PTPN22 1858C>T polymorphism distribution in Europe and association with rheumatoid arthritis: case-control study and meta-analysis

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PTPN22 1858C>T polymorphism distribution in Europe and association with rheumatoid arthritis: case-control study and meta-analysis is …
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scholarly articleQ13442814
meta-analysisQ815382

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P819ADS bibcode2011PLoSO...624292T
P356DOI10.1371/JOURNAL.PONE.0024292
P932PMC publication ID3174938
P698PubMed publication ID21949702
P5875ResearchGate publication ID51665627

P50authorGianfranco FerraccioliQ41067658
Valerio NapolioniQ43235166
Elisa GremeseQ50166371
Alice MannocciQ55543098
Barbara TolussoQ56444226
Stefano AliverniniQ57080600
Silvia CanestriQ58328493
Silvia Laura BoselloQ114314203
Michele Ciro TotaroQ114314215
P2093author name stringFrancesca Faustini
P2860cites workReplication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4Q24538382
Moors and Saracens in Europe: estimating the medieval North African male legacy in southern EuropeQ24599308
Rheumatoid arthritis seropositive for the rheumatoid factor is linked to the protein tyrosine phosphatase nonreceptor 22-620W alleleQ24812738
The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritisQ27860872
Differential association of the PTPN22 coding variant with autoimmune diseases in a Dutch populationQ28248685
A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetesQ28248848
Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variantQ28280659
Association of a functional single-nucleotide polymorphism of PTPN22, encoding lymphoid protein phosphatase, with rheumatoid arthritis and systemic lupus erythematosusQ28301821
Association of R602W in a protein tyrosine phosphatase gene with a high risk of rheumatoid arthritis in a British population: evidence for an early onset/disease severity effectQ28301839
Characterizing the quantitative genetic contribution to rheumatoid arthritis using data from twinsQ31460983
Investigation of potential non-HLA rheumatoid arthritis susceptibility loci in a European cohort increases the evidence for nine markersQ34125266
PTPN22 polymorphism and anti-cyclic citrullinated peptide antibodies in combination strongly predicts future onset of rheumatoid arthritis and has a specificity of 100% for the diseaseQ34896568
Association of PTPN22 1858 single-nucleotide polymorphism with rheumatoid arthritis in a German cohort: higher frequency of the risk allele in male compared to female patientsQ34897145
Associations between the PTPN22 1858C->T polymorphism and radiographic joint destruction in patients with rheumatoid arthritis: results from a 10-year longitudinal studyQ36171863
The PTPN22 1858C/T polymorphism is associated with anti-cyclic citrullinated peptide antibody-positive early rheumatoid arthritis in northern SwedenQ36392280
PTPN22: setting thresholds for autoimmunityQ36491114
Association of common polymorphisms in known susceptibility genes with rheumatoid arthritis in a Slovak population using osteoarthritis patients as controlsQ37270770
Rheumatoid arthritis: a view of the current genetic landscapeQ37315484
Ethnogenetic heterogeneity of rheumatoid arthritis-implications for pathogenesisQ37710382
The R620W polymorphism of the protein tyrosine phosphatase 22 gene in autoimmune thyroid diseases and rheumatoid arthritis in the Tunisian populationQ38936485
Functional polymorphisms of PTPN22 and FcgR genes in Tunisian patients with rheumatoid arthritis.Q39448372
Reevaluation of the interaction between HLA-DRB1 shared epitope alleles, PTPN22, and smoking in determining susceptibility to autoantibody-positive and autoantibody-negative rheumatoid arthritis in a large UK Caucasian populationQ42632057
Effects of PTPN22 C1858T polymorphism on susceptibility and clinical characteristics of British Caucasian rheumatoid arthritis patients.Q42680902
PTPN22 1858C>T polymorphism is strongly associated with rheumatoid arthritis but not with a response to methotrexate therapyQ42871416
Discovery of a novel submicromolar inhibitor of the lymphoid specific tyrosine phosphatase.Q43106114
Finnish case-control and family studies support PTPN22 R620W polymorphism as a risk factor in rheumatoid arthritis, but suggest only minimal or no effect in juvenile idiopathic arthritisQ44449408
Genetic variation in PTPN22 corresponds to altered function of T and B lymphocytesQ44932416
Protein tyrosine phosphatase gene C1858T allele confers risk for rheumatoid arthritis in Hungarian subjectsQ45129416
No association of PTPN22 gene polymorphism with rheumatoid arthritis in TurkeyQ46055652
Association analysis of the 1858C>T polymorphism in the PTPN22 gene in juvenile idiopathic arthritis and other autoimmune diseasesQ46368513
The PTPN22 620W allele confers susceptibility to systemic sclerosis: findings of a large case-control study of European Caucasians and a meta-analysis.Q46521556
Association between the PTPN22 gene and rheumatoid arthritis and juvenile idiopathic arthritis in a UK population: further support that PTPN22 is an autoimmunity geneQ46525978
Association of the PTPN22 C1858T single-nucleotide polymorphism with rheumatoid arthritis phenotypes in an inception cohort.Q46689842
Auto-antibodies, HLA and PTPN22: susceptibility markers for rheumatoid arthritisQ46835340
Association between protein tyrosine phosphatase 22 variant R620W in conjunction with the HLA-DRB1 shared epitope and humoral autoimmunity to an immunodominant epitope of cartilage-specific type II collagen in early rheumatoid arthritisQ46872978
Genomic DNA pooling for whole-genome association scans in complex disease: empirical demonstration of efficacy in rheumatoid arthritisQ54330502
2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiativeQ56506042
The PTPN22 R263Q polymorphism is a risk factor for rheumatoid arthritis in Caucasian case-control samplesQ57154867
The 620W allele is the PTPN22 genetic variant conferring susceptibility to RA in a Dutch populationQ58234945
Association of PTPN22 single nucleotide polymorphism with rheumatoid arthritis but not with allergic asthmaQ59697424
The FCRL3 -169T>C polymorphism is associated with rheumatoid arthritis and shows suggestive evidence of involvement with juvenile idiopathic arthritis in a Scandinavian panel of autoimmune diseasesQ80161055
The PTPN22 promoter polymorphism -1123G>C association cannot be distinguished from the 1858C>T association in a Norwegian rheumatoid arthritis materialQ80697518
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectrheumatoid arthritisQ187255
meta-analysisQ815382
P304page(s)e24292
P577publication date2011-09-16
P1433published inPLOS OneQ564954
P1476titlePTPN22 1858C>T polymorphism distribution in Europe and association with rheumatoid arthritis: case-control study and meta-analysis
P478volume6

