Synthesis of 2-deoxy-2,2-difluoro-α-maltosyl fluoride and its X-ray structure in complex with Streptomyces coelicolor GlgEI-V279S.

scientific article published on July 2015

Synthesis of 2-deoxy-2,2-difluoro-α-maltosyl fluoride and its X-ray structure in complex with Streptomyces coelicolor GlgEI-V279S. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1039/C5OB00867K
P932PMC publication ID4489993
P698PubMed publication ID26072729
P5875ResearchGate publication ID277723698

P50authorDonald R RonningQ56929923
Steven J SucheckQ56929936
P2093author name stringSandeep Thanna
Jared J Lindenberger
Vishwanath V Gaitonde
P2860cites workMolProbity: all-atom structure validation for macromolecular crystallographyQ24649111
PHENIX: a comprehensive Python-based system for macromolecular structure solutionQ24654617
Processing of X-ray diffraction data collected in oscillation modeQ26778468
Structure of Streptomyces Maltosyltransferase GlgE, a Homologue of a Genetically Validated Anti-tuberculosis TargetQ27673803
Structural Insight into How Streptomyces coelicolor Maltosyl Transferase GlgE Binds α-Maltose 1-Phosphate and Forms a Maltosyl-enzyme IntermediateQ27682734
Towards automated crystallographic structure refinement with phenix.refineQ27860678
Features and development of CootQ27861079
Self-poisoning of Mycobacterium tuberculosis by targeting GlgE in an alpha-glucan pathwayQ28486696
electronic Ligand Builder and Optimization Workbench (eLBOW): a tool for ligand coordinate and restraint generationQ29617258
Synthesis of a C-phosphonate mimic of maltose-1-phosphate and inhibition studies on Mycobacterium tuberculosis GlgE.Q33622421
Synthesis of a poly-hydroxypyrolidine-based inhibitor of Mycobacterium tuberculosis GlgEQ34361158
Dissecting conformational contributions to glycosidase catalysis and inhibitionQ38228725
Synthesis of fluorinated maltose derivatives for monitoring protein interaction by (19)F NMR.Q42092163
Synthesis and testing of 2-deoxy-2,2-dihaloglycosides as mechanism-based inhibitors of alpha-glycosidasesQ46697649
Mechanism-based inhibition of yeast alpha-glucosidase and human pancreatic alpha-amylase by a new class of inhibitors. 2-Deoxy-2,2-difluoro-alpha-glycosidesQ71824096
P433issue27
P921main subjectStreptomyces coelicolorQ2355919
P304page(s)7542-7550
P577publication date2015-07-01
P1433published inOrganic and Biomolecular ChemistryQ3355939
P1476titleSynthesis of 2-deoxy-2,2-difluoro-α-maltosyl fluoride and its X-ray structure in complex with Streptomyces coelicolor GlgEI-V279S.
P478volume13

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cites work (P2860)
Q35922181Crystal structures of Mycobacterium tuberculosis GlgE and complexes with non-covalent inhibitors
Q38952793Designing sugar mimetics: non-natural pyranosides as innovative chemical tools
Q38291242Ligand-bound Structures and Site-directed Mutagenesis Identify the Acceptor and Secondary Binding Sites of Streptomyces coelicolor Maltosyltransferase GlgE.
Q36101325Metabolic Network for the Biosynthesis of Intra- and Extracellular α-Glucans Required for Virulence of Mycobacterium tuberculosis
Q64232292Promising Recent Strategies with Potential Clinical Translational Value to Combat Antibacterial Resistant Surge
Q36330392Structure of Mycobacterium thermoresistibile GlgE defines novel conformational states that contribute to the catalytic mechanism
Q36629840Targeting the trehalose utilization pathways of Mycobacterium tuberculosis
Q50203520Zwitterionic pyrrolidene-phosphonates: inhibitors of the glycoside hydrolase-like phosphorylase Streptomyces coelicolor GlgEI-V279S.

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