PRMT5 and the role of symmetrical dimethylarginine in chromatoid bodies of planarian stem cells.

scientific article published on 8 February 2012

PRMT5 and the role of symmetrical dimethylarginine in chromatoid bodies of planarian stem cells. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1242/DEV.076182
P932PMC publication ID3283120
P698PubMed publication ID22318224
P5875ResearchGate publication ID221817189

P50authorPhillip NewmarkQ30323432
P2093author name stringLabib Rouhana
Ana P Vieira
Rachel H Roberts-Galbraith
P2860cites workRegeneration and pattern formation in planarians. I. The pattern of mitosis in anterior and posterior regeneration in Dugesia (G) tigrina, and a new proposal for blastema formationQ70677689
Mitosis in normal and regenerating planariansQ72108345
Electron microscopic studies of planarian regeneration. I. Fine structure of neoblasts in Dugesia dorotocephalaQ72350566
The structure of mammalian small nuclear ribonucleoproteins. Identification of multiple protein components reactive with anti-(U1)ribonucleoprotein and anti-Sm autoantibodiesQ72812865
PLASTIC EMBEDDING MIXTURES FOR USE IN ELECTRON MICROSCOPYQ76747378
Smed-SmB, a member of the LSm protein superfamily, is essential for chromatoid body organization and planarian stem cell proliferationQ83160892
Symmetrical dimethylation of arginine residues in spliceosomal Sm protein B/B' and the Sm-like protein LSm4, and their interaction with the SMN protein.Q24540057
The methylosome, a 20S complex containing JBP1 and pICln, produces dimethylarginine-modified Sm proteinsQ24548244
Structural basis for recognition of arginine methylated Piwi proteins by the extended Tudor domainQ24615547
PGL proteins self associate and bind RNPs to mediate germ granule assembly in C. elegansQ24632882
RNA-seq: an assessment of technical reproducibility and comparison with gene expression arraysQ24655562
Genome-wide analyses reveal a role for peptide hormones in planarian germline developmentQ27323116
SMN tudor domain structure and its interaction with the Sm proteinsQ27629094
High-resolution X-ray and NMR structures of the SMN Tudor domain: conformational variation in the binding site for symmetrically dimethylated arginine residuesQ27640685
Structural basis for methylarginine-dependent recognition of Aubergine by TudorQ27664064
Edc3p and a glutamine/asparagine-rich domain of Lsm4p function in processing body assembly in Saccharomyces cerevisiaeQ27930894
A role for Q/N-rich aggregation-prone regions in P-body localization.Q27932050
The C-terminal RG dipeptide repeats of the spliceosomal Sm proteins D1 and D3 contain symmetrical dimethylarginines, which form a major B-cell epitope for anti-Sm autoantibodiesQ28140527
Methylation of Sm proteins by a complex containing PRMT5 and the putative U snRNP assembly factor pIClnQ28211723
Cytoplasmic compartmentalization of the fetal piRNA pathway in miceQ28507656
Loss of the Mili-interacting Tudor domain-containing protein-1 activates transposons and alters the Mili-associated small RNA profileQ28511307
The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germlineQ28585476
TDRD5 is required for retrotransposon silencing, chromatoid body assembly, and spermiogenesis in miceQ28588119
Tdrd6 is required for spermiogenesis, chromatoid body architecture, and regulation of miRNA expressionQ28593820
PIWI-interacting small RNAs: the vanguard of genome defenceQ29614712
Monoclonal antibodies to nucleic acid-containing cellular constituents: probes for molecular biology and autoimmune diseaseQ29616423
The Schmidtea mediterranea database as a molecular resource for studying platyhelminthes, stem cells and regenerationQ31117991
Retrotransposon silencing by piRNAs: ping-pong players mark their sub-cellular boundariesQ33518480
Functional involvement of Tudor and dPRMT5 in the piRNA processing pathway in Drosophila germlinesQ33553009
A planarian p53 homolog regulates proliferation and self-renewal in adult stem cell lineagesQ33561621
Arginine methylation of Aubergine mediates Tudor binding and germ plasm localizationQ33572966
Arginine methylation of SmB is required for Drosophila germ cell developmentQ42957617
An insulin-like peptide regulates size and adult stem cells in planariansQ43996192
