Sea anemone venom as a source of insecticidal peptides acting on voltage-gated Na+ channels.

scientific article published on 5 December 2006

Sea anemone venom as a source of insecticidal peptides acting on voltage-gated Na+ channels. is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1016/J.TOXICON.2006.11.029
P932PMC publication ID1868498
P698PubMed publication ID17224168
P5875ResearchGate publication ID6578415

P50authorJan TytgatQ13735914
Frank BosmansQ59662440
P2860cites workOverview of the voltage-gated sodium channel familyQ21999779
Sodium channel beta4, a new disulfide-linked auxiliary subunit with similarity to beta2Q24317249
Phylogenetic analysis of arthropods using two nuclear protein-encoding genes supports a crustacean + hexapod cladeQ24671012
Three-dimensional structure of the neurotoxin ATX Ia from Anemonia sulcata in aqueous solution determined by nuclear magnetic resonance spectroscopyQ27698414
Solution structure of the cardiostimulant polypeptide anthopleurin-B and comparison with anthopleurin-AQ27729725
Three-dimensional structure in solution of neurotoxin III from the sea anemone Anemonia sulcataQ27730199
Refined structure in solution of the sea anemone neurotoxin ShIQ27730435
Nomenclature of voltage-gated sodium channelsQ28141860
Scorpion toxins specific for Na+-channelsQ28144635
Hexapod origins: monophyletic or paraphyletic?Q28185439
Characterization of two Bunodosoma granulifera toxins active on cardiac sodium channelsQ28363715
Functional expression of Drosophila para sodium channels. Modulation by the membrane protein TipE and toxin pharmacologyQ28379056
AaIT: from neurotoxin to insecticideQ33925841
The sea anemone Bunodosoma granulifera contains surprisingly efficacious and potent insect-selective toxins.Q34161908
Binding specificity of sea anemone toxins to Nav 1.1-1.6 sodium channels: unexpected contributions from differences in the IV/S3-S4 outer loop.Q34323654
Isolation and molecular cloning of novel peptide toxins from the sea anemone Antheopsis maculataQ34373915
Purification, sequence, and pharmacological properties of sea anemone toxins from Radianthus paumotensis. A new class of sea anemone toxins acting on the sodium channelQ34377655
Molecular determinants of high affinity binding of alpha-scorpion toxin and sea anemone toxin in the S3-S4 extracellular loop in domain IV of the Na+ channel alpha subunitQ34384573
Halcurin, a polypeptide toxin from the sea anemone Halcurias sp., with a structural resemblance to type 1 and 2 toxinsQ34424513
Recombinant baculoviruses for insect controlQ34429121
Molecular interaction of delta-conotoxins with voltage-gated sodium channels.Q34430245
Sea anemone peptides with a specific blocking activity against the fast inactivating potassium channel Kv3.4.Q34460784
Peptide toxins in sea anemones: structural and functional aspectsQ34478906
Voltage-gated sodium channels as primary targets of diverse lipid-soluble neurotoxinsQ34529515
A new toxin from the sea anemone Condylactis gigantea with effect on sodium channel inactivation.Q34543540
Structure and structure-function relationships of sea anemone proteins that interact with the sodium channelQ34550953
The molecular biology of knockdown resistance to pyrethroid insecticidesQ35138012
Voltage-gated sodium channel toxins: poisons, probes, and future promiseQ35141466
Structure and function of delta-atracotoxins: lethal neurotoxins targeting the voltage-gated sodium channel.Q35739174
A new sea anemone peptide, APETx2, inhibits ASIC3, a major acid-sensitive channel in sensory neuronsQ37544583
Importance of the unique cationic residues arginine 12 and lysine 49 in the activity of the cardiotonic polypeptide anthopleurin B.Q38312254
Leucine 18, a hydrophobic residue essential for high affinity binding of anthopleurin B to the voltage-sensitive sodium channel.Q38358890
Isolation and characterisation of three polypeptides with neurotoxic activity from Anemonia sulcataQ40308754
Further enhancement of baculovirus insecticidal efficacy with scorpion toxins that interact cooperatively.Q40668174
The insect voltage-gated sodium channel as target of insecticidesQ40824111
Development of recombinant viral insecticides by expression of an insect-specific toxin and insect-specific enzyme in nuclear polyhedrosis virusesQ40893978
