Biological channeling of a reactive intermediate in the bifunctional enzyme DmpFG.

scientific article published on 21 February 2012

Biological channeling of a reactive intermediate in the bifunctional enzyme DmpFG. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.BPJ.2012.01.029
P932PMC publication ID3283820
P698PubMed publication ID22385858
P5875ResearchGate publication ID221884271

P50authorBen CorryQ41048411
Alice VrielinkQ57064314
P2093author name stringNatalie E Smith
Paul V Attwood
P2860cites workPurification and properties of the physically associated meta-cleavage pathway enzymes 4-hydroxy-2-ketovalerate aldolase and aldehyde dehydrogenase (acylating) from Pseudomonas sp. strain CF600Q24672183
Crystal structure of a bifunctional aldolase-dehydrogenase: sequestering a reactive and volatile intermediateQ24680858
Nucleotide sequence and functional analysis of the complete phenol/3,4-dimethylphenol catabolic pathway of Pseudomonas sp. strain CF600Q24684543
A Ni-Fe-Cu center in a bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthaseQ27639843
Ni-Zn-[Fe4-S4] and Ni-Ni-[Fe4-S4] clusters in closed and open subunits of acetyl-CoA synthase/carbon monoxide dehydrogenaseQ27640664
Coupled formation of an amidotransferase interdomain ammonia channel and a phosphoribosyltransferase active siteQ27745868
All-atom empirical potential for molecular modeling and dynamics studies of proteinsQ27860468
VMD: visual molecular dynamicsQ27860554
Scalable molecular dynamics with NAMDQ27860718
Tunneling of intermediates in enzyme-catalyzed reactionsQ28259892
The molecular basis of substrate channelingQ33598946
Channeling of substrates and intermediates in enzyme-catalyzed reactionsQ33950245
Complexes of sequential metabolic enzymesQ34039557
Escaping free-energy minimaQ34151010
Characterization of an aldolase-dehydrogenase complex that exhibits substrate channeling in the polychlorinated biphenyls degradation pathway.Q34983462
Comparison of two metal-dependent pyruvate aldolases related by convergent evolution: substrate specificity, kinetic mechanism, and substrate channelingQ43109869
Electrostatic channeling in the bifunctional enzyme dihydrofolate reductase-thymidylate synthaseQ44097587
Investigating the molecular determinants for substrate channeling in BphI-BphJ, an aldolase-dehydrogenase complex from the polychlorinated biphenyls degradation pathway.Q45922898
Evidence for electrostatic channeling in a fusion protein of malate dehydrogenase and citrate synthaseQ46632258
Mechanism for the transport of ammonia within carbamoyl phosphate synthetase determined by molecular dynamics simulationsQ46791308
Probing the molecular basis of substrate specificity, stereospecificity, and catalysis in the class II pyruvate aldolase, BphI.Q53259775
Aldehyde dehydrogenase catalytic mechanism. A proposalQ77824799
P433issue4
P407language of work or nameEnglishQ1860
P1104number of pages10
P304page(s)868-877
P577publication date2012-02-21
P1433published inBiophysical JournalQ2032955
P1476titleBiological channeling of a reactive intermediate in the bifunctional enzyme DmpFG
P478volume102

Reverse relations

cites work (P2860)
Q30361434Binding and channeling of alternative substrates in the enzyme DmpFG: a molecular dynamics study.
Q61444627Can enzyme proximity accelerate cascade reactions?
Q36289808Does metabolite channeling accelerate enzyme-catalyzed cascade reactions?
Q37563541Evidence for hysteretic substrate channeling in the proline dehydrogenase and Δ1-pyrroline-5-carboxylate dehydrogenase coupled reaction of proline utilization A (PutA).
Q58105665The multicatalytic compartment of propionyl-CoA synthase sequesters a toxic metabolite
Q50870496Tying the knot: occurrence and possible significance of gene fusions in plant metabolism and beyond.

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