scholarly article | Q13442814 |
P50 | author | Jordan Raff | Q37388121 |
Nina Peel | Q57326997 | ||
P2093 | author name string | Naomi R Stevens | |
Renata Basto | |||
P2860 | cites work | The Polo kinase Plk4 functions in centriole duplication | Q24292705 |
SAS-6 defines a protein family required for centrosome duplication in C. elegans and in human cells | Q24338767 | ||
D-TACC: a novel centrosomal protein required for normal spindle function in the early Drosophila embryo | Q24602580 | ||
The de novo centriole assembly pathway in HeLa cells: cell cycle progression and centriole assembly/maturation | Q24678499 | ||
De novo formation of centrosomes in vertebrate cells arrested during S phase | Q30858324 | ||
Cell cycle progression and de novo centriole assembly after centrosomal removal in untransformed human cells | Q33269437 | ||
Centrosome aberrations: cause or consequence of cancer progression? | Q34157650 | ||
The arithmetic of centrosome biogenesis | Q34312315 | ||
Centriole assembly requires both centriolar and pericentriolar material proteins | Q34372320 | ||
Structure and expression of ubiquitin genes of Drosophila melanogaster | Q34410359 | ||
SAK/PLK4 is required for centriole duplication and flagella development | Q34472675 | ||
Flies without centrioles | Q34543650 | ||
Centrosomes and cancer: lessons from a TACC. | Q34682672 | ||
Intercellular migration of centrioles in the germarium of Drosophila melanogaster. An electron microscopic study | Q36191403 | ||
The Drosophila pericentrin-like protein is essential for cilia/flagella function, but appears to be dispensable for mitosis | Q36322473 | ||
The emerging complexity of the vertebrate cilium: new functional roles for an ancient organelle | Q36529285 | ||
Centrosome duplication: of rules and licenses | Q36769585 | ||
The C. elegans zyg-1 gene encodes a regulator of centrosome duplication with distinct maternal and paternal roles in the embryo | Q39750041 | ||
Centriole assembly in Caenorhabditis elegans | Q40265072 | ||
The centrosome and cellular organization | Q40643056 | ||
Centrosome precursors in the acentriolar mouse oocyte | Q41739937 | ||
A complementary transposon tool kit for Drosophila melanogaster using P and piggyBac | Q42045441 | ||
Mechanosensory-defective, male-sterile unc mutants identify a novel basal body protein required for ciliogenesis in Drosophila | Q42463979 | ||
Transient concentration of a gamma-tubulin-related protein with a pericentrin-related protein in the formation of basal bodies and flagella during the differentiation of Naegleria gruberi | Q42523564 | ||
Anomalous centriole configurations are detected in Drosophila wing disc cells upon Cdk1 inactivation | Q42573042 | ||
The roles of Fzy/Cdc20 and Fzr/Cdh1 in regulating the destruction of cyclin B in space and time | Q42917794 | ||
The origin of centrosomes in parthenogenetic hymenopteran insects | Q44605123 | ||
Sequential protein recruitment in C. elegans centriole formation | Q47068790 | ||
The Caenorhabditis elegans centrosomal protein SPD-2 is required for both pericentriolar material recruitment and centriole duplication. | Q47068901 | ||
Centriolar SAS-5 is required for centrosome duplication in C. elegans | Q47069336 | ||
Centrosome maturation and duplication in C. elegans require the coiled-coil protein SPD-2. | Q47069578 | ||
Dominant-negative mutant dynein allows spontaneous centrosome assembly, uncouples chromosome and centrosome cycles. | Q47072461 | ||
SAS-4 is a C. elegans centriolar protein that controls centrosome size | Q47172631 | ||
SAS-4 is essential for centrosome duplication in C elegans and is recruited to daughter centrioles once per cell cycle | Q48255695 | ||
Kinetics and regulation of de novo centriole assembly. Implications for the mechanism of centriole duplication. | Q52137805 | ||
P433 | issue | 10 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Sak kinase Dmel_CG7186 | Q29811945 |
Spindle assembly abnormal 4 Dmel_CG10061 | Q29814452 | ||
Spindle assembly abnormal 6 Dmel_CG15524 | Q29816870 | ||
Fizzy-related Dmel_CG3000 | Q29817297 | ||
overexpression | Q61643320 | ||
P1104 | number of pages | 10 | |
P304 | page(s) | 834-843 | |
P577 | publication date | 2007-05-03 | |
P1433 | published in | Current Biology | Q1144851 |
P1476 | title | Overexpressing centriole-replication proteins in vivo induces centriole overduplication and de novo formation | |
P478 | volume | 17 |
Q47557430 | A "molecular guillotine" reveals an interphase function of Kinesin-5. |
