Receptor oligomerization in family B1 of G-protein-coupled receptors: focus on BRET investigations and the link between GPCR oligomerization and binding cooperativity

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Receptor oligomerization in family B1 of G-protein-coupled receptors: focus on BRET investigations and the link between GPCR oligomerization and binding cooperativity is …
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scholarly articleQ13442814

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P356DOI10.3389/FENDO.2012.00062
P932PMC publication ID3355942
P698PubMed publication ID22649424
P5875ResearchGate publication ID225079619

P50authorPierre De MeytsQ18209260
P2093author name stringRasmus Jorgensen
Sarah Norklit Roed
Anne Orgaard
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A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G proteinQ35778121
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Calcitonin and calcitonin receptor-like receptors: common themes with family B GPCRs?Q36153231
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Secretin receptor oligomers form intracellularly during maturation through receptor core domainsQ36826025
Computational studies of Family A and Family B GPCRsQ36883937
Incretin-based treatment of type 2 diabetes: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitorsQ36945112
Glucagon receptorsQ37091792
Dimerization in the absence of higher-order oligomerization of the G protein-coupled secretin receptorQ37177027
The incretin system and its role in type 2 diabetes mellitusQ37266863
Benefits and limitations of reducing glucagon action for the treatment of type 2 diabetesQ37360316
The apparent cooperativity of some GPCRs does not necessarily imply dimerization.Q37408661
Incretin-based therapy of type 2 diabetes mellitusQ37411508
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NMR structure and peptide hormone binding site of the first extracellular domain of a type B1 G protein-coupled receptorQ37511744
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Back to the future: revisiting parathyroid hormone and calcitonin control of bone remodelingQ37706351
PTH analogues and osteoporotic fracturesQ37772506
The therapeutic potential of targeting the glucagon-like peptide-2 receptor in gastrointestinal diseaseQ37840099
Glucagon antagonism as a potential therapeutic target in type 2 diabetesQ37880234
Regulation of glucagon secretion by incretinsQ37913515
The role of dysregulated glucagon secretion in type 2 diabetesQ37913523
Oligomerization of G protein-coupled receptors: biochemical and biophysical methods.Q37921841
Lateral Allosterism in the Glucagon Receptor Family: Glucagon-Like Peptide 1 Induces G-Protein-Coupled Receptor Heteromer FormationQ39438615
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Assembly and signaling of CRLR and RAMP1 complexes assessed by BRET.Q40132758
Opsin oligomerization in a heterologous cell systemQ40205844
Possible endogenous agonist mechanism for the activation of secretin family G protein-coupled receptorsQ40306029
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Rational design, synthesis, and biological evaluation of novel growth hormone releasing factor analoguesQ40614410
A peptide derived from a beta2-adrenergic receptor transmembrane domain inhibits both receptor dimerization and activation.Q41186190
Functional importance of a structurally distinct homodimeric complex of the family B G protein-coupled secretin receptorQ41883095
Lack of evidence for AT1R/B2R heterodimerization in COS-7, HEK293, and NIH3T3 cells: how common is the AT1R/B2R heterodimer?Q42806160
Silencing of secretin receptor function by dimerization with a misspliced variant secretin receptor in ductal pancreatic adenocarcinomaQ44138569
Negative cooperativity among beta-adrenergic receptors in frog erythrocyte membranesQ44182279
The alternatively spliced deltae13 transcript of the rabbit calcitonin receptor dimerizes with the C1a isoform and inhibits its surface expressionQ44397881
Increased AT(1) receptor heterodimers in preeclampsia mediate enhanced angiotensin II responsivenessQ46841539
Dimerization of corticotropin-releasing factor receptor type 1 is not coupled to ligand bindingQ46880025
Peptide agonist docking in the N-terminal ectodomain of a class II G protein-coupled receptor, the VPAC1 receptor. Photoaffinity, NMR, and molecular modelingQ46977928
P921main subjectG protein-coupled receptorQ38173
P304page(s)62
P577publication date2012-05-07
P1433published inFrontiers in EndocrinologyQ27723680
P1476titleReceptor oligomerization in family B1 of G-protein-coupled receptors: focus on BRET investigations and the link between GPCR oligomerization and binding cooperativity
P478volume3

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cites work (P2860)
Q27025870Action and therapeutic potential of oxyntomodulin
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Q38220597Moonlighting adenosine deaminase: a target protein for drug development
Q34781241PACAP induces the dimerization of PAC1 on the nucleus associated with the cAMP increase in the nucleus
Q42567375Receptor oligomerization: from early evidence to current understanding in class B GPCRs.
Q64226623Receptor-Receptor Interactions as a Widespread Phenomenon: Novel Targets for Drug Development?
Q34532319The N-Terminal HSDCIF Motif Is Required for Cell Surface Trafficking and Dimerization of Family B G Protein Coupled Receptor PAC1
Q28082755Transmembrane signal transduction by peptide hormones via family B G protein-coupled receptors
Q27001704Unraveling oxyntomodulin, GLP1's enigmatic brother

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