Genomic DNA pooling for whole-genome association scans in complex disease: empirical demonstration of efficacy in rheumatoid arthritis (scientific article published on 7 December 2006)

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The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

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A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis

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The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis

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Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies

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PTPN22 genetic variation: evidence for multiple variants associated with rheumatoid arthritis

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Using linkage genome scans to improve power of association in genome scans

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Association testing by DNA pooling: an effective initial screen

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Whole genome association study of rheumatoid arthritis using 27 039 microsatellites

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A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region

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Association between a variation inLRCH1 and knee osteoarthritis: A genome-wide single-nucleotide polymorphism association study using DNA pooling

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HLA class III haplotypes in multicase rheumatoid arthritis families

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Genetics of rheumatoid arthritis (RA): two separate regions in the major histocompatibility complex contribute to susceptibility to RA

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The telomeric part of the HLA region predisposes to rheumatoid arthritis independently of the class II loci

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A high-resolution survey of deletion polymorphism in the human genome

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P433

issue

P921

main subject

rheumatoid arthritis

Q187255

whole genome sequencing

Q2068526

P304

page(s)

57-68

P577

publication date

2006-12-07

P1433

published in

Genes and Immunity

Q15745246

P1476

title

Genomic DNA pooling for whole-genome association scans in complex disease: empirical demonstration of efficacy in rheumatoid arthritis.

P478

volume

Reverse relations

cites work (P2860)

Q33289150	A DArT platform for quantitative bulked segregant analysis
Q48077040	A Pooling Genome-Wide Association Study Combining a Pathway Analysis for Typical Sporadic Parkinson's Disease in the Han Population of Chinese Mainland
Q33794452	A genome-wide association study identifies multiple loci associated with mathematics ability and disability
Q24655759	A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder
Q28943536	A genome-wide association study in 574 schizophrenia trios using DNA pooling
Q30475974	A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations
Q33314661	A hierarchical and modular approach to the discovery of robust associations in genome-wide association studies from pooled DNA samples
Q30955298	A pooling-based genome-wide analysis identifies new potential candidate genes for atopy in the European Community Respiratory Health Survey (ECRHS).
Q37018101	A review of current approaches to identifying human genes involved in myopia.
Q33289927	Applicability of DNA pools on 500 K SNP microarrays for cost-effective initial screens in genomewide association studies
Q36709524	Assignment of SNP allelic configuration in polyploids using competitive allele-specific PCR: application to citrus triploid progeny
Q40222230	Association of PTPN22 Single Nucleotide Polymorphisms with Celiac Disease
Q46923561	Association of genetic variants in GABRA3 gene and thyrotoxic hypokalaemic periodic paralysis in Thai population
Q35130219	Candidate genes for non-diabetic ESRD in African Americans: a genome-wide association study using pooled DNA.
Q60924390	Comparative study for haplotype block partitioning methods - Evidence from chromosome 6 of the North American Rheumatoid Arthritis Consortium (NARAC) dataset
Q34038213	Computational method for estimating DNA copy numbers in normal samples, cancer cell lines, and solid tumors using array comparative genomic hybridization
Q39606833	FUT2: filling the gap between genes and environment in Behçet's disease?
Q35694393	Genetic Variants Underlying Risk of Intracranial Aneurysms: Insights from a GWAS in Portugal.
Q37032887	Genetic developments in autoimmune thyroid disease: an evolutionary process
Q35661517	Genetic factors of autoimmune thyroid diseases in Japanese
Q80684055	Genetics of chronic obstructive pulmonary disease
Q28943498	Genome-wide association scan identifies a prostaglandin-endoperoxide synthase 2 variant involved in risk of knee osteoarthritis
Q36593761	Highly cost-efficient genome-wide association studies using DNA pools and dense SNP arrays
Q89965572	Identification of 67 Pleiotropic Genes Associated With Seven Autoimmune/Autoinflammatory Diseases Using Multivariate Statistical Analysis
Q36783894	Identification of SPOCK2 as a susceptibility gene for bronchopulmonary dysplasia
Q28943483	Identification of ZNF313/RNF114 as a novel psoriasis susceptibility gene
Q35105700	Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease
Q57249724	Identification of susceptibility genes for complex diseases using pooling-based genome-wide association scans
Q47555364	Identifying and exploiting trait-relevant tissues with multiple functional annotations in genome-wide association studies
Q42035322	Methodological Issues in Multistage Genome-wide Association Studies
Q30478361	Modifiers of hearing impairment in humans and mice
Q36024006	Multicentric Genome-Wide Association Study for Primary Spontaneous Pneumothorax
Q41859735	Multimarker analysis and imputation of multiple platform pooling-based genome-wide association studies
Q48219517	NLRP1, PTPN22 and PADI4 gene polymorphisms and rheumatoid arthritis in ACPA-positive Singaporean Chinese
Q34031304	PTPN22 1858C>T polymorphism distribution in Europe and association with rheumatoid arthritis: case-control study and meta-analysis
Q40265320	PTPN22 Single-Nucleotide Polymorphisms in Iranian Patients with Type 1 Diabetes Mellitus
Q52615322	PheWAS and Beyond: The Landscape of Associations with Medical Diagnoses and Clinical Measures across 38,662 Individuals from Geisinger.
Q33904168	Phenotypic variability of patients homozygous for the GJB2 mutation 35delG cannot be explained by the influence of one major modifier gene
Q33970796	Pooling-based genome-wide association study implicates gamma-glutamyltransferase 1 (GGT1) gene in pancreatic carcinogenesis
Q46147942	Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis.
Q82436903	Susceptibility influence of a PTPN22 haplotype with thyroid autoimmunity in Koreans
Q37461017	Systems biology and heart failure: concepts, methods, and potential research applications
Q33727899	The PTPN22 locus and rheumatoid arthritis: no evidence for an effect on risk independent of Arg620Trp
Q40202718	The Potential Mutation of GAK Gene in the Typical Sporadic Parkinson's Disease from the Han Population of Chinese Mainland.
Q33735365	Utility of the pooling approach as applied to whole genome association scans with high-density Affymetrix microarrays
Q33517973	Validation of pooled genotyping on the Affymetrix 500 k and SNP6.0 genotyping platforms using the polynomial-based probe-specific correction