Mechanical and metabolic rescue in a type II diabetes model of cardiomyopathy by targeted gene transfer

scientific article published on 24 February 2006

Mechanical and metabolic rescue in a type II diabetes model of cardiomyopathy by targeted gene transfer is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.YMTHE.2006.01.002
P698PubMed publication ID16503203
P5875ResearchGate publication ID7274872

P2093author name stringRoger J Hajjar
Djamel Lebeche
Susumu Sakata
Federica del Monte
Elie R Chemaly
Li Fan Liang
Naoya Sakata
Yuri Sakata
Noboru Konishi
Miyako Takaki
Prabhu Padmanabhan
P2860cites workAltered calcium handling in experimental pressure-overload hypertrophy in the ferretQ69979818
Alterations of Sarcoplasmic Reticulum Proteins in Failing Human Dilated CardiomyopathyQ71974451
Characteristics of diabetes, blood pressure, and cardiac and renal complications in Otsuka Long-Evans Tokushima Fatty ratsQ73115380
Upregulation of Na(+)/Ca(2+) exchanger expression and function in an arrhythmogenic rabbit model of heart failureQ73204498
Alteration in left ventricular diastolic filling and accumulation of myocardial collagen at insulin-resistant prediabetic stage of a type II diabetic rat modelQ73492545
Angiotensin blockade improves cardiac and renal complications of type II diabetic ratsQ73879432
Cardiac Na/Ca exchange function in rabbit, mouse and man: what's the difference?Q78049992
Na/Ca exchange in heart failure: contractile dysfunction and arrhythmogenesisQ78719599
Restoration of contractile function in isolated cardiomyocytes from failing human hearts by gene transfer of SERCA2aQ22010899
Molecular basis of cardiac performance. Plasticity of the myocardium generated through protein isoform switchesQ24621025
Calcium fluxes involved in control of cardiac myocyte contractionQ28144050
FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac deathQ28183817
Cardiac excitation-contraction couplingQ28216347
Cardiac adenoviral S100A1 gene delivery rescues failing myocardiumQ28296403
Improvement in survival and cardiac metabolism after gene transfer of sarcoplasmic reticulum Ca(2+)-ATPase in a rat model of heart failureQ28354203
Prospects for gene therapy for heart failureQ33881236
In vivo ventricular gene delivery of a beta-adrenergic receptor kinase inhibitor to the failing heart reverses cardiac dysfunctionQ33936885
Myofilament calcium regulation in human myocardiumQ34074806
Targeting phospholamban by gene transfer in human heart failureQ34074819
Diabetes and atherosclerosis: epidemiology, pathophysiology, and managementQ34646074
Clinical use of inotropic therapy for heart failure: looking backward or forward? Part II: chronic inotropic therapyQ35186772
Left ventricular mechanoenergetics in small animalsQ35947413
Abrogation of ventricular arrhythmias in a model of ischemia and reperfusion by targeting myocardial calcium cyclingQ37682472
Spontaneous long-term hyperglycemic rat with diabetic complications. Otsuka Long-Evans Tokushima Fatty (OLETF) strainQ43619196
Left ventricular diastolic dysfunction in type 2 diabetes mellitus model ratsQ43826644
Progression of heart failure: is protein kinase a hyperphosphorylation of the ryanodine receptor a contributing factor?Q43862764
Overexpression of the sarcoplasmic reticulum Ca(2+)-ATPase improves myocardial contractility in diabetic cardiomyopathyQ43935483
beta2 adrenoceptor gene therapy ameliorates left ventricular dysfunction following cardiac surgeryQ45879401
Novel technique of aortic banding followed by gene transfer during hypertrophy and heart failureQ45885002
The functional effect of adenoviral Na+/Ca2+ exchanger overexpression in rabbit myocytes depends on the activity of the Na+/K+-ATPaseQ48746169
Relationship between Na+-Ca2+-exchanger protein levels and diastolic function of failing human myocardiumQ48749719
Increased oxygen cost of contractility in stunned myocardium of dogQ68033346
Abnormal intracellular calcium handling in myocardium from patients with end-stage heart failureQ69122833
P433issue5
P921main subjectcardiomyopathyQ847583
type 2 diabetesQ3025883
P304page(s)987-996
P577publication date2006-02-24
P1433published inMolecular TherapyQ15762400
P1476titleMechanical and metabolic rescue in a type II diabetes model of cardiomyopathy by targeted gene transfer
P478volume13