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cites work (P2860)
Q34447782Assessment of protein tyrosine phosphatases number 22 polymorphism prevalence among rheumatoid arthritis patients: A study on Iranian patients
Q36335826Association between PTPN22 C1858T polymorphism and alopecia areata risk
Q46840442Association of PTPN22 1858C→T polymorphism, HLA-DRB1 shared epitope and autoantibodies with rheumatoid arthritis.
Q43654959Association of PTPN22 rs2476601 and EGFR rs17337023 Gene polymorphisms and rheumatoid arthritis in Zahedan, Southeast Iran.
Q51046617Association of STAT4 rs7574865 and PTPN22 rs2476601 polymorphisms with rheumatoid arthritis and non-systemically reacting antibodies in Egyptian patients.
Q28482717Biochemical and functional studies of lymphoid-specific tyrosine phosphatase (Lyp) variants S201F and R266W
Q37590849General and Specific Genetic Polymorphism of Cytokines-Related Gene in AITD.
Q36907619Investigation of Caucasian rheumatoid arthritis susceptibility loci in African patients with the same disease
Q36933138Macrophage migration inhibitory factor (MIF): genetic evidence for participation in early onset and early stage rheumatoid arthritis.
Q34516914Meta-analysis of 125 rheumatoid arthritis-related single nucleotide polymorphisms studied in the past two decades
Q40111723Meta-analysis reveals PTPN22 1858C/T polymorphism confers susceptibility to rheumatoid arthritis in Caucasian but not in Asian population
Q36058554Overexpression of the autoimmunity-associated phosphatase PTPN22 promotes survival of antigen-stimulated CLL cells by selectively activating AKT.
Q34946314PTPN22 association in systemic lupus erythematosus (SLE) with respect to individual ancestry and clinical sub-phenotypes
Q41848532PTPN22 splice forms: a new role in rheumatoid arthritis.
Q34438363Potential of ayurgenomics approach in complex trait research: leads from a pilot study on rheumatoid arthritis
Q60948114TNFAIP3 F127C Coding Variation in Greek Primary Sjogren's Syndrome Patients
Q90207982The Contribution of PTPN22 to Rheumatic Disease
Q55056993The PTPN22 C1858T polymorphism and rheumatoid arthritis: a meta-analysis.
Q43646920The impact of CTLA4 and PTPN22 genes polymorphisms on long-term renal allograft function and transplant outcomes
Q37054990The role of PTPN22 C1858T gene polymorphism in diabetes mellitus type 1: first evaluation in Greek children and adolescents
Q44532167Variants in PTPN22 and SMOC2 genes and the risk of thyroid disease in the Jordanian Arab population

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