Differential antibacterial properties of the MurA inhibitors terreic acid and fosfomycin

scientific article

Differential antibacterial properties of the MurA inhibitors terreic acid and fosfomycin is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/JOBM.201200617
P932PMC publication ID4610358
P698PubMed publication ID23686727

P2093author name stringErnst Schönbrunn
Yan Yang
Donna J Ingles
Sanne H Olesen
P2860cites workMurA (MurZ), the enzyme that catalyzes the first committed step in peptidoglycan biosynthesis, is essential in Escherichia coliQ24671787
The Fungal Product Terreic Acid Is a Covalent Inhibitor of the Bacterial Cell Wall Biosynthetic Enzyme UDP- N -Acetylglucosamine 1-Carboxyvinyltransferase (MurA),Q27660525
Structure of UDP-N-acetylglucosamine enolpyruvyl transferase, an enzyme essential for the synthesis of bacterial peptidoglycan, complexed with substrate UDP-N-acetylglucosamine and the drug fosfomycinQ27734363
Recent advances in the formation of the bacterial peptidoglycan monomer unitQ28204307
Identification and characterization of new inhibitors of the Escherichia coli MurA enzymeQ31016009
The mechanism of action of fosfomycin (phosphonomycin)Q34214482
Structure and function of the Mur enzymes: development of novel inhibitorsQ35030909
Evidence that the fosfomycin target Cys115 in UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) is essential for product releaseQ37866109
An array of Escherichia coli clones over-expressing essential proteins: a new strategy of identifying cellular targets of potent antibacterial compoundsQ38505082
Assessment and interpretation of bacterial viability by using the LIVE/DEAD BacLight Kit in combination with flow cytometryQ42121877
The UDP-N-acetylglucosamine 1-carboxyvinyl-transferase of Enterobacter cloacae. Molecular cloning, sequencing of the gene and overexpression of the enzymeQ42610701
Structure-activity relationships of tulipalines, tuliposides, and related compounds as inhibitors of MurA.Q42930172
The antibacterial properties of 6-tuliposide B. Synthesis of 6-tuliposide B analogues and structure-activity relationship.Q43235543
Phenyl thiazolyl urea and carbamate derivatives as new inhibitors of bacterial cell-wall biosynthesisQ43835367
The unusual binding mode of cnicin to the antibacterial target enzyme MurA revealed by X-ray crystallographyQ46450774
Alteration of a single amino acid residue reverses fosfomycin resistance of recombinant MurA from Mycobacterium tuberculosisQ47904411
Sesquiterpene lactones are potent and irreversible inhibitors of the antibacterial target enzyme MurA.Q54456599
Characterization of a Cys115 to Asp substitution in the Escherichia coli cell wall biosynthetic enzyme UDP-GlcNAc enolpyruvyl transferase (MurA) that confers resistance to inactivation by the antibiotic fosfomycin.Q54590227
P433issue4
P304page(s)322-326
P577publication date2013-05-20
P1433published inJournal of Basic MicrobiologyQ6294827
P1476titleDifferential antibacterial properties of the MurA inhibitors terreic acid and fosfomycin
P478volume54

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