| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1007990327 |
| P356 | DOI | 10.1038/NRMICRO2465 |
| P953 | full work available at URL | https://europepmc.org/articles/pmc3181163?pdf=render |
| https://europepmc.org/articles/PMC3181163 | ||
| https://europepmc.org/articles/PMC3181163?pdf=render | ||
| https://doi.org/10.1038/nrmicro2465 | ||
| http://www.nature.com/articles/nrmicro2465.pdf | ||
| http://www.nature.com/articles/nrmicro2465 | ||
| P932 | PMC publication ID | 3181163 |
| P698 | PubMed publication ID | 21079635 |
| P5875 | ResearchGate publication ID | 47794944 |
| P2093 | author name string | Craig A. Townsend | |
| Jason M. Crawford | |||
| P2860 | cites work | Biosynthesis of norsolorinic acid and averufin: substrate specificity of norsolorinic acid synthase | Q104885558 |
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| bikaverin | Q27105942 | ||
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| The crystal structure of a mammalian fatty acid synthase | Q27651988 | ||
| Crystal Structure of the Erythromycin Polyketide Synthase Dehydratase | Q27652658 | ||
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| Structure of a dehydratase-isomerase from the bacterial pathway for biosynthesis of unsaturated fatty acids: two catalytic activities in one active site | Q27733371 | ||
| Alpha/beta hydrolase fold enzymes: the family keeps growing | Q28140985 | ||
| The chalcone synthase superfamily of type III polyketide synthases | Q28183088 | ||
| Mechanism of the beta-ketoacyl synthase reaction catalyzed by the animal fatty acid synthase | Q28219064 | ||
| An antibiotic factory caught in action | Q28275079 | ||
| Crystal structure of a bacterial type III polyketide synthase and enzymatic control of reactive polyketide intermediates | Q28504082 | ||
| Functional Characterization of the Biosynthesis of Radicicol, an Hsp90 Inhibitor Resorcylic Acid Lactone from Chaetomium chiversii | Q29032069 | ||
| Solvent effects on keto-enol equilibria: tests of quantitative models | Q29400539 | ||
| Adaptations of the helix-grip fold for ligand binding and catalysis in the START domain superfamily. | Q30328049 | ||
| Genes for the biosynthesis of the fungal polyketides hypothemycin from Hypomyces subiculosus and radicicol from Pochonia chlamydosporia | Q33345330 | ||
| Melanin is an essential component for the integrity of the cell wall of Aspergillus fumigatus conidia | Q33496334 | ||
| Non-heme iron oxygenases generate natural structural diversity in carbapenem antibiotics | Q33519127 | ||
| Cyclization of aromatic polyketides from bacteria and fungi | Q33910335 | ||
| Classification, prediction, and verification of the regioselectivity of fungal polyketide synthase product template domains | Q34003788 | ||
| Polyketide biosynthesis: a millennium review | Q34362914 | ||
| Fungal secondary metabolism - from biochemistry to genomics | Q34472162 | ||
| A biosynthetic classification of fungal and streptomycete fused-ring aromatic polyketides | Q34518315 | ||
| Phylogenomic analysis of type I polyketide synthase genes in pathogenic and saprobic ascomycetes. | Q34790450 | ||
| Unlocking fungal cryptic natural products. | Q35003959 | ||
| Biosynthesis of fungal melanins and their importance for human pathogenic fungi | Q35079260 | ||
| Polyketide biosynthesis beyond the type I, II and III polyketide synthase paradigms | Q35114475 | ||
| Identification of a starter unit acyl-carrier protein transacylase domain in an iterative type I polyketide synthase | Q35130685 | ||
| Synthetic strategy of nonreducing iterative polyketide synthases and the origin of the classical "starter-unit effect". | Q35237614 | ||
| Acyl-carrier protein-phosphopantetheinyltransferase partnerships in fungal fatty acid synthases | Q35296323 | ||
| Starter unit specificity directs genome mining of polyketide synthase pathways in fungi | Q35435897 | ||
| Enzyme reactions and genes in aflatoxin biosynthesis | Q35691590 | ||
| A method for prediction of the locations of linker regions within large multifunctional proteins, and application to a type I polyketide synthase. | Q36104021 | ||
