Analysis of the Trypanosoma brucei EATRO 164 Bloodstream Guide RNA Transcriptome

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Analysis of the Trypanosoma brucei EATRO 164 Bloodstream Guide RNA Transcriptome is …
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scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PNTD.0004793
P932PMC publication ID4939953
P698PubMed publication ID27399202

P50authorYanni SunQ63368381
P2093author name stringLaura E Kirby
David Judah
Donna Koslowsky
Scooter Nowak
P2860cites workMost mammalian mRNAs are conserved targets of microRNAsQ24655061
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform ExtractionQ25938986
Mitochondrial RNA editing in trypanosomes: small RNAs in controlQ27027472
A model for RNA editing in kinetoplastid mitochondria: "guide" RNA molecules transcribed from maxicircle DNA provide the edited informationQ28255689
Unassigned MURF1 of kinetoplastids codes for NADH dehydrogenase subunit 2Q33373515
Developments in the differentiation of Trypanosoma bruceiQ33611156
Bottlenecks and the maintenance of minor genotypes during the life cycle of Trypanosoma brucei.Q33649716
Native mitochondrial RNA-binding complexes in kinetoplastid RNA editing differ in guide RNA compositionQ33967980
Major transcript of the frameshifted coxII gene from trypanosome mitochondria contains four nucleotides that are not encoded in the DNA.Q34048640
Pentatricopeptide repeat proteins stimulate mRNA adenylation/uridylation to activate mitochondrial translation in trypanosomesQ34774754
Editing of Trypanosoma brucei maxicircle CR5 mRNA generates variable carboxy terminal predicted protein sequencesQ34823171
The MURF3 gene of T. brucei contains multiple domains of extensive editing and is homologous to a subunit of NADH dehydrogenaseQ34933043
Uridine insertion/deletion editing in trypanosomes: a playground for RNA-guided information transferQ35158070
Transcript-specific developmental regulation of polyadenylation in Trypanosoma brucei mitochondriaQ52231406
Developmental regulation of trypanosome mitochondrial gene expression.Q52257960
Developmentally regulated addition of nucleotides within apocytochrome b transcripts in Trypanosoma bruceiQ68985718
Structural analysis of variant and invariant genes in trypanosomesQ71387406
Genomic organization of Trypanosoma brucei kinetoplast DNA minicirclesQ78752781
Alternative editing of cytochrome c oxidase III mRNA in trypanosome mitochondria generates protein diversityQ35191171
Enigmatic presence of mitochondrial complex I in Trypanosoma brucei bloodstream formsQ35739001
In vivo analysis of trypanosome mitochondrial RNA function by artificial site-specific RNA endonuclease-mediated knockdown.Q36072312
Modification of Trypanosoma brucei mitochondrial rRNA by posttranscriptional 3' polyuridine tail formationQ36742522
Developmental aspects of uridine addition within mitochondrial transcripts of Trypanosoma bruceiQ36785424
Guide RNAs for transcripts with developmentally regulated RNA editing are present in both life cycle stages of Trypanosoma bruceiQ36814583
Extensive editing of CR2 maxicircle transcripts of Trypanosoma brucei predicts a protein with homology to a subunit of NADH dehydrogenaseQ36825292
Diverse patterns of expression of the cytochrome c oxidase subunit I gene and unassigned reading frames 4 and 5 during the life cycle of Trypanosoma bruceiQ36951326
Multiple-strain infections of Trypanosoma brucei across AfricaQ36971186
Kinetoplast DNA-encoded ribosomal protein S12: a possible functional link between mitochondrial RNA editing and translation in Trypanosoma bruceiQ37534381
The insect-phase gRNA transcriptome in Trypanosoma bruceiQ37574200
Differential expression of mitochondrial genes between life cycle stages of Trypanosoma bruceiQ37688632
A high level of mixed Trypanosoma brucei infections in tsetse flies detected by three hypervariable minisatellitesQ38886449
