New insights on endocannabinoid transmission in psychomotor disorders

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New insights on endocannabinoid transmission in psychomotor disorders is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.PNPBP.2012.04.002
P932PMC publication ID3389227
P698PubMed publication ID22521335

P2093author name stringAndrea Giuffrida
Alexandre Seillier
P2860cites workIdentification and cloning of three novel human G protein-coupled receptor genes GPR52, PsiGPR53 and GPR55: GPR55 is extensively expressed in human brainQ22001491
Atypical responsiveness of the orphan receptor GPR55 to cannabinoid ligandsQ24311776
N-acyl-dopamines: novel synthetic CB(1) cannabinoid-receptor ligands and inhibitors of anandamide inactivation with cannabimimetic activity in vitro and in vivoQ24532188
Brain monoglyceride lipase participating in endocannabinoid inactivationQ24533828
An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptorsQ24534526
Endocannabinoid-mediated long-term plasticity requires cAMP/PKA signaling and RIM1alphaQ24564778
Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effectsQ24569799
The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptorsQ24617322
2-arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptorQ24620096
Receptors for acylethanolamides-GPR55 and GPR119Q24647538
Lipid G protein-coupled receptor ligand identification using beta-arrestin PathHunter assayQ24654730
The orphan receptor GPR55 is a novel cannabinoid receptorQ24670137
Anandamide and vanilloid TRPV1 receptorsQ24672354
The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effectsQ24681369
Cannabinoid activation of PPAR alpha; a novel neuroprotective mechanismQ24681426
Novel cannabinoid receptorsQ24681482
Evidence against the presence of an anandamide transporterQ24683153
Endocannabinoid signalling in the blood of patients with schizophreniaQ24800061
Role of endogenous cannabinoids in synaptic signalingQ28185075
Increased cannabinoid CB1 receptor binding and activation of GTP-binding proteins in the basal ganglia of patients with Parkinson's syndrome and of MPTP-treated marmosetsQ28203208
CB1 cannabinoid receptors and on-demand defense against excitotoxicityQ28207143
Retrograde inhibition of presynaptic calcium influx by endogenous cannabinoids at excitatory synapses onto Purkinje cellsQ28212245
Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptorQ28218654
Cannabinoids and psychosisQ28241328
mu-Opioid receptor forms a functional heterodimer with cannabinoid CB1 receptor: electrophysiological and FRET assay analysis.Q39917016
Multiple pathways involved in the biosynthesis of anandamideQ40106992
Identification of a novel endocannabinoid-hydrolyzing enzyme expressed by microglial cellsQ40158906
Stimulation of endocannabinoid formation in brain slice cultures through activation of group I metabotropic glutamate receptors.Q46624652
Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of clozapine, but not haloperidolQ46649583
Endocannabinoids activate transient receptor potential vanilloid 1 receptors to reduce hyperdopaminergia-related hyperactivity: therapeutic implicationsQ46731448
A preliminary investigation into the effects of antipsychotics on sub-chronic phencyclidine-induced deficits in attentional set-shifting in female ratsQ46747113
Immunolocalization of CB1 receptor in rat striatal neurons: a confocal microscopy study.Q47242856
Cannabinoid receptors differentially modulate potassium A and D currents in hippocampal neurons in cultureQ48088888
Role of the cyclic-AMP/PKA cascade and of P/Q-type Ca++ channels in endocannabinoid-mediated long-term depression in the nucleus accumbens.Q48118951
Subcellular arrangement of molecules for 2-arachidonoyl-glycerol-mediated retrograde signaling and its physiological contribution to synaptic modulation in the striatum.Q48217036
Cannabinoids and neuroprotection in global and focal cerebral ischemia and in neuronal culturesQ48246173
Cannabinoid CB1 receptor antagonism prevents neurochemical and behavioural deficits induced by chronic phencyclidineQ48286778