| Advances in cloning, functional analysis and heterologous expression of fungal polyketide synthase genes | Q36485111 | ||
| The type I fatty acid and polyketide synthases: a tale of two megasynthases | Q36489362 | ||
| A polyketide macrolactone synthase from the filamentous fungus Gibberella zeae | Q36609099 | ||
| Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork | Q36724719 | ||
| Natural products of filamentous fungi: enzymes, genes, and their regulation | Q36772397 | ||
| TP53 mutations and hepatocellular carcinoma: insights into the etiology and pathogenesis of liver cancer | Q36777331 | ||
| Polyketides, proteins and genes in fungi: programmed nano-machines begin to reveal their secrets | Q36854319 | ||
| New biosynthetic step in the melanin pathway of Wangiella (Exophiala) dermatitidis: evidence for 2-acetyl-1,3,6,8-Tetrahydroxynaphthalene as a novel precursor | Q36939039 | ||
| Identification and characterization of the asperthecin gene cluster of Aspergillus nidulans | Q37023797 | ||
| Aspergillus has distinct fatty acid synthases for primary and secondary metabolism | Q37055265 | ||
| Engineered biosynthesis of bacterial aromatic polyketides in Escherichia coli | Q37081542 | ||
| Color me bad: microbial pigments as virulence factors | Q37346342 | ||
| Heterologous expression systems for polyketide synthases | Q37379780 | ||
| Biosynthesis of aromatic polyketides in bacteria | Q37416691 | ||
| Bacterial fatty acid synthesis and its relationships with polyketide synthetic pathways | Q37442104 | ||
| The biosynthetic logic of polyketide diversity | Q37513922 | ||
| PKS and NRPS release mechanisms | Q37683524 | ||
| Functional analysis of fungal polyketide biosynthesis genes | Q37702785 | ||
| Enzymatic synthesis of resorcylic acid lactones by cooperation of fungal iterative polyketide synthases involved in hypothemycin biosynthesis | Q40271160 | ||
| HypC, the anthrone oxidase involved in aflatoxin biosynthesis | Q40527307 | ||
| Complete reconstitution of a highly reducing iterative polyketide synthase | Q40705862 | ||
| Deconstruction of iterative multidomain polyketide synthase function. | Q40794040 | ||
| Enzymatic synthesis of aromatic polyketides using PKS4 from Gibberella fujikuroi | Q41996210 | ||
| Characterization of two polyketide synthase genes involved in zearalenone biosynthesis in Gibberella zeae | Q42003278 | ||
| Production of octaketide polyenes by the calicheamicin polyketide synthase CalE8: implications for the biosynthesis of enediyne core structures | Q42144169 | ||
| Redirecting the cyclization steps of fungal polyketide synthase. | Q42405821 | ||
| Multiple convergence in polyketide biosynthesis: a third folding mode to the anthraquinone chrysophanol | Q43249853 | ||
| Identification of Claisen cyclase domain in fungal polyketide synthase WA, a naphthopyrone synthase of Aspergillus nidulans | Q43543858 | ||
| Pentaketide melanin biosynthesis in Aspergillus fumigatus requires chain-length shortening of a heptaketide precursor | Q43606323 | ||
| Initial characterization of a type I fatty acid synthase and polyketide synthase multienzyme complex NorS in the biosynthesis of aflatoxin B(1). | Q44152735 | ||
| In vitro analysis of type II polyketide synthase | Q46052983 | ||
| Fungal type I polyketide synthases. | Q46052998 | ||
| Biochemical characterization of the minimal polyketide synthase domains in the lovastatin nonaketide synthase LovB. | Q46337180 | ||
| Dissecting the catalytic triad of a serine protease | Q46366429 | ||
| Hexanoate synthase, a specialized type I fatty acid synthase in aflatoxin B1 biosynthesis | Q46780201 | ||
| Studies on the mechanism of fatty acid synthesis. XXIV. The acetyl- and malonyltransacylase activities of pigeon liver fatty acid synthetase. | Q47773181 | ||
| Covalent linkage mediates communication between ACP and TE domains in modular polyketide synthases | Q47839025 | ||
| Ketosynthase domain probes identify two subclasses of fungal polyketide synthase genes | Q47957861 | ||
