| scholarly article | Q13442814 |
| review article | Q7318358 |
| P356 | DOI | 10.1126/SCIENCE.1589757 |
| P698 | PubMed publication ID | 1589757 |
| P2093 | author name string | K. S. Kosik | |
| P433 | issue | 5058 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Alzheimer's disease | Q11081 |
| P304 | page(s) | 780-783 | |
| P577 | publication date | 1992-05-01 | |
| 1992-05-08 | |||
| P1433 | published in | Science | Q192864 |
| P1476 | title | Alzheimer's disease: a cell biological perspective | |
| P478 | volume | 256 |
| Q70975183 | A denaturant-insoluble form of tyrosine hydroxylase in PC12 pheochromocytoma cells |
| Q40779597 | A new hypothesis for the mechanism of amyloid toxicity, based on the calcium channel activity of amyloid beta protein (A beta P) in phospholipid bilayer membranes |
| Q48458099 | A novel antibody targeting sequence 31-35 in amyloid β protein attenuates Alzheimer's disease-related neuronal damage |
| Q48654619 | A spiropyran-based fluorescent probe for the specific detection of β-amyloid peptide oligomers in Alzheimer's disease |
| Q40319166 | A transitory activation of protein kinase-A induces a sustained tau hyperphosphorylation at multiple sites in N2a cells-imply a new mechanism in Alzheimer pathology |
| Q24300117 | AATF inhibits aberrant production of amyloid beta peptide 1-42 by interacting directly with Par-4 |
| Q43751849 | Aberrant induction of Par-4 is involved in apoptosis of hippocampal neurons in presenilin-1 M146V mutant knock-in mice |
| Q73043614 | Adriamycin induces apoptosis in rat thymocytes |
| Q40794805 | Altered tau and neurofilament proteins in neuro-degenerative diseases: diagnostic implications for Alzheimer's disease and Lewy body dementias |
| Q36433728 | Alzheimer disease A68 proteins injected into rat brain induce codeposits of beta-amyloid, ubiquitin, and alpha 1-antichymotrypsin |
| Q28262806 | Alzheimer disease amyloid beta protein forms calcium channels in bilayer membranes: blockade by tromethamine and aluminum |
| Q42916132 | Alzheimer's disease amyloid beta converting left-handed Z-DNA back to right-handed B-form |
| Q33906977 | Alzheimer's disease amyloid beta-protein forms Zn(2+)-sensitive, cation-selective channels across excised membrane patches from hypothalamic neurons |
| Q77601661 | Amyloid beta peptide is not a candidate for the neurotrophic activities released from chromaffin cells |
| Q30341746 | ApoE-dependent plasticity in Alzheimer's disease. |
| Q45758466 | Apoptosis as a mechanism of peripheral blood mononuclear cell death after measles and varicella-zoster virus infections in children |
| Q44795710 | Architecture of the Alzheimer's A beta P ion channel pore |
| Q40779580 | Biologically active domain of the secreted form of the amyloid beta/A4 protein precursor |
| Q41061846 | Brain parenchymal and microvascular amyloid in Alzheimer's disease |
| Q47628991 | Brain samples from Alzheimer's patients have elevated levels of loosely bound iron |
| Q42498400 | Brain-derived neurotrophic factor and neurotrophin-3 levels in Alzheimer's disease brains |
| Q40983033 | Cellular signaling pathways and cytoskeletal organization. |
| Q41075861 | Characterization of tau proteins in human neuroblastoma SH-SY5Y cell line. |
| Q38788038 | Cholinergic System and Post-translational Modifications: An Insight on the Role in Alzheimer's Disease |
| Q48389526 | Chronic lithium administration to FTDP-17 tau and GSK-3beta overexpressing mice prevents tau hyperphosphorylation and neurofibrillary tangle formation, but pre-formed neurofibrillary tangles do not revert. |
| Q38809381 | Co-assembly of polyoxometalates and peptides towards biological applications |
| Q48352514 | Colocalization of cholinesterases with beta amyloid protein in aged and Alzheimer's brains |
| Q34322737 | DNA microarrays in neuropsychopharmacology |
| Q58485375 | Dephosphorylation of tau protein and Alzheimer paired helical filaments by calcmeurin and phosphatase-2A |