A mortalin-like gene is crucial for planarian stem cell viabilityQ44204690
Somatic stem cells express Piwi and Vasa genes in an adult ctenophore: ancient association of "germline genes" with stemnessQ45191219
Chromatoid bodies in somatic cells of the planarian: observations on their behavior during mitosisQ45277292
RNA and Protein Interactions Modulated by Protein Arginine MethylationQ46021819
The role of Tudor domains in germline development and polar granule architectureQ47070085
Arginine methyltransferase Capsuleen is essential for methylation of spliceosomal Sm proteins and germ cell formation in Drosophila.Q47071167
The Sm-protein methyltransferase, dart5, is essential for germ-cell specification and maintenance.Q47072191
Drosophila tudor is essential for polar granule assembly and pole cell specification, but not for posterior patterningQ47072339
Expression of vasa(vas)-related genes in germline cells and totipotent somatic stem cells of planariansQ47992595
A Bruno-like gene is required for stem cell maintenance in planariansQ48085602
SMEDWI-2 is a PIWI-like protein that regulates planarian stem cellsQ48111456
The C-terminus of the yeast Lsm4p is required for the association to P-bodiesQ50664448
Piwi expression in archeocytes and choanocytes in demosponges: insights into the stem cell system in demosponges.Q51905964
Different requirements for conserved post-transcriptional regulators in planarian regeneration and stem cell maintenanceQ51912877
DjCBC-1, a conserved DEAD box RNA helicase of the RCK/p54/Me31B family, is a component of RNA-protein complexes in planarian stem cells and neuronsQ51972700
smedinx-11 is a planarian stem cell gap junction gene required for regeneration and homeostasisQ51979505
Vasa unveils a common origin of germ cells and of somatic stem cells from the posterior growth zone in the polychaete Platynereis dumeriliiQ51987574
Planarian homologs of netrin and netrin receptor are required for proper regeneration of the central nervous system and the maintenance of nervous system architectureQ52043748
tudor, a gene required for assembly of the germ plasm in Drosophila melanogasterQ52264942
Immunoprecipitation of piRNPs and directional, next generation sequencing of piRNAs.Q52719549
Role of c-Jun N-terminal kinase activation in blastema formation during planarian regenerationQ53258059
Stem cells are differentially regulated during development, regeneration and homeostasis in flatwormsQ53381618
An RbAp48-like gene regulates adult stem cells in planariansQ54443583
ERK signaling controls blastema cell differentiation during planarian regeneration.Q54587673
DjPiwi-1, a member of the PAZ-Piwi gene family, defines a subpopulation of planarian stem cells.Q54614095
Distribution of the stem cells (neoblasts) in the planarian Dugesia japonica.Q54684647
Bromodeoxyuridine Specifically Labels the Regenerative Stem Cells of PlanariansQ58632945
Identification and origin of the germline stem cells as revealed by the expression of nanos-related gene in planariansQ61447953
Fine structure studies on the planarian, Dugesia. I. Nature of the "neoblast" and other cell types in noninjured wormsQ66910234
Stage-specific expression of three cell surface carbohydrate antigens during murine spermatogenesis detected with monoclonal antibodiesQ70338985
???Q94724584
???Q94768422
Launching the germline in Caenorhabditis elegans: regulation of gene expression in early germ cells.Q33678631
Arginine methylation of vasa protein is conserved across phylaQ33707074
How does the royal family of Tudor rule the PIWI-interacting RNA pathway?Q33767860
Sm proteins specify germ cell fate by facilitating oskar mRNA localizationQ33929636
Building RNA-protein granules: insight from the germlineQ34087911
Not your father's planarian: a classic model enters the era of functional genomics.Q34125141
A functional genomic screen in planarians identifies novel regulators of germ cell developmentQ34127490
Clonogenic Neoblasts Are Pluripotent Adult Stem Cells That Underlie Planarian RegenerationQ34184695
The planarian Schmidtea mediterranea as a model for epigenetic germ cell specification: analysis of ESTs from the hermaphroditic strainQ34234893
