| scholarly article | Q13442814 |
| P2093 | author name string | Dehua Pei | |
| Punit Upadhyaya | |||
| Ziqing Qian | |||
| Thi B Trinh | |||
| P2860 | cites work | Identifying genotype-dependent efficacy of single and combined PI3K- and MAPK-pathway inhibition in cancer | Q37376100 |
| Ras signaling and therapies | Q37548931 | ||
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| Sulindac-derived Ras pathway inhibitors target the Ras-Raf interaction and downstream effectors in the Ras pathway | Q40597101 | ||
| Synergy between PI3K/Akt and Raf/MEK/ERK pathways in IGF-1R mediated cell cycle progression and prevention of apoptosis in hematopoietic cells | Q40598838 | ||
| Therapeutic targeting of oncogenic K-Ras by a covalent catalytic site inhibitor | Q41915120 | ||
| Efficient Delivery of Cyclic Peptides into Mammalian Cells with Short Sequence Motifs | Q42116534 | ||
| Climbing RAS, the Everest of Oncogenes | Q57280773 | ||
| Kinetics of interaction of nucleotides with nucleotide-free H-ras p21 | Q59663104 | ||
| Traceless capping agent for peptide sequencing by partial edman degradation and mass spectrometry | Q80104181 | ||
| Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signalling | Q24293500 | ||
| Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays | Q25939005 | ||
| Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase gamma | Q27629132 | ||
| In silico discovery of small-molecule Ras inhibitors that display antitumor activity by blocking the Ras-effector interaction | Q27677868 | ||
| Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity | Q27678097 | ||
| Discovery of Small Molecules that Bind to K‐Ras and Inhibit Sos‐Mediated Activation | Q27678948 | ||
| K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions | Q27680654 | ||
| A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes | Q28219495 | ||
| Hydrocarbon-stapled peptides: principles, practice, and progress | Q28542025 | ||
| Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha | Q28616168 | ||
| Reaching for high-hanging fruit in drug discovery at protein-protein interfaces | Q29547258 | ||
| A comprehensive survey of Ras mutations in cancer | Q30416821 | ||
| A novel peptide-based encoding system for "one-bead one-compound" peptidomimetic and small molecule combinatorial libraries | Q31087756 | ||
| High-throughput sequence determination of cyclic peptide library members by partial Edman degradation/mass spectrometry | Q33258459 | ||
| On-bead screening of combinatorial libraries: reduction of nonspecific binding by decreasing surface ligand density | Q33435541 | ||
| Early endosomal escape of a cyclic cell-penetrating peptide allows effective cytosolic cargo delivery | Q33824686 | ||
| Peptidotriazoles on solid phase: [1,2,3]-triazoles by regiospecific copper(i)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides | Q33958790 | ||
| An efficient, inexpensive, and shelf-stable diazotransfer reagent: imidazole-1-sulfonyl azide hydrochloride | Q34005894 | ||
| Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors | Q34121272 | ||
| Direct Ras Inhibitors Identified from a Structurally Rigidified Bicyclic Peptide Library | Q34271187 | ||
| Inhibition of Ras–effector interactions by cyclic peptides | Q34668051 | ||
| The challenge of drugging undruggable targets in cancer: lessons learned from targeting BCL-2 family members | Q34727955 | ||
| Screening Bicyclic Peptide Libraries for Protein–Protein Interaction Inhibitors: Discovery of a Tumor Necrosis Factor-α Antagonist | Q34832185 | ||
| Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices | Q35089991 | ||
| Small-molecule modulation of Ras signaling | Q35188280 | ||
| Inhibition of Ras signaling by blocking Ras-effector interactions with cyclic peptides | Q35624144 | ||
| An orthosteric inhibitor of the Ras-Sos interaction | Q35854216 | ||
| Monitoring the cytosolic entry of cell-penetrating peptides using a pH-sensitive fluorophore | Q35997331 | ||
