Cannabinoids in Parkinson's Disease

scientific article published on February 2017

Cannabinoids in Parkinson's Disease is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1089/CAN.2017.0002
P932PMC publication ID5436333
P698PubMed publication ID28861502

P50authorMario Alberto Ugo Stampanoni BassiQ85651614
Ennio IezziQ57310700
P2093author name stringDiego Centonze
Roberta Morace
Andrea Sancesario
P2860cites workInhibitory control of the GABAergic transmission in the rat neostriatum by D2 dopamine receptorsQ73465262
Reversal of dopamine D(2) receptor responses by an anandamide transport inhibitorQ73704501
N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptorQ21093349
Homosynaptic long-term depression in area CA1 of hippocampus and effects of N-methyl-D-aspartate receptor blockadeQ24561819
Human cannabinoid pharmacokineticsQ24652736
Looking for the role of cannabinoid receptor heteromers in striatal functionQ24658338
Cannabidiol: pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disordersQ26823267
Cannabis in the Treatment of Dystonia, Dyskinesias, and TicsQ27336419
Increased cannabinoid CB1 receptor binding and activation of GTP-binding proteins in the basal ganglia of patients with Parkinson's syndrome and of MPTP-treated marmosetsQ28203208
The enigmatic pharmacology of GPR55Q28235873
Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampusQ28268567
Cannabinoid action depends on phosphorylation of dopamine- and cAMP-regulated phosphoprotein of 32 kDa at the protein kinase A site in striatal projection neuronsQ28272251
The molecular logic of endocannabinoid signallingQ29615356
International Union of Pharmacology. XXVII. Classification of cannabinoid receptorsQ29616832
Self-reported efficacy of cannabis and other complementary medicine modalities by Parkinson's disease patients in colorado.Q30373216
Progress in understanding the factors regulating reversibility of long-term potentiationQ32113661
Cannabinoids go nuclear: evidence for activation of peroxisome proliferator-activated receptors.Q33845285
Pathophysiology of levodopa-induced dyskinesias in Parkinson's disease: problems with the current model.Q33890236
Endocannabinoid signaling in the brainQ34125520
Retrograde signaling in the regulation of synaptic transmission: focus on endocannabinoidsQ34166712
Cannabis and the brainQ34199483
Endocannabinoid signaling and synaptic functionQ34304094
Survey on cannabis use in Parkinson's disease: subjective improvement of motor symptomsQ34349067
Cannabis for dyskinesia in Parkinson disease: a randomized double-blind crossover studyQ34358022
Cannabis (medical marijuana) treatment for motor and non-motor symptoms of Parkinson disease: an open-label observational studyQ34409345
Evaluation of Phytocannabinoids from High Potency Cannabis sativa using In Vitro Bioassays to Determine Structure-Activity Relationships for Cannabinoid Receptor 1 and Cannabinoid Receptor 2Q34533857
Endocannabinoids and basal ganglia functionality.Q34673154
Cannabidiol for the treatment of psychosis in Parkinson's diseaseQ34830827
CB1 cannabinoid receptor signalling in Parkinson's diseaseQ35054346
Activation of PPAR gamma receptors reduces levodopa-induced dyskinesias in 6-OHDA-lesioned rats.Q35070472
Distribution of mRNA for vanilloid receptor subtype 1 (VR1), and VR1-like immunoreactivity, in the central nervous system of the rat and humanQ35120095
The therapeutic potential of cannabinoids for movement disordersQ35171113
Symptom-relieving and neuroprotective effects of the phytocannabinoid Δ⁹-THCV in animal models of Parkinson's diseaseQ35193305
The endocannabinoid system in the basal ganglia and in the mesolimbic reward system: implications for neurological and psychiatric disordersQ35586641
Endocannabinoid signaling and long-term synaptic plasticity.Q35679432
The cannabinoid agonist WIN55212-2 decreases L-DOPA-induced PKA activation and dyskinetic behavior in 6-OHDA-treated ratsQ35740152
