Illuminating the diversity of aromatic polyketide synthases in Aspergillus nidulans

scientific article

Illuminating the diversity of aromatic polyketide synthases in Aspergillus nidulans is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1021/JA3016395
P953full work available at URLhttps://europepmc.org/articles/pmc3357392?pdf=render
P932PMC publication ID3357392
P698PubMed publication ID22510154
P5875ResearchGate publication ID224283504

P7228access restriction statusopen accessQ232932
P50authorYi-Ming ChiangQ42389244
Berl R OakleyQ42389252
P2093author name stringClay C C Wang
James F Sanchez
Ruth Entwistle
Shu-Lin Chang
Manmeet Ahuja
Hsu-Hua Yeh
Hsien-Chun Lo
Mike B Praseuth
P2860cites workPhysically discrete beta-lactamase-type thioesterase catalyzes product release in atrochrysone synthesis by iterative type I polyketide synthaseQ84114188
Identification of the viridicatumtoxin and griseofulvin gene clusters from Penicillium aethiopicumQ21147075
Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzaeQ22122464
Structural basis for biosynthetic programming of fungal aromatic polyketide cyclizationQ27657897
Characterization of the Aspergillus nidulans monodictyphenone gene cluster.Q33768287
A genome-wide polyketide synthase deletion library uncovers novel genetic links to polyketides and meroterpenoids in Aspergillus nidulansQ33928023
Two induced fungal polyketide pathways converge into antiproliferative spiroanthronesQ33941464
Molecular genetic analysis of the orsellinic acid/F9775 gene cluster of Aspergillus nidulansQ33991955
Classification, prediction, and verification of the regioselectivity of fungal polyketide synthase product template domainsQ34003788
Fungal secondary metabolism - from biochemistry to genomicsQ34472162
A versatile and efficient gene-targeting system for Aspergillus nidulans.Q34587921
Pka, Ras and RGS protein interactions regulate activity of AflR, a Zn(II)2Cys6 transcription factor in Aspergillus nidulans.Q34618862
Phylogenomic analysis of type I polyketide synthase genes in pathogenic and saprobic ascomycetes.Q34790450
Big effects from small changes: possible ways to explore nature's chemical diversity.Q34906532
Unlocking fungal cryptic natural products.Q35003959
Unraveling polyketide synthesis in members of the genus AspergillusQ35032980
Recent advances in awakening silent biosynthetic gene clusters and linking orphan clusters to natural products in microorganisms.Q35052110
Genome-based deletion analysis reveals the prenyl xanthone biosynthesis pathway in Aspergillus nidulansQ35057853
Identification of a starter unit acyl-carrier protein transacylase domain in an iterative type I polyketide synthaseQ35130685
New insights into the formation of fungal aromatic polyketidesQ35235074
The ethanol utilization regulon of Aspergillus nidulans: the alcA-alcR system as a tool for the expression of recombinant proteinsQ35287925
Starter unit specificity directs genome mining of polyketide synthase pathways in fungiQ35435897
Sterigmatocystin biosynthesis in Aspergillus nidulans requires a novel type I polyketide synthaseQ35592757
Engineering of an "unnatural" natural product by swapping polyketide synthase domains in Aspergillus nidulansQ35954467
Two separate gene clusters encode the biosynthetic pathway for the meroterpenoids austinol and dehydroaustinol in Aspergillus nidulans.Q35954478
The current status of species recognition and identification in AspergillusQ36509356
Cloning of the polyketide synthase gene atX from Aspergillus terreus and its identification as the 6-methylsalicylic acid synthase gene by heterologous expressionQ36843061
Polyketides, proteins and genes in fungi: programmed nano-machines begin to reveal their secretsQ36854319
Identification and characterization of the asperthecin gene cluster of Aspergillus nidulansQ37023797
Intimate bacterial-fungal interaction triggers biosynthesis of archetypal polyketides in Aspergillus nidulansQ37321247
A gene cluster containing two fungal polyketide synthases encodes the biosynthetic pathway for a polyketide, asperfuranone, in Aspergillus nidulansQ37395784
Twenty-five coregulated transcripts define a sterigmatocystin gene cluster in Aspergillus nidulansQ37716071
Comparative characterization of fungal anthracenone and naphthacenedione biosynthetic pathways reveals an α-hydroxylation-dependent Claisen-like cyclization catalyzed by a dimanganese thioesterase.Q38592486
