Glucose-6-phosphate dehydrogenase, NADPH, and cell survival

scientific article published on 20 March 2012

Glucose-6-phosphate dehydrogenase, NADPH, and cell survival is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/IUB.1017
P932PMC publication ID3325335
P698PubMed publication ID22431005
P5875ResearchGate publication ID221723643

P2093author name stringRobert C Stanton
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Glucose-6-phosphate dehydrogenase: a "housekeeping" enzyme subject to tissue-specific regulation by hormones, nutrients, and oxidant stressQ28250165
Importance of glucose-6-phosphate dehydrogenase activity for cell growthQ28268412
HGF suppresses high glucose-mediated oxidative stress in mesangial cells by activation of PKG and inhibition of PKAQ28564992
Synergistic activation of glucose-6-phosphate dehydrogenase and NAD(P)H oxidase by Src kinase elevates superoxide in type 2 diabetic, Zucker fa/fa, rat liverQ28573824
Glucose-6-phosphate dehydrogenase activity and NADPH/NADP+ ratio in liver and pancreas are dependent on the severity of hyperglycemia in ratQ28583459
A glucose-6-phosphate dehydrogenase (G6PD) splice site consensus sequence mutation associated with G6PD enzyme deficiencyQ28586870
Targeted disruption of the housekeeping gene encoding glucose 6-phosphate dehydrogenase (G6PD): G6PD is dispensable for pentose synthesis but essential for defense against oxidative stressQ28589916
Importance of glucose-6-phosphate dehydrogenase activity in cell deathQ28646889
Activation of a metabolic gene regulatory network downstream of mTOR complex 1Q29615179
Glucose-6-phosphate dehydrogenase overexpression decreases endothelial cell oxidant stress and increases bioavailable nitric oxideQ30890753
Nephro-protective effects of a ginger extract on cytosolic and mitochondrial enzymes against streptozotocin (STZ)-induced diabetic complications in ratsQ84594752
Glucose-6-phosphate dehydrogenase modulates vascular endothelial growth factor-mediated angiogenesisQ30939997
G6PD deficiency: its role in the high prevalence of hypertension and diabetes mellitus.Q33336741
Glucose-6-phosphate dehydrogenase-deficient mice have increased renal oxidative stress and increased albuminuriaQ33613186
High glucose inhibits glucose-6-phosphate dehydrogenase, leading to increased oxidative stress and beta-cell apoptosisQ33890987
Maternally transmitted severe glucose 6-phosphate dehydrogenase deficiency is an embryonic lethalQ34090494
Human alpha B-crystallin mutation causes oxido-reductive stress and protein aggregation cardiomyopathy in miceQ34231667
Animal models of diabetes mellitus.Q34405860
Sterol regulatory element-binding proteins: transcriptional activators of lipid synthesisQ35003607
Reactive oxygen species and cell signaling: respiratory burst in macrophage signalingQ35019701
p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenaseQ35032943
G6PD--an old bottle with new wine.Q36329158
Molecular mechanism of phase I and phase II drug-metabolizing enzymes: implications for detoxificationQ36812605
Aldosterone impairs vascular reactivity by decreasing glucose-6-phosphate dehydrogenase activityQ36829138
Superoxide production by NAD(P)H oxidase and mitochondria is increased in genetically obese and hyperglycemic rat heart and aorta before the development of cardiac dysfunction. The role of glucose-6-phosphate dehydrogenase-derived NADPH.Q37264479
Glucose-6-phosphate dehydrogenase laboratory assay: How, when, and why?Q37305609
The global prevalence of glucose-6-phosphate dehydrogenase deficiency: a systematic review and meta-analysisQ37398327
Enzyme stimulation upon fertilization is revealed in electrically permeabilized sea urchin eggsQ37485831
Regulation of pentose phosphate pathway dehydrogenases by NADP+/NADPH ratiosQ39080278
G6PD up-regulation promotes pancreatic beta-cell dysfunctionQ39605614
Physiological functions of the pentose phosphate pathwayQ39751184
NADPH oxidases: molecular understanding finally reaching the clinical level?Q39988593
Protective role of 1 alpha, 25-dihydroxyvitamin D3 against oxidative stress in nonmalignant human prostate epithelial cellsQ40001271
Signal transduction proteins that associate with the platelet-derived growth factor (PDGF) receptor mediate the PDGF-induced release of glucose-6-phosphate dehydrogenase from permeabilized cellsQ41467294
Rapid release of bound glucose-6-phosphate dehydrogenase by growth factors. Correlation with increased enzymatic activityQ41675294
Effect of adrenaline and phorbol myristate acetate or bacterial lipopolysaccharide on stimulation of pathways of macrophage glucose, glutamine and O2 metabolism. Evidence for cyclic AMP-dependent protein kinase mediated inhibition of glucose-6-phospQ42146944
Benfotiamine improves functional recovery of the infarcted heart via activation of pro-survival G6PD/Akt signaling pathway and modulation of neurohormonal responseQ42158257
Glucose 6-phosphate dehydrogenase is regulated through c-Src-mediated tyrosine phosphorylation in endothelial cellsQ42452009
Arachidonic acid inhibits the insulin induction of glucose-6-phosphate dehydrogenase via p38 MAP kinaseQ42484978
Human glucose-6-phosphate dehydrogenase (G6PD) gene transforms NIH 3T3 cells and induces tumors in nude miceQ42804637
Increased prevalence of proliferative retinopathy in patients with type 1 diabetes who are deficient in glucose-6-phosphate dehydrogenaseQ43594309
High glucose impairs superoxide production from isolated blood neutrophilsQ44293200
Renal cell carcinoma and oxidative stress: The lack of peroxisomes.Q45980844
Diabetes causes inhibition of glucose-6-phosphate dehydrogenase via activation of PKA, which contributes to oxidative stress in rat kidney cortexQ46547434
Elevated activity of the oxidative and non-oxidative pentose phosphate pathway in (pre)neoplastic lesions in rat liver.Q46636561
Insulin regulation of glucose-6-phosphate dehydrogenase gene expression is rapamycin-sensitive and requires phosphatidylinositol 3-kinaseQ48010610
Glucose-6-phosphate dehydrogenase deficiency and diabetes mellitusQ67833108
The Control of Oxidant Stress at FertilizationQ67915639
Association of glucose-6-phosphate dehydrogenase deficiency with diabetes mellitusQ70027658
High glucose inhibits glucose-6-phosphate dehydrogenase via cAMP in aortic endothelial cellsQ73010828
Enhanced oxidative stress and accelerated cellular senescence in glucose-6-phosphate dehydrogenase (G6PD)-deficient human fibroblastsQ74297486
Inhibition of the oxidative and nonoxidative pentose phosphate pathways by somatostatin: a possible mechanism of antitumor actionQ77115675
Nrf2 is involved in the effect of tanshinone IIA on intracellular redox status in human aortic smooth muscle cellsQ79781005
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)362-369
P577publication date2012-03-20
P1433published inIUBMB LifeQ15764029
P1476titleGlucose-6-phosphate dehydrogenase, NADPH, and cell survival
P478volume64

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