Q92255391 | A Cancer-Associated Missense Mutation in PP2A-Aα Increases Centrosome Clustering during Mitosis |
Q33370199 | A genome-wide RNAi screen to dissect centriole duplication and centrosome maturation in Drosophila. |
Q52676506 | A homeostatic clock sets daughter centriole size in flies. |
Q34247080 | A molecular mechanism of mitotic centrosome assembly in Drosophila |
Q30482514 | A multicomponent assembly pathway contributes to the formation of acentrosomal microtubule arrays in interphase Drosophila cells |
Q38699702 | A non-canonical function of Plk4 in centriolar satellite integrity and ciliogenesis through PCM1 phosphorylation |
Q30540594 | A non-canonical mode of microtubule organization operates throughout pre-implantation development in mouse |
Q43138655 | A proximal centriole-like structure is present in Drosophila spermatids and can serve as a model to study centriole duplication |
Q24650428 | Ab ovo or de novo? Mechanisms of centriole duplication |
Q37131472 | Abnormal centrosomal structure and duplication in Cep135-deficient vertebrate cells |
Q52801590 | Adaptive optics in spinning disk microscopy: improved contrast and brightness by a simple and fast method. |
Q99611760 | Alstrom syndrome gene is a stem cell-specific regulator of centriole duplication in the Drosophila testis |
Q52678420 | An ordered pattern of Ana2 phosphorylation by Plk4 is required for centriole assembly. |
Q37425611 | Ana3 is a conserved protein required for the structural integrity of centrioles and basal bodies |
Q34329576 | Ancestral centriole and flagella proteins identified by analysis of Naegleria differentiation |
Q64976481 | Asterless is a Polo-like kinase 4 substrate that both activates and inhibits kinase activity depending on its phosphorylation state. |
Q24300230 | Asterless is a scaffold for the onset of centriole assembly |
Q30760961 | Asterless is required for centriole length control and sperm development |
Q35128950 | Autoinhibition and relief mechanism for Polo-like kinase 4. |
Q92763225 | Breaking Bad: Uncoupling of Modularity in Centriole Biogenesis and the Generation of Excess Centrioles in Cancer |
Q24319675 | Bug22 influences cilium morphology and the post-translational modification of ciliary microtubules |
Q34205722 | Building the Centriole |
Q30559130 | CP110 exhibits novel regulatory activities during centriole assembly in Drosophila |
Q34985452 | CPAP is a cell-cycle regulated protein that controls centriole length |
Q34474551 | Cell biology. Reversible centriole depletion with an inhibitor of Polo-like kinase 4. |
Q36959273 | Centriole biogenesis: a tale of two pathways |
Q34582145 | Centriole duplication: A lesson in self-control |
Q34149059 | Centriole duplication: analogue control in a digital age |
Q37080414 | Centriole inheritance |
Q42451265 | Centrioles to basal bodies in the spermiogenesis of Mastotermes darwiniensis (Insecta, Isoptera). |
Q33903451 | Centrioles: active players or passengers during mitosis? |
Q37077857 | Centrioles: some self-assembly required. |
Q58697392 | Centrosomal and Non-Centrosomal Microtubule-Organizing Centers (MTOCs) in |
Q37123357 | Centrosome amplification can initiate tumorigenesis in flies. |
Q41932064 | Centrosome amplification causes microcephaly |
Q34091715 | Centrosome biogenesis continues in the absence of microtubules during prolonged S-phase arrest |
Q21129300 | Centrosome dysfunction contributes to chromosome instability, chromoanagenesis, and genome reprograming in cancer |
Q36425489 | Centrosome loss or amplification does not dramatically perturb global gene expression in Drosophila |
Q24306268 | Cep152 acts as a scaffold for recruitment of Plk4 and CPAP to the centrosome |
Q34317054 | Cep152 interacts with Plk4 and is required for centriole duplication. |
Q36306041 | Chronic centrosome amplification without tumorigenesis |
Q24337720 | Ciliary and centrosomal defects associated with mutation and depletion of the Meckel syndrome genes MKS1 and MKS3 |
Q33320973 | Control of daughter centriole formation by the pericentriolar material |
Q30493185 | Control of mitotic and meiotic centriole duplication by the Plk4-related kinase ZYG-1 |
Q92763198 | Coordination of Embryogenesis by the Centrosome in Drosophila melanogaster |
Q51847585 | Cytokinesis remnants define first neuronal asymmetry in vivo. |
Q42871178 | DSas-6 and Ana2 coassemble into tubules to promote centriole duplication and engagement |
Q42468108 | Detachment of the basal body from the sperm tail is not required to organize functional centrosomes during Drosophila embryogenesis. |