| Q51606038 | Detection of mutations in PCR products from clinical samples by surface plasmon resonance. |
| Q48462144 | Developmental regulation and PKC dependence of Alzheimer's-type tau phosphorylations in cultured fetal rat hippocampal neurons |
| Q34173686 | Displacement currents associated with the insertion of Alzheimer disease amyloid beta-peptide into planar bilayer membranes |
| Q53311603 | Distribution of neuronal growth-promoting factors and cytoskeletal proteins in altered neurites in Alzheimer's disease and non-demented elderly |
| Q40623763 | Diverse distribution and function of fibrous microtubule-associated proteins in the nervous system. |
| Q36175993 | Dynamics of learning in cultured neuronal networks with antagonists of glutamate receptors |
| Q35773847 | E-4-hydroxy-2-nonenal is cytotoxic and cross-links cytoskeletal proteins in P19 neuroglial cultures |
| Q35121780 | Early disruption of the mother-infant relationship: effects on brain plasticity and implications for psychopathology. |
| Q34170437 | Extracellular proteolysis in the adult murine brain |
| Q52606045 | Fluoro-substituted cyanine for reliable in vivo labelling of amyloid-β oligomers and neuroprotection against amyloid-β induced toxicity. |
| Q43902835 | Formation of aberrant phosphotau fibrillar polymers in neural cultured cells |
| Q30408186 | Genetic and pharmacological evidence for schizophrenia-related Disc1 interaction with GSK-3. |
| Q34720291 | Genetic association of urokinase-type plasminogen activator gene rs2227564 site polymorphism with sporadic Alzheimer's disease in the Han Chinese population |
| Q35664175 | Glycated tau protein in Alzheimer disease: a mechanism for induction of oxidant stress |
| Q36973739 | Glycation exacerbates the neuronal toxicity of β-amyloid. |
| Q48394153 | Glycogen synthase kinase-3 and the Alzheimer-like state of microtubule-associated protein tau. |
| Q44645467 | Glycogen synthase kinase-3 plays a crucial role in tau exon 10 splicing and intranuclear distribution of SC35. Implications for Alzheimer's disease |
| Q42074371 | Guanosine induces necrosis of cultured aortic endothelial cells. |
| Q40246572 | Highly potent and specific GSK-3beta inhibitors that block tau phosphorylation and decrease alpha-synuclein protein expression in a cellular model of Parkinson's disease. |
| Q30442882 | Human antibodies reactive with beta-amyloid protein in Alzheimer's disease |
| Q45253429 | In situ monitoring Alzheimer's disease β-amyloid aggregation and screening of Aβ inhibitors using a perylene probe |
| Q35638734 | Increase of synaptic density and memory retention by a peptide representing the trophic domain of the amyloid beta/A4 protein precursor |
| Q48858835 | Inhibition of protein phosphatases induces IGF-1-blocked neurotrophin-insensitive neuronal apoptosis. |
| Q40794411 | Intracellular calcium changes in neuronal cells induced by Alzheimer's beta-amyloid protein are blocked by estradiol and cholesterol |
| Q41041853 | Ion channel hypothesis for Alzheimer amyloid peptide neurotoxicity |
| Q44079651 | Is a point mutation in the mitochondrial ND2 gene associated with Alzheimer's disease |
| Q26863513 | Lithium and autophagy |
| Q49162054 | Mice deficient for the amyloid precursor protein gene |
| Q40492240 | Microtubule-associated protein tau, paired helical filaments, and phosphorylation. |
| Q45233550 | Molecular determinants of the interaction between the C-terminal domain of Alzheimer's beta-amyloid peptide and apolipoprotein E alpha-helices |
| Q53178830 | More missense in amyloid gene. |
| Q53143766 | Morphology-Specific Inhibition of β-Amyloid Aggregates by 17β-Hydroxysteroid Dehydrogenase Type 10. |
| Q38809142 | Nanoparticles as potential clinical therapeutic agents in Alzheimer's disease: focus on selenium nanoparticles |
| Q34976296 | Neuroplasticity in Alzheimer's disease |