Evaluation of the neuroprotective effect of cannabinoids in a rat model of Parkinson's disease: importance of antioxidant and cannabinoid receptor-independent propertiesQ48324018
Atypical antipsychotics attenuate a sub-chronic PCP-induced cognitive deficit in the novel object recognition task in the rat.Q48390432
Anandamide administration alone and after inhibition of fatty acid amide hydrolase (FAAH) increases dopamine levels in the nucleus accumbens shell in ratsQ48485540
Increased cannabinoid receptor density in the posterior cingulate cortex in schizophreniaQ48532654
Concurrent stimulation of cannabinoid CB1 and dopamine D2 receptors augments cAMP accumulation in striatal neurons: evidence for a Gs linkage to the CB1 receptor.Q48658239
Anandamide levels in cerebrospinal fluid of first-episode schizophrenic patients: impact of cannabis use.Q51902545
Evolutionary origins of the endocannabinoid systemQ56899189
A role for vanilloid receptor 1 (TRPV1) and endocannabinnoid signalling in the regulation of spontaneous and L-DOPA induced locomotion in normal and reserpine-treated ratsQ60690596
Cannabinoid receptor 1 gene (CNR1) and susceptibility to a quantitative phenotype for hebephrenic schizophreniaQ61413499
Chronic L-DOPA treatment increases striatal cannabinoid CB1 receptor mRNA expression in 6-hydroxydopamine-lesioned ratsQ64814751
Towards a cannabinoid hypothesis of schizophrenia: cognitive impairments due to dysregulation of the endogenous cannabinoid system.Q64996366
Elevated endogenous cannabinoids in schizophreniaQ73029596
Are cannabinoids endogenous ligands for the VR1 capsaicin receptor?Q73423096
Reversal of dopamine D(2) receptor responses by an anandamide transport inhibitorQ73704501
Blockade of cannabinoid type 1 receptors augments the antiparkinsonian action of levodopa without affecting dyskinesias in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated rhesus monkeysQ80609691
Is the highest density of CB1 receptors in paranoid schizophrenia a correlate of endocannabinoid system functioning?Q84611635
Chemically distinct ligands promote differential CB1 cannabinoid receptor-Gi protein interactions.Q40449973
Anandamide inhibits nuclear factor-kappaB activation through a cannabinoid receptor-independent pathway.Q40677598
The activity of anandamide at vanilloid VR1 receptors requires facilitated transport across the cell membrane and is limited by intracellular metabolismQ40817229
The behavioral and neurochemical effects of phencyclidine in humans and animals: some implications for modeling psychosisQ41147529
Cell biology. Anatomy of prostaglandin signalsQ41541063
Dopamine activation of endogenous cannabinoid signaling in dorsal striatumQ41646203
Cannabinoids decrease the K(+) M-current in hippocampal CA1 neurons.Q41713139
Endocannabinoid biosynthesis proceeding through glycerophospho-N-acyl ethanolamine and a role for alpha/beta-hydrolase 4 in this pathwayQ41791622
A cytochrome P450-derived epoxygenated metabolite of anandamide is a potent cannabinoid receptor 2-selective agonistQ42017075
The endocannabinoid 2-arachidonoylglycerol is responsible for the slow self-inhibition in neocortical interneuronsQ42110966
Subchronic and chronic PCP treatment produces temporally distinct deficits in attentional set shifting and prepulse inhibition in ratsQ42166759
Immunolocalization of peroxisome proliferator-activated receptors and retinoid X receptors in the adult rat CNS.Q42454049
Subcellular localization of type 1 cannabinoid receptors in the rat basal gangliaQ42486484
Unilateral 6-hydroxydopamine lesions of nigrostriatal dopaminergic neurons increased CB1 receptor mRNA levels in the caudate-putamenQ42487505
Genetic deletion of monoacylglycerol lipase alters endocannabinoid-mediated retrograde synaptic depression in the cerebellumQ42494226
Endocannabinoid-mediated rescue of striatal LTD and motor deficits in Parkinson's disease modelsQ42508054
Expression and function of CB1 receptor in the rat striatum: localization and effects on D1 and D2 dopamine receptor-mediated motor behaviors.Q42520647
Anandamide inhibits metabolism and physiological actions of 2-arachidonoylglycerol in the striatumQ42523780