Deconstruction of iterative multidomain polyketide synthase function.Q40794040
Chromatin-level regulation of biosynthetic gene clustersQ41371805
Genomics-driven discovery of PKS-NRPS hybrid metabolites from Aspergillus nidulansQ42615072
Identification of Claisen cyclase domain in fungal polyketide synthase WA, a naphthopyrone synthase of Aspergillus nidulansQ43543858
Initial characterization of a type I fatty acid synthase and polyketide synthase multienzyme complex NorS in the biosynthesis of aflatoxin B(1).Q44152735
Multifactorial induction of an orphan PKS-NRPS gene cluster in Aspergillus terreusQ44392953
Triggering cryptic natural product biosynthesis in microorganismsQ61774190
Fusion PCR and gene targeting in Aspergillus nidulansQ62658531
P433issue19
P407language of work or nameEnglishQ1860
P921main subjectalternariolQ410677
Aspergillus nidulansQ683881
biodiversityQ47041
Polyketide synthaseQ62680893
Putative nonribosomal peptide synthetase (NRPS)-like enzymeQ62684686
C2H2 zinc-finger transcription factor involved in cation homeostasisQ62684743
Putative hybrid polyketide synthase-nonribosomal peptide synthase (PKS-NRPS)Q62689401
Putative Zn(II)2Cys6 transcription factorQ62689413
putative transcription factorQ62690214
Putative Zn(II)2Cys6 transcription factorQ62690234
Putative single-module nonribosomal peptide synthetase (NRPS)Q62690261
methyl orsellinic acidQ72466618
2,5-DimethylresorcinolQ75064028
3-(2,4-dihydroxy-6-methylbenzyl)-orsellinaldehydeQ77385126
2,4-dihydroxy-3-methyl-6-(2-oxopropyl)benzaldehydeQ77419877
2-ethyl-4,6-dihydroxy-3,5-dimethylbenzaldehydeQ77562228
cichorineQ27104923
3,5-dimethylorsellinic acidQ27225434
2,4-dihydroxy-6-methylbenzaldehydeQ27251742
Putative Zn(II)2Cys6 transcription factorQ62664271
Putative Zn(II)2Cys6 transcription factorQ62664280
Putative polyketide synthaseQ62664289
Putative polyketide synthaseQ62667631
Putative polyketide synthaseQ62667662
Asperfuranone cluster transcription factor afoAQ62667726
Putative Zn(II)2Cys6 transcription factorQ62669423
Putative polyketide synthaseQ62669469
Polyketide synthaseQ62670767
Putative C6 zinc finger transcription factorQ62670774
transcription coactivator, putativeQ62670785
putative transcription factorQ62671898
putative transcription factorQ62671904
Putative polyketide synthase (PKS)Q62671923
putative transcription factorQ62673174
Putative nonribosomal peptide synthase (NRPS)-like enzymeQ62673179
putative transcription factorQ62674225
putative transcription factorQ62674231
Putative polyketide synthaseQ62674254
Putative polyketide synthaseQ62674269
Putative Zn(II)2Cys6 transcription factorQ62674274
putative transcription factorQ62677622
Putative nonribosomal peptide synthase (NRPS)Q62677703
putative transcription factorQ62677752
Putative polyketide synthase (PKS)Q62677789
Putative non-ribosomal peptide synthase (NRPS)Q62679542
C2H2 and Zn(2)-Cys(6) DNA binding transcription factor, putativeQ62679583
Putative polyketide synthaseQ62679621
Putative Zn(II)2Cys6 transcription factorQ62679631
Fatty acid synthetase subunit, putativeQ62679665
Fatty acyl-CoA synthase, putativeQ62679672
Polyketide synthaseQ62649251
putative transcription factorQ62650409
Putative nonribosomal peptide synthase (NRPS)-like enzymeQ62650420
Putative Zn(II)2Cys6 transcription factorQ62650461
Putative nonribosomal peptide synthetase (NRPS)-like enzymeQ62653791
Putative Zn(II)2Cys6 transcription factorQ62653795
Putative Zn(II)2Cys6 transcription factorQ62653799
Putative Zn(II)2Cys6 transcription factorQ62655232
Putative Zn(II)2Cys6 transcription factorQ62655246
Putative Zn(II)2Cys6 transcription factorQ62655249
Putative nonribosomal peptide synthetaseQ62655272
Putative nonribosomal peptide synthetaseQ62655276
Putative Zn(II)2Cys6 transcription factorQ62656592
Putative polyketide synthaseQ62656596
Beta-lactamase-type thioesteraseQ62656598
Putative Zn(II)2Cys6 transcription factorQ62656623
Putative polyketide synthaseQ62659307
Putative polyketide synthaseQ62659355
putative transcription factorQ62659357
P1104number of pages10
P6954online access statusopen accessQ232932
P304page(s)8212-8221
P577publication date2012-05-01
P1433published inJournal of the American Chemical SocietyQ898902
P1476titleIlluminating the diversity of aromatic polyketide synthases in Aspergillus nidulans
P478volume134