Protective attenuated lentivirus immunization induces SIV-specific T cells in the genital tract of rhesus monkeys. (scientific article)

Simian-human immunodeficiency virus SHIV89.6-induced protection against intravaginal challenge with pathogenic SIVmac239 is independent of the route of immunization and is associated with a combination of cytotoxic T-lymphocyte and alpha interferon

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Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS

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HLA B*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors

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HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells

Q29616205

Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes

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Propagation and dissemination of infection after vaginal transmission of simian immunodeficiency virus

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Administration of an anti-CD8 monoclonal antibody interferes with the clearance of chimeric simian/human immunodeficiency virus during primary infections of rhesus macaques

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Critical role for CD4(+) T cells in controlling retrovirus replication and spread in persistently infected mice

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Identification of novel HLA-A2-restricted human immunodeficiency virus type 1-specific cytotoxic T-lymphocyte epitopes predicted by the HLA-A2 supertype peptide-binding motif

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CD8+ T-lymphocyte response to major immunodominant epitopes after vaginal exposure to simian immunodeficiency virus: too late and too little

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In situ tetramer staining

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Anti-HIV and -SIV immunity in the vagina

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Effective T-cell responses select human immunodeficiency virus mutants and slow disease progression

Q35857259

Antiviral antibodies are necessary for control of simian immunodeficiency virus replication

Q35857503

Vaginal transmission of chimeric simian/human immunodeficiency viruses in rhesus macaques

Q35860324

Rhesus macaques previously infected with simian/human immunodeficiency virus are protected from vaginal challenge with pathogenic SIVmac239.

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Live attenuated lentivirus infection elicits polyfunctional simian immunodeficiency virus Gag-specific CD8+ T cells with reduced apoptotic susceptibility in rhesus macaques that control virus replication after challenge with pathogenic SIVmac239.

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Induction of a virus-specific effector-memory CD4+ T cell response by attenuated SIV infection

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HIV-1 induces cytotoxic T lymphocytes in the cervix of infected women

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The strength of B cell immunity in female rhesus macaques is controlled by CD8+ T cells under the influence of ovarian steroid hormones

Q43975326

Langerhans cells, macrophages and lymphocyte subsets in the cervix and vagina of rhesus macaques

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Detection of antigen-specific T cell interferon gamma expression by ELISPOT and cytokine flow cytometry assays in rhesus macaques.

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Killing kinetics of simian immunodeficiency virus-specific CD8+ T cells: implications for HIV vaccine strategies

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Maintenance of large numbers of virus-specific CD8+ T cells in HIV-infected progressors and long-term nonprogressors

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Mechanisms of protection induced by attenuated simian immunodeficiency virus. II. Lymphocyte depletion does not abrogate protection.

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Protective immunity induced by live attenuated simian immunodeficiency virus

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P433

issue

P407

language of work or name

English

Q1860

P921

main subject

immunization

Q1415366

P304

page(s)

219-228

P577

publication date

2008-03-05

P1433

published in

Mucosal Immunology

Q15817743

P1476

title

Protective attenuated lentivirus immunization induces SIV-specific T cells in the genital tract of rhesus monkeys

P478

volume

Reverse relations

cites work (P2860)

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Q36155560	Antiviral antibodies and T cells are present in the foreskin of simian immunodeficiency virus-infected rhesus macaques
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Q36949843	With minimal systemic T-cell expansion, CD8+ T Cells mediate protection of rhesus macaques immunized with attenuated simian-human immunodeficiency virus SHIV89.6 from vaginal challenge with simian immunodeficiency virus.