| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1026438232 |
| P356 | DOI | 10.1186/S12891-016-1055-2 |
| P932 | PMC publication ID | 4858923 |
| P698 | PubMed publication ID | 27150598 |
| P2093 | author name string | Akari Suzuki | |
| Kazuhiko Yamamoto | |||
| Ryo Yamada | |||
| Tetsuji Sawada | |||
| Yuta Kochi | |||
| Keishi Fujio | |||
| Hirofumi Shoda | |||
| Yu Seri | |||
| P2860 | cites work | Detailed analysis of the variability of peptidylarginine deiminase type 4 in German patients with rheumatoid arthritis: a case-control study | Q21195665 |
| Histone deimination antagonizes arginine methylation | Q24302163 | ||
| Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4 | Q24538382 | ||
| Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies | Q24564876 | ||
| The role of citrullinated proteins suggests a novel mechanism in the pathogenesis of multiple sclerosis | Q24676878 | ||
| Citrullinated proteins have increased immunogenicity and arthritogenicity and their presence in arthritic joints correlates with disease severity | Q24816615 | ||
| Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis | Q27653688 | ||
| Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis | Q28183279 | ||
| Nuclear localization of peptidylarginine deiminase V and histone deimination in granulocytes | Q28210002 | ||
| A functional haplotype of the PADI4 gene associated with rheumatoid arthritis in a Japanese population is not associated in a United Kingdom population | Q28255873 | ||
| Chromosome 12 breakpoints are cytogenetically different in benign and malignant lipogenic tumors: localization of breakpoints in lipoma to 12q15 and in myxoid liposarcoma to 12q13.3 | Q28267219 | ||
| Association between PADI4 and rheumatoid arthritis: a replication study | Q28275244 | ||
| Human PAD4 regulates histone arginine methylation levels via demethylimination | Q28280359 | ||
| Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci | Q28281906 | ||
| Cytokines in the pathogenesis of rheumatoid arthritis | Q28303865 | ||
| Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population | Q28943303 | ||
| A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese | Q28943458 | ||
| The major synovial targets of the rheumatoid arthritis-specific antifilaggrin autoantibodies are deiminated forms of the alpha- and beta-chains of fibrin | Q32133798 | ||
| Abnormal accumulation of citrullinated proteins catalyzed by peptidylarginine deiminase in hippocampal extracts from patients with Alzheimer's disease. | Q33211729 | ||
| Antibodies against cyclic citrullinated peptide and IgA rheumatoid factor predict the development of rheumatoid arthritis | Q44616885 | ||
| Citrullination of self-proteins and autoimmunity | Q44967035 | ||
| Localization of peptidylarginine deiminase 4 (PADI4) and citrullinated protein in synovial tissue of rheumatoid arthritis | Q45091885 | ||
| Citrullinated fibrinogen inhibits thrombin-catalysed fibrin polymerization. | Q46516349 | ||
| PADI4 polymorphisms are not associated with rheumatoid arthritis in the Spanish population | Q46584884 | ||
| Posttranslational protein modifications, apoptosis, and the bypass of tolerance to autoantigens | Q47849301 | ||
| PADI4 polymorphism predisposes male smokers to rheumatoid arthritis | Q58234815 | ||
| Association between HLA class II genes and autoantibodies to cyclic citrullinated peptides (CCPs) influences the severity of rheumatoid arthritis | Q58234987 | ||
| Regulation of histone modification and chromatin structure by the p53–PADI4 pathway | Q61207292 | ||
| Low-grade fibromyxoid sarcoma and hyalinizing spindle cell tumor with giant rosettes share a common t(7;16)(q34;p11) translocation | Q73911552 | ||
| A functional haplotype of the PADI4 gene associated with increased rheumatoid arthritis susceptibility in Koreans | Q82132463 | ||
| Murine bone marrow-derived macrophages | Q83529516 | ||
| Epidemiology, pathophysiology, and diagnosis of rheumatoid arthritis: A Synopsis | Q85235423 | ||
| Smoking, rheumatoid factor isotypes and severity of rheumatoid arthritis | Q95717263 | ||
| The inhibitory effect against collagen-induced arthritis by Schistosoma japonicum infection is infection stage-dependent | Q33600341 | ||
| Different patterns of associations with anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis in the extended major histocompatibility complex region | Q33868008 | ||
| Genome-wide analysis reveals PADI4 cooperates with Elk-1 to activate c-Fos expression in breast cancer cells. | Q33926858 | ||
| Peptidylarginine deiminase 4 contributes to tumor necrosis factor α-induced inflammatory arthritis | Q34105680 | ||
| Preferential deimination of keratin K1 and filaggrin during the terminal differentiation of human epidermis | Q34394482 | ||
| Peptidylarginine deiminase 2 suppresses inhibitory {kappa}B kinase activity in lipopolysaccharide-stimulated RAW 264.7 macrophages | Q34400787 | ||
| Association of CD40 with rheumatoid arthritis confirmed in a large UK case-control study | Q34436443 | ||
| Identification of PADI2 as a potential breast cancer biomarker and therapeutic target | Q34461456 | ||
| Influence of HLA-DR genes on the production of rheumatoid arthritis-specific autoantibodies to citrullinated fibrinogen | Q34463613 | ||
| Antibodies against citrullinated proteins enhance tissue injury in experimental autoimmune arthritis | Q34498921 | ||
| PADI4 and HLA-DRB1 are genetic risks for radiographic progression in RA patients, independent of ACPA status: results from the IORRA cohort study | Q34664095 | ||