| Ras trafficking, localization and compartmentalized signalling | Q36043314 | ||
| A Selective, Cell-Permeable Nonphosphorylated Bicyclic Peptidyl Inhibitor against Peptidyl-Prolyl Isomerase Pin1. | Q36124025 | ||
| Andrographolide derivatives inhibit guanine nucleotide exchange and abrogate oncogenic Ras function | Q36950248 | ||
| P433 | issue | 1 | |
| P304 | page(s) | 75-85 | |
| P577 | publication date | 2015-12-08 | |
| P1433 | published in | ACS combinatorial science | Q27723471 |
| P1476 | title | Discovery of a Direct Ras Inhibitor by Screening a Combinatorial Library of Cell-Permeable Bicyclic Peptides | |
| P478 | volume | 18 |
| Q64993130 | A Comprehensive Review on Current Advances in Peptide Drug Development and Design. |
| Q36281478 | An Integrated Microfluidic Processor for DNA-Encoded Combinatorial Library Functional Screening |
| Q55618585 | BRET-based RAS biosensors that show a novel small molecule is an inhibitor of RAS-effector protein-protein interactions. |
| Q36394825 | Bicyclic Peptides as Next-Generation Therapeutics. |
| Q90307720 | Bifunctional Small-Molecule Ligands of K-Ras Induce Its Association with Immunophilin Proteins |
| Q47586545 | Cell-Penetrating Peptides: Design Strategies beyond Primary Structure and Amphipathicity |
| Q58698975 | Cell-Permeable Bicyclic Peptidyl Inhibitors against NEMO-IκB Kinase Interaction Directly from a Combinatorial Library |
| Q47425774 | Cell-permeable bicyclic peptidyl inhibitors against T-cell protein tyrosine phosphatase from a combinatorial library |
| Q36369338 | Combinatorial chemistry in drug discovery |
| Q89838002 | Conformation-specific inhibitors of activated Ras GTPases reveal limited Ras dependency of patient-derived cancer organoids |
| Q90691323 | Development of a Cell-Permeable Cyclic Peptidyl Inhibitor against the Keap1-Nrf2 Interaction |
| Q64233821 | Discovery of High-Affinity Noncovalent Allosteric KRAS Inhibitors That Disrupt Effector Binding |
| Q38891257 | Drugging Ras GTPase: a comprehensive mechanistic and signaling structural view |
| Q47443285 | Efforts to Develop KRAS Inhibitors |
| Q40402014 | Enhancing the Cell Permeability and Metabolic Stability of Peptidyl Drugs by Reversible Bicyclization. |
| Q92258798 | Exploiting RAS Nucleotide Cycling as a Strategy for Drugging RAS-Driven Cancers |
| Q50995283 | Generation of a cell-permeable cycloheptapeptidyl inhibitor against the peptidyl-prolyl isomerase Pin1. |
| Q36266199 | Highly Constrained Bicyclic Scaffolds for the Discovery of Protease-Stable Peptides via mRNA Display |
| Q47155582 | Identification of a New Potent Inhibitor Targeting KRAS in Non-small Cell Lung Cancer Cells |
| Q36309720 | Macrocycles as protein-protein interaction inhibitors |
| Q89515224 | Miniproteins as a Powerful Modality in Drug Development |
| Q38289100 | New Modalities for Challenging Targets in Drug Discovery |
| Q36242161 | Nonclassical Size Dependence of Permeation Defines Bounds for Passive Adsorption of Large Drug Molecules. |
| Q90748676 | Peptide Combination Generator: a Tool for Generating Peptide Combinations |
| Q37057254 | Polysaccharide Nanoparticles for Efficient siRNA Targeting in Cancer Cells by Supramolecular pKa Shift |
| Q90859674 | Precision medicine by designer interference peptides: applications in oncology and molecular therapeutics |
| Q49803798 | Rapid, sensitive, and in-solution screening of peptide probes for targeted imaging of live cancer cells based on peptide recognition-induced emission |
| Q90614482 | Recent Trends in Cyclic Peptides as Therapeutic Agents and Biochemical Tools |
| Q42358786 | Stereochemistry Balances Cell Permeability and Solubility in the Naturally Derived Phepropeptin Cyclic Peptides |
| Q47989097 | Targeting Ras with Macromolecules |
| Q36339706 | Targeting intracellular protein-protein interactions with cell-permeable cyclic peptides |
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