Ethnogenetic heterogeneity of rheumatoid arthritis-implications for pathogenesis

scientific article published on 16 March 2010

Ethnogenetic heterogeneity of rheumatoid arthritis-implications for pathogenesis is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1038/NRRHEUM.2010.23
P8608Fatcat IDrelease_mvwekoi3z5axjeizauoalcoaay
P698PubMed publication ID20234359

P2093author name stringAkari Suzuki
Kazuhiko Yamamoto
Ryo Yamada
Yuta Kochi
P2860cites workCloning and characterization of a lymphoid-specific, inducible human protein tyrosine phosphatase, LypQ22009057
Molecular characterization of peptidylarginine deiminase in HL-60 cells induced by retinoic acid and 1alpha,25-dihydroxyvitamin D(3)Q22010390
Cutting edge: the PTPN22 allelic variant associated with autoimmunity impairs B cell signalingQ24318432
A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunitiesQ24537702
Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4Q24538382
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controlsQ24550675
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variantsQ24646663
TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide studyQ24657292
Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritisQ28183279
SPAP2, an Ig family receptor containing both ITIMs and ITAMsQ28202935
A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritisQ28267921
Association between PADI4 and rheumatoid arthritis: a replication studyQ28275244
Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variantQ28280659
Fc receptor-like moleculesQ28281703
Differential association of HLA-DRB1 alleles in Japanese patients with early rheumatoid arthritis in relationship to autoantibodies to cyclic citrullinated peptide.Q51751400
Increased susceptibility to rheumatoid arthritis in Koreans heterozygous for HLA-DRB1*0405 and *0901.Q54694309
Pathogen-Driven Selection and Worldwide HLA Class I DiversityQ57008406
Association of Anti–Cyclic citrullinated peptide antibody levels with PADI4 haplotypes in early rheumatoid arthritis and with shared epitope alleles in very late rheumatoid arthritisQ57330799
Genetic and genomic studies of PADI4 in rheumatoid arthritisQ57667794
Association between HLA class II genes and autoantibodies to cyclic citrullinated peptides (CCPs) influences the severity of rheumatoid arthritisQ58234987
Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in miceQ59069058
The genotypic distribution of shared-epitope DRB1 alleles suggests a recessive mode of inheritance of the rheumatoid arthritis disease-susceptibility geneQ71634730
HLA class 2 genes in Singaporean Chinese rheumatoid arthritisQ72117453
The homozygote of HLA-DRB1*0901, not its heterozygote, is associated with rheumatoid arthritis in JapaneseQ77531372
HLA-DRB1 genes and susceptibility to rheumatoid arthritis in three ethnic groups from MalaysiaQ78662159
Association of autoimmune disease-related gene polymorphisms with chronic graft-versus-host diseaseQ81294363
Association of STAT4 with susceptibility to rheumatoid arthritis and systemic lupus erythematosus in the Japanese populationQ81514411
A functional haplotype of the PADI4 gene associated with increased rheumatoid arthritis susceptibility in KoreansQ82132463
The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritisQ28306666
Evaluating gene x gene and gene x smoking interaction in rheumatoid arthritis using candidate genes in GAW15.Q33332902
Behçet's disease, the Silk Road and HLA-B51: historical and geographical perspectivesQ33750943
PADI4 genotype is not associated with rheumatoid arthritis in a large UK Caucasian populationQ34081898
The epidemiology of rheumatoid arthritisQ34275961
Influence of HLA-DR genes on the production of rheumatoid arthritis-specific autoantibodies to citrullinated fibrinogenQ34463613
Contribution of single nucleotide polymorphisms within FCRL3 and MAP3K7IP2 to the pathogenesis of Graves' disease.Q34480522
Rheumatoid arthritis association with the FCRL3 -169C polymorphism is restricted to PTPN22 1858T-homozygous individuals in a Canadian populationQ34585615
Immunity to citrullinated proteins in rheumatoid arthritisQ34732863
Mixed lymphocyte cultures in rheumatoid arthritisQ35200536
Supportive evidence for a genetic association of the FCRL3 promoter polymorphism with rheumatoid arthritisQ35637152
A review of the MHC genetics of rheumatoid arthritis.Q35642056
Gene-gene and gene-environment interactions involving HLA-DRB1, PTPN22, and smoking in two subsets of rheumatoid arthritisQ35752661
Rheumatoid arthritis in American Indians and Alaska Natives: a review of the literatureQ36031009