| N-α-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide, a protein arginine deiminase inhibitor, reduces the severity of murine collagen-induced arthritis. | Q34904630 | ||
| Suppression of colitis in mice by Cl-amidine: a novel peptidylarginine deiminase inhibitor | Q35057027 | ||
| A family based study shows no association between rheumatoid arthritis and the PADI4 gene in a white French population | Q35555382 | ||
| Inhibitors and inactivators of protein arginine deiminase 4: functional and structural characterization. | Q35659250 | ||
| Use of a multiethnic approach to identify rheumatoid- arthritis-susceptibility loci, 1p36 and 17q12 | Q35843222 | ||
| Clinical and pathophysiological significance of the autoimmune response to citrullinated proteins in rheumatoid arthritis | Q35979168 | ||
| Myocardial citrullination in rheumatoid arthritis: a correlative histopathologic study. | Q36085051 | ||
| PAD4 is not essential for disease in the K/BxN murine autoantibody-mediated model of arthritis | Q36245934 | ||
| Histone arginine methylation and its dynamic regulation | Q36250971 | ||
| Autoimmunity to type II collagen an experimental model of arthritis | Q36335891 | ||
| A disease-associated PTPN22 variant promotes systemic autoimmunity in murine models | Q36802757 | ||
| Citrullinated fibronectin inhibits apoptosis and promotes the secretion of pro-inflammatory cytokines in fibroblast-like synoviocytes in rheumatoid arthritis | Q36907713 | ||
| Autoimmune diseases: insights from genome-wide association studies | Q37292877 | ||
| Rheumatoid arthritis and smoking: putting the pieces together | Q37350863 | ||
| The genetics of autoimmune diseases: a networked perspective | Q37629146 | ||
| Ethnogenetic heterogeneity of rheumatoid arthritis-implications for pathogenesis | Q37710382 | ||
| The cytokeratin filament-aggregating protein filaggrin is the target of the so-called "antikeratin antibodies," autoantibodies specific for rheumatoid arthritis | Q40304964 | ||
| Immunoblotting detection of so-called 'antikeratin antibodies': a new assay for the diagnosis of rheumatoid arthritis | Q41279839 | ||
| Expression and activity of citrullinating peptidylarginine deiminase enzymes in monocytes and macrophages | Q41855355 | ||
| The epitopes targeted by the rheumatoid arthritis-associated antifilaggrin autoantibodies are posttranslationally generated on various sites of (pro)filaggrin by deimination of arginine residues | Q42689767 | ||
| A mutation in KCNJ11 causing human hyperinsulinism (Y12X) results in a glucose-intolerant phenotype in the mouse | Q42943015 | ||
| Granulocyte macrophage colony-stimulating factor: a new putative therapeutic target in multiple sclerosis. | Q42944465 | ||
| Reduced incidence and severity of experimental autoimmune arthritis in mice expressing catalytically inactive A disintegrin and metalloproteinase 8 (ADAM8). | Q43279669 | ||
| Specific presence of intracellular citrullinated proteins in rheumatoid arthritis synovium: relevance to antifilaggrin autoantibodies | Q43772895 | ||
| Smoking increases rheumatoid arthritis susceptibility in individuals carrying the HLA-DRB1 shared epitope, regardless of rheumatoid factor or anti-cyclic citrullinated peptide antibody status | Q44264832 | ||
| Citrullination of synovial proteins in murine models of rheumatoid arthritis | Q44586791 | ||
| P921 | main subject | knockout mouse | Q1364740 |
| P304 | page(s) | 205 | |
| P577 | publication date | 2016-05-05 | |
| P1433 | published in | BMC Musculoskeletal Disorders | Q15751716 |
| P1476 | title | Decreased severity of experimental autoimmune arthritis in peptidylarginine deiminase type 4 knockout mice | |
| P478 | volume | 17 |
| Q90597865 | HIF1α inhibition facilitates Leflunomide-AHR-CRP signaling to attenuate bone erosion in CRP-aberrant rheumatoid arthritis |
| Q92006207 | IL-6-PAD4 axis in the earliest phase of arthritis in knock-in gp130F759 mice, a model for rheumatoid arthritis |
| Q33853885 | Identification of Padi2 as a novel angiogenesis-regulating gene by genome association studies in mice. |
| Q64077474 | Increased peptidylarginine deiminases expression during the macrophage differentiation and participated inflammatory responses |
| Q92072326 | Neutrophil Extracellular Traps in Autoimmunity and Allergy: Immune Complexes at Work |
| Q33811944 | Neutrophil extracellular traps exacerbate Th1-mediated autoimmune responses in rheumatoid arthritis by promoting DC maturation |
| Q93270547 | PAD enzymes in rheumatoid arthritis: pathogenic effectors and autoimmune targets |
| Q38747640 | PAD4: pathophysiology, current therapeutics and future perspective in rheumatoid arthritis |
| Q97521521 | Peptidylarginine Deiminase 4 Promotes the Renal Infiltration of Neutrophils and Exacerbates the TLR7 Agonist-Induced Lupus Mice |
| Q47971862 | Peptidylarginine deiminase 2 is required for tumor necrosis factor alpha-induced citrullination and arthritis, but not neutrophil extracellular trap formation |
| Q49319636 | Perspective on Protein Arginine Deiminase Activity-Bicarbonate Is a pH-Independent Regulator of Citrullination |
| Q38995539 | Protein arginine deiminase 4 inhibition is sufficient for the amelioration of collagen-induced arthritis |
| Q93048356 | Reduced Anti-Histone Antibodies and Increased Risk of Rheumatoid Arthritis Associated with a Single Nucleotide Polymorphism in PADI4 in North Americans |
| Q90589903 | Therapeutic ACPA inhibits NET formation: a potential therapy for neutrophil-mediated inflammatory diseases |
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