Q24337416 | Deuterosome-mediated centriole biogenesis |
Q92621345 | Disruption of Dhcr7 and Insig1/2 in cholesterol metabolism causes defects in bone formation and homeostasis through primary cilium formation |
Q27311109 | Dissecting the function and assembly of acentriolar microtubule organizing centers in Drosophila cells in vivo |
Q37120397 | Drosophila Ana1 is required for centrosome assembly and centriole elongation |
Q33643718 | Drosophila Ana2 is a conserved centriole duplication factor |
Q92452377 | Drosophila Morgana is an Hsp90-interacting protein with a direct role in microtubule polymerisation |
Q36099474 | Drosophila Spd-2 recruits PCM to the sperm centriole, but is dispensable for centriole duplication. |
Q50671351 | Dynamic ordering of nuclei in syncytial embryos: a quantitative analysis of the role of cytoskeletal networks. |
Q59126926 | Emerging Picture of Deuterosome-Dependent Centriole Amplification in MCCs |
Q92568256 | Emerging roles of the centrosome in neuronal development |
Q36305968 | Epidermal development, growth control, and homeostasis in the face of centrosome amplification |
Q43102543 | Everything in moderation: Proteolytic regulation of centrosome duplication. |
Q39672963 | FM19G11: A new modulator of HIF that links mTOR activation with the DNA damage checkpoint pathways |
Q36045109 | Fluctuation Analysis of Centrosomes Reveals a Cortical Function of Kinesin-1. |
Q35980950 | From stem cell to embryo without centrioles |
Q46102906 | Function and dynamics of slam in furrow formation in early Drosophila embryo |
Q37295489 | Gamma-tubulin-containing abnormal centrioles are induced by insufficient Plk4 in human HCT116 colorectal cancer cells |
Q36144711 | Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition. |
Q42264164 | Growing microtubules push the oocyte nucleus to polarize the Drosophila dorsal-ventral axis |
Q24337030 | Human microcephaly protein CEP135 binds to hSAS-6 and CPAP, and is required for centriole assembly |
Q47732262 | Identification and cell cycle-dependent localization of nine novel, genuine centrosomal components in Dictyostelium discoideum |
Q34976788 | Identification of a polo-like kinase 4-dependent pathway for de novo centriole formation |
Q38280767 | Identification of novel regulatory factor X (RFX) target genes by comparative genomics in Drosophila species |
Q37379646 | In vitro oocyte culture-based manipulation of zebrafish maternal genes |
Q35797268 | Katanin p80 regulates human cortical development by limiting centriole and cilia number |
Q41928965 | Lack of centrioles and primary cilia in STIL(-/-) mouse embryos |
Q30480537 | Maintaining the proper connection between the centrioles and the pericentriolar matrix requires Drosophila centrosomin |
Q37780832 | Microscopy methods for the study of centriole biogenesis and function in Drosophila |
Q34408480 | Mps1 phosphorylation sites regulate the function of centrin 2 in centriole assembly |
Q49918080 | Novel STIL Compound Heterozygous Mutations Cause Severe Fetal Microcephaly and Centriolar Lengthening |
Q92709324 | NudC-like protein 2 restrains centriole amplification by stabilizing HERC2 |
Q33959903 | One to only two: a short history of the centrosome and its duplication |
Q24317665 | PLK2 phosphorylation is critical for CPAP function in procentriole formation during the centrosome cycle |
Q47675920 | Parthenogenesis in Insects: The Centriole Renaissance |
Q37092368 | Patronin/Shot Cortical Foci Assemble the Noncentrosomal Microtubule Array that Specifies the Drosophila Anterior-Posterior Axis. |
Q83232379 | Pericentrin-mediated SAS-6 recruitment promotes centriole assembly |
Q92303450 | Plk4 Regulates Centriole Asymmetry and Spindle Orientation in Neural Stem Cells |
Q42015542 | Plk4-dependent phosphorylation of STIL is required for centriole duplication. |
Q24336451 | Plk4-induced centriole biogenesis in human cells |
Q34344240 | Plk4/SAK/ZYG-1 in the regulation of centriole duplication |
Q30514031 | Polo-like kinase 4 controls centriole duplication but does not directly regulate cytokinesis |
Q50056269 | Polo-like kinase 4 inhibition produces polyploidy and apoptotic death of lung cancers |
Q33618895 | Polo-like kinase 4 kinase activity limits centrosome overduplication by autoregulating its own stability |
Q38222354 | Polo-like kinases: structural variations lead to multiple functions |
Q37080411 | Preformed cell structure and cell heredity |
