Live attenuated lentivirus infection elicits polyfunctional simian immunodeficiency virus Gag-specific CD8+ T cells with reduced apoptotic susceptibility in rhesus macaques that control virus replication after challenge with pathogenic SIVmac239.

scientific article

Live attenuated lentivirus infection elicits polyfunctional simian immunodeficiency virus Gag-specific CD8+ T cells with reduced apoptotic susceptibility in rhesus macaques that control virus replication after challenge with pathogenic SIVmac239. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.4049/JIMMUNOL.179.7.4732
P932PMC publication ID3401023
P698PubMed publication ID17878372
P5875ResearchGate publication ID5965436

P2093author name stringJun Li
Christopher J Miller
Michael B McChesney
Tracy Rourke
Barinderpaul Chohan
Kristen Bost
Meritxell Genescà
P2860cites workVirus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infectionQ24645815
Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndromeQ24648628
Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cellsQ28215003
Central memory and effector memory T cell subsets: function, generation, and maintenanceQ29615097
HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cellsQ29616205
Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytesQ29616210
HIV-1-specific IFN-gamma/IL-2-secreting CD8 T cells support CD4-independent proliferation of HIV-1-specific CD8 T cells.Q33772204
Effect of CD8+ lymphocyte depletion on virus containment after simian immunodeficiency virus SIVmac251 challenge of live attenuated SIVmac239delta3-vaccinated rhesus macaquesQ33843308
Memory CD8 T-cell differentiation during viral infectionQ34152220
Mapping T cell epitopes by flow cytometryQ35119333
Increased mitochondrial mass characterizes the survival defect of HIV-specific CD8(+) T cellsQ35750901
HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic functionQ35834664
HIV and SIV CTL escape: implications for vaccine designQ35852284
Rhesus macaques previously infected with simian/human immunodeficiency virus are protected from vaginal challenge with pathogenic SIVmac239.Q35877932
Apoptosis in SIV infection.Q36092834
Depo-Provera abrogates attenuated lentivirus-induced protection in male rhesus macaques challenged intravenously with pathogenic SIVmac239.Q36105933
Dramatic rise in plasma viremia after CD8(+) T cell depletion in simian immunodeficiency virus-infected macaques.Q36368095
Impaired function of circulating HIV-specific CD8(+) T cells in chronic human immunodeficiency virus infection.Q40846408
Detection of antigen-specific T cell interferon gamma expression by ELISPOT and cytokine flow cytometry assays in rhesus macaques.Q44646604
Skewed maturation of memory HIV-specific CD8 T lymphocytesQ45284555
Preservation of functional virus-specific memory CD8+ T lymphocytes in vaccinated, simian human immunodeficiency virus-infected rhesus monkeysQ45417524
Contrasting effects of low-dose IL-2 on vaccine-boosted simian immunodeficiency virus (SIV)-specific CD4+ and CD8+ T cells in macaques chronically infected with SIVmac251.Q45514210
Dynamic immune responses maintain cytotoxic T lymphocyte epitope mutations in transmitted simian immunodeficiency virus variantsQ45516005
Emergence of CTL coincides with clearance of virus during primary simian immunodeficiency virus infection in rhesus monkeysQ45749710
Mechanisms of protection induced by attenuated simian immunodeficiency virus. II. Lymphocyte depletion does not abrogate protection.Q45753829
The functional profile of primary human antiviral CD8+ T cell effector activity is dictated by cognate peptide concentrationQ47643908
HIV-specific CD8+ T cells exhibit markedly reduced levels of Bcl-2 and Bcl-xL.Q47914791
Preapoptotic phenotype of viral epitope-specific CD8 T cells precludes memory development and is an intrinsic property of the epitope.Q51997310
Epitope affinity for MHC class I determines helper requirement for CTL priming.Q52021052
Increased CD95/Fas-induced apoptosis of HIV-specific CD8(+) T cells.Q55035589
Simian-human immunodeficiency virus SHIV89.6-induced protection against intravaginal challenge with pathogenic SIVmac239 is independent of the route of immunization and is associated with a combination of cytotoxic T-lymphocyte and alpha interferonQ72992207
Gene expression in antigen-specific CD8+ T cells during viral infectionQ73365714
The selective increase in caspase-3 expression in effector but not memory T cells allows susceptibility to apoptosisQ80884484
To kill or be killed: how HIV exhausts the immune systemQ81653120
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectapoptotic processQ14599311
attenuated vaccineQ1810913
Simian immunodeficiency virusQ1890246
P304page(s)4732-4740
P577publication date2007-10-01
P1433published inJournal of ImmunologyQ3521441
P1476titleLive attenuated lentivirus infection elicits polyfunctional simian immunodeficiency virus Gag-specific CD8+ T cells with reduced apoptotic susceptibility in rhesus macaques that control virus replication after challenge with pathogenic SIVmac239.
P478volume179

