The incidence and clinical significance of nucleophosmin mutations in childhood AML.

scientific article published on 17 April 2007

The incidence and clinical significance of nucleophosmin mutations in childhood AML. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1182/BLOOD-2007-02-076604
P932PMC publication ID1924773
P698PubMed publication ID17440048
P5875ResearchGate publication ID6388684

P50authorRachel RauQ55283665
P2093author name stringPatrick Brown
Soheil Meshinchi
Donald Small
Todd A Alonzo
Gary Dahl
Myron Chang
Norman Lacayo
Robert J Arceci
Emily McIntyre
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Mutant nucleophosmin (NPM1) predicts favorable prognosis in younger adults with acute myeloid leukemia and normal cytogenetics: interaction with other gene mutationsQ27824843
Nucleophosmin gene mutations are predictors of favorable prognosis in acute myelogenous leukemia with a normal karyotypeQ27824844
Prevalence and prognostic impact of NPM1 mutations in 1485 adult patients with acute myeloid leukemia (AML).Q27824861
Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphomaQ28250347
The importance of diagnostic cytogenetics on outcome in AML: analysis of 1,612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children's Leukaemia Working PartiesQ28283156
ARF impedes NPM/B23 shuttling in an Mdm2-sensitive tumor suppressor pathwayQ28506702
Tryptophans 286 and 288 in the C-terminal region of protein B23.1 are important for its nucleolar localizationQ28572689
Randomized use of cyclosporin A (CsA) to modulate P-glycoprotein in children with AML in remission: Pediatric Oncology Group Study 9421.Q30444746
Prevalence and prognostic significance of Flt3 internal tandem duplication in pediatric acute myeloid leukemiaQ31774863
The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: analysis of 854 patients from the UniteQ34517403
DNA repair during organogenesisQ34994569
Clinical implications of FLT3 mutations in pediatric AML.Q35848876
Environmental genotoxicants/carcinogens and childhood cancer: bridgeable gaps in scientific knowledgeQ36531134
Mutations in nucleophosmin (NPM1) in acute myeloid leukemia (AML): association with other gene abnormalities and previously established gene expression signatures and their favorable prognostic significanceQ38321981
Gene expression profiles at diagnosis in de novo childhood AML patients identify FLT3 mutations with good clinical outcomesQ38338957
Prognostic significance of activating FLT3 mutations in younger adults (16 to 60 years) with acute myeloid leukemia and normal cytogenetics: a study of the AML Study Group Ulm.Q44189526
Biallelic mutations in the CEBPA gene and low CEBPA expression levels as prognostic markers in intermediate-risk AML.Q44401465
Hazard Rate Models with CovariatesQ52776795
FLT3, RAS, and TP53 mutations in elderly patients with acute myeloid leukemia.Q54008419
Quantitative assessment of minimal residual disease in acute myeloid leukemia carrying nucleophosmin (NPM1) gene mutations.Q54613492
Detection of normal and chimeric nucleophosmin in human cellsQ61411738
Preribosomal ribonucleoprotein particles are a major component of a nucleolar matrix fractionQ70026444
Favorable prognostic significance of CEBPA mutations in patients with de novo acute myeloid leukemia: a study from the Acute Leukemia French Association (ALFA)Q78290356
Different types of NPM1 mutations in children and adults: evidence for an effect of patient age on the prevalence of the TCTG-tandem duplication in NPM1-exon 12Q79412055
Clinical implications of minimal residual disease monitoring by quantitative polymerase chain reaction in acute myeloid leukemia patients bearing nucleophosmin (NPM1) mutationsQ79954785
Aberrant subcellular expression of nucleophosmin and NPM-MLF1 fusion protein in acute myeloid leukaemia carrying t(3;5): a comparison with NPMc+ AMLQ81600809
Nucleophosmin mutations in childhood acute myelogenous leukemia with normal karyotypeQ81712971
Clinical characteristics and prognostic implications of NPM1 mutations in acute myeloid leukemiaQ81919725
Nucleophosmin mutations in de novo acute myeloid leukemia: the age-dependent incidences and the stability during disease evolutionQ82843896
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)979-985
P577publication date2007-04-17
P1433published inBloodQ885070
P1476titleThe incidence and clinical significance of nucleophosmin mutations in childhood AML.
P478volume110

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