| scholarly article | Q13442814 |
| P50 | author | Tom Curran | Q7815488 |
| Eric E. Zhang | Q38305591 | ||
| Ruediger Klein | Q63495755 | ||
| P2093 | author name string | Gen-Sheng Feng | |
| Barbara Ranscht | |||
| Dongmei Wu | |||
| Yuehai Ke | |||
| Yuhong Pang | |||
| Kazuki Hagihara | |||
| P2860 | cites work | Binding of Shp2 tyrosine phosphatase to FRS2 is essential for fibroblast growth factor-induced PC12 cell differentiation | Q24522542 |
| Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways | Q24529593 | ||
| Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3 | Q24600230 | ||
| Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation | Q24652976 | ||
| FGF-2-responsive neural stem cell proliferation requires CCg, a novel autocrine/paracrine cofactor | Q28141873 | ||
| Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells | Q28201183 | ||
| Neuronal Shp2 tyrosine phosphatase controls energy balance and metabolism | Q28511483 | ||
| Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice | Q28511962 | ||
| Essential role of Shp2-binding sites on FRS2alpha for corticogenesis and for FGF2-dependent proliferation of neural progenitor cells | Q28588997 | ||
| Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety | Q29615160 | ||
| Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells | Q29618944 | ||
| Control of CNS cell-fate decisions by SHP-2 and its dysregulation in Noonan syndrome | Q30479691 | ||
| Requirement of Shp-2 tyrosine phosphatase in lymphoid and hematopoietic cell development | Q31835063 | ||
| Biased suppression of hematopoiesis and multiple developmental defects in chimeric mice containing Shp-2 mutant cells | Q33781066 | ||
| Shp-2 tyrosine phosphatase: signaling one cell or many | Q33783500 | ||
| Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp-2. | Q33886525 | ||
| Impaired cerebral cortex development and blood pressure regulation in FGF-2-deficient mice | Q33889166 | ||
| Bmi1 loss produces an increase in astroglial cells and a decrease in neural stem cell population and proliferation. | Q34426800 | ||
| A positive autoregulatory loop of Jak-STAT signaling controls the onset of astrogliogenesis | Q34462655 | ||
| Reduced c-Myc signaling triggers telomere-independent senescence by regulating Bmi-1 and p16(INK4a). | Q34574445 | ||
| Self-renewal of hematopoietic and leukemic stem cells: a central role for the Polycomb-group gene Bmi-1 | Q35557266 | ||
| Cell surface heparan sulfate proteoglycan syndecan-2 induces the maturation of dendritic spines in rat hippocampal neurons | Q36255755 | ||
| A deletion mutation in the SH2-N domain of Shp-2 severely suppresses hematopoietic cell development | Q36572223 | ||
| A definitive role of Shp-2 tyrosine phosphatase in mediating embryonic stem cell differentiation and hematopoiesis | Q40641855 | ||
| Shp-2 has a positive regulatory role in ES cell differentiation and proliferation | Q41018537 | ||
| Interaction between NG2 proteoglycan and PDGF alpha-receptor on O2A progenitor cells is required for optimal response to PDGF. | Q41232375 | ||
| SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases | Q41566173 | ||
| Basic fibroblast growth factor (Fgf2) is necessary for cell proliferation and neurogenesis in the developing cerebral cortex. | Q42489532 | ||
| Changes in cerebral cortex size are governed by fibroblast growth factor during embryogenesis | Q47258812 | ||
| Ectopic expression of the bHLH gene Math1 disturbs neural development | Q48176906 | ||
| Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon | Q48265133 | ||
| Fibroblast growth factor 2 (FGF-2) promotes acquisition of epidermal growth factor (EGF) responsiveness in mouse striatal precursor cells: identification of neural precursors responding to both EGF and FGF-2. | Q48393528 | ||
| An essential role for a MEK-C/EBP pathway during growth factor-regulated cortical neurogenesis | Q48443396 | ||
| Regulation of gliogenesis in the central nervous system by the JAK-STAT signaling pathway | Q48617330 | ||
| FGF2 concentration regulates the generation of neurons and glia from multipotent cortical stem cells | Q48819870 | ||
| Multipotential stem cells from the adult mouse brain proliferate and self-renew in response to basic fibroblast growth factor. | Q49159036 | ||
| Role of Gab2 in mammary tumorigenesis and metastasis. | Q53336578 | ||
| bFGF regulates the proliferative fate of unipotent (neuronal) and bipotent (neuronal/astroglial) EGF-generated CNS progenitor cells | Q72608792 | ||