A specific interaction between the cardiac sodium channel and site-3 toxin anthopleurin B.Q41067774
Purification and pharmacological properties of eight sea anemone toxins from Anemonia sulcata, Anthopleura xanthogrammica, Stoichactis giganteus and Actinodendron plumosumQ41468516
Primary and secondary structure of a pore-forming toxin from the sea anemone, Actinia equina L., and its association with lipid vesiclesQ44489856
Actions of three structurally distinct sea anemone toxins on crustacean and insect sodium channelsQ44548362
Combinatorial interaction of scorpion toxins Lqh-2, Lqh-3, and LqhalphaIT with sodium channel receptor sites-3.Q44772923
Role of Asn-16 and Ser-19 in anthopleurin B binding. Implications for the electrostatic nature of Na(V) site 3.Q44915864
Identification of amino acid residues in the insect sodium channel critical for pyrethroid bindingQ45138703
Cloning and functional analysis of TipE, a novel membrane protein that enhances Drosophila para sodium channel functionQ47072615
Binding of an alpha scorpion toxin to insect sodium channels is not dependent on membrane potentialQ48348008
The voltage-dependent Na+ channel of insect nervous system identified by receptor sites for tetrodotoxin, and scorpion and sea anemone toxinsQ48452145
The sea anemone toxins BgII and BgIII prolong the inactivation time course of the tetrodotoxin-sensitive sodium current in rat dorsal root ganglion neurons.Q49012140
Scorpion toxins affecting sodium current inactivation bind to distinct homologous receptor sites on rat brain and insect sodium channelsQ49012937
Expression and mutagenesis of the sea anemone toxin Av2 reveals key amino acid residues important for activity on voltage-gated sodium channels.Q50646995
Structural basis for the voltage-gated Na+ channel selectivity of the scorpion alpha-like toxin BmK M1.Q50656863
Spider venom toxin protects plants from insect attack.Q51179840
Common features in the functional surface of scorpion beta-toxins and elements that confer specificity for insect and mammalian voltage-gated sodium channels.Q51821558
Effects of several sea anemone and scorpion toxins on excitability and ionic currents in the giant axon of the cockroachQ52515768
Toxin III from Leiurus quinquestriatus quinquestriatus: a specific probe for receptor site 3 on insect sodium channels.Q52558828
Gene translocation links insects and crustaceans.Q52563100
Orally active acaricidal peptide toxins from spider venom.Q52663054
The role of exposed tryptophan residues in the activity of the cardiotonic polypeptide anthopleurin B.Q53981963
Functional expression and characterization of four novel neurotoxins from sea anemone Anthopleura sp.Q54513962
APETx1, a new toxin from the sea anemone Anthopleura elegantissima, blocks voltage-gated human ether-a-go-go-related gene potassium channels.Q55036615
Polyvalent proteinase inhibitor from the sea anemone Anemonia sulcata: effect on coagulation and fibrinolysisQ67026927
Backbone folding of the polypeptide cardiac stimulant anthopleurin-A determined by nuclear magnetic resonance, distance geometry and molecular dynamicsQ67953710
Purification of a toxin from tentacles of the anemone Condylactis giganteaQ68732826
Amino acid sequence of a sea anemone toxin from Parasicyonis actinostoloidesQ69866377
Structure-function relationships of sea anemone toxin II from Anemonia sulcataQ72476087
Positively charged amino acid residues located similarly in sea anemone and scorpion toxinsQ72680294
Occurrence of type 3 sodium channel peptide toxins in two species of sea anemones (Dofleinia armata and Entacmaea ramsayi)Q73216975
Differences in the binding sites of two site-3 sodium channel toxinsQ73718150
Isolation and biological characterization of neurotoxic compounds from the sea anemone Lebrunia danae (Duchassaing and Michelotti, 1860)Q82538163
P433issue4
P921main subjectvoltageQ25428
insecticideQ181322
venomQ3386847
P1104number of pages11
P304page(s)550-560
P577publication date2006-12-05
P1433published inToxiconQ7830412
P1476titleSea anemone venom as a source of insecticidal peptides acting on voltage-gated Na+ channels
P478volume49

Reverse relations

cites work (P2860)
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