Compartmentalized phosphorylation of IAP by protein kinase A regulates cytoprotection

scientific article

Compartmentalized phosphorylation of IAP by protein kinase A regulates cytoprotection is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.MOLCEL.2007.06.004
P932PMC publication ID1986705
P698PubMed publication ID17612487
P5875ResearchGate publication ID6226290

P50authorDario C AltieriQ98158352
P2093author name stringTakehiko Dohi
Fang Xia
P2860cites workStructure of the human anti-apoptotic protein survivin reveals a dimeric arrangementQ22254394
Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivinQ24290497
HBXIP functions as a cofactor of survivin in apoptosis suppressionQ24303423
Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1Q24308005
cIAP1 Localizes to the nuclear compartment and modulates the cell cycleQ24338725
Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the familyQ24670396
CD95's deadly mission in the immune systemQ28142072
A structural view of mitochondria-mediated apoptosisQ28185843
Validating survivin as a cancer therapeutic targetQ28201382
Separating the anti-apoptotic and mitotic roles of survivinQ28261657
Survivin splice variants regulate the balance between proliferation and cell deathQ28305497
A dynamic mechanism for AKAP binding to RII isoforms of cAMP-dependent protein kinaseQ28574420
The biochemistry of apoptosisQ29547741
The Bcl2 family: regulators of the cellular life-or-death switchQ29614982
AKAP signalling complexes: focal points in space and timeQ29618533
Protein translocation in apoptosisQ33730384
Involvement of microtubules in the regulation of Bcl2 phosphorylation and apoptosis through cyclic AMP-dependent protein kinaseQ33774328
PKA: a portrait of protein kinase dynamicsQ34306110
Mutations of the gene encoding the protein kinase A type I-alpha regulatory subunit in patients with the Carney complex.Q34510622
Dissecting the circuitry of protein kinase A and cAMP signaling in cancer genesis: antisense, microarray, gene overexpression, and transcription factor decoy.Q34741074
The essential role of RI alpha in the maintenance of regulated PKA activityQ34741109
Protein kinase A as target for novel integrated strategies of cancer therapy.Q34741171
Competition and compensation: coupled to death in development and cancerQ34803139
Apoptosis-targeted therapies for cancerQ35057060
The AMP-activated protein kinase pathway--new players upstream and downstream.Q35930365
Identification of a tumour suppressor network opposing nuclear Akt functionQ35991130
PP2A: the expected tumor suppressorQ36015508
The survival kinases Akt and Pim as potential pharmacological targetsQ36274952
Reawakening the cellular death program in neoplasia through the therapeutic blockade of IAP functionQ36274969
The case for survivin as a regulator of microtubule dynamics and cell-death decisionsQ36578149
The case for Survivin as mitotic regulatorQ36589633
Mitochondrial survivin inhibits apoptosis and promotes tumorigenesis.Q37574259
B56-associated protein phosphatase 2A is required for survival and protects from apoptosis in Drosophila melanogasterQ39674654
Protein phosphatase 2A enhances the proapoptotic function of Bax through dephosphorylationQ40282861
An IAP-IAP complex inhibits apoptosisQ40541576
Phosphorylation of Par-4 by protein kinase A is critical for apoptosisQ40891090
Survivin exists in immunochemically distinct subcellular pools and is involved in spindle microtubule functionQ43893446
Down-regulation of regulatory subunit type 1A of protein kinase A leads to endocrine and other tumorsQ45190242
Phosphorylation of the pro-apoptotic protein BAD on serine 155, a novel site, contributes to cell survivalQ73292075
Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase AQ77406620
A JNK-Dependent Pathway Is Required for TNFα-Induced ApoptosisQ79129693
Molecular basis of AKAP specificity for PKA regulatory subunitsQ79326012
P433issue1
P921main subjectphosphorylationQ242736
P304page(s)17-28
P577publication date2007-07-01
P1433published inMolecular CellQ3319468
P1476titleCompartmentalized phosphorylation of IAP by protein kinase A regulates cytoprotection
P478volume27

Reverse relations

cites work (P2860)
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Q60922861CCAR2/DBC1 and Hsp60 Positively Regulate Expression of Survivin in Neuroblastoma Cells
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Q34539588cAMP initiates early phase neuron-like morphology changes and late phase neural differentiation in mesenchymal stem cells
Q54647670p21 does not protect cancer cells from apoptosis induced by nongenotoxic p53 activation

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