| P433 | issue | 19 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | neural stem cell | Q2944097 |
| P304 | page(s) | 6706-6717 | |
| P577 | publication date | 2007-07-23 | |
| P1433 | published in | Molecular and Cellular Biology | Q3319478 |
| P1476 | title | Deletion of Shp2 in the brain leads to defective proliferation and differentiation in neural stem cells and early postnatal lethality | |
| P478 | volume | 27 |
| Q89094774 | A complex of the ubiquitin ligase TRIM32 and the deubiquitinase USP7 balances the level of c-Myc ubiquitination and thereby determines neural stem cell fate specification |
| Q33418622 | A conserved mechanism for control of human and mouse embryonic stem cell pluripotency and differentiation by shp2 tyrosine phosphatase |
| Q50301379 | A familial case of LEOPARD syndrome associated with a high-functioning autism spectrum disorder |
| Q51887142 | A key role for Pak4 in proliferation and differentiation of neural progenitor cells. |
| Q36905741 | A tyrosine phosphatase SHP2 gain-of-function mutation enhances malignancy of breast carcinoma |
| Q33758337 | Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia |
| Q48908105 | Analysis of extracellular signal-regulated kinase 2 function in neural stem/progenitor cells via nervous system-specific gene disruption |
| Q35870390 | BMI-1, a promising therapeutic target for human cancer |
| Q36512624 | Central regulation of metabolism by protein tyrosine phosphatases |
| Q30442674 | Comprehensive behavioral analysis of cluster of differentiation 47 knockout mice |
| Q33637565 | Control of oligodendrocyte generation and proliferation by Shp2 protein tyrosine phosphatase |
| Q30629384 | Deletion of ERK2 mitogen-activated protein kinase identifies its key roles in cortical neurogenesis and cognitive function. |
| Q34611774 | Development of severe skeletal defects in induced SHP-2-deficient adult mice: a model of skeletal malformation in humans with SHP-2 mutations |
| Q37705054 | Distinct and overlapping functions of ptpn11 genes in Zebrafish development |
| Q38032488 | Dual faces of SH2-containing protein-tyrosine phosphatase Shp2/PTPN11 in tumorigenesis |
| Q36866432 | Eosinophil differentiation in the bone marrow is promoted by protein tyrosine phosphatase SHP2. |
| Q48302674 | EphB4 Regulates Self-Renewal, Proliferation and Neuronal Differentiation of Human Embryonic Neural Stem Cells in Vitro |
| Q34923711 | Essential role for Ptpn11 in survival of hematopoietic stem and progenitor cells |
| Q54313329 | Expression and significance of SHP-2 in human papillomavirus infected cervical cancer. |
| Q52646137 | Gain-of-function mutations in the gene encoding the tyrosine phosphatase SHP2 induce hydrocephalus in a catalytically dependent manner. |
| Q37238556 | Hepatocyte growth factor (HGF) signals through SHP2 to regulate primary mouse myoblast proliferation |
| Q35029942 | Kit-Shp2-Kit signaling acts to maintain a functional hematopoietic stem and progenitor cell pool |
| Q57818175 | Loss of Shp2 Rescues BDNF/TrkB Signaling and Contributes to Improved Retinal Ganglion Cell Neuroprotection |
| Q28586901 | Loss of Usp9x disrupts cortical architecture, hippocampal development and TGFβ-mediated axonogenesis |
| Q41647387 | MEK Is a Key Regulator of Gliogenesis in the Developing Brain. |
| Q40091029 | Macrophage-Restricted Shp2 Tyrosine Phosphatase Acts as a Rheostat for MMP12 through TGF-β Activation in the Prevention of Age-Related Emphysema in Mice. |
| Q39031139 | Modeling RASopathies with Genetically Modified Mouse Models. |
| Q93096512 | Neurodevelopmental Aspects of RASopathies |
| Q42964992 | Neurons or glia? Can SHP2 know it all? |
| Q38861759 | Noonan syndrome-associated SHP2 mutation differentially modulates the expression of postsynaptic receptors according to developmental maturation. |
| Q39917153 | Noonan syndrome/leukemia-associated gain-of-function mutations in SHP-2 phosphatase (PTPN11) enhance cell migration and angiogenesis |
| Q28396817 | Novel, real-time cell analysis for measuring viral cytopathogenesis and the efficacy of neutralizing antibodies to the 2009 influenza A (H1N1) virus |
| Q28477778 | Phenotypic pattern-based assay for dynamically monitoring host cellular responses to Salmonella infections |
| Q42591567 | Phosphatase-dependent and -independent functions of Shp2 in neural crest cells underlie LEOPARD syndrome pathogenesis |
