Anti-dyskinetic effects of cannabinoids in a rat model of Parkinson's disease: role of CB(1) and TRPV1 receptors.

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Anti-dyskinetic effects of cannabinoids in a rat model of Parkinson's disease: role of CB(1) and TRPV1 receptors. is …
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scholarly articleQ13442814

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P356DOI10.1016/J.EXPNEUROL.2007.07.021
P932PMC publication ID2128772
P698PubMed publication ID17900568
P5875ResearchGate publication ID5943343

P50authorAndrea GiuffridaQ42429689
Tommaso CassanoQ42689344
Maria Grazia MorgeseQ57080617
P2093author name stringVincenzo Cuomo
P2860cites workThe capsaicin receptor: a heat-activated ion channel in the pain pathwayQ24322558
Brain monoglyceride lipase participating in endocannabinoid inactivationQ24533828
Anandamide and vanilloid TRPV1 receptorsQ24672354
The cannabinoid WIN 55,212-2 inhibits transient receptor potential vanilloid 1 (TRPV1) and evokes peripheral antihyperalgesia via calcineurinQ24676808
A critical interaction between NR2B and MAGUK in L-DOPA induced dyskinesiaQ28569068
Expression and distribution of vanilloid receptor 1 (TRPV1) in the adult rat brainQ28570094
Modulation of anxiety through blockade of anandamide hydrolysisQ29615902
Pharmacological validation of behavioural measures of akinesia and dyskinesia in a rat model of Parkinson's disease.Q31039577
Animal models of neurological deficits: how relevant is the rat?Q31091605
Post- versus presynaptic plasticity in L-DOPA-induced dyskinesiaQ33255884
The spectrum of levodopa-induced dyskinesiasQ33890225
The endocannabinoid system as a target for therapeutic drugs.Q33934278
New perspectives on enigmatic vanilloid receptors.Q34046213
Modeling Parkinson's disease in rats: an evaluation of 6-OHDA lesions of the nigrostriatal pathwayQ34133059
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Oxidative metabolism of endocannabinoidsQ34673106
Distribution of mRNA for vanilloid receptor subtype 1 (VR1), and VR1-like immunoreactivity, in the central nervous system of the rat and humanQ35120095
The origin of motor fluctuations in Parkinson's disease: importance of dopaminergic innervation and basal ganglia circuits.Q35626716
Motor complications in Parkinson's disease and the clinical significance of rotational behavior in the rat: have we wasted our time?Q36352491
Distribution of cannabinoid receptors in the central and peripheral nervous system.Q36441196
The activity of anandamide at vanilloid VR1 receptors requires facilitated transport across the cell membrane and is limited by intracellular metabolismQ40817229
Dopamine activation of endogenous cannabinoid signaling in dorsal striatumQ41646203
A model of L-DOPA-induced dyskinesia in 6-hydroxydopamine lesioned mice: relation to motor and cellular parameters of nigrostriatal functionQ42463405
Role of striatal L-DOPA in the production of dyskinesia in 6-hydroxydopamine lesioned rats.Q42492136
Immunohistochemical localization of cannabinoid type 1 and vanilloid transient receptor potential vanilloid type 1 receptors in the mouse brainQ42493166
Endothelial proliferation and increased blood-brain barrier permeability in the basal ganglia in a rat model of 3,4-dihydroxyphenyl-L-alanine-induced dyskinesia.Q42501373
Endocannabinoid-mediated rescue of striatal LTD and motor deficits in Parkinson's disease modelsQ42508054
Characterization of enhanced behavioral responses to L-DOPA following repeated administration in the 6-hydroxydopamine-lesioned rat model of Parkinson's diseaseQ42541635
Compounds acting at the endocannabinoid and/or endovanilloid systems reduce hyperkinesia in a rat model of Huntington's diseaseQ42695373
Enhanced levels of endogenous cannabinoids in the globus pallidus are associated with a reduction in movement in an animal model of Parkinson's diseaseQ43504648