GABA and Endocannabinoids Mediate Depotentiation of Schaffer Collateral Synapses Induced by Stimulation of Temperoammonic InputsQ35919442
Dopaminergic neurones: much more than dopamine?Q36198137
Anti-dyskinetic effects of cannabinoids in a rat model of Parkinson's disease: role of CB(1) and TRPV1 receptors.Q36248857
LTP forms 1, 2 and 3: different mechanisms for the "long" in long-term potentiationQ36733321
Biochemistry and pharmacology of endovanilloidsQ36756199
Dopamine-mediated regulation of corticostriatal synaptic plasticity.Q36762821
Independent presynaptic and postsynaptic mechanisms regulate endocannabinoid signaling at multiple synapses in the ventral tegmental area.Q36873051
Modulating the endocannabinoid system in human health and disease--successes and failuresQ36933683
Mechanisms of disease: basic-research-driven investigations in humans--the case of hyperkinetic disordersQ36959855
A role of p38 mitogen-activated protein kinase in adenosine A₁ receptor-mediated synaptic depotentiation in area CA1 of the rat hippocampusQ36963984
Presynaptic modulation by endocannabinoidsQ37026723
G protein-activated inwardly rectifying potassium channels mediate depotentiation of long-term potentiation.Q37034843
Endocannabinoid-mediated control of synaptic transmissionQ37363621
The endocannabinoid system as a target for the treatment of motor dysfunctionQ37394164
The endocannabinoid system: its general strategy of action, tools for its pharmacological manipulation and potential therapeutic exploitationQ37532968
Anandamide and the vanilloid receptor (TRPV1).Q37568663
Cannabinoids and Parkinson's disease.Q37617450
Cannabinoid-dopamine interaction in the pathophysiology and treatment of CNS disorders.Q37734568
Effects of rimonabant, a selective cannabinoid CB1 receptor antagonist, in a rat model of Parkinson's diseaseQ40358139
Marijuana for parkinsonian tremorQ41369366
Dopamine activation of endogenous cannabinoid signaling in dorsal striatumQ41646203
Identification of CB₂ receptors in human nigral neurons that degenerate in Parkinson's disease.Q41720746
D(2) dopamine receptors enable delta(9)-tetrahydrocannabinol induced memory impairment and reduction of hippocampal extracellular acetylcholine concentrationQ41833761
Detection of cannabinoid receptors CB1 and CB2 within basal ganglia output neurons in macaques: changes following experimental parkinsonismQ42095959
Adjuncts to dopamine replacement: a pragmatic approach to reducing the problem of dyskinesia in Parkinson's diseaseQ42464432
Unilateral 6-hydroxydopamine lesions of nigrostriatal dopaminergic neurons increased CB1 receptor mRNA levels in the caudate-putamenQ42487505
Endocannabinoid-mediated rescue of striatal LTD and motor deficits in Parkinson's disease modelsQ42508054
The effects of cannabinoid drugs on abnormal involuntary movements in dyskinetic and non-dyskinetic 6-hydroxydopamine lesioned ratsQ42871461
Enhanced striatal glutamate release after the administration of rimonabant to 6-hydroxydopamine-lesioned ratsQ43425029
Enhanced levels of endogenous cannabinoids in the globus pallidus are associated with a reduction in movement in an animal model of Parkinson's diseaseQ43504648
Cannabinoid receptor agonist and antagonist effects on motor function in normal and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP)-treated non-human primates.Q43683165
Cannabinoids reduce levodopa-induced dyskinesia in Parkinson's disease: a pilot studyQ43820144
Coexpression of the cannabinoid receptor type 1 with dopamine and serotonin receptors in distinct neuronal subpopulations of the adult mouse forebrain.Q43873792
Experimental parkinsonism alters endocannabinoid degradation: implications for striatal glutamatergic transmission.Q44102387