Involvement of vanilloid-like receptors in the effects of anandamide on motor behavior and nigrostriatal dopaminergic activity: in vivo and in vitro evidence.Q42624110
The effects of cannabinoid drugs on abnormal involuntary movements in dyskinetic and non-dyskinetic 6-hydroxydopamine lesioned ratsQ42871461
Monoacylglycerol lipase activity is a critical modulator of the tone and integrity of the endocannabinoid systemQ42882543
Regulation of plasticity of glutamate synapses by endocannabinoids and the cyclic-AMP/protein kinase A pathway in midbrain dopamine neuronsQ43055373
Quantification of cerebral cannabinoid receptors subtype 1 (CB1) in healthy subjects and schizophrenia by the novel PET radioligand [11C]OMAR.Q43091758
Individual differences in the effects of cannabinoids on motor activity, dopaminergic activity and DARPP-32 phosphorylation in distinct regions of the brainQ43235028
Cannabinoid self-administration attenuates PCP-induced schizophrenia-like symptoms in adult ratsQ43255656
Microglial CB2 cannabinoid receptors are neuroprotective in Huntington's disease excitotoxicity.Q43266820
Evaluation of NMDA receptor models of schizophrenia: divergences in the behavioral effects of sub-chronic PCP and MK-801.Q43283706
Immunodensity and mRNA expression of A2A adenosine, D2 dopamine, and CB1 cannabinoid receptors in postmortem frontal cortex of subjects with schizophrenia: effect of antipsychotic treatmentQ43299005
Enhanced levels of endogenous cannabinoids in the globus pallidus are associated with a reduction in movement in an animal model of Parkinson's diseaseQ43504648
Studies on [3H]CP-55940 binding in the human central nervous system: regional specific changes in density of cannabinoid-1 receptors associated with schizophrenia and cannabis use.Q43581230
Cannabinoid receptor agonist and antagonist effects on motor function in normal and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP)-treated non-human primates.Q43683165
Unawareness of dyskinesias in Parkinson's and Huntington's diseasesQ43696853
Postsynaptic endocannabinoid release is critical to long-term depression in the striatumQ43971441
The endogenous cannabinoid system controls extinction of aversive memoriesQ44085607
Protective action of the peroxisome proliferator-activated receptor-gamma agonist pioglitazone in a mouse model of Parkinson's disease.Q44086465
Experimental parkinsonism alters endocannabinoid degradation: implications for striatal glutamatergic transmission.Q44102387
Effects of CB1 cannabinoid receptor modulating compounds on the hyperkinesia induced by high-dose levodopa in the reserpine-treated rat model of Parkinson's diseaseQ44285779
Ultrastructural localization of the CB1 cannabinoid receptor in mu-opioid receptor patches of the rat Caudate putamen nucleus.Q44334367
Loss of bidirectional striatal synaptic plasticity in L-DOPA-induced dyskinesiaQ44383212
Presynaptic Facilitation of Glutamatergic Synapses to Dopaminergic Neurons of the Rat Substantia Nigra by Endogenous Stimulation of Vanilloid ReceptorsQ44418969
Neuroanatomical relationship between type 1 cannabinoid receptors and dopaminergic systems in the rat basal gangliaQ44451116
Endogenous interleukin-1 receptor antagonist mediates anti-inflammatory and neuroprotective actions of cannabinoids in neurons and glia.Q44524201
Effects of levodopa on endocannabinoid levels in rat basal ganglia: implications for the treatment of levodopa‐induced dyskinesiasQ44597458
Formation of prostamides from anandamide in FAAH knockout mice analyzed by HPLC with tandem mass spectrometryQ44733045
Selective antagonist [3H]SR141716A binding to cannabinoid CB1 receptors is increased in the anterior cingulate cortex in schizophreniaQ44748286
Cannabinoids enhance subsecond dopamine release in the nucleus accumbens of awake rats.Q44885114
Neurokinin B, neurotensin, and cannabinoid receptor antagonists and Parkinson diseaseQ44931450
Cerebrospinal anandamide levels are elevated in acute schizophrenia and are inversely correlated with psychotic symptomsQ45049153
Inhibition of fatty-acid amide hydrolase and CB1 receptor antagonism differentially affect behavioural responses in normal and PCP-treated rats.Q45927862