Unawareness of dyskinesias in Parkinson's and Huntington's diseasesQ43696853
Cannabinoids reduce levodopa-induced dyskinesia in Parkinson's disease: a pilot studyQ43820144
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Experimental parkinsonism alters endocannabinoid degradation: implications for striatal glutamatergic transmission.Q44102387
Ropinirole versus L-DOPA effects on striatal opioid peptide precursors in a rodent model of Parkinson's disease: implications for dyskinesiaQ44344002
Loss of bidirectional striatal synaptic plasticity in L-DOPA-induced dyskinesiaQ44383212
Presynaptic Facilitation of Glutamatergic Synapses to Dopaminergic Neurons of the Rat Substantia Nigra by Endogenous Stimulation of Vanilloid ReceptorsQ44418969
Dual effect of cannabinoid CB1 receptor stimulation on a vanilloid VR1 receptor-mediated responseQ44434119
Effects of levodopa on endocannabinoid levels in rat basal ganglia: implications for the treatment of levodopa‐induced dyskinesiasQ44597458
Levodopa-induced changes in synaptic dopamine levels increase with progression of Parkinson's disease: implications for dyskinesiasQ45030408
Characterization of the fatty acid amide hydrolase inhibitor cyclohexyl carbamic acid 3'-carbamoyl-biphenyl-3-yl ester (URB597): effects on anandamide and oleoylethanolamide deactivation.Q45173372
Transient receptor potential vanilloid subtype 1 mediates cell death of mesencephalic dopaminergic neurons in vivo and in vitro.Q45230637
A role for endocannabinoids in the generation of parkinsonism and levodopa-induced dyskinesia in MPTP-lesioned non-human primate models of Parkinson's diseaseQ46491157
Does contraversive circling in the 6-OHDA-lesioned rat indicate an ability to induce motor complications as well as therapeutic effects in Parkinson's disease?Q46591202
Endocannabinoids activate transient receptor potential vanilloid 1 receptors to reduce hyperdopaminergia-related hyperactivity: therapeutic implicationsQ46731448
Loss of synaptic D1 dopamine/N-methyl-D-aspartate glutamate receptor complexes in L-DOPA-induced dyskinesia in the rat.Q46859525
Increased slow oscillatory activity in substantia nigra pars reticulata triggers abnormal involuntary movements in the 6-OHDA-lesioned rat in the presence of excessive extracellular striatal dopamineQ46986296
Effect of bilateral 6-OHDA lesions of the substantia nigra on locomotor activity in the rat.Q48191276
Quantification of endocannabinoids in rat biological samples by GC/MS: technical and theoretical considerationsQ48378533
A role for vanilloid receptor 1 (TRPV1) and endocannabinnoid signalling in the regulation of spontaneous and L-DOPA induced locomotion in normal and reserpine-treated ratsQ60690596
Anandamide – the other side of the coinQ60690621
Effect of long-term therapy on the pharmacodynamics of levodopa. Relation to on-off phenomenonQ67588050
The cannabinoid agonists WIN 55,212-2 and CP 55,940 attenuate rotational behavior induced by a dopamine D1 but not a D2 agonist in rats with unilateral lesions of the nigrostriatal pathwayQ70973782
The endogenous cannabinoid receptor ligand, anandamide, inhibits the motor behavior: role of nigrostriatal dopaminergic neuronsQ72302141
Are cannabinoids endogenous ligands for the VR1 capsaicin receptor?Q73423096
Reversal of dopamine D(2) receptor responses by an anandamide transport inhibitorQ73704501
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectParkinson's diseaseQ11085
CNR2Q17907844
cannabinoid receptorQ421237
cannabinoidsQ422936
dyskinesiaQ629444
P304page(s)110-119
P577publication date2007-08-22
P1433published inExperimental NeurologyQ5421127
P1476titleAnti-dyskinetic effects of cannabinoids in a rat model of Parkinson's disease: role of CB(1) and TRPV1 receptors
P478volume208

Reverse relations

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