Restoration of mechanical and energetic function in failing aortic-banded rat hearts by gene transfer of calcium cycling proteins

scientific article

Restoration of mechanical and energetic function in failing aortic-banded rat hearts by gene transfer of calcium cycling proteins is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.YJMCC.2007.01.003
P8608Fatcat IDrelease_lat5dy4juba2hgcfkl5jhwr57m
P932PMC publication ID1945057
P698PubMed publication ID17300800
P5875ResearchGate publication ID6504253

P2093author name stringRoger J Hajjar
Djamel Lebeche
Woo Jin Park
Yoshiaki Kawase
Susumu Sakata
Federica del Monte
Dongtak Jeong
Yoshiaki Takewa
Elie R Chemaly
Krisztina Zsebo
Li Fan Liang
Naoya Sakata
Richard Peluso
Tsuyoshi Tsuji
Yuri Sakata
P2860cites workRestoration of contractile function in isolated cardiomyocytes from failing human hearts by gene transfer of SERCA2aQ22010899
Molecular basis of cardiac performance. Plasticity of the myocardium generated through protein isoform switchesQ24621025
Calcium fluxes involved in control of cardiac myocyte contractionQ28144050
Cardiac excitation-contraction couplingQ28216347
Improvement in survival and cardiac metabolism after gene transfer of sarcoplasmic reticulum Ca(2+)-ATPase in a rat model of heart failureQ28354203
In vivo acceleration of heart relaxation performance by parvalbumin gene deliveryQ30501538
Prospects for gene therapy for heart failureQ33881236
Myofilament calcium regulation in human myocardiumQ34074806
Adenoviral gene transfer of SERCA2a improves left-ventricular function in aortic-banded rats in transition to heart failureQ34978011
Clinical use of inotropic therapy for heart failure: looking backward or forward? Part II: chronic inotropic therapyQ35186772
Abnormalities in intracellular calcium regulation and contractile function in myocardium from dogs with pacing-induced heart failureQ35599387
Modulation of ventricular function through gene transfer in vivoQ36067860
Secretion of a TNFR:Fc fusion protein following pulmonary administration of pseudotyped adeno-associated virus vectorsQ37596958
Abrogation of ventricular arrhythmias in a model of ischemia and reperfusion by targeting myocardial calcium cyclingQ37682472
Ventricular energeticsQ37911389
Myosin isoenzyme redistribution in chronic heart overloadQ39575052
Characterization of cardiac sarcoplasmic reticulum dysfunction during short-term, normothermic, global ischemiaQ41536389
Cardiac dysfunction in terms of left ventricular mechanical work and energetics in hypothyroid ratsQ44068487
In vivo gene transfer of parvalbumin improves diastolic function in aged rat heartsQ45882717
Mechanical and metabolic rescue in a type II diabetes model of cardiomyopathy by targeted gene transferQ46964433
Gene transfer of parvalbumin improves diastolic dysfunction in senescent myocytesQ47406744
Relationship between Na+-Ca2+-exchanger protein levels and diastolic function of failing human myocardiumQ48749719
Restoration of diastolic function in senescent rat hearts through adenoviral gene transfer of sarcoplasmic reticulum Ca(2+)-ATPase.Q51417559
Normal myocardial function and energetics in volume-overload hypertrophy in the cat.Q53711704
Mechanisms for the abnormal energetics of pressure-induced hypertrophy of cat myocardium.Q54402659
Myocardial oxygen consumption during experimental hypertrophy and congestive heart failureQ68506541
Decreased contractile efficiency and increased nonmechanical energy cost in hyperthyroid rabbit heart. Relation between O2 consumption and systolic pressure-volume area or force-time integralQ68737367
Abnormal intracellular calcium handling in myocardium from patients with end-stage heart failureQ69122833
Altered calcium handling in experimental pressure-overload hypertrophy in the ferretQ69979818
Decreased energy reserve in an animal model of dilated cardiomyopathy. Relationship to contractile performanceQ71056599
Alterations of Sarcoplasmic Reticulum Proteins in Failing Human Dilated CardiomyopathyQ71974451
Relation between myocardial function and expression of sarcoplasmic reticulum Ca(2+)-ATPase in failing and nonfailing human myocardiumQ72133115
Altered stoichiometry of FKBP12.6 versus ryanodine receptor as a cause of abnormal Ca(2+) leak through ryanodine receptor in heart failureQ73108723
Upregulation of Na(+)/Ca(2+) exchanger expression and function in an arrhythmogenic rabbit model of heart failureQ73204498
Pharmacological modulation of pressure-overload cardiac hypertrophy: changes in ventricular function, extracellular matrix, and gene expressionQ73804365
No dependency of a new index for oxygen cost of left ventricular contractility on heart rates in the blood-perfused excised rat heartQ74019123
Contribution of abnormal sarcoplasmic reticulum ATPase activity to systolic and diastolic dysfunction in human heart failureQ77502354
Na/Ca exchange in heart failure: contractile dysfunction and arrhythmogenesisQ78719599
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectaortaQ101004
P304page(s)852-861
P577publication date2007-01-10
P1433published inJournal of Molecular and Cellular CardiologyQ2061932
P1476titleRestoration of mechanical and energetic function in failing aortic-banded rat hearts by gene transfer of calcium cycling proteins
P478volume42