Oleoylethanolamide exerts partial and dose-dependent neuroprotection of substantia nigra dopamine neurons.Q46205733
Involvement of the endocannabinoid system in phencyclidine-induced cognitive deficits modelling schizophreniaQ46370479
Involvement of cannabinoid receptors in the regulation of neurotransmitter release in the rodent striatum: a combined immunochemical and pharmacological analysis.Q46384445
Cannabinoids provide neuroprotection against 6-hydroxydopamine toxicity in vivo and in vitro: relevance to Parkinson's diseaseQ46443478
A role for endocannabinoids in the generation of parkinsonism and levodopa-induced dyskinesia in MPTP-lesioned non-human primate models of Parkinson's diseaseQ46491157
Cannabinoids inhibit N- and P/Q-type calcium channels in cultured rat hippocampal neuronsQ28245016
Agonist-directed trafficking of response by endocannabinoids acting at CB2 receptorsQ28265832
Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampusQ28268567
Cannabinoid action depends on phosphorylation of dopamine- and cAMP-regulated phosphoprotein of 32 kDa at the protein kinase A site in striatal projection neuronsQ28272251
Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amidesQ28295481
International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB₁ and CB₂Q28298445
Expression of peroxisome proliferator-activated receptors (PPARs) and retinoic acid receptors (RXRs) in rat cortical neuronsQ28573124
Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid systemQ28590486
Parkinson's disease: mechanisms and modelsQ29547424
The molecular logic of endocannabinoid signallingQ29615356
Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic studyQ29615905
Targeting dopamine D2 and cannabinoid-1 (CB1) receptors in rat nucleus accumbensQ30499463
Animal models of neurological deficits: how relevant is the rat?Q31091605
CB1 cannabinoid receptor inhibits synaptic release of glutamate in rat dorsolateral striatumQ31817073
Clozapine, but not haloperidol, reverses social behavior deficit in mice during withdrawal from chronic phencyclidine treatment.Q31997655
Identification and characterisation of a novel splice variant of the human CB1 receptorQ33210400
Concurrent stimulation of cannabinoid CB1 and dopamine D2 receptors enhances heterodimer formation: a mechanism for receptor cross-talk?Q33211909
The neuropsychopharmacology of phencyclidine: from NMDA receptor hypofunction to the dopamine hypothesis of schizophreniaQ33537860
Minireview: recent developments in the physiology and pathology of the lysophosphatidylinositol-sensitive receptor GPR55.Q33636763
Carrier-mediated transport and enzymatic hydrolysis of the endogenous cannabinoid 2-arachidonylglycerolQ33902321
Reduced cortical cannabinoid 1 receptor messenger RNA and protein expression in schizophreniaQ33932087
The uptake by cells of 2-arachidonoylglycerol, an endogenous agonist of cannabinoid receptorsQ33940288
Endogenous cannabinoids mediate retrograde signalling at hippocampal synapsesQ33940688
Paranoid schizophrenia is characterized by increased CB1 receptor binding in the dorsolateral prefrontal cortexQ34026425
An endogenous cannabinoid (2-AG) is neuroprotective after brain injuryQ34093755
Phencyclidine (PCP): a dangerous drug, but useful in schizophrenia researchQ34147040
Biosynthesis and degradation of the endocannabinoid 2-arachidonoylglycerolQ34165188
A synthetic cannabinoid agonist promotes oligodendrogliogenesis during viral encephalitis in ratsQ34308648
The role of glial cells in Parkinson's diseaseQ34318207
Anandamide transport is independent of fatty-acid amide hydrolase activity and is blocked by the hydrolysis-resistant inhibitor AM1172.Q34320147
Cannabis for dyskinesia in Parkinson disease: a randomized double-blind crossover studyQ34358022
Prevention of Alzheimer's disease pathology by cannabinoids: neuroprotection mediated by blockade of microglial activation.Q34397288
Evidence for novel cannabinoid receptorsQ34415409
An endocannabinoid mechanism for stress-induced analgesia.Q34428429
Relationship of cannabinoid CB1 receptor and cholecystokinin immunoreactivity in monkey dorsolateral prefrontal cortexQ34536072
A second fatty acid amide hydrolase with variable distribution among placental mammalsQ34570802