An intragenic guide RNA location suggests a complex mechanism for mitochondrial gene expression in Trypanosoma bruceiQ39601561
The sequence of the gene for cytochromecoxidase subunit I, a frameshift containing gene for cytochromecoxidase subunit II and seven unassigned reading frames inTrypanosoma bruceimitochondrial maxi-cirle DNAQ40461861
Apocytochrome b and other mitochondrial DNA sequences are differentially expressed during the life cycle of Trypanosoma brucei.Q40470810
The major transcripts of the kinetoplast DNA of Trypanosoma brucei are very small ribosomal RNAs.Q40489878
Maxicircle CR1 transcripts of Trypanosoma brucei are edited and developmentally regulated and encode a putative iron-sulfur protein homologous to an NADH dehydrogenase subunitQ40654645
Developmental regulation of mitochondrial biogenesis in Trypanosoma bruceiQ40686731
The RNA editing process in Trypanosoma bruceiQ40780666
Insertional and deletional RNA editing in trypanosome mitochondria.Q41710152
Trypanosoma brucei mitochondrial CR4 gene encodes an extensively edited mRNA with completely edited sequence only in bloodstream formsQ42600621
Extensive editing of both processed and preprocessed maxicircle CR6 transcripts in Trypanosoma bruceiQ42617615
An extensively edited mitochondrial transcript in kinetoplastids encodes a protein homologous to ATPase subunit 6.Q42630911
Extensive editing of the cytochrome c oxidase III transcript in Trypanosoma bruceiQ43573848
The mitochondrion in bloodstream forms of Trypanosoma brucei is energized by the electrogenic pumping of protons catalysed by the F1F0-ATPaseQ43651782
Complex I (NADH:ubiquinone oxidoreductase) is active in but non-essential for procyclic Trypanosoma brucei.Q43979464
Procyclic Trypanosoma brucei do not use Krebs cycle activity for energy generationQ44299979
Differential expression of glycosomal and mitochondrial proteins in the two major life-cycle stages of Trypanosoma bruceiQ46170634
Mitochondrial translation is essential in bloodstream forms of Trypanosoma bruceiQ46504276
The IsTaR 1 serodeme of Trypanosoma brucei: development of a new serodeme.Q46697549
Multiple guide RNAs for identical editing of Trypanosoma brucei apocytochrome b mRNA have an unusual minicircle location and are developmentally regulatedQ48084875
Identification of mitochondrial genes in Trypanosoma brucei and homology to cytochrome c oxidase II in two different reading framesQ48379439
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectTrypanosoma bruceiQ33244
P304page(s)e0004793
P577publication date2016-07-11
P1433published inPLoS Neglected Tropical DiseasesQ3359737
P1476titleAnalysis of the Trypanosoma brucei EATRO 164 Bloodstream Guide RNA Transcriptome
P478volume10

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cites work (P2860)
Q91996639Cell-line specific RNA editing patterns in Trypanosoma brucei suggest a unique mechanism to generate protein variation in a system intolerant to genetic mutations
Q57210417High throughput sequencing revolution reveals conserved fundamentals of U-indel editing
Q64230074Intrinsic and regulated properties of minimally edited trypanosome mRNAs
Q90459807Lexis and Grammar of Mitochondrial RNA Processing in Trypanosomes
Q46844300Mitochondrial dual-coding genes in Trypanosoma brucei
Q92026081Separating the Wheat from the Chaff: RNA Editing and Selection of Translatable mRNA in Trypanosome Mitochondria
Q59335706The 27 kDa Trypanosoma brucei Pentatricopeptide Repeat Protein is a G-tract Specific RNA Binding Protein
Q57751146Transcription initiation defines kinetoplast RNA boundaries
Q46245200Trypanosomatid mitochondrial RNA editing: dramatically complex transcript repertoires revealed with a dedicated mapping tool.
Q38768933Trypanosome RNA Editing Mediator Complex proteins have distinct functions in gRNA utilization

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