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cites work (P2860)
Q57799740A role for calcium in resistin transcriptional activation in diabetic hearts
Q35129485A systematic review of fetal genes as biomarkers of cardiac hypertrophy in rodent models of diabetes.
Q37766138Advances in gene-based therapy for heart failure
Q39493909Ca2+ cycling and new therapeutic approaches for heart failure
Q51414827Cardiac activation heat remains inversely dependent on temperature over the range 27-37°C.
Q27002459Cardiac dysfunction and oxidative stress in the metabolic syndrome: an update on antioxidant therapies
Q36977176Conditional increase in SERCA2a protein is able to reverse contractile dysfunction and abnormal calcium flux in established diabetic cardiomyopathy
Q36174452Diabetic cardiomyopathy: is resistin a culprit?
Q28395852Diabetic cardiomyopathy: signaling defects and therapeutic approaches
Q46730696Earlier onset of diabesity-Induced adverse cardiac remodeling in female compared to male mice
Q44087330Exercise training prevents the development of cardiac dysfunction in the low-dose streptozotocin diabetic rats fed a high-fat diet.
Q33489603Gene remodeling in type 2 diabetic cardiomyopathy and its phenotypic rescue with SERCA2a
Q45857145Gene therapy for diabetic cardiomyopathy: a new approach for a difficult problem
Q57823807Human Cardiac Gene Therapy
Q46291758Increased expression of SERCA in the hearts of transgenic mice results in increased oxidation of glucose
Q34279229Increased myocardial SERCA expression in early type 2 diabetes mellitus is insulin dependent: In vivo and in vitro data
Q37278004Interplay between impaired calcium regulation and insulin signaling abnormalities in diabetic cardiomyopathy
Q43110528Long-term cardiac-targeted RNA interference for the treatment of heart failure restores cardiac function and reduces pathological hypertrophy
Q36699924Mechanisms of impaired calcium handling underlying subclinical diastolic dysfunction in diabetes
Q37691385Overexpression of Sarcoendoplasmic Reticulum Calcium ATPase 2a Promotes Cardiac Sympathetic Neurotransmission via Abnormal Endoplasmic Reticulum and Mitochondria Ca2+ Regulation.
Q36228624Phospholamban Ablation Using CRISPR/Cas9 System Improves Mortality in a Murine Heart Failure Model
Q46921446Preservation of mechanical and energetic function after adenoviral gene transfer in normal rat hearts
Q35933316Restoration of mechanical and energetic function in failing aortic-banded rat hearts by gene transfer of calcium cycling proteins
Q34328371Role of ER stress in ventricular contractile dysfunction in type 2 diabetes
Q37418216SERCA2a gene therapy in heart failure: an anti-arrhythmic positive inotrope.
Q34025110SERCA2a gene transfer enhances eNOS expression and activity in endothelial cells
Q37676218Sarcoplasmic reticulum Ca(2+) ATPase as a therapeutic target for heart failure
Q36650350Small Molecular Allosteric Activator of the Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) Attenuates Diabetes and Metabolic Disorders
Q53580927Targeted gene transfer increases contractility and decreases oxygen cost of contractility in normal rat hearts.
Q37229784The cardiac sarcoplasmic/endoplasmic reticulum calcium ATPase: a potent target for cardiovascular diseases
Q47319449Transcoronary gene transfer of SERCA2a increases coronary blood flow and decreases cardiomyocyte size in a type 2 diabetic rat model

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