Stimulation of cannabinoid receptors reduces levodopa-induced dyskinesia in the MPTP-lesioned nonhuman primate model of Parkinson's diseaseQ44237885
Effects of CB1 cannabinoid receptor modulating compounds on the hyperkinesia induced by high-dose levodopa in the reserpine-treated rat model of Parkinson's diseaseQ44285779
Loss of bidirectional striatal synaptic plasticity in L-DOPA-induced dyskinesiaQ44383212
Levodopa treatment reverses endocannabinoid system abnormalities in experimental parkinsonismQ44418544
Effects of levodopa on endocannabinoid levels in rat basal ganglia: implications for the treatment of levodopa‐induced dyskinesiasQ44597458
Endocannabinoids mediate presynaptic inhibition of glutamatergic transmission in rat ventral tegmental area dopamine neurons through activation of CB1 receptors.Q44723162
Experimental parkinsonism alters anandamide precursor synthesis, and functional deficits are improved by AM404: a modulator of endocannabinoid functionQ44793025
A critical interaction between dopamine D2 receptors and endocannabinoids mediates the effects of cocaine on striatal gabaergic TransmissionQ44853701
Neurokinin B, neurotensin, and cannabinoid receptor antagonists and Parkinson diseaseQ44931450
Cannabinoid CB1 antagonists possess antiparkinsonian efficacy only in rats with very severe nigral lesion in experimental parkinsonismQ45310537
The CB(1) antagonist rimonabant is adjunctively therapeutic as well as monotherapeutic in an animal model of Parkinson's disease.Q46026291
High endogenous cannabinoid levels in the cerebrospinal fluid of untreated Parkinson's disease patients.Q46456086
A role for endocannabinoids in the generation of parkinsonism and levodopa-induced dyskinesia in MPTP-lesioned non-human primate models of Parkinson's diseaseQ46491157
Endocannabinoid signaling dynamics probed with optical tools.Q46750128
Therapeutic effects of Delta9-THC and modafinil in a marmoset Parkinson modelQ46789289
Effects of cannabidiol in the treatment of patients with Parkinson's disease: an exploratory double-blind trialQ48065074
Cannabidiol can improve complex sleep-related behaviours associated with rapid eye movement sleep behaviour disorder in Parkinson's disease patients: a case seriesQ48105623
Blockade of cannabinoid receptors by SR141716 selectively increases Fos expression in rat mesocorticolimbic areas via reduced dopamine D2 functionQ48189119
Endocannabinoids limit metabotropic glutamate 5 receptor-mediated synaptic inhibition of striatal principal neuronsQ48202452
Prolonged adenosine A1 receptor activation in hypoxia and pial vessel disruption focal cortical ischemia facilitates clathrin-mediated AMPA receptor endocytosis and long-lasting synaptic inhibition in rat hippocampal CA3-CA1 synapses: differential rQ48253332
Bidirectional long-term modification of synaptic effectiveness in the adult and immature hippocampusQ48258130
Endocannabinoids: endogenous cannabinoid receptor ligands with neuromodulatory actionQ48309971
Cannabinoid effects in basal ganglia in a rat model of Parkinson's diseaseQ48435185
Oleoylethanolamide reduces L-DOPA-induced dyskinesia via TRPV1 receptor in a mouse model of Parkinson´s diseaseQ48923652
Cannabinoid and dopamine interaction in rodent brain: effects on locomotor activity.Q49059668
Chronic L-DOPA treatment increases striatal cannabinoid CB1 receptor mRNA expression in 6-hydroxydopamine-lesioned ratsQ64814751
Dopaminergic regulation of cannabinoid receptor mRNA levels in the rat caudate-putamen: an in situ hybridization studyQ72656516
A role for extracellular adenosine in time-dependent reversal of long-term potentiation by low-frequency stimulation at hippocampal CA1 synapsesQ73176506
P433issue1
P921main subjectcannabinoidsQ422936
Parkinson's diseaseQ11085
P304page(s)21-29
P577publication date2017-02-01
P1433published inCannabis and cannabinoid researchQ27727510
P1476titleCannabinoids in Parkinson's Disease
P478volume2