| Q40418259 | Novel functions of cholinesterases in development, physiology and disease |
| Q30417511 | Peptides in membranes: Helicity and hydrophobicity |
| Q77452193 | Photoaffinity study of the cellular interactions of ilimaquinone |
| Q53085028 | Photodegradation of β-sheet amyloid fibrils associated with Alzheimer's disease by using polyoxometalates as photocatalysts. |
| Q38189746 | Physicochemical bases for protein folding, dynamics, and protein-ligand binding |
| Q74664401 | Polymerization of tau peptides into fibrillar structures. The effect of FTDP-17 mutations |
| Q40949034 | Polymorphisms of the neurotrophic factor-3 (NTF-3) in Alzheimer's disease: rs6332 associated with onset time and rs6489630 T allele exhibited a protective role. |
| Q39571412 | Polyoxometalates as inhibitors of the aggregation of amyloid β peptides associated with Alzheimer's disease |
| Q36517139 | Potassium channel dysfunction in fibroblasts identifies patients with Alzheimer disease |
| Q48379496 | Proteins immunologically related to erythrocyte anion transporter band 3 are altered in brain areas affected by Alzheimer's disease |
| Q34141716 | Recognition between flexible protein molecules: induced and assisted folding |
| Q24530141 | Regulated phosphorylation and dephosphorylation of tau protein: effects on microtubule interaction, intracellular trafficking and neurodegeneration |
| Q40983024 | Regulation of tau phosphorylation in Alzheimer's disease |
| Q36342500 | Release of amyloid beta-protein precursor derivatives by electrical depolarization of rat hippocampal slices |
| Q35616076 | Secreted beta-amyloid precursor protein stimulates mitogen-activated protein kinase and enhances tau phosphorylation. |
| Q53201329 | Senile plaques stimulate microglia to release a neurotoxin found in Alzheimer brain |
| Q34940747 | Small molecule blockers of the Alzheimer Abeta calcium channel potently protect neurons from Abeta cytotoxicity |
| Q48161785 | Stereochemistry and amyloid inhibition: Asymmetric triplex metallohelices enantioselectively bind to Aβ peptide. |
| Q52080985 | Structural and functional characterization of 20S and 26S proteasomes from bovine brain. |
| Q36684459 | Structural model for the β-amyloid fibril based on interstrand alignment of an antiparallel-sheet comprising a C-terminal peptide |
| Q42160698 | Structure of heparan sulphate from human brain, with special regard to Alzheimer's disease |
| Q40554688 | The Alzheimer's disease sphinx: a riddle with plaques and tangles |
| Q87115428 | The neuroscience perspective and the changing role of the psychiatrist : the challenge for psychiatric educators |
| Q40578463 | The role of interleukin-6 in certain age-related diseases |
| Q41060580 | The significance of glucose turnover in the brain in the pathogenetic mechanisms of Alzheimer's disease |
| Q34018961 | Theoretical models of the ion channel structure of amyloid beta-protein |
| Q36073702 | Toward an understanding of the molecular mechanisms of physiological cell death. |
| Q42754605 | Twisted tubulofilaments of inclusion body myositis muscle resemble paired helical filaments of Alzheimer brain and contain hyperphosphorylated tau. |
| Q38875646 | Two macrocyclic polyamines as modulators of metal-mediated Aβ40 aggregation |
| Q64277486 | Using near-infrared enhanced thermozyme and scFv dual-conjugated Au nanorods for detection and targeted photothermal treatment of Alzheimer's disease |
| Q60693597 | Western Style Diet Impairs Entrance of Blood-Borne Insulin-like Growth Factor-1 into the Brain |
| Q40660449 | What is primary and what secondary for amyloid deposition in Alzheimer's disease |
| Q40616509 | beta-Amyloid Ca(2+)-channel hypothesis for neuronal death in Alzheimer disease |
| Q40779592 | beta-Amyloid precursor protein mismetabolism and loss of calcium homeostasis in Alzheimer's disease |
| Q46191598 | β‐Amyloid precursor epitopes in muscle fibers of inclusion body myositis |
Search more.