scholarly article | Q13442814 |
P2093 | author name string | Rebecca S Dise | |
Raymond C Harris | |||
Roy Zent | |||
D Brent Polk | |||
Yan Su | |||
Amar B Singh | |||
Mark R Frey | |||
Ambra Pozzi | |||
Maria R Ibanez | |||
Tristin D Abair | |||
Xiwu Chen | |||
P2860 | cites work | Alpha2beta1-integrin signaling by itself controls G1/S transition in a human adenocarcinoma cell line (Caco-2): implication of NADPH oxidase-dependent production of ROS. | Q40656808 |
Murine embryonic fibroblasts lacking TC-PTP display delayed G1 phase through defective NF-kappaB activation | Q40786997 | ||
Biochemical and biological characterization of a human Rac2 GTPase mutant associated with phagocytic immunodeficiency | Q40816848 | ||
Class- and splice variant-specific association of CD98 with integrin beta cytoplasmic domains | Q40900502 | ||
The biochemical basis of the NADPH oxidase of phagocytes. | Q40904508 | ||
Absence of integrin alpha1beta1 in the mouse causes loss of feedback regulation of collagen synthesis in normal and wounded dermis. | Q40981659 | ||
The alpha 1-alpha 6 subunits of integrins are characteristically expressed in distinct segments of developing and adult human nephron | Q42160122 | ||
Reactive oxygen species mediate high glucose-induced plasminogen activator inhibitor-1 up-regulation in mesangial cells and in diabetic kidney | Q42477089 | ||
Distribution and quantification of alpha 1-integrin subunit in rat organs | Q42486501 | ||
UV activates growth factor receptors via reactive oxygen intermediates | Q42772075 | ||
The Dbl-related protein, Lfc, localizes to microtubules and mediates the activation of Rac signaling pathways in cells | Q42820819 | ||
Rac, a small guanosine triphosphate-binding protein, and p21-activated kinase are activated during platelet spreading on collagen-coated surfaces: roles of integrin alpha(2)beta(1). | Q43819642 | ||
EGF receptor mediates adhesion-dependent activation of the Rac GTPase: a role for phosphatidylinositol 3-kinase and Vav2. | Q44573128 | ||
Early molecular events in the assembly of matrix adhesions at the leading edge of migrating cells. | Q44630472 | ||
Prevention of renal vascular and glomerular fibrosis by epidermal growth factor receptor inhibition | Q44807372 | ||
Mesangial cell NADPH oxidase upregulation in high glucose is protein kinase C dependent and required for collagen IV expression | Q46677686 | ||
Aldosterone stimulates reactive oxygen species production through activation of NADPH oxidase in rat mesangial cells | Q46681426 | ||
In high glucose protein kinase C-zeta activation is required for mesangial cell generation of reactive oxygen species | Q46826513 | ||
Targeted expression of activated Rac3 in mammary epithelium leads to defective postlactational involution and benign mammary gland lesions | Q47397860 | ||
Deletion of integrin alpha 1 by homologous recombination permits normal murine development but gives rise to a specific deficit in cell adhesion. | Q52201902 | ||
Rac1 GTPase regulates cell genomic stability and senescence. | Q53594389 | ||
Glomerular injury is exacerbated in diabetic integrin alpha1-null mice. | Q53617932 | ||
Platelet-derived growth factor and reactive oxygen species (ROS) regulate Ras protein levels in primary human fibroblasts via ERK1/2. Amplification of ROS and Ras in systemic sclerosis fibroblasts. | Q54650316 | ||
The expression of NADPH oxidase components in human glomerular mesangial cells: detection of protein and mRNA for p47phox, p67phox, and p22phox | Q72125888 | ||
Arachidonic acid-dependent activation of a p22(phox)-based NAD(P)H oxidase mediates angiotensin II-induced mesangial cell protein synthesis and fibronectin expression via Akt/PKB | Q80302357 | ||
ARF6 requirement for Rac ruffling suggests a role for membrane trafficking in cortical actin rearrangements | Q21632356 | ||
Identification of renox, an NAD(P)H oxidase in kidney | Q22254385 | ||
Role of Rac1 and oxygen radicals in collagenase-1 expression induced by cell shape change | Q24313072 | ||
Negative regulation of EGFR signalling through integrin-alpha1beta1-mediated activation of protein tyrosine phosphatase TCPTP | Q24321559 | ||
Mechanism of epidermal growth factor regulation of Vav2, a guanine nucleotide exchange factor for Rac | Q28216158 | ||
Generation and characterization of Rac3 knockout mice. | Q28511522 | ||
Rac2 is an essential regulator of neutrophil nicotinamide adenine dinucleotide phosphate oxidase activation in response to specific signaling pathways | Q28609618 | ||
Rho GTPases control polarity, protrusion, and adhesion during cell movement | Q29614244 | ||
Beta8 integrin binds Rho GDP dissociation inhibitor-1 and activates Rac1 to inhibit mesangial cell myofibroblast differentiation | Q30439181 | ||
Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expression. | Q30453215 | ||
Coactivation of Rac1 and Cdc42 at lamellipodia and membrane ruffles induced by epidermal growth factor. | Q30539004 | ||
The molecular basis for adhesion-mediated suppression of reactive oxygen species generation by human neutrophils | Q33630157 | ||
A novel superoxide-producing NAD(P)H oxidase in kidney | Q33921569 | ||
Integrins regulate Rac targeting by internalization of membrane domains | Q34295045 | ||
Assembly of the phagocyte NADPH oxidase: molecular interaction of oxidase proteins | Q34411802 | ||
H-Ras, R-Ras, and TC21 differentially regulate ureteric bud cell branching morphogenesis | Q34483633 | ||
Current molecular models for NADPH oxidase regulation by Rac GTPase | Q34915029 | ||
Elevated matrix metalloprotease and angiostatin levels in integrin alpha 1 knockout mice cause reduced tumor vascularization | Q35051209 | ||
Lack of integrin alpha1beta1 leads to severe glomerulosclerosis after glomerular injury. | Q35103022 | ||
Vascular NAD(P)H oxidases: specific features, expression, and regulation | Q35175526 | ||
A possible target of antioxidative therapy for diabetic vascular complications-vascular NAD(P)H oxidase | Q35181276 | ||
ROS generation by nonphagocytic NADPH oxidase: potential relevance in diabetic nephropathy | Q35182347 | ||
Effect of endogenous and exogenous EGF on the growth of EGF receptor-hyperproducing human squamous cell carcinoma implanted in nude mice | Q36081678 | ||
PTPs versus PTKs: the redox side of the coin | Q36199863 | ||
Integrin alpha1beta1 mediates a unique collagen-dependent proliferation pathway in vivo | Q36256242 | ||
A Rac switch regulates random versus directionally persistent cell migration | Q36320639 | ||
Integrins engage mitochondrial function for signal transduction by a mechanism dependent on Rho GTPases | Q36323820 | ||
Regulation of NADPH oxidases: the role of Rac proteins | Q36412266 | ||
Differential distribution and modulation of expression of alpha 1/beta 1 integrin on human endothelial cells | Q36532803 | ||
Regulation of the phagocyte NADPH oxidase by Rac GTPase | Q36598790 | ||
Nox4 mediates angiotensin II-induced activation of Akt/protein kinase B in mesangial cells | Q38352918 | ||
Adhesion to the extracellular matrix regulates the coupling of the small GTPase Rac to its effector PAK. | Q40387432 | ||
An activating mutant of Rac1 that fails to interact with Rho GDP-dissociation inhibitor stimulates membrane ruffling in mammalian cells | Q40615070 | ||
Rac1 deletion in mouse neutrophils has selective effects on neutrophil functions. | Q40646102 | ||
P433 | issue | 9 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | reactive oxygen species | Q424361 |
P304 | page(s) | 3313-3326 | |
P577 | publication date | 2007-03-05 | |
P1433 | published in | Molecular and Cellular Biology | Q3319478 |
P1476 | title | Integrin alpha1beta1 controls reactive oxygen species synthesis by negatively regulating epidermal growth factor receptor-mediated Rac activation | |
P478 | volume | 27 |
Q39752294 | Angiopoietin-1 reduces H(2)O(2)-induced increases in reactive oxygen species and oxidative damage to skin cells |
Q37019135 | Cell Receptor-Basement Membrane Interactions in Health and Disease: A Kidney-Centric View |
Q92132703 | Cell adhesion to collagen promotes leukemia resistance to doxorubicin by reducing DNA damage through the inhibition of Rac1 activation |
Q34582354 | Combined ChIP-Seq and transcriptome analysis identifies AP-1/JunD as a primary regulator of oxidative stress and IL-1β synthesis in macrophages |
Q35996764 | Contribution of Dual Oxidase 2 (DUOX2) to Hyper-Radiosensitivity in Human Gastric Cancer Cells |
Q38879377 | Contribution of collagen adhesion receptors to tissue fibrosis |
Q37151470 | Contribution of guanine nucleotide exchange factor Vav2 to hyperhomocysteinemic glomerulosclerosis in rats |
Q39326589 | Critical roles of the cAMP-responsive element-binding protein-mediated pathway in disorganized epithelial phenotypes caused by mitochondrial dysfunction |
Q41766522 | Cross-talk between integrins alpha1beta1 and alpha2beta1 in renal epithelial cells |
Q38932030 | Cyclic stretch-induced TGF-β1 and fibronectin expression is mediated by β1-integrin through c-Src- and STAT3-dependent pathways in renal epithelial cells |
Q34526996 | Diet-induced muscle insulin resistance is associated with extracellular matrix remodeling and interaction with integrin alpha2beta1 in mice |
Q26766089 | Dipeptidyl peptidase-4 and kidney fibrosis in diabetes |
Q36427883 | Distinct effects of β1 integrin on cell proliferation and cellular signaling in MDA-MB-231 breast cancer cells |