Reverse relations

cites work (P2860)
Q28297096AAV-mediated gene therapy for heart failure: enhancing contractility and calcium handling
Q34248473AAV6.βARKct cardiac gene therapy ameliorates cardiac function and normalizes the catecholaminergic axis in a clinically relevant large animal heart failure model
Q34132686Adeno-associated virus (AAV) serotype 9 provides global cardiac gene transfer superior to AAV1, AAV6, AAV7, and AAV8 in the mouse and rat.
Q37766138Advances in gene-based therapy for heart failure
Q37239340Alterations in ryanodine receptors and related proteins in heart failure
Q35116100Altered myocardial calcium cycling and energetics in heart failure--a rational approach for disease treatment
Q36837270Altered sarcoplasmic reticulum calcium cycling--targets for heart failure therapy
Q36313661Ameliorated stress related proteins are associated with improved cardiac function by sarcoplasmic reticulum calcium ATPase gene transfer in heart failure
Q51869172Benefit of SERCA2a gene transfer to vascular endothelial and smooth muscle cells: a new aspect in therapy of cardiovascular diseases.
Q34195822Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID): a phase 2 trial of intracoronary gene therapy of sarcoplasmic reticulum Ca2+-ATPase in patients with advanced heart failure
Q27026716Calcium mishandling in diastolic dysfunction: mechanisms and potential therapies
Q37364786Calcium upregulation by percutaneous administration of gene therapy in cardiac disease (CUPID Trial), a first-in-human phase 1/2 clinical trial.
Q38916981Calcium upregulation by percutaneous administration of gene therapy in patients with cardiac disease (CUPID 2): a randomised, multinational, double-blind, placebo-controlled, phase 2b trial
Q34409721Cardiac Gene Therapy
Q46952259Cardiac contractility modulation therapy in advanced systolic heart failure
Q37811189Cardiac gene therapy with SERCA2a: From bench to bedside
Q35174923Cardiac gene transfer of short hairpin RNA directed against phospholamban effectively knocks down gene expression but causes cellular toxicity in canines
Q27691424Cardiac-targeted delivery of regulatory RNA molecules and genes for the treatment of heart failure
Q45872017Cardio-specific long-term gene expression in a porcine model after selective pressure-regulated retroinfusion of adeno-associated viral (AAV) vectors
Q38788217Current Methods in Cardiac Gene Therapy: Overview
Q37299072Designing heart performance by gene transfer.
Q43544082Differential patterns of replacement and reactive fibrosis in pressure and volume overload are related to the propensity for ischaemia and involve resistin
Q89782554Dysregulation of Calcium Handling in Duchenne Muscular Dystrophy-Associated Dilated Cardiomyopathy: Mechanisms and Experimental Therapeutic Strategies
Q37685861Effect of bortezomib on the efficacy of AAV9.SERCA2a treatment to preserve cardiac function in a rat pressure-overload model of heart failure.
Q37950457Endogenous migration modulators as parent compounds for the development of novel cardiovascular and anti-inflammatory drugs
Q34092888Enhanced basal contractility but reduced excitation-contraction coupling efficiency and beta-adrenergic reserve of hearts with increased Cav1.2 activity
Q57030935Epigallocatechin-3 gallate prevents pressure overload-induced heart failure by up-regulating SERCA2a via histone acetylation modification in mice
Q38025012Gene and cytokine therapy for heart failure: molecular mechanisms in the improvement of cardiac function
Q34130135Gene delivery of sarcoplasmic reticulum calcium ATPase inhibits ventricular remodeling in ischemic mitral regurgitation
Q33804951Gene therapies for arrhythmias in heart failure
Q83556143Gene therapy for heart failure
Q38073152Gene therapy for heart failure: where do we stand?
Q36953151Gene therapy for the treatment of heart failure: promise postponed
Q30539495Gene transfer in skeletal and cardiac muscle using recombinant adeno-associated virus