A conserved germline multipotency programQ34342503
Arginine methylation as a molecular signature of the Piwi small RNA pathwayQ34357395
Tudor domains bind symmetrical dimethylated argininesQ34426427
Pathway to totipotency: lessons from germ cellsQ34585032
P granules extend the nuclear pore complex environment in the C. elegans germ lineQ34712466
RNA granules in germ cellsQ35578422
nanos function is essential for development and regeneration of planarian germ cells.Q35749561
Stem cell-based growth, regeneration, and remodeling of the planarian intestineQ36375720
SmedGD: the Schmidtea mediterranea genome databaseQ36454142
The PIWI proteins SMEDWI-2 and SMEDWI-3 are required for stem cell function and piRNA expression in planarians.Q36666293
How selfish retrotransposons are silenced in Drosophila germline and somatic cellsQ37197624
High-resolution profiling and discovery of planarian small RNAs.Q37245059
Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family membersQ37287579
Germ cell specification and regeneration in planarians.Q37331019
Arginine methylation of Piwi proteins catalysed by dPRMT5 is required for Ago3 and Aub stabilityQ37352427
The stem cell system in demosponges: insights into the origin of somatic stem cells.Q37676279
Cellular and molecular dissection of pluripotent adult somatic stem cells in planarians.Q37676282
DjPum, a homologue of Drosophila Pumilio, is essential to planarian stem cell maintenanceQ38329325
The Mi-2-like Smed-CHD4 gene is required for stem cell differentiation in the planarian Schmidtea mediterraneaQ39849555
Regulation of synaptic Pumilio function by an aggregation-prone domainQ39850673
A SIMPLIFIED LEAD CITRATE STAIN FOR USE IN ELECTRON MICROSCOPY.Q41066255
PRMT1 is the predominant type I protein arginine methyltransferase in mammalian cellsQ41724415
Spoltud-1 is a chromatoid body component required for planarian long-term stem cell self-renewalQ41780026
Identification of genes needed for regeneration, stem cell function, and tissue homeostasis by systematic gene perturbation in planariaQ41868332
Molecular analysis of stem cells and their descendants during cell turnover and regeneration in the planarian Schmidtea mediterraneaQ41922401
Formaldehyde-based whole-mount in situ hybridization method for planariansQ41947311
Mili interacts with tudor domain-containing protein 1 in regulating spermatogenesisQ42254602
Planarian regeneration involves distinct stem cell responses to wounds and tissue absenceQ42413468
The germ line and somatic stem cell gene Cniwi in the jellyfish Podocoryne carneaQ42458158
Germ line determinants are not localized early in sea urchin development, but do accumulate in the small micromere lineage.Q42501352
Developmental biology. Versatile germline genesQ42727052
P433issue6
P407language of work or nameEnglishQ1860
P1104number of pages12
P304page(s)1083-1094
P577publication date2012-02-08
P1433published inDevelopmentQ3025404
P1476titlePRMT5 and the role of symmetrical dimethylarginine in chromatoid bodies of planarian stem cells
P478volume139

Reverse relations

cites work (P2860)
Q37321625A functional genomics screen in planarians reveals regulators of whole-brain regeneration.
Q34619926A lophotrochozoan-specific nuclear hormone receptor is required for reproductive system development in the planarian.
Q36906738A sex-specific transcription factor controls male identity in a simultaneous hermaphrodite
Q47687611Analysis of Hydra PIWI proteins and piRNAs uncover early evolutionary origins of the piRNA pathway
Q52576606Cell type transcriptome atlas for the planarian Schmidtea mediterranea.
Q37162242Conserved functional antagonism of CELF and MBNL proteins controls stem cell-specific alternative splicing in planarians
Q30946349Digital gene expression approach over multiple RNA-Seq data sets to detect neoblast transcriptional changes in Schmidtea mediterranea
Q30837695Embryonic origin of adult stem cells required for tissue homeostasis and regeneration.
Q46249270EvoRegen in Animals: Time to uncover deep conservation or convergence of adult stem cell evolution and regenerative processes
Q36567739Follistatin antagonizes activin signaling and acts with notum to direct planarian head regeneration.