| The Aspergillus parasiticus polyketide synthase gene pksA, a homolog of Aspergillus nidulans wA, is required for aflatoxin B1 biosynthesis | Q48071340 | ||
| Demonstration of the catalytic roles and evidence for the physical association of type I fatty acid synthases and a polyketide synthase in the biosynthesis of aflatoxin B1. | Q52521222 | ||
| The polyketide synthase gene pks4 from Gibberella fujikuroi encodes a key enzyme in the biosynthesis of the red pigment bikaverin. | Q52548084 | ||
| Catalytic relationships between type I and type II iterative polyketide synthases: The Aspergillus parasiticus norsolorinic acid synthase. | Q54452461 | ||
| The architecture of the animal fatty acid synthetase complex. IV. Mapping of active centers and model for the mechanism of action | Q57020285 | ||
| Chapter 1 Introduction to Polyketide Biosynthesis | Q57310228 | ||
| Modulation of Polyketide Synthase Activity by Accessory Proteins During Lovastatin Biosynthesis | Q60480995 | ||
| Triggering cryptic natural product biosynthesis in microorganisms | Q61774190 | ||
| Don't Classify Polyketide Synthases | Q61859759 | ||
| Design and utility of oligonucleotide gene probes for fungal polyketide synthases | Q62659019 | ||
| Heterologous expression and product identification of Colletotrichum lagenarium polyketide synthase encoded by the PKS1 gene involved in melanin biosynthesis | Q73028544 | ||
| Enzymatic synthesis of 1,3,6,8-tetrahydroxynaphthalene solely from malonyl coenzyme A by a fungal iterative type I polyketide synthase PKS1 | Q74061867 | ||
| Pentaketide resorcylic acid synthesis by type III polyketide synthase from Neurospora crassa | Q79996247 | ||
| Unprecedented mechanism of chain length determination in fungal aromatic polyketide synthases | Q80482860 | ||
| One pathway, many products | Q80494454 | ||
| 13C AND 2H labelling studies on the biosynthesis of scytalone in phialaphora lagerbergII | Q104867154 | ||
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 879-889 | |
| P577 | publication date | 2010-12-01 | |
| P1433 | published in | Nature Reviews Microbiology | Q1071797 |
| P1476 | title | New insights into the formation of fungal aromatic polyketides | |
| P478 | volume | 8 |
| Q54940115 | A MYST Histone Acetyltransferase Modulates Conidia Development and Secondary Metabolism in Pestalotiopsis microspora, a Taxol Producer. |
| Q92392545 | A detailed in silico analysis of secondary metabolite biosynthesis clusters in the genome of the broad host range plant pathogenic fungus Sclerotinia sclerotiorum |
| Q46091315 | A few shared up-regulated genes may influence conidia to yeast transformation in dimorphic fungal pathogens |
| Q46310396 | A fruitful decade for fungal polyketides from 2007 to 2016: antimicrobial activity, chemotaxonomy and chemodiversity. |
| Q34385351 | A genome-wide survey of the secondary metabolite biosynthesis genes in the wheat pathogen Parastagonospora nodorum |
| Q92173188 | A polyketide synthase gene cluster associated with the sexual reproductive cycle of the banana pathogen, Pseudocercospora fijiensis |
| Q26863697 | Aflatoxin and deconstruction of type I, iterative polyketide synthase function |
| Q41473688 | Analysis of the Sequences, Structures, and Functions of Product-Releasing Enzyme Domains in Fungal Polyketide Synthases |
| Q89980587 | Anti-melanogenic activity of Myristica fragrans extract against Aspergillus fumigatus using phenotypic based screening |
| Q58109685 | Antimicrobial aromatic polyketides: a review of their antimicrobial properties and potential use in plant disease control |
| Q26822686 | Beyond DNA origami: the unfolding prospects of nucleic acid nanotechnology |
| Q35637445 | Bioinformatical analysis of the sequences, structures and functions of fungal polyketide synthase product template domains |
| Q38195645 | Biosynthesis of mycobacterial lipids by polyketide synthases and beyond |
| Q61450373 | Biosynthetic Gene Content of the 'Perfume Lichens' and |
| Q36770494 | Biosynthetic investigation of phomopsins reveals a widespread pathway for ribosomal natural products in Ascomycetes |