| Q54354623 | Protein tyrosine phosphatase 1B is a regulator of the interleukin-10-induced transcriptional program in macrophages. |
| Q28646447 | Protein tyrosine phosphatases in the JAK/STAT pathway |
| Q33565458 | Protein tyrosine phosphatases, TC-PTP, SHP1, and SHP2, cooperate in rapid dephosphorylation of Stat3 in keratinocytes following UVB irradiation |
| Q39448315 | Recent advances in understanding the role of protein-tyrosine phosphatases in development and disease |
| Q38132066 | Receptor tyrosine kinase (RTK) signalling in the control of neural stem and progenitor cell (NSPC) development |
| Q24309381 | Receptor tyrosine phosphatase PTPγ is a regulator of spinal cord neurogenesis |
| Q54981177 | Regulation of Brain-Derived Neurotrophic Factor and Growth Factor Signaling Pathways by Tyrosine Phosphatase Shp2 in the Retina: A Brief Review. |
| Q43104640 | Regulation of rod photoreceptor differentiation by STAT3 is controlled by a tyrosine phosphatase. |
| Q36637278 | S-nitrosylated SHP-2 contributes to NMDA receptor-mediated excitotoxicity in acute ischemic stroke |
| Q36155130 | SH2 domain-containing phosphatase 2 is a critical regulator of connective tissue mast cell survival and homeostasis in mice |
| Q37701953 | SHP-2 deletion in postmigratory neural crest cells results in impaired cardiac sympathetic innervation |
| Q39298327 | SHP-2 phosphatase promotes cervical cancer cell proliferation through inhibiting interferon-β production |
| Q37186707 | SHP-2 tyrosine phosphatase in human diseases. |
| Q34634255 | SHP2 positively regulates TGFβ1-induced epithelial-mesenchymal transition modulated by its novel interacting protein Hook1. |
| Q47885098 | SHP2 regulates proliferation and tumorigenicity of glioma stem cells. |
| Q55488060 | SHP2-Mediated Signal Networks in Stem Cell Homeostasis and Dysfunction. |
| Q42556882 | Shp2 acts downstream of SDF-1alpha/CXCR4 in guiding granule cell migration during cerebellar development |
| Q36393427 | Shp2 plays an important role in acute cigarette smoke-mediated lung inflammation |
| Q38722719 | Shp2 promotes liver cancer stem cell expansion by augmenting β-catenin signaling and predicts chemotherapeutic response of patients. |
| Q37164220 | Shp2 suppresses the adipogenic differentiation of preadipocyte 3T3-L1 cells at an early stage |
| Q49167741 | Shp2-Mitogen-Activated Protein Kinase Signaling Drives Proliferation during Zebrafish Embryo Caudal Fin Fold Regeneration |
| Q28506451 | Shp2-dependent ERK signaling is essential for induction of Bergmann glia and foliation of the cerebellum |
| Q34245628 | Significance of SHP-1 and SHP-2 expression in human papillomavirus infected Condyloma acuminatum and cervical cancer |
| Q36629288 | Sorafenib and its derivative SC-49 sensitize hepatocellular carcinoma cells to CS-1008, a humanized anti-TNFRSF10B (DR5) antibody |
| Q39167357 | Src homology 2-containing protein tyrosine phosphatase-2 acts as a negative regulator for MUC5AC transcription via the inhibition of the ERK1/2 MAPK signalling pathway in the airway |
| Q36273603 | TRIM32 modulates pluripotency entry and exit by directly regulating Oct4 stability |
| Q64092255 | TRIM52 promotes colorectal cancer cell proliferation through the STAT3 signaling |
| Q38261370 | Targeting protein tyrosine phosphatase SHP2 for therapeutic intervention |
| Q33754710 | Temporal requirement of the protein tyrosine phosphatase Shp2 in establishing the neuronal fate in early retinal development |
| Q47926946 | The Molecular Pathway Regulating Bergmann Glia and Folia Generation in the Cerebellum |
| Q95841086 | The Phosphatase CSW Controls Life Span by Insulin Signaling and Metabolism Throughout Adult Life in Drosophila |
| Q24569665 | The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors |
| Q37617410 | The protein tyrosine phosphatase Shp2 is required for the generation of oligodendrocyte progenitor cells and myelination in the mouse telencephalon |
| Q37564987 | The protein tyrosine phosphatase, Shp2, positively contributes to FLT3-ITD-induced hematopoietic progenitor hyperproliferation and malignant disease in vivo |
| Q37342975 | The tyrosine phosphatase Shp2 (PTPN11) directs Neuregulin-1/ErbB signaling throughout Schwann cell development |
| Q37732956 | The tyrosine phosphatase Shp2 in development and cancer |
| Q34007299 | Tyrosine phosphatases Shp1 and Shp2 have unique and opposing roles in oligodendrocyte development |
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