Association of STAT4 with rheumatoid arthritis in the Korean populationQ36054562
Epidemiology of adult rheumatoid arthritisQ36095154
PTPN22: setting thresholds for autoimmunityQ36491114
STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosusQ37070948
Protein tyrosine phosphatases in autoimmunity.Q37096069
Two independent alleles at 6q23 associated with risk of rheumatoid arthritisQ37120830
REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritisQ37248628
Recent progress in rheumatoid arthritis genetics: one step towards improved patient careQ37443734
FCRL3, an autoimmune susceptibility gene, has inhibitory potential on B-cell receptor-mediated signaling.Q39785312
Regulation of B cell tolerance by the lupus susceptibility gene Ly108.Q40267209
Epidemiological and clinical aspects relating to the variability of rheumatoid arthritisQ41631359
Analysis of single-nucleotide polymorphisms in Japanese rheumatoid arthritis patients shows additional susceptibility markers besides the classic shared epitope susceptibility sequencesQ42617568
Interaction between smoking, the shared epitope, and anti-cyclic citrullinated peptide: a mixed picture in three large North American rheumatoid arthritis cohortsQ42621920
The association of a nonsynonymous single-nucleotide polymorphism in TNFAIP3 with systemic lupus erythematosus and rheumatoid arthritis in the Japanese populationQ42647387
New classification of HLA-DRB1 alleles supports the shared epitope hypothesis of rheumatoid arthritis susceptibilityQ42653008
Association of HLA-DR3 with anti-cyclic citrullinated peptide antibody-negative rheumatoid arthritisQ42669706
Reshaping the shared epitope hypothesis: HLA-associated risk for rheumatoid arthritis is encoded by amino acid substitutions at positions 67-74 of the HLA-DRB1 molecule.Q42674301
Regulation of anti-cyclic citrullinated peptide antibodies in rheumatoid arthritis: contrasting effects of HLA-DR3 and the shared epitope allelesQ42674479
A new model for an etiology of rheumatoid arthritis: smoking may trigger HLA-DR (shared epitope)-restricted immune reactions to autoantigens modified by citrullinationQ42676934
Genetic association of Fc receptor-like 3 polymorphisms with autoimmune pancreatitis in Japanese patientsQ42836171
HLA-DRB1 alleles encoding an aspartic acid at position 70 protect against development of rheumatoid arthritisQ43541170
Ethnic differences in allele frequency of autoimmune-disease-associated SNPs.Q44144728
PTPN22 allele polymorphisms in 15 Chinese populationsQ46221122
Smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cellsQ46643896
The relationship between HLA-DRB1 alleles and disease subsets of rheumatoid arthritis in Japanese.Q50944667
FcRL3 gene promoter variant is associated with peripheral arthritis in Crohn's disease.Q51655067
A functional haplotype of PADI4 gene in rheumatoid arthritis: positive correlation in a French population.Q51744230
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectrheumatoid arthritisQ187255
pathogenesisQ372016
heterogeneityQ928498
P304page(s)290-295
P577publication date2010-03-16
P1433published inNature Reviews RheumatologyQ2107227
P1476titleEthnogenetic heterogeneity of rheumatoid arthritis-implications for pathogenesis
P478volume6

Reverse relations

cites work (P2860)
Q36028278A functional variant in FCRL3 is associated with higher Fc receptor-like 3 expression on T cell subsets and rheumatoid arthritis disease activity.
Q36477515A longitudinal genome-wide association study of anti-tumor necrosis factor response among Japanese patients with rheumatoid arthritis
Q34144942A transient peak of infections during onset of rheumatoid arthritis: a 10-year prospective cohort study
Q35840749Aberrant splicing of the hRasGRP4 transcript and decreased levels of this signaling protein in the peripheral blood mononuclear cells in a subset of patients with rheumatoid arthritis
Q38209903Association of miR-146a polymorphisms with systemic lupus erythematosus: a meta-analysis
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Q38271810Autoimmune thyroid disease and rheumatoid arthritis: relationship and the role of genetics
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Q94959443CD36 gene polymorphism -31118 G > A (rs1761667) is associated with overweight and obesity but not with fat preferences in Mexican children
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Q42244593rs2841277 (PLD4) is associated with susceptibility and rs4672495 is associated with disease activity in rheumatoid arthritis.

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