Reverse relations

cites work (P2860)
Q59349187A Lipid/DNA Adjuvant-Inactivated Influenza Virus Vaccine Protects Rhesus Macaques From Uncontrolled Virus Replication After Heterosubtypic Influenza A Virus Challenge
Q37704762A Mycobacterium bovis BCG-naked DNA prime-boost vaccination strategy induced CD4⁺ and CD8⁺ T-cell response against Mycobacterium tuberculosis immunogens
Q24633851Alphavirus replicon-based adjuvants enhance the immunogenicity and effectiveness of Fluzone ® in rhesus macaques
Q36105929Antiviral CD8+ T cells in the genital tract control viral replication and delay progression to AIDS after vaginal SIV challenge in rhesus macaques immunized with virulence attenuated SHIV 89.6.
Q36155560Antiviral antibodies and T cells are present in the foreskin of simian immunodeficiency virus-infected rhesus macaques
Q36539952Antiviral therapy during primary simian immunodeficiency virus infection fails to prevent acute loss of CD4+ T cells in gut mucosa but enhances their rapid restoration through central memory T cells
Q36846646CTLA-4 blockade increases antigen-specific CD8(+) T cells in prevaccinated patients with melanoma: three cases
Q37212827Cationic lipid/DNA complexes (JVRS-100) combined with influenza vaccine (Fluzone) increases antibody response, cellular immunity, and antigenically drifted protection
Q27320870Characterization of CD8+ T cell differentiation following SIVΔnef vaccination by transcription factor expression profiling
Q35250925Characterization of an effective CTL response against HIV and SIV infections
Q36808324Co-immunization with IL-15 enhances cellular immune responses induced by a vif-deleted simian immunodeficiency virus proviral DNA vaccine and confers partial protection against vaginal challenge with SIVmac251.
Q36996766Conditionally-live attenuated SIV upregulates global T effector memory cell frequency under replication permissive conditions
Q35758746DNA-Launched Alphavirus Replicons Encoding a Fusion of Mycobacterial Antigens Acr and Ag85B Are Immunogenic and Protective in a Murine Model of TB Infection
Q34072838Differential association of programmed death-1 and CD57 with ex vivo survival of CD8+ T cells in HIV infection
Q33558348Effective simian immunodeficiency virus-specific CD8+ T cells lack an easily detectable, shared characteristic
Q37395334Efficacy of influenza vaccination of elderly rhesus macaques is dramatically improved by addition of a cationic lipid/DNA adjuvant
Q36498230Emergence of polyfunctional CD8+ T cells after prolonged suppression of human immunodeficiency virus replication by antiretroviral therapy
Q37256687Evaluation of recombinant influenza virus-simian immunodeficiency virus vaccines in macaques
Q27323727High avidity CD8+ T cells efficiently eliminate motile HIV-infected targets and execute a locally focused program of anti-viral function
Q35806053Human CD4+ T Helper Cell Responses after Tick-Borne Encephalitis Vaccination and Infection
Q36154801Live-attenuated lentivirus immunization modulates innate immunity and inflammation while protecting rhesus macaques from vaginal simian immunodeficiency virus challenge.
Q37141704Long-term vaccine protection from AIDS and clearance of viral DNA following SHIV89.6P challenge
Q36484094Magnitude, breadth, and functional profile of T-cell responses during human immunodeficiency virus primary infection with B and BF viral variants
Q36827361Mucosal priming with a replicating-vaccinia virus-based vaccine elicits protective immunity to simian immunodeficiency virus challenge in rhesus monkeys
Q92610439Multifunctional cytokine production reveals functional superiority of memory CD4 T cells
Q37387085New insights on the role of apoptosis and autophagy in HIV pathogenesis
Q34976172Nonpathogenic CCR2-tropic SIVrcm after serial passage and its effect on SIVmac infection of Indian rhesus macaques
Q27024526Prime-boost approaches to tuberculosis vaccine development
Q36105923Protective attenuated lentivirus immunization induces SIV-specific T cells in the genital tract of rhesus monkeys.
Q37191912Recombinant Mycobacterium bovis BCG prime-recombinant adenovirus boost vaccination in rhesus monkeys elicits robust polyfunctional simian immunodeficiency virus-specific T-cell responses
Q35533181T cell receptor binding affinity governs the functional profile of cancer-specific CD8+ T cells
Q83455280Vaccine-induced anti-tuberculosis protective immunity in mice correlates with the magnitude and quality of multifunctional CD4 T cells
Q36949843With minimal systemic T-cell expansion, CD8+ T Cells mediate protection of rhesus macaques immunized with attenuated simian-human immunodeficiency virus SHIV89.6 from vaginal challenge with simian immunodeficiency virus.

Search more.