CB1-independent inhibition of dopamine transporter activity by cannabinoids in mouse dorsal striatumQ34605794
Expression of CB1 cannabinoid receptor in the anterior cingulate cortex in schizophrenia, bipolar disorder, and major depressionQ34609936
Transient receptor potential channels: targeting pain at the sourceQ34912798
Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegenerationQ34983386
Cannabinoids and neuroinflammationQ35046205
Commentary: Functional Neuronal CB2 Cannabinoid Receptors in the CNSQ35107820
Endogenous fatty acid ethanolamides suppress nicotine-induced activation of mesolimbic dopamine neurons through nuclear receptorsQ35202878
Cellular accumulation of anandamide: consensus and controversyQ35217244
Glutamate, dopamine, and schizophrenia: from pathophysiology to treatmentQ35611010
Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammationQ35645037
Functional selectivity in CB(2) cannabinoid receptor signaling and regulation: implications for the therapeutic potential of CB(2) ligands.Q35688511
The cannabinoid agonist WIN55212-2 decreases L-DOPA-induced PKA activation and dyskinetic behavior in 6-OHDA-treated ratsQ35740152
New perspectives in the studies on endocannabinoid and cannabis: cannabinoid receptors and schizophreniaQ35991093
Alterations of endocannabinoid signaling, synaptic plasticity, learning, and memory in monoacylglycerol lipase knock-out miceQ36020820
Differential signalling in human cannabinoid CB1 receptors and their splice variants in autaptic hippocampal neurones.Q36176523
Anti-dyskinetic effects of cannabinoids in a rat model of Parkinson's disease: role of CB(1) and TRPV1 receptors.Q36248857
Cannabinoids and prefrontal cortical function: insights from preclinical studiesQ36436004
Cannabinoid control of motor function at the basal ganglia.Q36441208
The roles of cannabinoid and dopamine receptor systems in neural emotional learning circuits: implications for schizophrenia and addictionQ36478275
Biochemistry and pharmacology of endovanilloidsQ36756199
Cannabinoids and psychosisQ36756388
The endocannabinoid system and neurogenesis in health and disease.Q36778571
Phencyclidine and genetic animal models of schizophrenia developed in relation to the glutamate hypothesisQ36869809
Parkinson's disease: levodopa-induced dyskinesia and signal transduction.Q37086131
Neurochemical changes in the striatum of dyskinetic rats after administration of the cannabinoid agonist WIN55,212-2Q37132571
Endocannabinoid-dependent plasticity at GABAergic and glutamatergic synapses in the striatum is regulated by synaptic activityQ37140712
The cannabinoid system in Parkinson's disease: multiple targets to motor effectsQ37146722
Cannabinoid CB2 receptor agonists protect the striatum against malonate toxicity: relevance for Huntington's disease.Q37253331
WIN55,212-2, a cannabinoid receptor agonist, protects against nigrostriatal cell loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.Q37371387
The endocannabinoid system as a target for the treatment of motor dysfunctionQ37394164
The therapeutic potential of novel cannabinoid receptorsQ37402927
Distribution of neuronal cannabinoid receptor in the adult rat brain: a comparative receptor binding radioautography and in situ hybridization histochemistryQ38331458
Presynaptic specificity of endocannabinoid signaling in the hippocampusQ39750122
Enzymatic machinery for endocannabinoid biosynthesis associated with calcium stores in glutamatergic axon terminals.Q39831177
P433issue1
P921main subjectendocannabinoidsQ10483908
P304page(s)51-58
P577publication date2012-04-10
P1433published inProgress in Neuro-Psychopharmacology & Biological PsychiatryQ15616665
P1476titleNew insights on endocannabinoid transmission in psychomotor disorders
P478volume38

Reverse relations

cites work (P2860)
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Q27014154Modulation of the endocannabinoid system: vulnerability factor and new treatment target for stimulant addiction
Q37309718Peripheral endocannabinoid system dysregulation in first-episode psychosis

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