Q51116860Impaired left ventricular mechanical and energetic function in mice after cardiomyocyte-specific excision of Serca2.
Q38830312Importance of SERCA2a on early isolated diastolic dysfunction induced by supravalvular aortic stenosis in rats
Q45886178Intramyocardial injection of SERCA2a-expressing lentivirus improves myocardial function in doxorubicin-induced heart failure
Q97569409Investigation of the safety and feasibility of AAV1/SERCA2a gene transfer in patients with chronic heart failure supported with a left ventricular assist device - the SERCA-LVAD TRIAL
Q43110528Long-term cardiac-targeted RNA interference for the treatment of heart failure restores cardiac function and reduces pathological hypertrophy
Q37162555Mechanical work and energetic analysis of eccentric cardiac remodeling in a volume overload heart failure in rats
Q37101211Mechanisms of disease: ion channel remodeling in the failing ventricle
Q36042518Mechanisms of ventricular arrhythmias: a dynamical systems-based perspective
Q26823061Model-specific selection of molecular targets for heart failure gene therapy
Q24337593Modulation of cardiac contractility by the phospholamban/SERCA2a regulatome
Q37643467Molecular cardiology in translation: gene, cell and chemical-based experimental therapeutics for the failing heart.
Q53073861Myocardial reverse remodeling after pressure unloading is associated with maintained cardiac mechanoenergetics in a rat model of left ventricular hypertrophy.
Q51370275Myocardial twitch duration and the dependence of oxygen consumption on pressure-volume area: experiments and modelling.
Q37068663Pathological hypertrophy amelioration by PRAS40-mediated inhibition of mTORC1
Q46022665Pim-1 regulates cardiomyocyte survival downstream of Akt.
Q36951008Plasticity of surface structures and β(2)-adrenergic receptor localization in failing ventricular cardiomyocytes during recovery from heart failure
Q30383732Post-translational Modifications in Heart Failure: Small Changes, Big Impact
Q36497159Potential of gene therapy as a treatment for heart failure
Q34627450Progesterone modulates SERCA2a expression and function in rabbit cardiomyocytes
Q39356341Promise of adeno-associated virus as a gene therapy vector for cardiovascular diseases
Q45868599Pulmonary venous hypertension and mechanical strain stimulate monocyte chemoattractant protein-1 release and structural remodelling of the lung in human and rodent chronic heart failure models
Q37822275Refilling Intracellular Calcium Stores
Q30604007Regulation of metabolism in individual mitochondria during excitation-contraction coupling
Q34757960Rescuing the failing heart by targeted gene transfer
Q37964927Reverse remodeling in heart failure--mechanisms and therapeutic opportunities
Q92175147Roles and mechanisms of SUMOylation on key proteins in myocardial ischemia/reperfusion injury
Q37418216SERCA2a gene therapy in heart failure: an anti-arrhythmic positive inotrope.
Q34025110SERCA2a gene transfer enhances eNOS expression and activity in endothelial cells
Q35183186SERCA2a gene transfer improves electrocardiographic performance in aged mdx mice
Q37676218Sarcoplasmic reticulum Ca(2+) ATPase as a therapeutic target for heart failure
Q38016716Sarcoplasmic reticulum and calcium cycling targeting by gene therapy
Q30654383Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure
Q36320912Stroke volume-to-wall stress ratio as a load-adjusted and stiffness-adjusted indicator of ventricular systolic performance in chronic loading
Q53580927Targeted gene transfer increases contractility and decreases oxygen cost of contractility in normal rat hearts.
Q35763705Targeting cardiomyocyte Ca2+ homeostasis in heart failure
Q37229784The cardiac sarcoplasmic/endoplasmic reticulum calcium ATPase: a potent target for cardiovascular diseases
Q90465039Unique Ca2+-Cycling Protein Abundance and Regulation Sustains Local Ca2+ Releases and Spontaneous Firing of Rabbit Sinoatrial Node Cells
Q37793527What Causes a Broken Heart—Molecular Insights into Heart Failure

Search more.