Q38901466 | EGFR inhibition protects cardiac damage and remodeling through attenuating oxidative stress in STZ-induced diabetic mouse model |
Q34081401 | Effects of high glucose on integrin activity and fibronectin matrix assembly by mesangial cells |
Q36318730 | Enhancing integrin α1 inserted (I) domain affinity to ligand potentiates integrin α1β1-mediated down-regulation of collagen synthesis |
Q33646704 | Epidermal growth factor receptor inhibition slows progression of diabetic nephropathy in association with a decrease in endoplasmic reticulum stress and an increase in autophagy |
Q34985774 | Epithelial β1 integrin is required for lung branching morphogenesis and alveolarization |
Q90688942 | Increased flux through the mevalonate pathway mediates fibrotic repair without injury |
Q37736555 | Inhibition of epidermal growth factor receptor attenuates atherosclerosis via decreasing inflammation and oxidative stress |
Q35982329 | Inhibition of integrin α2β1 ameliorates glomerular injury |
Q41998434 | Inhibition of integrin-mediated crosstalk with epidermal growth factor receptor/Erk or Src signaling pathways in autophagic prostate epithelial cells induces caspase-independent death |
Q40759373 | Integrin alpha1beta1 regulates epidermal growth factor receptor activation by controlling peroxisome proliferator-activated receptor gamma-dependent caveolin-1 expression |
Q34401055 | Integrin {alpha}1{beta}1 promotes caveolin-1 dephosphorylation by activating T cell protein-tyrosine phosphatase |
Q35173020 | Integrin α1-null mice exhibit improved fatty liver when fed a high fat diet despite severe hepatic insulin resistance |
Q35937053 | Integrin α1/Akita double-knockout mice on a Balb/c background develop advanced features of human diabetic nephropathy |
Q33638043 | Integrin α1β1 differentially regulates cytokine-mediated responses in chondrocytes |
Q38726100 | Integrin-FAK signaling rapidly and potently promotes mitochondrial function through STAT3 |
Q33944185 | Integrin-mediated type II TGF-β receptor tyrosine dephosphorylation controls SMAD-dependent profibrotic signaling |
Q27010694 | Integrins in kidney disease |
Q41884394 | Loss of integrin alpha1beta1 ameliorates Kras-induced lung cancer |
Q37225320 | Matrix metalloproteinases and matrix receptors in progression and reversal of kidney disease: therapeutic perspectives |
Q27025492 | Matrix metalloproteinases, atherosclerosis, proteinuria and kidney disease: Linkage-based approaches |
Q37421274 | Modulation of reactive oxygen species by Rac1 or catalase prevents asbestos-induced pulmonary fibrosis |
Q30483218 | Neural stem cell transplantation can ameliorate the phenotype of a mouse model of spinal muscular atrophy |
Q38465785 | Quantitative proteomic profiling of renal tissue in human chronic rejection biopsy samples after renal transplantation. |
Q37430721 | Rac1 promotes TGF-beta-stimulated mesangial cell type I collagen expression through a PI3K/Akt-dependent mechanism. |
Q33397843 | Rac1 regulates pancreatic islet morphogenesis |
Q34042822 | Rac1-mediated mitochondrial H2O2 generation regulates MMP-9 gene expression in macrophages via inhibition of SP-1 and AP-1 |
Q36970633 | Redox control of renal function and hypertension. |
Q36256857 | Role of integrin subunits in mesenchymal stem cell differentiation and osteoblast maturation on graphitic carbon-coated microstructured surfaces. |
Q36654870 | Serum Metabolite Profiles Are Altered by Erlotinib Treatment and the Integrin α1-Null Genotype but Not by Post-Traumatic Osteoarthritis |
Q90393787 | Stimulation of Fibronectin Matrix Assembly by Lysine Acetylation |
Q51636281 | Stimulatory effects of advanced glycation endproducts (AGEs) on fibronectin matrix assembly. |
Q37096498 | TGFβ receptor I transactivation mediates stretch-induced Pak1 activation and CTGF upregulation in mesangial cells |
Q26768149 | The integrin-collagen connection--a glue for tissue repair? |
Q37993661 | The role of cell-extracellular matrix interactions in glomerular injury |
Q38055432 | The role of promoter hypermethylation in fibroblast activation and fibrogenesis |
Q35151696 | Therapeutic IMC-C225 antibody inhibits breast cancer cell invasiveness via Vav2-dependent activation of RhoA GTPase |
Q48337958 | Type IV collagen induces expression of thrombospondin-1 that is mediated by integrin alpha1beta1 in astrocytes. |
Q39102273 | Understanding the role of structural integrity and differential expression of integrin profiling to identify potential therapeutic targets in breast cancer. |
Q35587361 | p47(phox) contributes to albuminuria and kidney fibrosis in mice |
Q92228770 | β1 Integrin regulates adult lung alveolar epithelial cell inflammation |
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