35

Reverse relations

cites work (P2860)
Q36762544Computer immunology
Q34994754Effects of thymic selection of the T-cell repertoire on HLA class I-associated control of HIV infection
Q47569621Effects of thymic selection on T cell recognition of foreign and tumor antigenic peptides.
Q36954931How the thymus designs antigen-specific and self-tolerant T cell receptor sequences
Q34487794Mapping the landscape of host-pathogen coevolution: HLA class I binding and its relationship with evolutionary conservation in human and viral proteins.
Q34916448Models of Self-Peptide Sampling by Developing T Cells Identify Candidate Mechanisms of Thymic Selection
Q42406349Positive and negative selection, self-nonself discrimination and the roles of costimulation and anergy
Q51631028Predicting interactions between T cell receptors and MHC-peptide complexes
Q59062745The Influence of T Cell Development on Pathogen Specificity and Autoreactivity
Q37551442Theories and quantification of thymic selection
Q59063074Thymic Selection of T-Cell Receptors as an Extreme Value Problem

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