| Q36488484 | Characterization of a fungal thioesterase having Claisen cyclase and deacetylase activities in melanin biosynthesis. |
| Q28704556 | Characterization of the biosynthetic genes for 10,11-dehydrocurvularin, a heat shock response-modulating anticancer fungal polyketide from Aspergillus terreus |
| Q46392267 | Collaborative Biosynthesis of Maleimide- and Succinimide-Containing Natural Products by Fungal Polyketide Megasynthases. |
| Q30413205 | Combinatorial biosynthesis of polyketides--a perspective. |
| Q42080622 | Combinatorial domain swaps provide insights into the rules of fungal polyketide synthase programming and the rational synthesis of non-native aromatic products |
| Q38592486 | Comparative characterization of fungal anthracenone and naphthacenedione biosynthetic pathways reveals an α-hydroxylation-dependent Claisen-like cyclization catalyzed by a dimanganese thioesterase. |
| Q41884208 | Complexity generation in fungal polyketide biosynthesis: a spirocycle-forming P450 in the concise pathway to the antifungal drug griseofulvin. |
| Q38034159 | Current development of microfluidic immunosensing approaches for mycotoxin detection via capillary electromigration and lateral flow technology |
| Q34341202 | Demonstration of starter unit interprotein transfer from a fatty acid synthase to a multidomain, nonreducing polyketide synthase |
| Q34120045 | Diversity-oriented combinatorial biosynthesis of benzenediol lactone scaffolds by subunit shuffling of fungal polyketide synthases |
| Q92833467 | Docking analysis of hexanoic acid and quercetin with seven domains of polyketide synthase A provided insight into quercetin-mediated aflatoxin biosynthesis inhibition in Aspergillus flavus |
| Q27728317 | Domain Organization and Active Site Architecture of a Polyketide Synthase C-methyltransferase |
| Q41903321 | Effect of Various Compounds Blocking the Colony Pigmentation on the Aflatoxin B1 Production by Aspergillus flavus. |
| Q59800881 | Engineering of the Filamentous Fungus as Cell Factory for Natural Products |
| Q34273067 | Engineering synthetic recursive pathways to generate non-natural small molecules |
| Q52880674 | Evolution of structural diversity of trichothecenes, a family of toxins produced by plant pathogenic and entomopathogenic fungi. |
| Q28545284 | Expanding our understanding of sequence-function relationships of type II polyketide biosynthetic gene clusters: bioinformatics-guided identification of Frankiamicin A from Frankia sp. EAN1pec |
| Q38233467 | Explorations of fungal biosynthesis of reduced polyketides - a personal viewpoint |
| Q53478104 | Functional and Structural Analysis of Programmed C-Methylation in the Biosynthesis of the Fungal Polyketide Citrinin. |
| Q38365647 | Fungal genome sequencing: basic biology to biotechnology |
| Q44466276 | Genetic localization and in vivo characterization of a Monascus azaphilone pigment biosynthetic gene cluster |
| Q38222595 | Genetics of Polyketide Metabolism in Aspergillus nidulans |
| Q39227817 | Genome editing approaches: manipulating of lovastatin and taxol synthesis of filamentous fungi by CRISPR/Cas9 system |
| Q92177511 | Genome mining and biosynthesis of a polyketide from a biofertilizer fungus that can facilitate reductive iron assimilation in plant |
| Q34703730 | Hirsutellones and beyond: figuring out the biological and synthetic logics toward chemical complexity in fungal PKS-NRPS compounds. |
| Q36418855 | Identification of a Polyketide Synthase Gene in the Synthesis of Phleichrome of the Phytopathogenic Fungus Cladosporium phlei |
| Q28481163 | Identification of a polyketide synthase required for alternariol (AOH) and alternariol-9-methyl ether (AME) formation in Alternaria alternata |
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| Q35906588 | Interrogation of global active site occupancy of a fungal iterative polyketide synthase reveals strategies for maintaining biosynthetic fidelity |
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| Q34778268 | Modeling linear and cyclic PKS intermediates through atom replacement. |
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