Q36253730 | Protein Phosphatase 1 Down Regulates ZYG-1 Levels to Limit Centriole Duplication. |
Q24306609 | RBM14 prevents assembly of centriolar protein complexes and maintains mitotic spindle integrity |
Q24647101 | Regulated HsSAS-6 levels ensure formation of a single procentriole per centriole during the centrosome duplication cycle |
Q37871223 | Regulating the transition from centriole to basal body |
Q34166837 | Regulation of spindle pole body assembly and cytokinesis by the centrin-binding protein Sfi1 in fission yeast. |
Q57170231 | Revisiting Centrioles in Nematodes-Historic Findings and Current Topics |
Q30481426 | SAS-4 is recruited to a dynamic structure in newly forming centrioles that is stabilized by the gamma-tubulin-mediated addition of centriolar microtubules |
Q27674490 | SAS-6 coiled-coil structure and interaction with SAS-5 suggest a regulatory mechanism inC. eleganscentriole assembly |
Q53218420 | SAS-6 oligomerization: the key to the centriole? |
Q34749187 | Sas-4 proteins are required during basal body duplication in Paramecium |
Q28241376 | Sas-4 provides a scaffold for cytoplasmic complexes and tethers them in a centrosome |
Q64103389 | Self-organization of Plk4 regulates symmetry breaking in centriole duplication |
Q47867524 | Sequential activities of Dynein, Mud and Asp in centrosome-spindle coupling maintain centrosome number upon mitosis. |
Q38034629 | Show me your license, please: deregulation of centriole duplication mechanisms that promote amplification |
Q34328607 | SmSak, the second Polo-like kinase of the helminth parasite Schistosoma mansoni: conserved and unexpected roles in meiosis |
Q37340912 | Spindle assembly defects leading to the formation of a monopolar mitotic apparatus |
Q35953807 | Spindle pole body components are reorganized during fission yeast meiosis |
Q36242776 | The C. elegans F-box proteins LIN-23 and SEL-10 antagonize centrosome duplication by regulating ZYG-1 levels |
Q33642797 | The Centrioles, Centrosomes, Basal Bodies, and Cilia of Drosophila melanogaster. |
Q36648746 | The E2F-DP1 Transcription Factor Complex Regulates Centriole Duplication in Caenorhabditis elegans. |
Q24301726 | The Golgi protein GM130 regulates centrosome morphology and function |
Q38661406 | The Janus soul of centrosomes: a paradoxical role in disease? |
Q35406563 | The Protein Phosphatase 2A regulatory subunit Twins stabilizes Plk4 to induce centriole amplification |
Q37124885 | The SCF Slimb ubiquitin ligase regulates Plk4/Sak levels to block centriole reduplication. |
Q27305012 | The Seckel syndrome and centrosomal protein Ninein localizes asymmetrically to stem cell centrosomes but is not required for normal development, behavior, or DNA damage response in Drosophila |
Q27673542 | The Structure of the Plk4 Cryptic Polo Box Reveals Two Tandem Polo Boxes Required for Centriole Duplication |
Q36496562 | The autoregulated instability of Polo-like kinase 4 limits centrosome duplication to once per cell cycle |
Q33959920 | The centriole duplication cycle |
Q34221115 | The centrosome cycle: Centriole biogenesis, duplication and inherent asymmetries |
Q33691797 | The conserved protein SZY-20 opposes the Plk4-related kinase ZYG-1 to limit centrosome size |
Q35196084 | The conversion of centrioles to centrosomes: essential coupling of duplication with segregation |
Q33903444 | The elegans of spindle assembly |
Q42425294 | The homo-oligomerisation of both Sas-6 and Ana2 is required for efficient centriole assembly in flies |
Q24294326 | The human microcephaly protein STIL interacts with CPAP and is required for procentriole formation |
Q26798298 | The intimate genetics of Drosophila fertilization |
Q37627202 | The life cycle of centrioles |
Q34603390 | The two SAS-6 homologs in Tetrahymena thermophila have distinct functions in basal body assembly |
Q89837985 | The ubiquitin ligase FBXW7 targets the centriolar assembly protein HsSAS-6 for degradation and thereby regulates centriole duplication |
Q47105701 | Two-step phosphorylation of Ana2 by Plk4 is required for the sequential loading of Ana2 and Sas6 to initiate procentriole formation. |
Q52715449 | Uncoordinated centrosome cycle underlies the instability of non-diploid somatic cells in mammals. |
Q34772681 | Vertebrate maternal-effect genes: Insights into fertilization, early cleavage divisions, and germ cell determinant localization from studies in the zebrafish |
Q27310018 | p53 protects against genome instability following centriole duplication failure |
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