Functional coupling between secretory phospholipase A2 and cyclooxygenase-2 and its regulation by cytosolic group IV phospholipase A2

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Functional coupling between secretory phospholipase A2 and cyclooxygenase-2 and its regulation by cytosolic group IV phospholipase A2 is …
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scholarly articleQ13442814

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P819ADS bibcode1998PNAS...95.7951B
P356DOI10.1073/PNAS.95.14.7951
P932PMC publication ID20910
P698PubMed publication ID9653121
P5875ResearchGate publication ID13631906

P50authorMaría A BalboaQ44910438
Jesús BalsindeQ44910496
Edward A. DennisQ54261384
P2093author name stringE A Dennis
M A Balboa
P2860cites workDiversity of group types, regulation, and function of phospholipase A2Q28252971
Novel group V phospholipase A2 involved in arachidonic acid mobilization in murine P388D1 macrophagesQ28511451
Cytokine-stimulated secretion of group II phospholipase A2 by rat mesangial cells. Its contribution to arachidonic acid release and prostaglandin synthesis by cultured rat glomerular cellsQ33908899
Inhibition of calcium-independent phospholipase A2 prevents arachidonic acid incorporation and phospholipid remodeling in P388D1 macrophagesQ33989590
Arachidonic acid mobilization in P388D1 macrophages is controlled by two distinct Ca(2+)-dependent phospholipase A2 enzymesQ35893664
Regulation of prostaglandin E2 production in P388D1 macrophage-like cellsQ40572457
Mammalian non-pancreatic phospholipases A2.Q40770475
Prostaglandin synthase 2.Q40941854
Secretory phospholipases A2.Q41088057
Prostaglandin E2 amplifies cytosolic phospholipase A2- and cyclooxygenase-2-dependent delayed prostaglandin E2 generation in mouse osteoblastic cells. Enhancement by secretory phospholipase A2.Q41094611
Prostaglandin synthase-1 and prostaglandin synthase-2 are coupled to distinct phospholipases for the generation of prostaglandin D2 in activated mast cellsQ41128310
The incorporation of arachidonic acid into triacylglycerol in P388D1 macrophage-like cellsQ41233128
Exogenous type-II phospholipase A2 stimulates prostaglandin synthesis in rat liver-derived BRL-3A cells in the presence of tumor necrosis factor alphaQ41273927
Translocation of the 85-kDa phospholipase A2 from cytosol to the nuclear envelope in rat basophilic leukemia cells stimulated with calcium ionophore or IgE/antigenQ41333836
The growing phospholipase A2 superfamily of signal transduction enzymesQ41341078
Ligand-induced prostaglandin synthesis requires expression of the TIS10/PGS-2 prostaglandin synthase gene in murine fibroblasts and macrophages.Q41461889
A Reassessment of the Low Molecular Weight Phospholipase A2 Gene Family in MammalsQ41522207
Bacterial lipopolysaccharide priming of P388D1 macrophage-like cells for enhanced arachidonic acid metabolism. Platelet-activating factor receptor activation and regulation of phospholipase A2.Q41733805
Transcellular prostaglandin production following mast cell activation is mediated by proximal secretory phospholipase A2 and distal prostaglandin synthase 1.Q42817668
Distinct roles in signal transduction for each of the phospholipase A2 enzymes present in P388D1 macrophages.Q44816682
Analysis of the secretory phospholipase A2 that mediates prostaglandin production in mast cellsQ46096426
Inflammatory activation of arachidonic acid signaling in murine P388D1 macrophages via sphingomyelin synthesisQ46139243
Antisense inhibition of group II phospholipase A2 expression blocks the production of prostaglandin E2 by P388D1 cells.Q46236323
Molecular nature of phospholipases A2 involved in prostaglandin I2 synthesis in human umbilical vein endothelial cells. Possible participation of cytosolic and extracellular type II phospholipases A2Q70527465
Calcium-mediated translocation of cytosolic phospholipase A2 to the nuclear envelope and endoplasmic reticulumQ70808889
A heparin-sensitive phospholipase A2 and prostaglandin endoperoxide synthase-2 are functionally linked in the delayed phase of prostaglandin D2 generation in mouse bone marrow-derived mast cellsQ71574002
Type II secretory phospholipase A2 associated with cell surfaces via C-terminal heparin-binding lysine residues augments stimulus-initiated delayed prostaglandin generationQ71825106
Secretory phospholipase A2 generates the novel lipid mediator lysophosphatidic acid in membrane microvesicles shed from activated cellsQ72112725
Prostaglandin endoperoxide synthase-1 and -2 couple to different transmembrane stimuli to generate prostaglandin D2 in mouse bone marrow-derived mast cellsQ72152512
NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitroQ72321250
Evidence that secretory phospholipase A2 plays a role in arachidonic acid release and eicosanoid biosynthesis by mast cellsQ72432610
P433issue14
P407language of work or nameEnglishQ1860
P1104number of pages6
P304page(s)7951-7956
P577publication date1998-07-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleFunctional coupling between secretory phospholipase A2 and cyclooxygenase-2 and its regulation by cytosolic group IV phospholipase A2
P478volume95

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