Q34986869Generation of cell type-specific monoclonal antibodies for the planarian and optimization of sample processing for immunolabeling
Q41258679Genetic dissection of the planarian reproductive system through characterization of Schmidtea mediterranea CPEB homologs
Q48376360Genetic expansion of chaperonin-containing TCP-1 (CCT/TRiC) complex subunits yields testis-specific isoforms required for spermatogenesis in planarian flatworms.
Q27308881Germline Defects Caused by Smed-boule RNA-Interference Reveal That Egg Capsule Deposition Occurs Independently of Fertilization, Ovulation, Mating, or the Presence of Gametes in Planarian Flatworms
Q42008240Girardia dorotocephala transcriptome sequence, assembly, and validation through characterization of piwi homologs and stem cell progeny markers
Q46598761Heterogeneity of chromatoid bodies in adult pluripotent stem cells of planarian Dugesia japonica
Q30538111In situ hybridization protocol for enhanced detection of gene expression in the planarian Schmidtea mediterranea
Q48167264Light and electron microscopic studies of the intestinal epithelium in Notoplana humilis (Platyhelminthes, Polycladida): the contribution of mesodermal/gastrodermal neoblasts to intestinal regeneration.
Q37714522Molecular cloning and characterization of SL3: a stem cell-specific SL RNA from the planarian Schmidtea mediterranea
Q42062049Molecular signatures that correlate with induction of lens regeneration in newts: lessons from proteomic analysis
Q88107247Neoblast-enriched zinc finger protein FIR1 triggers local proliferation during planarian regeneration
Q27015738Next generation organelles: Structure and role of germ granules in the germline
Q33796234PIWI homologs mediate histone H4 mRNA localization to planarian chromatoid bodies
Q34602255PRMT5 protects genomic integrity during global DNA demethylation in primordial germ cells and preimplantation embryos
Q26823327Piwi and potency: PIWI proteins in animal stem cells and regeneration
Q35844590PlanMine--a mineable resource of planarian biology and biodiversity
Q47304367PlanNET: Homology-based predicted interactome for multiple planarian transcriptomes
Q90182275Planarians recruit piRNAs for mRNA turnover in adult stem cells
Q33898380Preparation of the planarian Schmidtea mediterranea for high-resolution histology and transmission electron microscopy
Q38224097Prohibitin 2 regulates cell proliferation and mitochondrial cristae morphogenesis in planarian stem cells
Q35564194Protein expression profiling in head fragments during planarian regeneration after amputation
Q41905469RNA interference by feeding in vitro–synthesized double‐stranded RNA to planarians: Methodology and dynamics
Q37185632Regulation of constitutive and alternative splicing by PRMT5 reveals a role for Mdm4 pre-mRNA in sensing defects in the spliceosomal machinery
Q37265398Restoration of anterior regeneration in a planarian with limited regenerative ability
Q28602777SmedGD 2.0: The Schmidtea mediterranea genome database
Q26829049Specialized progenitors and regeneration
Q36554663Stem cell systems and regeneration in planaria
Q27676657Structure of the Arginine Methyltransferase PRMT5-MEP50 Reveals a Mechanism for Substrate Specificity
Q92373773Tau tubulin kinase is required for spermatogenesis and development of motile cilia in planarian flatworms
Q27318426The CCR4-NOT complex mediates deadenylation and degradation of stem cell mRNAs and promotes planarian stem cell differentiation
Q28655577The biology of the germ line in echinoderms
Q90308460The exon junction complex is required for stem and progenitor cell maintenance in planarians
Q38116923The history and enduring contributions of planarians to the study of animal regeneration.
Q38051058The stem cell system in demosponges: suggested involvement of two types of cells: archeocytes (active stem cells) and choanocytes (food-entrapping flagellated cells).
Q36619289Towards a bioinformatics of patterning: a computational approach to understanding regulative morphogenesis
Q107750894Ultrastructure of Neoblasts in Turbellarian Geocentrophora wagini Timoshkin, 1984 (Lecithoepitheliata: Plathelminthes)

Search more.